AcuityXpress™ High-Content Informatics Software

AcuityXpress 2 0 Installation Guide_guide.book Page 1 Wednesday, June 20, 2012 10:55 AM

AcuityXpress™ High-Content Informatics Software

Version 2.0

Installation Guide

0112-0150 CJune 2012

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Contents

Chapter 1: Software Installation Overview . . . . . . . . . . . 5Pre-Installation Note: Database Server Software . . . . . . . . 5Step 1: Installation of AcuityXpress 2.0 Software(New or Existing Users of AcuityXpress Software) . . . . . . . 5Step 2: For New Users of MDCStoreData Manager:Installation of MDCStore 2.0 Data Manager. . . . . . . . . . . . 6Step 3: For Existing Users of MDCStore Data Manager: Upgrade to MDCStore 2.0 Data Manager from an earlier version . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 6Step 4: Additional Materials Available for AcuityXpress Software Operation . . . . . . . . . . . . . . . . . . . . . . . . . . . . 7Step 5: Post-installation . . . . . . . . . . . . . . . . . . . . . . . . . 7

Chapter 2: Installing AcuityXpress 2.0 Software . . . . . . 9Installation Instructions . . . . . . . . . . . . . . . . . . . . . . . . . 9

Chapter 3: Installing the Hardware Protection Key . . . 11General Setup Information . . . . . . . . . . . . . . . . . . . . . . 11Step 1: Installing the Driver for the Hardware Protection Key . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 11Step 2: Installing the NetHASP License Manager . . . . . . . 12Step 3: Attach the Hardware Protection Key . . . . . . . . . . 12Step 4: Installing the Aladdin Monitor (Optional) . . . . . . . 12Network License Frequently Asked Questions . . . . . . . . . 13

Chapter 4: Running AcuityXpress Software. . . . . . . . . . 17Creating a Data Source. . . . . . . . . . . . . . . . . . . . . . . . . 17Connecting to the MDCStore 2.0 Data Manager for the First Time . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 18Recognizing the Hardware Protection Key on the Computer Running the AcuityXpress Software Client . . . . 18Checking for Updates of AcuityXpress 2.0 Software or MDCStore 2.0 Data Manager . . . . . . . . . . . . . . . . . . . . . 20

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Contents


Appendix A: Installing MSDE . . . . . . . . . . . . . . . . . . . . . 21Instructions . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 21

Appendix B: Installing the PDF Printer Driver . . . . . . . . 23Instructions . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 23

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Software Installation Overview

Pre-Installation Note: Database Server Software

To use AcuityXpress Software, MDCStore Data Manager, and MetaXpress Software, make sure the appropriate Database Server Software is installed.

• Databases up to 2 GB (in general, less than 5 plates worth of data): Use Microsoft SQL Server Desktop Engine (MSDE), which is a version of Microsoft SQL Server 2000 or 2005, suitable for desktop operation. MSDE can be installed from the AcuityXpress Software CD. See Appendix A: Installing MSDE on page 21 for detailed instructions.

• Databases larger than 2 GB: Customers must purchase Microsoft SQL Server 2000 or 2005, or Oracle 9.2 or 10 separately.

Step 1: Installation of AcuityXpress 2.0 Software(New or Existing Users of AcuityXpress Software)

The tools to install AcuityXpress 2.0 Software are available on the AcuityXpress Software CD. See Chapter 2: Installing AcuityXpress 2.0 Software on page 9 for detailed instructions.AcuityXpress 2.0 Software is compatible with MDCStore 2.0 Data Manager and MetaXpress 2.0 Software and later. Consult the MDCStore Installation Guide for the installation of MDCStore 2.0 Data Manager or its upgrade from an earlier version. For the installation of MetaXpress 2.0 Software or its upgrade from an earlier version, consult the MetaXpress 2.0 Software CD.

Note: The term “database” in this Installation Guide and in the installer refers to the MDCStore™ High Content Data Management Solution, which contains data generated by the ImageXpress® High-Content Analysis Systems, the MetaXpress® High-Content Image Acquisition & Analysis Software, and the AcuityXpress™ High-Content Informatics Software data, and is not to be confused with Microsoft SQL Server, MSDE, Oracle, or any other database server application.

