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Date of preparation April 2014 │BRI001081 ACC.14 Annual Scientific Sessions of the American College of Cardiology Washington DC 29-31 March 2014
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ACC.14Annual Scientific Sessions of the American College of Cardiology

Washington DC

29-31 March 2014

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Disclaimer

• AstraZeneca abides by the Medicines Australia Code of Conduct (Edition 17) and AstraZeneca Global Policies, and as such will not engage in the promotion of unregistered products or unapproved indications.

• These highlights have been suggested by a group of cardiologists who attended ACC.14, compiled by an external medical writer and sponsored by AstraZeneca. 

• Statements of fact and opinions expressed are those of the speakers individually and, unless expressly stated to the contrary, are not the opinion or position of AstraZeneca. AstraZeneca does not endorse or approve, and assumes no responsibility for, the content, accuracy, or completeness of the information presented.  Presentations are intended for educational purposes only and do not replace independent professional judgement.

• Please refer to the appropriate approved Product Information before prescribing any agents mentioned in these highlights.

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ZEUS: Endeavour Sprint stent in uncertain DES candidates

Commentary:

Professor David BriegerConcord Hospital, Sydney

Late-breaking trial

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‘Personalised’ DAPT duration

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• The Endeavour DES is generally regarded as being superseded by newer technologies.

• The ZEUS study, however, suggests the Endeavour stent may have a role in patients who are uncertain candidates for a DES because of high bleeding or thrombosis risk or a low risk of stent thrombosis. ZEUS investigators suggest these patients constitute 30% of all-comers in real-world practice.

• The benefits of the Endeavour stent included an unexpected reduction in the risk of early and late stent thrombosis.

• It may be appropriate to re-introduce the Endeavour stent into practice, and tailor the duration of DAPT to individual patients’ risk features.

Commentary: Professor David Brieger