Top Banner
sp5 A–8879 B.Sc. DEGREE EXAMINATION, NOVEMBER 2019 Third Semester Biochemistry ENZYMOLOGY (CBCS – 2014 onwards) Time : 3 Hours Maximum : 75 Marks Part A (10 2 = 20) Answer all questions. 1. What are enzymes? ö|õvPÒ GßÓõÀ GßÚ? 2. Define specific activity of enzymes. ö|õvPÐøh¯ SÔ¨¤mh ö\¯À£õkPÒ GߣuøÚ Áøμ¯Ö. 3. Write a brief note on proximity effect. ¤μõU]ªmi ÂøÍÄ £ØÔ _¸UP©õP GÊxP. 4. What are coenzymes? Give examples. xøn ö|õvPÒ GßÓõÀ GßÚ? Euõμn[PÒ u¸P. 5. Define enzyme inhibition. ö|õv uk¨¦ GߣuøÚ Áøμ¯Ö. 6. What is enzyme catalysis? ö|õv ÂøÚzyshÀ GßÓõÀ GßÚ? Sub. Code 4BBC3C1
28

A–8879 Sub. Code 4BBC3C1

Oct 16, 2021

Download

Documents

dariahiddleston
Welcome message from author
This document is posted to help you gain knowledge. Please leave a comment to let me know what you think about it! Share it to your friends and learn new things together.
Transcript
Page 1: A–8879 Sub. Code 4BBC3C1

sp5

A–8879

B.Sc. DEGREE EXAMINATION, NOVEMBER 2019

Third Semester

Biochemistry

ENZYMOLOGY

(CBCS – 2014 onwards)

Time : 3 Hours Maximum : 75 Marks

Part A (10 2 = 20)

Answer all questions.

1. What are enzymes?

ö|õvPÒ GßÓõÀ GßÚ?

2. Define specific activity of enzymes.

ö|õvPÐøh¯ SÔ¨¤mh ö\¯À£õkPÒ GߣuøÚ Áøμ¯Ö.

3. Write a brief note on proximity effect.

¤μõU]ªmi ÂøÍÄ £ØÔ _¸UP©õP GÊxP.

4. What are coenzymes? Give examples.

xøn ö|õvPÒ GßÓõÀ GßÚ? Euõμn[PÒ u¸P.

5. Define enzyme inhibition.

ö|õv uk¨¦ GߣuøÚ Áøμ¯Ö.

6. What is enzyme catalysis?

ö|õv ÂøÚzyshÀ GßÓõÀ GßÚ?

Sub. Code 4BBC3C1

Page 2: A–8879 Sub. Code 4BBC3C1

A–8879

2

sp5 7. Define the term centrifugation.

ö\ßm›¦÷Påß GߣuøÚ Áøμ¯Ö.

8. What is isoelectric pH?

I÷\õ G»Um›U pH GßÓõÀ GßÚ?

9. Write briefly about lactase.

»õU÷hì £ØÔ _¸UP©õP GÊxP.

10. Write any two role of proteases in textile industry.

BøhPÒ EØ£zv öuõÈØ\õø»°À ¦÷μõmj÷¯]Ýøh¯

H÷uÝ® Cμsk £¯ßPøÍ GÊxP.

Part B (5 5 = 25)

Answer all questions, choosing either (a) or (b).

11. (a) Discuss about the General characteristics of enzymes.

ö|õvPÎß ö£õx¨ £s¦PÒ £ØÔ ÂÁõv.

Or

(b) Give an account of multi enzyme complexes.

£» ö|õv Tmhø©¨¦PÒ £ØÔ GÊxP.

12. (a) Explain the mechanism of action of lysozyme.

ø»÷\õø\ªß ÂøÚ ÁÈ•øÓPøÍ ÂÁ›.

Or

(b) Discuss about covalent catalysis.

÷Põ÷Á»ßm ÂøÚ£õk £ØÔ ÂÁ›.