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Step 2: For New Users of MDCStoreData Manager:Installation of MDCStore 2.0 Data Manager

AcuityXpress 2.0 Software is compatible with MDCStore 2.0 Data Manager and MetaXpress 2.0 Software (MetaXpress1.x Software versions are not compatible with MDCStore 2.0 Data Manager). The operation of AcuityXpress 2.0 Software requires the installation of MDCStore 2.0 Data Manager and MetaXpress 2.0 Software. MetaXpress 2.0 Software is available on a separate software CD.For new users of MDCStore Data Manager, the tools to install MDCStore 2.0 Data Manager on SQL or Oracle are available on the AcuityXpress Software CD. You must run the AcuityXpress Software CD on the computer on which you are creating the new database.

• Microsoft SQL Server users: See the section entitled “Install/Upgrade of MDCStore 2.0 on SQL Server” in the MDCStore Installation Guide for detailed instructions.

• Oracle Server users: See the section entitled “Install/Upgrade of MDCStore 2.0 on Oracle Server” in the MDCStore Installation Guide for detailed instructions.

Step 3: For Existing Users of MDCStore Data Manager: Upgrade to MDCStore 2.0 Data Manager from an earlier version

AcuityXpress 2.0 Software is compatible with MDCStore 2.0 Data Manager and MetaXpress 2.0 Software (MetaXpress 1.x Software versions are not compatible with MDCStore 2.0 Data Manager and higher). The operation of AcuityXpress 2.0 Software requires the upgrade to MDCStore 2.0 Data Manager and MetaXpress 2.0 Software. MetaXpress 2.0 Software is available on a separate software CD.

Note: It is recommended that you perform database tasks in the presence of a database administrator.

Note: Molecular Devices assumes no responsibility for any damage to existing user data that might occur due to network problems, power failure, unexpected termination during the update process, user customization of an existing MDCStore Database, or other reasons. You must have a full backup of your existing database before beginning an upgrade procedure.

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AcuityXpress 2.0 Software Installation Guide


• Existing users of MDCStore Data Manager using SQL Server: The tools to upgrade to MDCStore 2.0 Data Manager from an earlier version of MDCStore Data Manager on a SQL server are available on the AcuityXpress Software CD. For detailed instructions, see the section entitled “Install/Upgrade of MDCStore 2.0 on SQL Server” in the MDCStore Installation Guide.

• Existing users of MDCStore Data Manager using Oracle Server: Scripts for performing an upgrade to MDCStore 2.0 Data Manager from an earlier version of MDCStore Data Manager on Oracle are available on the AcuityXpress Software CD. For detailed instructions, see “Install/Upgrade of MDCStore 2.0 on Oracle Server” in the MDCStore Installation Guide.

Step 4: Additional Materials Available for AcuityXpress Software Operation

The following additional programs can facilitate the use of AcuityXpress Software and are available on the AcuityXpress Software CD:

• Adobe Acrobat Reader• PDF Printer driver

Step 5: Post-installation• The NetHASP License Manager software on the hardware

protection key server or the Aladdin Monitor can be installed from the AcuityXpress Software CD. For detailed instructions, see Chapter 3: Installing the Hardware Protection Key on page 11.

• Run AcuityXpress 2.0 Software for the first time on all client computers. For detailed instructions, see Chapter 4: Running AcuityXpress Software on page 17.

• Check for updates of AcuityXpress Software or MDCStore Data Manager: It is recommended that you use the latest available version of the AcuityXpress Software client and MDCStore Data Manager. To check for updates of AcuityXpress 2.0 Software, go to Help > MDC on the web > Download latest version.

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Installing AcuityXpress 2.0 Software

Installation InstructionsThese instructions will help you install AcuityXpress™ 2.0 Software and allow access to an existing local or remote MDCStore™ 2.0 Data Manager. If you need to install MDCStore Data Manager or upgrade it to version 2.0, see the MDCStore Installation Guide.

To install AcuityXpress Software

1. Insert the AcuityXpress 2.0 Software CD into your CD drive. If the meta-installer does not start automatically, open “My Computer,” browse to the CD drive, and then double-click the Setup icon.

2. In the AcuityXpress Software meta-installer dialog box, select Install AcuityXpress 2.0.

3. Click Yes to confirm installation of the AcuityXpress Software client on your system.

4. On the Welcome to AcuityXpress 2.0 Setup screen, click Next.5. On the email registration page, choose one of the following

actions: enter your name and email address (to be informed of

software updates), or click Next.

6. Select the installation directory by choosing one of the following: browse to a different directory, or accept the default directory.

7. Click Next.8. Select a program folder by choosing one of the following:

browse to a different folder, or accept the default folder location.

9. Click Next.10. If you have a previous version of AcuityXpress Software

installed, you might be asked to revert to factory defaults. If prompted to do so, it is recommended you revert to factory defaults to give the installation a clean start and to avoid any backwards compatibility issues.

