Prof FOMULU Joseph Nelson
Aug 18, 2015
Prof FOMULU Joseph Nelson
PLAN1. Definition2. Clinical types of abnormal uterine bleeding
1. Menorrhagia2. Hypomenorrhoea3. Metrorrhagia4. Polymenorrhoea5. Menometrorrhagia6. Oligomenorrhoea7. Contact bleeding8. Amenorrhoea9. Dysmenorrhoea
3. Evaluation of abnormal bleeding1. Clinical history2. Physical exam3. Investigations
4. General principles of management
1- Definition• Any bleeding from uterus that differs
materially from that of the normal menstrual cycle in frequency of occurrence, in amount or in duration of flow.
• It applies to both menstrual and non menstrual disturbances due to– Organic disease either benign or malignant– Or to systemic or psychogenic origin
• Between menarche and menopause, almost every woman experiences one or more episodes of abnormal uterine bleeding.
2- Clinical types of abnormal uterine bleeding
Menorrhagia (hypermenorrhoea)Cyclical menstrual bleeding excessive in amount
and/ or prolonged in durationCauses:
Uterine fibroids Complication of undiagnosed pregnancy Adenomyosis Endometrial hyperplasia Malignant tumours Endometritis Dysfunctional bleeding
2- Clinical types of abnormal uterine bleeding Hypomenorrhoea (cryptomenorrhoea)
An abnormally small amount of menstrual flow usually spotting
Causes: Cervical stenosis Congenital transverse vaginal membrane Asherman syndrome Endometrial tuberculosis
PolymenorrhoeaPeriods occurring too frequently, usually less than
21 days apart. Bleeding may or may not be abnormal in amount
Causes: anovulation (endocrine disorders)
2- Clinical types of abnormal uterine bleeding
Metrorrhagia (intermenstrual bleeding)Bleeding occuring at any time between
menstrual periods ranging from slight spotting to haemorragic flow and from a single short episode to bleeding that continues for days
Causes: Endometrial polyps Endometrial and cervical cancers Exogenous oestrogen administration
2- Clinical types of abnormal uterine bleeding Menometrorrhagia
Uterine bleeding totally irregular in frequency and duration of episodes and excessive in amount.
Causes: Complications of pregnancy (abortion, hydatoform
mole, choriocarcinoma) Malignant genital tract tumours
OligomenorrhoeaMenstrual periods that occur more than 35
days apart. Bleeding usually decreased in amount and duration
Causes: Menopause, Anovulation, Pregnancy complications, Oestrogen-producing tumors
2- Clinical types of abnormal uterine bleeding Contact bleeding
Self-explanatoryCauses:
Cervicitis Cervical cancer Cervical eversion (ectropion) Cervical polyps
Amenorrhoea Failure to menstruate which is:
Physiology (before puberty, during pregnancy, puerperum and after menopause)
Pathological Primary amenorrhoea: congenital malformations, genetic
disorders. Secondary amenorrhoea
2- Clinical types of abnormal uterine bleeding
DysmenorrhoeaPainful menstruation, the commonest
gynaecological complaint, and leading cause of absenteism primary dysmenorrhoea: idiopathic causes (theories) secondary dysmenorrhoea: organic disease (PID,
endometriosis, fibroids, ...)
3- Evaluation of abnormal uterine bleeding Clinical history
Many causes of bleeding will be strongly suggested by history alone.
Note amount of flow, duration of cycle, duration of periods, number of episodes, LMP, menopause and any change in general health
Physical examinationGeneral health conditionGlandsAbdominal massesSize of the uterus/ovariesCervix
Evaluation of abnormal uterine bleeding
InvestigationsPap smearEndometrial BiopsyHysteroscopyD & CHormonal assaysUltrasoundLaparoscopy
4- General principles of management
A careful clinical history, physical and pelvic examination are vital.
Improved diagnostic technics and treatment have resulted in better care of patients with abnormal uterine bleeding.
ReferencesIntegrated Obstetrics and Gynaecology for
postgraduates by C.J. Dewhurst, 2nd edition by Blackwell Scientific Publications.
Obstetrics and Gynaecology (Scientific Foundations of) by Elliot E Philipp, Josephine Barns and Michael Newton International Edition (3rd edition)
Principles of Gynaecology, by Sir Norman Jeffwate, Butterworths, 4th edition.