Page 3: A–8879 Sub. Code 4BBC3C1

A–8879

3

sp5 13. (a) Give an account of LB plot.

LB ¤Íõm £ØÔ Â›ÁõÚ ÂÍUP® u¸P.

Or

(b) Discuss about the factors affecting enzyme activity.

ö|õv ÂøÚ°øÚ¨ £õvUS® PõμoPÒ £ØÔ ÂÁ›.

14. (a) Write about the enzyme separation based on solubility precipitation methods.

PøμvÓß Ai¨£øh°À ÃÌ£iÁõuÀ •øÓ°À

ö|õv¨ ¤›zöukzuø»¨ £ØÔ GÊxP.

Or

(b) Describe the homogenization method in enzyme purification.

÷íõ÷©õâøÚ÷\åß •øÓ°À ö|õv

_zu¨£kzxuø» ÂÁ›.

15. (a) Write in detail about diagnostic and therapeutic enzymes.

÷|õ´U PshÔuÀ ©ØÖ® ÷|õ´USn¨£kzxu¼À

ö|õvPÎß £[S £ØÔ ÂÁ›zx GÊxP.

Or

(b) Discuss the enzyme electrodes.

ö|õv G»Um÷μõkPÒ £ØÔ ÂÁ›.

Part C (3 10 = 30)

Answer any three questions.

16. Explain the IUB enzyme classification with examples.

ö|õvPÎß IUB ÁøP¨£õmiøÚ Euõμn[PÐhß ÂÁ›.

Page 4: A–8879 Sub. Code 4BBC3C1

A–8879

4

sp5 17. Discuss about the structure and functions of nicotinamide

coenzyme.

{÷PõiÚø©k xøn ö|õv°ß Aø©¨¦ ©ØÖ®

ö\¯ÀPøͨ £ØÔ ÂÁ›.

18. Derive the Michaelis – Menten equation.

ø©Põ¼ì – ö©ßhß \©ß£õmiøÚ u¸Â.

19. Explain the method of enzyme separation by dialysis and ultrafiltration.

h¯õø»]ì ©ØÖ® AÀmμõ ¤Àm÷μåß •øÓ°À ö|õv

¤›zöukzuø» ÂÁ›.

20. Write about the applications of proteases in food, detergent and leather industry.

EnÄ, ÷\õ¨¦ ©ØÖ® ÷uõÀ öuõÈØ\õø»°À ¦÷μõmi÷¯\ì

ö|õvPÎß £¯ß£õkPøͨ £ØÔ GÊxP.

————————

Page 5: A–8879 Sub. Code 4BBC3C1

Wk ser

A–8880

B.Sc. DEGREE EXAMINATION, NOVEMBER 2019

Third Semester

Biochemistry

INTERMEDIARY METABOLISM

(CBCS – 2014 onwards)

Time : 3 Hours Maximum : 75 Marks

Part A (10 2 = 20)

Answer all questions.

1. Write a brief note on amphibolic pathway.

B®¨¤÷£õ¼U ÁÈ•øÓ¨ £ØÔ GÊxP.

2. What is gluconeogenesis?

SÐU÷PõÛ÷¯õ öáÛ]ì GßÓõÀ GßÚ?

3. Define the term bioenergetics.

£÷¯õGÚºöáiUì GߣuøÚ ÂÁ›.

4. What is substrate level phosphorylation? Give an example.

ÂøÚ£k ö£õ¸Ò AÍ»õÚ £õì£õ›÷»åß GßÓõÀ

GßÚ? J¸ Euõμn® u¸P.

5. What are Ketogenic amino acids? Give examples.

Rm÷hõöáÛU Aª÷Úõ Aª»[PÒ GßÓõÀ GßÚ?

Euõμn[PÒ u¸P.

Sub. Code 4BBC3C2

Page 6: A–8879 Sub. Code 4BBC3C1

A–8880

2

Wk ser6. Define transamination.

iμõß\õª÷Úåß Áøμ¯Ö.