11. Click Next.

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Installing AcuityXpress 2.0 Software


The HASP device driver installation dialog is displayed. The driver installation might take a few minutes.

12. Click Finish to restart your computer.After the system has been restarted, an AcuityXpress Software icon appears on your desktop and in the Start Menu > Molecular Devices > AcuityXpress group.

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Installing the Hardware Protection Key

A hardware protection key (also called a dongle) is used to prevent illegal use and distribution of software. The AcuityXpress™ Software USB NetHASP Hardware Protection Key is programmed with one or more AcuityXpress Software licenses and allows those licenses to be used on a network without requiring multiple hardware protection keys. It also permits centralized management of licenses within an organization.

General Setup InformationThe AcuityXpress Software hardware protection key can be connected to any computer on the network that supports USB. Choose a Windows computer that is always switched on and rarely rebooted, such as the MDCStore™ Data Manager database server.

Step 1: Installing the Driver for the Hardware Protection Key

If you install AcuityXpress Software on the computer that will have the hardware protection key attached, the drivers for the hardware protection key are automatically installed with AcuityXpress Software and you can go to Step 2: Installing the NetHASP License Manager. If you will only use AcuityXpress Software on other computers and do not want to install AcuityXpress Software on the computer that will have the hardware protection key attached, you need to install the driver manually. You can download the latest drivers at http://www.aladdin.com/support/hasp/enduser.asp

Note: If the hardware protection key is installed on a computer using the Microsoft Windows 2003 Server operating system, the dongle is not accessible from client computers running Windows XP. If your client computers are running Windows XP, we recommend that you install the dongle on a computer running Windows XP.

Note: Do not plug the hardware protection key into the computer before you install the driver. Doing so can result in Windows installing the wrong driver.

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Step 2: Installing the NetHASP License ManagerThe NetHASP License Manager software is a service that allows the use of AcuityXpress Software licenses by client computers on the network. Install the NetHASP License Manager software before you install the hardware protection key. If you are not planning to use the network key to serve licenses (for example, if you have only one key and will use the software on the computer with the key), omit step 2 and instead go to the next chapter.

To install the NetHASP License Manager

1. To access the AcuityXpress Software CD, in Windows Explorer, right-click on your PC’s CD drive, and then click Open.

2. In the \Network Dongle\ directory, select lmsetup.exe.3. In the HASP License Manager Installation dialog, select Next.4. Read and accept the End User License Agreement, and then

click Install.5. In the Installation Type dialog, select Service, and then click

Next.6. In the Choose Destination Location dialog box, click Next.7. In the Select Program Manager Group, leave the default setting,

and then click Next.8. In the XP SP2 Firewall Settings dialog, leave the default setting,

and then click Next.9. In the HASP License Manager dialog box, in the HASP License

Manager dialog box, select Yes, and then click Finish.10. Restart your computer.

Step 3: Attach the Hardware Protection KeyAfter installing AcuityXpress Software or manually installing the driver and installing the NetHASP License Manager, plug the hardware protection key into your computer.

Step 4: Installing the Aladdin Monitor (Optional)Aladdin Monitor is an application that is used to track network license usage. It can be installed on the computer that has the network hardware protection key installed or on a client computer on the network. You can use Aladdin Monitor to determine (by IP address) which computers have network licenses checked out.

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To install Aladdin Monitor

1. To access the AcuityXpress Software CD, in Windows Explorer, right-click on your PC’s CD drive, and then click Open.

2. In the \Hasp Monitor\ install\ directory, select aksmon32.exe. 3. In the Welcome dialog, click Next.4. In the Choose Destination Location dialog box, click Next (or

navigate to a different directory and then click Next).5. In the Backup Replaced Files dialog box, click Next (or browse

to a different directory and then click Next).6. In the Start Installation dialog box, click Next.7. Click Finish.

You can run Aladdin Monitor from the Start Menu > Programs > Aladdin directory.

Network License Frequently Asked Questions1. How does the network hardware protection key work?

There are two elements to a software protection system using a network hardware protection key: the license manager software and the client application. The license manager makes licenses available to the network. The number of licenses available depends on the total number programmed into the hardware protection key and those currently being used by clients on the network. When the client application is run, it searches the network for a license manager and requests a license. If there is a free license remaining in the hardware protection key, the license manager issues this to the client PC. When the client PC exits the application, the license is returned to the license manager and becomes available for other PCs on the network.For example, when AcuityXpress Software is run on a client PC, the AcuityXpress Software searches the network for a network license manager and requests a license. The license manager software allocates a license to each client PC, up to the maximum number of licenses available on that hardware protection key. If there are no available licenses on one hardware protection key, the AcuityXpress Software searches the network for other hardware protection keys. If none are found, the AcuityXpress Software reports to the user that a hardware protection key could not be found.

