Guideline No: 2008-8005 v5 Guideline: Acute Rhabdomyolysis - Investigation and Management This document reflects what is currently regarded as safe practice. However, as in any clinical situation, there may be factors which cannot be covered by a single set of guidelines. This document does not replace the need for the application of clinical judgement to each individual presentation. Approved by: SCHN Policy, Procedure and Guideline Committee Date Effective: 1 st March 2020 Review Period: 3 years Team Leader: Deputy Head Area/Dept: Genetic Metabolic Disorders Service Date of Publishing: 3 February 2021 10:34 AM Date of Printing: Page 1 of 10 K:\CHW P&P\ePolicy\Feb 21\Acute Rhabdomyolysis - Investigation and Management.docx This Guideline may be varied, withdrawn or replaced at any time. ACUTE RHABDOMYOLYSIS - INVESTIGATION AND MANAGEMENT PRACTICE GUIDELINE © DOCUMENT SUMMARY/KEY POINTS • Rhabdomyolysis can be due to a number of genetic and non-genetic causes, and may be associated with an acute life-threatening risk of electrolyte imbalance and/or acute renal failure. Early recognition, investigation and emergency management is vital. • This document provides a protocol for the evaluation and management of patients suspected of or at risk of having rhabdomyolysis, and should be used in consultation with the Genetic Metabolic Disorders Service, the Nephrology Department and ICU. It covers the following areas: o Patient history o Tests to confirm rhabdomyolysis o Investigations to monitor treatment o First line diagnostic investigations o Complex diagnostic investigations o Acute and long term management CHANGE SUMMARY • Mandatory review – No major changes • Updated references.
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