7. Define the term –oxidation of fatty acids.

öPõʨ¦ Aª»[PÒ –BUêá÷ÚØÓ® GߣuøÚ

Áøμ¯Ö.

8. What are Ketone bodies?

Rm÷hõß £õjì GßÓõÀ GßÚ?

9. Compare nucleosides and nucleotide.

{²UÎ÷¯õø\k ©ØÖ® {²UÎ÷¯õøhk J¨¤kP.

10. What are purine bases?

¤²›U ÷£\ì GßÓõÀ GßÚ?

Part B (5 5 = 25)

Answer all questions, choosing either (a) or (b).

11. (a) Discuss in detail about glyoxalate cycle.

QøͯõP\÷»m _ÇØ] £ØÔ Â›ÁõP GÊxP.

Or

(b) What is glycogenesis? Explain it.

QøÍ÷PõöáÛ][ GßÓõÀ GßÚ? AuøÚ ÂÁ›.

12. (a) Give an elaborate note on high energy compounds.

AvP BØÓ¾øh¯ ÷\º©[PÒ £ØÔ Â›ÁõP GÊxP.

Or

(b) Explain the role of ATP/ADP cycle in transfer of high energy phosphate.

AvP BØÓ¾øh¯ £õì÷£m ©õØÓzvÀ H.j.¤/H.i.¤.

_ÇØ]°ß £[QøÚ ÂÁ›.

Page 7: A–8879 Sub. Code 4BBC3C1

A–8880

3

Wk ser13. (a) Discuss the metabolism of phenylalanine.

¤øÚÀ A»øÚÛß Áͺa]øu ©õØÓzvøÚ ÂÁ›.

Or

(b) Write briefly about the metabolism of leucine and lysine.

¼²]ß ©ØÖ® ø»]ß BQ¯ÁØÔß Áͺ]øu

©õØÓzvøÚ _¸UP©õP GÊxP.

14. (a) Write in detail about –oxidation of fatty acids.

öPõʨ¦ Aª»[PÎß –BUêá÷ÚØÓ® £ØÔ

›ÁõP GÊxP.

Or

(b) Describe the biosynthesis of triglycerides.

iøμQÎ\øμkPÎß EØ£zv¯õuÀ •øÓ°øÚ ÂÁ›.

15. (a) Explain the catabolism of purine nucleotides.

¤²›ß {²UÎ÷¯õøhkPÎß ]øu©õØÓzvøÚ ÂÁ›.

Or

(b) Discuss the catabolism of pyrimidine nucleotides.

¤›ªiß {²UÎ÷¯õøhkPÎß ]øu ©õØÓzvøÚ

ÂÁ›.

Part C (3 10 = 30)

Answer any three questions.

16. Explain the TCA cycle with its regulation.

TCA _ÇØ]°øÚ²® Pmk¨£õmk •øÓPøͲ® ÂÍUSP.

17. Discuss in detail about electron transport chain.

ªßÞmh ‰»UTÖPÒ ÷£õUSÁμzx G»Umμõß

iμõßì÷£õºm \[Q¼ £ØÔ Â›zx GÊxP.

Page 8: A–8879 Sub. Code 4BBC3C1

A–8880

4

Wk ser18. Give an elaborate note on metabolism of glycine, cysteine

and proline.

QøÍ]ß, ]ìjß ©ØÖ® ¦÷μõø»ß BQ¯ÁØÔß Áͺ]øu

©õØÓzvøÚ Â›ÁõP GÊxP.

19. Write an essay on cholesterol metabolism.

öPõ»ìiμõÀ Áͺ]øu ©õØÓzvøÚ¨ £ØÔ Pmkøμ GÊxP.

20. Describe the biosynthesis of purine nucleotides.

¤²›ß {²UÎ÷¯õøhkPÒ EØ£zv¯õuø» ÂÁ›.

