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Advancing Cancer Surveillance in Less Resourced Settings Through Adaptation of SEER Analysis Tools
NAACCR 2018 Pittsburgh, PA June 14, 2018
Gonçalo Forjaz, Steve Scoppa, Dave Campbell, Sarah Quesnel-Crooks, Betsy Kohler, Glennis Andall-Brereton,
Damali Martin, Brenda Edwards
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Key metrics in cancer control.Mortality is a key
metric to measure progress against
cancer
NAACCR 2018 – June 14, 2018
Introduction
U.S. Mortality, NCHS, CDC
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Key metrics in cancer control.
NAACCR 2018 – June 14, 2018
Introduction
ComPrev CanSurv
Cancer surveillance
analytical tools
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NAACCR 2018 – June 14, 2018
Introduction
ComPrev CanSurv
SEER*Stat
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AGE YEAR SEX ICD-1056 2014 1 C34157 2014 1 C34158 2014 1 C34359 2014 1 C34960 2014 1 C34261 2014 1 C34062 2014 1 C341
AGE YEAR SEX ICD-1056 2014 1 C34157 2014 1 C34158 2014 1 C34359 2014 1 C34960 2014 1 C34261 2014 1 C34062 2014 1 C341
NAACCR 2018 – June 14, 2018
Introduction
One record per death
4-digit level COD
SEER*Stat
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NAACCR 2018 – June 14, 2018
Introduction
SEER*Prep SEER*Stat
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NAACCR 2018 – June 14, 2018
✓Added support for processing grouped data
✓Added a new Cause of Death recode based on 3-digit ICD-9 and ICD-10 codes
✓US cancer mortality data for 1979-2015 was compared to existing SEER Cause of Death Recode to validate the new classification
Methods
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AGE YEAR SEX ICD-10 DEATHS25‒29 2014 1 C34 4330‒34 2014 1 C34 5835‒39 2014 1 C34 6040‒44 2014 1 C34 6545‒49 2014 1 C34 7150‒54 2014 1 C34 8055‒59 2014 1 C34 95
AGE YEAR SEX ICD-10 DEATHS25‒29 2014 1 C34 4330‒34 2014 1 C34 5835‒39 2014 1 C34 6040‒44 2014 1 C34 6545‒49 2014 1 C34 7150‒54 2014 1 C34 8055‒59 2014 1 C34 95
NAACCR 2018 – June 14, 2018
Grouped data
3-digit level COD
SEER*Prep
Methods
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NAACCR 2018 – June 14, 2018
Methods
Lip, Oral Cavity and PharynxLip 140 C00 20010Tongue 141 C01-C02 20020Salivary Gland 142 C07-C08 20030Floor of Mouth 144 C04 20040Gum and Other Mouth 143, 145 C03, C05-C06 20050Nasopharynx 147 C11 20060Tonsil 146.0‒ 146.2 C09 20070Oropharynx 146.3‒146.9 C10 20080Hypopharynx 148 C12-C13 20090Other Oral Cavity and Pharynx 149 C14 20100
SEER Cause of Death Recode ‒ 4-digit ‒
Cancer Causes of Death
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NAACCR 2018 – June 14, 2018
Lip, Oral Cavity and PharynxLip 140 C00 20010Tongue 141 C01-C02 20020Salivary Gland 142 C07-C08 20030Floor of Mouth 144 C04 20040Gum and Other Mouth 143, 145 C03, C05-C06 20050Nasopharynx 147 C11 20060Tonsil 146.0‒ 146.2 C09 20070Oropharynx 146.3‒146.9 C10 20080Hypopharynx 148 C12-C13 20090Other Oral Cavity and Pharynx 149 C14 20100
Cancer Causes of Death
ICD-9 (1979-1998)
MethodsSEER Cause of Death Recode
‒ 4-digit ‒
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NAACCR 2018 – June 14, 2018
