Accelerating Anti-Retroviral Treatment as a catalytic action for Ending AIDS Pride Chigwedere, MD, PhD Senior Advisor to the African Union AWA CONSULTATIVE EXPERTS’ COMMITTEE MEETING OF COMMISSION OF THE AFRICAN UNION, NOUAKCHOTT, MAURITANIA 27-28 MAY 2014
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Accelerating Anti-Retroviral Treatment as a catalytic action for Ending AIDS
Accelerating Anti-Retroviral Treatment as a catalytic action for Ending AIDS. Pride Chigwedere , MD, PhD Senior Advisor to the African Union. AWA CONSULTATIVE EXPERTS’ COMMITTEE MEETING OF COMMISSION OF THE AFRICAN UNION, NOUAKCHOTT, MAURITANIA 27-28 MAY 2014. Calls for Ending AIDS. - PowerPoint PPT Presentation
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Accelerating Anti-Retroviral Treatment as a catalytic action for Ending AIDS
Pride Chigwedere, MD, PhDSenior Advisor to the African Union
AWA CONSULTATIVE EXPERTS’ COMMITTEE MEETING OF COMMISSION OF THE AFRICAN UNION,
NOUAKCHOTT, MAURITANIA27-28 MAY 2014
Calls for Ending AIDS
• Continental Calls Abuja + 12 Special SummitCommon African Position for
Post-2015 Agenda
• Global Calls MDGs2011 Political Declaration
• Is it possible to End AIDS?Progress in last decadeInterventions available
2011 UNGA Political Declaration - 2015 targets
1
Halve sexual transmission
2
Halve infections among injecting drug users
3
Eliminate new HIV infections among children and halve AIDS-related maternal deaths
4
15 million people on HIV treatment
5
Halve tuberculosis deaths among people living with HIV
10
Eliminate parallel systems, for stronger integration
9
Eliminate travel related restrictions
8
Eliminate stigma and discrimination
7
Eliminate gender inequalities and sexual violence and increase capacities of women and girls
6
Close the global resource gap and achieve annual investment of US$ 22-24 bn
Those with CD4≥500 worked nearly 1 week/month more than those with CD4<200, and as much as HIV-uninfected adults
Source: Thirurmurthy, Health Affairs, 2012
Rapid Treatment Scale up …
• Prevents death• Prevents active disease e.g. TB• PMTCT of HIV: Option B+• Prevents new HIV infection• Saves money and increases productivity • Lays the foundation for the end of the AIDS
epidemic
Scenarios of ARV eligibility: WHO vision
Source: WHO 2014
Source: UNAIDS estimates 2013
Gap in antiretroviral coverage varies within Africa
• 7.6 million people on ART in Africa• 21.2 million eligible under WHO 2013 Guidelines• 25 million people living with HIV on continent
UNAIDS PCB calls for new targets
• Targets drive progress• New scientific evidence• Post 2015• Accountability• A winnable challenge
Country and regional track: regional retargeting consultations
Continental AUC led processes
• July 2013 – Abuja + 12 Special Summit
• Nov 2013 – AUC/RECs Coordination Meeting
• Mar 2014 – Inter-Agency Meeting on AIDS
• May 2014 – AWA Experts Meeting
• June 2014 – AWA HoS Action Committee
Global trackPolitical stream
AU Partners Forum, 5-7 March
Vancouver TasP workshop political
day: high-level roundtable, 1 April
AIDS 2014: High-level panel, 20 July
Technical stream
Treatment 2015 Advisory
Committee meeting, 3 April
Price tag for the next targets, 7-8
April
Face-to-face meeting of the
UNAIDS Treatment Community, TBD,
June
Thematic stream
Treatment among young people and adolescents, 16-17
April
The perspective of the civil society on
the next targets, 14-15 May
The next paediatric treatment targets,
10-11 June
The Role of Laboratory
Medicine in the next treatment
targets, 16-17 June
Treatment cascade
Sources: 1. UNAIDS 2012 estimates; 2. Demographic and Health Surveys, 2007–2011(www.measuredhs.com); 3. Kranzer, K., van Schaik, N., et al. (2011), PLoS ONE;4. GARPR 2012; 5. Barth R E, van der Loeff MR, et al. (2010), Lancet Infect Disease.
Notes: No systematic data are available for the proportion of people living with HIV who are linked to care, although this is a vital step to ensuring viral suppression in the community .