————————

Page 9: A–8879 Sub. Code 4BBC3C1

wk 10

A–8881

B.Sc. DEGREE EXAMINATION, NOVEMBER 2019

Third Semester

Biochemistry

CELL BIOLOGY

(CBCS – 2014 onwards)

Time : 3 Hours Maximum : 75 Marks

Part A (10 2 = 20)

Answer all questions.

Write a note on :

1. Semi permeable membrane.

AøμU Phzv \ÆÄ.

2. Active transport.

ö\¯£õmk PhzuÀ.

3. Sucidal bag.

uØöPõø» ø£.

4. Power house.

BØÓÀ Ãk.

5. Centromere.

ö\ßm÷μõª¯º.

Sub. Code 4BBC3C3

Page 10: A–8879 Sub. Code 4BBC3C1

A–8881

2

Wk 106. Lambrush chromosome.

ÂÍUS y›øP S÷μõ÷©õ÷\õ®.

7. TCA cycle.

i.].H. _ÇØ].

8. M-phase.

G®–{ø».

9. Oncogene.

¦ØÖ ©μ£q.

10. Programmed cell death.

{ºn¯UP£mh ö\À CÓ¨¦.

Part B (5 5 = 25) Answer all questions.

11. (a) Write the characteristic differences between Eukaryote and prokaryote.

³÷P›÷¯õm ©ØÖ® ¦μ÷P›÷¯õmUPÎß £s¦PÎß

÷ÁÖ£õmøh GÊxP.

Or

(b) Write the proximate composition of the cell.

ö\À¼ß BØÓÀ u¸® ‰»UTÖPÒ Tmhø©¨ø£

GÊxP.

12. (a) Explain the structure and functions of ER.

C.Bº.(Gß÷hõ¤ÍõìªU öμmiS»®) –ß Aø©¨¦

©ØÖ® £oPøÍ ÂÍUSP.

Or

(b) Give a note on origin and functions of Lysosome.

ø»÷\õ÷\õªß EØ£zv ©ØÖ® £oPøͨ £ØÔ Jº

SÔ¨¦ GÊxP.

Page 11: A–8879 Sub. Code 4BBC3C1

A–8881

3

Wk 1013. (a) Write a note on human karyotype.

©Ûu S÷μõ÷©õ÷\õ®PÒ Aø©¨ø£ £ØÔ Jº SÔ¨¦

GÊxP.

Or

(b) What are the various types of DNA? Write a short note on it.

i.Gß.H UPÎß £À÷ÁÖ ÁøPPÒ ¯õøÁ? Jº ]Ö

SÔ¨¦ GÊxP.

14. (a) What is high energy molecule? Explain.

AvP BØÓÀ ‰»UTÖ ¯õøÁ? ÂÍUSP.

Or

(b) Explain the significance of meiotic divisions.

SßÓÀ ¤›Âß ]Ó¨¦ ußø©PøÍ ÂÍUSP.

15. (a) Give an account on characteristics of cancer cells.

¦ØÖaö\ÀPÎß ö£õx¨ £s¦PÒ £ØÔ Jº Pmkøμ

u¸P.

Or

(b) Write the characteristic features of oncogenes.

¦ØÖ ©μ£qUPÎß C¯À¦ £s¦PøÍ GÊxP.

Part C (3 10 = 30)

Answer any three questions.

16. Describe the fluid mosaic model structure of plasma membrane.

¨Íõì©õ \ÆÃß }º©{ø» ÷u©À ©õv› Aø©¨ø£ ÂÁ›.

Page 12: A–8879 Sub. Code 4BBC3C1

A–8881

4

Wk 1017. Explain the structure and functions of mitochondria.

ø©m÷hõPõßi›¯õÂß Aø©¨¦ ©ØÖ® £oPøÍ ÂÍUSP.

18. Give a detailed account on DNA replication.

i.Gß.H Âß Cμmi¨£õuÀ £ØÔ Jº ›ÁõÚ Pmkøμ u¸P.