2. Can network hardware protection keys be combined(for example, 5-seat hardware protection key + 10-seat hardware protection key = 15 seats)?

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Yes, USB NetHASP hardware protection keys can be combined, on one or more computers.

3. Can a network license be accessed remotely using a dial-up connection?Yes, NetHASP works over a TCP connection. However, the computer that has the network hardware protection key attached has to be accessed remotely, through a secured gateway (for example, a VPN connection) or a hole in the firewall.

4. If the network goes down, can the network hardware protection key be moved to any other computer and used as a single-user license until the server is restored?Yes.

5. Does the hardware protection key track active use, or only whether the application is open (i.e., if a copy of AcuityXpress Software is open but minimized, does it still occupy a seat)?When the application is started, it occupies one seat until the program is closed, so minimizing the program still occupies a seat. If the computer crashes, the network license is still occupied. You must re-open the program on the same computer again and exit the program correctly for license to be returned. If the program does not re-start, running the Remove All and Load All menu commands in the license manager resets all licenses.

6. Is there a way to track which computers are using seats at any time (for example, if someone goes on vacation and leaves AcuityXpress Software running, can we locate the computer using that seat)?Yes. To display the IP address or name of every computer that has a license checked out, run the Aladdin Monitor software on the computer with the network hardware protection key installed, from the Start Menu > Programs > Aladdin directory.

7. What type of computer is required to install a network Hardware Protection Key? Is there a load on resources?The computer that has the hardware protection key installed does not need to be a server. There is no load on the system resources, so you can install it on the MDCStore Data Manager server or you can use another secure computer, if one is available. Because Windows NT does not support USB, the network hardware protection key must be attached to a computer running Windows 2000 or XP.

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8. My MDCStore Data Manager server is running Windows NT. How can I use a network hardware protection key? The database server does not need to be the network hardware protection key server. Install the network hardware protection key and license manager software on another computer running Windows 2000 or XP.

Note: If the hardware protection key is installed on a computer using the Microsoft Windows 2003 Server operating system, the dongle is not accessible from client computers running Windows XP. If your client computers are running Windows XP, we recommend that you install the dongle on a computer running Windows XP.

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Running AcuityXpress Software

Creating a Data SourceA data source is an alias to a database that includes information about the database type and therefore the database driver to use. The AcuityXpress™ Software includes a data source wizard that enables you to create a data source to an MDCStore™ Data Management Solution database.

To create a data source

1. Double-click the AcuityXpress Software desktop icon (or select AcuityXpress Software from the Start menu: Start Menu > Molecular Devices > AcuityXpress). The Data Source field is at the top of the AcuityXpress login dialog. If you have an existing AcuityXpress Software installation, you might already have a data source defined, so you do not need to define a new data source if you are connecting to the same database. You can have more than one data source to link to more than one MDCStore Data Management Solution database.

2. To create a new data source, click New Connection.3. Select one of the following: Microsoft SQL Server or Oracle.

In this example, we will use SQL Server.4. From the Computer list, select a computer name. All computers

running SQL Server that are accessible on your network are listed here. Some of them might not be MDCStore databases.

5. Type in your login name and password on the SQL Server installation to which you are attempting to connect, and click Connect.

6. On the Database Name list, select the MDCStore Data Management Solution database on the SQL Server installation that you have selected.

7. In the New Data Source field, type in a data source name. This is an alias for the new connection, so you can name it anything.

8. To create the data source, click Create.9. In the confirmation dialog box, click OK.

The AcuityXpress login dialog appears again, this time with the new data source name.

10. To run the AcuityXpress Software, click OK.

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To remove old data sources from the Data Source list in the AcuityXpress login dialog, use the Windows ODBC Data Sources management dialog available from Start menu: Start > Settings > Control Panel > Administrative Tools > Data Sources (ODBC) > System DSN.

Connecting to the MDCStore 2.0 Data Manager for the First Time

The first time you connect to an MDCStore Data Manager, if you are connecting to MS SQL Server database, you must use “sa” as a login name or, if you are connecting to Oracle, you must use “system” as a login name. You will then be required to change the passwords on two application-specific roles.Application-specific roles are used in a database to provide additional security to that provided by ordinary database accounts. For example, when a database implements application-specific roles, users cannot access the database through other software, such as the SQL Query Analyzer. They must access the database through the application.The passwords for the two application-specific roles are set only once, and are not required by ordinary users when using AcuityXpress Software. They should be set and recorded by the database administrator.