Lip, Oral Cavity and PharynxLip 140 C00 20010Tongue 141 C01-C02 20020Salivary Gland 142 C07-C08 20030Floor of Mouth 144 C04 20040Gum and Other Mouth 143, 145 C03, C05-C06 20050Nasopharynx 147 C11 20060Tonsil 146.0‒ 146.2 C09 20070Oropharynx 146.3‒146.9 C10 20080Hypopharynx 148 C12-C13 20090Other Oral Cavity and Pharynx 149 C14 20100
Cancer Causes of Death
ICD-9 (1979-1998)
ICD-10 (1999+)
MethodsSEER Cause of Death Recode
‒ 4-digit ‒
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NAACCR 2018 – June 14, 2018
Lip, Oral Cavity and PharynxLip 140 C00 20010Tongue 141 C01-C02 20020Salivary Gland 142 C07-C08 20030Floor of Mouth 144 C04 20040Gum and Other Mouth 143, 145 C03, C05-C06 20050Nasopharynx 147 C11 20060Tonsil 146.0‒ 146.2 C09 20070Oropharynx 146.3‒146.9 C10 20080Hypopharynx 148 C12-C13 20090Other Oral Cavity and Pharynx 149 C14 20100
Cancer Causes of Death
ICD-9 (1979-1998)
ICD-10 (1999+) Recode
MethodsSEER Cause of Death Recode
‒ 4-digit ‒
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NAACCR 2018 – June 14, 2018
Methods
IARC CI5 Grouping
CDC NCHS Translator
NCI SEER COD Recode
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NAACCR 2018 – June 14, 2018
Results
Lip, Oral Cavity and PharynxLip 140 C00 20010Tongue 141 C01-C02 20020Salivary Gland 142 C07-C08 20030Floor of Mouth 144 C04 20040Gum and Other Mouth 143, 145 C03, C05-C06 20050Nasopharynx 147 C11 20060Tonsil and Oropharynx 146 C09-C10 20070Hypopharynx 148 C12-C13 20090Other Oral Cavity and Pharynx 149 C14 20100
Cancer Causes of Death
ICD-9 (1979-1998)
ICD-10 (1999+) Recode
New SEER Cause of Death Recode ‒ 3-digit ‒
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NAACCR 2018 – June 14, 2018
Results
Digestive SystemOesophagus 150 C15 21010Stomach 151 C16 21020Small Intestine 152 C17 21030Colon and Rectum
Colon excluding Rectum 153, 159.0 C18, C26.0 21040Rectum and Rectosigmoid Junction 154.0‒154.1 C19-C20 21050
Anus, Anal Canal and Anorectum 154.2‒ 154.3, 154.8 C21 21060Liver and Intrahepatic Bile Duct
Liver 155.0, 155.2 C22.0, C22.2-C22.4, C22.7, C22.9 21071Intrahepatic Bile Duct 155.1 C22.1 21072
Gallbladder 156.0 C23 21080Other Biliary 156.1-156.2, 156.8-156.9 C24 21090Pancreas 157 C25 21100Retroperitoneum 158.0 C48.0 21110Peritoneum, Omentum and Mesentery 158.8-158.9 C48.1-C48.2 21120Other Digestive Organs 159.8-159.9 C26.8-C26.9, C48.8 21130
Cancer Causes of Death
ICD-9 (1979-1998)
ICD-10 (1999+) Recode
New SEER Cause of Death Recode ‒ 3-digit ‒
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NAACCR 2018 – June 14, 2018
Results
Digestive SystemOesophagus 150 C15 21010Stomach 151 C16 21020Small Intestine 152 C17 21030Large Bowel
Colon 153 C18 21040Rectum and Anus 154 C19-C21 21050
Liver and Intrahepatic Bile Duct 155 C22 21070Gallbladder and other Biliary 156 C23-C24 21080Pancreas 157 C25 21100Retroperitoneum, Peritoneum,Omentum and Mesentery 158 C48 21110
Cancer Causes of Death
ICD-9 (1979-1998)
ICD-10 (1999+) Recode
New SEER Cause of Death Recode ‒ 3-digit ‒
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NAACCR 2018 – June 14, 2018
Results