19. Describe the Krebs cycle.

QμL¨ì _ÇØ] ÂÁ›UP.

20. Discuss the types and properties of cancer cells.

¦ØÖ ö\ÀPÎß ÁøPPÒ ©ØÖ® ö£õx¨ £s¦PøÍ ÂÁõv.

——————

Page 13: A–8879 Sub. Code 4BBC3C1

WK11

A–8884

B.Sc. DEGREE EXAMINATION, NOVEMBER 2019

Fourth Semester

Bio-Chemistry

Elective — BIOTECHNOLOGY

(CBCS – 2014 onwards)

Time : 3 Hours Maximum : 75 Marks

Part A (10 2 = 20)

Answer all questions.

1. EcoRI

EcoRI

2. BAC

BAC

3. cDNA

c i.Gß.H

4. Tag sequences

÷hU Á›ø\PÒ

5. Biolistics

£÷¯õ¼ìiUì

6. Liposomes

¼¨÷£õ÷\õ®PÒ

Sub. Code 4BBCE1A

Page 14: A–8879 Sub. Code 4BBC3C1

A–8884

2

WK117. CDFD

].i.G¨.i

8. Lowry method

»¨› •øÓ

9. Flavr Savr

÷£»Áº ÷\Áº

10. Terminator gene.

öPõÀ¾® ãßPÒ.

Part B (5 5 = 25)

Answer all questions, choosing either (a) or (b).

11. (a) Discuss the types of plasmids.

¤Íõìªm ÁøPPøÍ ÂÁõv.

Or

(b) Enumerate the enzymes involved in cloning.

S÷ÍõÛ[QÀ £¯ß£k® ö|õvPÒ £ØÔ £mi¯¼k.

12. (a) Explain RFLP and its uses.

Bº. G¨.GÀ.¤ ÂÁ›zx £¯ßPøÍ ÂÁ›.

Or

(b) Write the steps involved in the synthesis of cDNA.

c.i.Gß.H Âøn E¸ÁõUS® •øÓ°øÚ GÊx.

Page 15: A–8879 Sub. Code 4BBC3C1

A–8884

3

WK1113. (a) Describe the microinjection technique.

~sF] ~m£ •øÓ°øÚ ÂÁ›.

Or

(b) Discuss the process of viral transfection process.

øÁμì ‰»® áús Phzx® •øÓ°øÚ ÂÁõv.

14. (a) Briefly explain quantitative analysis of nucleic acids.

{²UÎU Aª»zvøÚ AÍÂøÚ PnUQk®

•øÓ°øÚ ÂÁ›.

Or

(b) What is RAPD? Enlist its applications.

Bº.H.¤.i GßÓõÀ GßÚ? Auß £¯ßPøÍ £mi¯¼k.

15. (a) Give an account of recombinant blood products.

©ÖCønÄ Cμzu ö£õ¸mPøÍ £ØÔ öuõS¨¦ u¸P.

Or

(b) Briefly explain on advantages of transgenic animals production.

áúß ©õØÓ©øh¢u »[SPÒ E¸ÁõUPzvß

£¯ßPøÍ _¸UP©õP ÂÍUS.

Part C (3 10 = 30)

Answer any three questions.

16. Give a detailed account on artificial chromosomes.

ö\¯ØøP S÷μõ÷©õ÷\õ®PøÍ £ØÔ öuõS¨¦ u¸P.

17. Describe the DNA sequencing methods.

i.Gß.H. Á›ø\PøÍ PshÔ²® •øÓPøÍ ÂÁ›.

Page 16: A–8879 Sub. Code 4BBC3C1

A–8884

4

WK1118. Explain the Ti plasmid mediated gene transformation.

Ti ¤Íõìªm ‰»® áúß ©õØÓ® £ØÔ ÂÁ›.