To connect to the database for the first time

1. Using AcuityXpress Software, log in to the new MDCStore Data Manager.

2. When prompted to change the password for the Everyone role, enter a new password in both the New Password and Confirm New Password fields.

3. Click OK.4. In the confirmation dialog, click OK.5. When prompted to change the password for the Administrators

role, enter a new password in both the New Password and Confirm New Password fields.

6. Click OK.7. In the confirmation dialog, click OK.

Recognizing the Hardware Protection Key on the Computer Running the AcuityXpress Software Client

Usually, the AcuityXpress Software automatically finds the network hardware protection key, if it is installed on another networked

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computer, and as long as the NetHASP License Manager is installed on the server. However, on some large networks or on networks with multiple workgroups, the AcuityXpress Software might have trouble automatically locating the network hardware protection key. If this happens, use the network hardware protection key locator.

To use the Network Hardware Protection Key Locator

1. Select Configure/Network Hardware Key Location. The Network Hardware Key Location dialog box appears.

2. Select one of the following options:Automatic (default): to find the server automatically, using the default setting, orDirect Connection: to manually select the server computer.

Figure 4-1 Network Hardware Key Location dialog box

3. Specify the server computer by doing one of the following: in the Computer field, enter the computer name or IP

address, or click Browse to browse for the computer on the network. Even if a computer is not listed in the network browser, if you enter its name or IP address in the Computer field, the key should be found. You can then click on the icon of the computer and click OK.

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If you click Browse, all available computers on your network are listed. It might take a few minutes for all computers to be found.

4. Exit the AcuityXpress Software for the change to take effect.The next time the AcuityXpress Software is opened, the client computer looks for the network hardware protection key on the specified computer. If the hardware protection key is moved from one computer to another, update the location on all of the necessary clients.

Checking for Updates of AcuityXpress 2.0 Software or MDCStore 2.0 Data Manager

It is recommended that you use the latest available version of the AcuityXpress 2.0 Software client and the MDCStore 2.0 Data Manager.

To check for updates

1. In the AcuityXpress 2.0 Software, select Help > MDC on the web > Download latest version.

2. If the Direct Connection option is used for detection of the Hardware protection key (see Recognizing the Hardware Protection Key on the Computer Running the AcuityXpress Software Client), reset the address after the update, because the update will restore the connection mode to Automatic (default).

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A


Installing MSDE

InstructionsThe AcuityXpress™ Software meta-installer includes a copy of Microsoft SQL Server Desktop Engine (MSDE). If you choose to use MSDE for your database application or for testing the demo version, then this is the first step of installation. MSDE cannot be installed if SQL Server 2000 or 2005 is already installed on your system.

To install MSDE

1. Insert the AcuityXpress Software CD into your CD drive. If the Installer program does not start automatically, open “My Computer”, browse to the CD-drive, and then double-click the Setup icon.

2. In the AcuityXpress Setup dialog, select 1. Microsoft SQL Server Desktop Engine.

3. When prompted, enter a password for the System Administrator account on MSDE. This is a password that you create, so you can enter anything. No other user interaction is required.

Note: The progress dialog can underestimate the time taken to install MSDE. This installation normally takes between 90 and 180 seconds. After the MSDE installation is complete, the Setup AcuityXpress dialog reappears.

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Installing MSDE


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Installing the PDF Printer Driver

InstructionsThe PDF printer driver included in the AcuityXpress™ Software meta-installer allows printing to the PDF file format. Within AcuityXpress Software, you can save directly to a PDF from several locations and you can also print to a PDF if you select “pdfFactory” as your printer, using File > Print Setup.

To install pdfFactory

1. Insert the AcuityXpress Software CD into your CD drive. If the Installer program does not start automatically, open “My Computer”, browse to the CD-drive, and then double-click the Setup icon.

2. In the AcuityXpress Setup dialog, select 3. PDF Printer Driver.3. In the FinePrint pdfFactory WinZip Self-Extractor, select Setup.4. When asked to install pdfFactory, select Yes.5. Read and accept the License Agreement.6. At the end of the installation, when asked to restart your

computer, select Yes.

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Installing the PDF Printer Driver


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AcuityXpress™ High-Content Informatics Software

Documents