LymphomaHodgkin Lymphoma 201 C81 33010Non-Hodgkin Lymphoma 200, 202.0-202.2, 202.8-202.9 C82–86, C96.3 33040Leukemia
Lymphocytic LeukemiaAcute Lymphocytic Leukemia 204.0 C91.0 35011Chronic Lymphocytic Leukemia 204.1 C91.1 35012Other Lymphocytic Leukemia 202.4, 204.2, 204.8-204.9 C91.2-C91.4, C91.6-C91.9 35013
Myeloid and Monocytic Leukemia
Acute myeloid 205.0, 207.0, 207.2 C92.0, C92.4-C92.6, C92.8, C94.0, C94.2 35021
Acute Monocytic Leukemia 206.0 C93.0 35031Chronic Myeloid Leukemia 205.1 C92.1 35022
Other Myeloid/Monocytic Leukemia 205.2-205.3, 205.8-205.9, 206.1-206.2, 206.8-206.9
C92.2-C92.3, C92.7, C92.9, C93.1-C93.3, C93.7, C93.9 35023
Other LeukemiaOther Acute Leukemia 208.0 C94.4, C94.5, C95.0 35041
Aleukemic, subleukemic and NOS 203.1, 207.1, 207.8, 208.1-208.2, 208.8-208.9
C90.1, C91.5, C94.1, C94.3, C94.7, C95.1, C95.2, C95.7, C95.9 35043
Cancer Causes of Death
ICD-9 (1979-1998)
ICD-10 (1999+) Recode
New SEER Cause of Death Recode ‒ 3-digit ‒
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NAACCR 2018 – June 14, 2018
Results
Cancer Causes of Death
ICD-9 (1979-1998)
ICD-10 (1999+) Recode
LymphomaHodgkin Lymphoma 201 C81 33010Non-Hodgkin Lymphoma 200, 202 C82-C86, C96 33040Leukemia
Lymphoid Leukemia 204 C91 35011Myeloid Leukemia 205-207 C92-C94 35021Leukemia Unspecified 208 C95 35041
New SEER Cause of Death Recode ‒ 3-digit ‒
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NAACCR 2018 – June 14, 2018
Results
100% Correspondence
22 out of 26 non-cancer COD
35 out of 47 cancer COD
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NAACCR 2018 – June 14, 2018
ResultsAll Cancers
SEER COD Recode
‒ ICD-9 ‒ 140-208, 238.6 ‒ ICD-10 ‒
C00-C97
19,371,707 deaths
New SEER COD Recode
19,370,893 deaths
‒ ICD-9 ‒ 140-208
‒ ICD-10 ‒
C00-C97
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NAACCR 2018 – June 14, 2018
ResultsAll Cancers
3-digit
4-digit-0.7 (-0.8 to
-0.6)
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NAACCR 2018 – June 14, 2018
ResultsColorectal
SEER COD Recode
‒ ICD-9 ‒ 153-154, 159.0 ‒ ICD-10 ‒
C18-C21, C26.0
2,043,733 deaths
New SEER COD Recode
2,033,571 deaths
‒ ICD-9 ‒ 153-154
‒ ICD-10 ‒
C18-21
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NAACCR 2018 – June 14, 2018
ResultsColorectal
-2.0 (-2.1 to -1.8)
-1.8 (-2.0 to -1.6)
3-digit
4-digit
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NAACCR 2018 – June 14, 2018
ResultsLung
3-digit
4-digit
-0.5 (-0.6 to -0.4)
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NAACCR 2018 – June 14, 2018
ResultsNHL
3-digit
4-digit
-0.2 (-0.4 to -0.1)
-0.3 (-0.5 to -0.1)
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NAACCR 2018 – June 14, 2018
ResultsLeukemia
3-digit
4-digit
-0.8 (-1.0 to -0.6)
-0.7 (-0.9 to -0.5)
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NAACCR 2018 – June 14, 2018
✓ Improved features facilitate use of SEER analysis tools
✓The 3-digit classification matched almost all the ICD-9/ICD-10 groupings.
✓Confidentially restrictions are not an obstacle to data analysis
✓ Less-resourced settings are able to use limited data
Conclusion
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NAACCR 2018 Pittsburgh, PA June 14, 2018
Thank you!