19. Write an essay on DNA finger printing technique.

i.Gß.H ÂμÀ uh¯Â¯À •øÓ°øÚ £ØÔ Pmkøμ GÊx.

20. Give a detailed account on production of transgenic food products.

áúß ©õØÓ EnĨ ö£õ¸mPÎß EØ£zv £ØÔ öuõS¨¦

u¸P.

————————

Page 17: A–8879 Sub. Code 4BBC3C1

wk 10

A–8885

B.Sc. DEGREE EXAMINATION, NOVEMBER 2019

Fifth Semester

Biochemistry

MOLECULAR BIOLOGY

(CBCS – 2014 onwards)

Time : 3 Hours Maximum : 75 Marks

Part A (10 2 = 20)

Answer all questions.

1. Z-DNA

Z-DNA.

2. Transformation.

iμõß죺÷©åß.

3. Okazaki fragment.

JPõ\Q xPÒPÒ.

4. Helicase.

öí¼÷Pì.

5. Shine-Dalgarno sequence.

øíß–hÀPº÷Úõ Á›ø\.

6. Holenzyme.

÷í»õ Gßø\®.

Sub. Code 4BBC5C1

Page 18: A–8879 Sub. Code 4BBC3C1

A–8885

2

Wk 107. Wobble hypothesis.

Ĩ¤À ÷Põm£õk.

8. Methylation.

ö©v÷»åß.

9. SOS repair.

SOS \› ö\´uÀ.

10. Inducible operon.

ysh¨£k® J£μõß.

Part B (5 5 = 25)

Answer all questions.

11. (a) Write the different forms of DNA.

i.Gß.H Âß ÁøPPøÍ GÊx.

Or

(b) Describe the importance of repetitive DNA sequence and satellite DNA.

öuõhº¢x Á¸® i.Gß.H. Á›ø\ ©ØÖ® \õmiø»m

i.Gß.Âß •UQ¯zxÁzøu ÂÁ›.

12. (a) Enlist the types of DNA replication.

i.Gß. Cμmizu¼ß ÁøPPøÍ £mi¯¼kP.

Or

(b) Discuss the enzyme involved in DNA replication.

i.Gß.H Cμmizu¼À Dk£k® ö|õvPøÍ ÂÁõv.

Page 19: A–8879 Sub. Code 4BBC3C1

A–8885

3

Wk 1013. (a) Write the inhibitors of transcription.

iμõßìQ›¨åß uøh PõμoPøÍ GÊx.

Or

(b) Discuss the factors involved in transcription.

£iö¯kzu¼À Dk£k® PõμoPøÍ ÂÁõv.

14. (a) Describe the types of ribosomes.

øμ÷£õ÷\õ®PÎß ÁøPPøÍ ÂÁ›.

Or

(b) Write the types of post translational modification.

¤ß ö©õÈö£¯ºzuvÀ ©õØÓ[PÎß ÁøPPøÍ GÊx.

15. (a) Write a short account on types of mutation.

wjº ©õØÓ ÁøPPøÍ £ØÔ ]Ö SÔ¨¦ GÊx.

Or

(b) Explain the DNA repair mechanism.

i.Gß.H \›ö\´uÀ •øÓ°øÚ ÂÍUSP.

Part C (3 10 = 30)

Answer any three questions.

16. Discuss the types of DNA.

Bº.Gß.H Âß ÁøPPøÍ ÂÁõv.

17. Describe DNA replication process in prokaryotes.

¦÷μõ÷P›÷¯õiÀ Põn¨£k® i.Gß.H Cμmizuø» ÂÁ›.

18. Discuss the process of prokaryotic transcription.

¦÷μõ÷P›÷¯õmiß £iö¯kzuø» ÂÁõv.

Page 20: A–8879 Sub. Code 4BBC3C1

A–8885

4

Wk 1019. Describe the process of eukaryote translation.

²÷P›÷¯õm ö©õÈö£¯ºzuø» ÂÁ›.

