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ANTI BIOTIKAPENISILIN
DRS JUZRAL JIVAI MS APT
FAKULTAS KEDOKTERANUNIVERSITAS BAITURRAHMAH
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AM AM
M H
SIFAT SIFAT M
MEKANISME KERJA DOSIS AM WAKTU PEMBERIAN AM
CARA PEMBERIAN AM LAMA PEMBERIAN AM KEADAAN FISIK H
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Makrop./Monosi ran!san! A! I"#no!$nik S$% Li"&oi' S$% I"#no
ko"p$$n (S$% B 'an S$% T)
◦ R$spon I"#n H#"ora%
◦ Ran!san! Di&r$/Pro%i
Konak S$% B S$% P%as"a A*
R$spon I"#n S$%#%$r Ran!san! Di&r$/Pro%i
Konak S$% T S$nsi. S$% T Li"&okin
S$% M$"ori
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1S CH3 NH2–6 CH 7CH 2C – CH3
β α O = 5C N 3CH – COOH
C!H12O3N2S
6"A#$%& P'%$($)$%*+ ,6"APA-
α = CINCIN TIA.OLIDIN β = CINCIN β "LAKTAM
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S CH3 +H,.-H.-O/NH – CH CH C – CH3
O = C N CH – COOH
C16H1!N2OS
B'%0$) P'%$($)$% = P'%$($)$%
S CH3 -+H,.-H(NH).-O/NH – CH CH C – CH3
O = C N CH – COOH C16H1N3OS A#$($)$%
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PENEMU I PENISILIN FLEMIN ,12!- LONDON FLORE4 UNI/ OFORD O*+ +'8*$ S$(+'#$9
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N*($)$% N* ,('#$($%+'+$9-
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1S
NH2–7CH !CH 2CH2 β α O = 6C 5N 3C – CH2/O/CO/CH3 C – COOH
C1GH12N2O5S
7" *#$%& S'*)&(&8$%*+ ,7 – ACA-
α = C$%:$% D$
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S'*)&(&8$%*(' ?*8$ K)'($')* 8$%*% +'8
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TERIMA KASIH