20. Elaborately discuss the tryptophan operon concept.

i›¨h÷£õß J£μõß ÷Põm£õk £ØÔ Â›ÁõP ÂÁõv.

——————

Page 21: A–8879 Sub. Code 4BBC3C1

Ws9

A–8886

B.Sc. DEGREE EXAMINATION, NOVEMBER 2019

Fifth Semester

Biochemistry

CLINICAL BIOCHEMISTRY

(CBCS – 2014 onwards)

Time : 3 Hours Maximum : 75 Marks

Part A (10 2 = 20)

Answer ALL questions.

1. Renal threshold.

ŸÚº öuõhUP {ø» AÍÄ

2. Glycosuria

QøÍU÷Põ`›¯õ

3. Tay Sachs disease

÷h–\õa ÷|õ´

4. Gaucher's disease

Põ´a\º ÷|õ´

5. Urecemia

³›]ª¯õ

6. Proteinuria

¦÷μõmiÝ›¯õ

Sub. Code 4BBC5C2

Page 22: A–8879 Sub. Code 4BBC3C1

A–8886

2

Ws9

7. Xanthinuria

\õ¢øuÝ›¯õ

8. Orotic aciduria

K÷μõiU Aª» ]Ö}º.

9. Rheumatoid Arthritis

•hUSÁõu RÀÁõu®

10. Allergents

KÆÁõø© PõμoPÒ.

Part B (5 5 = 25)

Answer all questions, choosing either (a) or (b).

11. (a) Write note on GTT.

GTT £ØÔ ÂÁ›.

Or

(b) Explain on Hyperglycemia.

øí£ºQøÍ^ª¯õÂøÚ ÂÁ›.

12. (a) Explain the types of Hyperlipoproteinemias.

E¯º öPõʨ¦ ¦μu[PøÍ ÁøPPÐhß ÂÁ›.

Or

(b) Write note on Fabry's disease.

£õ¨›ì ÷|õ´ £ØÔ GÊxP.

13. (a) Discuss the Homocystenuria.

÷í÷©õ]ìiÝ›¯õ £ØÔ ÂÁõv.

Or

Page 23: A–8879 Sub. Code 4BBC3C1

A–8886

3

Ws9

(b) Give an account on inborn errors of amino acid metabolism.

Aª÷Úõ Aª» Áͺ]øu ©õØÓzvß SøÓ£õkPÐhß

¤Ó¢u SÇ¢øu¨ £ØÔ J¸ Pmkøμ u¸P.

14. (a) Explain the Adenosyl phospho ribosyl transferase deficiency.

Ai÷Úõ]À £õì÷£õ ›÷£õêÀ iμõßì£÷μì

SøÓ£õk £ØÔ ÂÁ›.

Or

(b) Explain on Lesch-Nyhan syndrome.

½a ø|Pß SøÓ£õk £ØÔ ÂÁ›.

15. (a) Explain the causes of Allergy.

KÆÁõ©¯õÀ HØ£kÁÚÁØøÓ ÂÁ›.

Or

(b) Explain the types of Allergy.

JÆÁõ©°ß ÁøPPøÍ ÂÁ›.

Part C (3 10 = 30)

Answer any three questions.

16. Classify the diabetes mellitus in detail.

\ºUPøμ ÷|õø¯ ›ÁõP ÁøP¨£kzxP.

17. Explain the inborn errors of lipid metabolism.

öPõʨ¦PÎß Áͺ]øu ©õØÓzvÀ Ehß ¤Ó¢u

SøÓ£õkPøÍ ÂÁ›.

18. Discuss the porphyrias in detail.

£õºø£›¯õøÁ ›ÁõP ÂÁ›.

Page 24: A–8879 Sub. Code 4BBC3C1

A–8886

4

Ws9

19. Give a detail account on Gout

öPÍmiøÚ Â›ÁõP ÂÁ›.

20. Explain the types of hypersensitivity in detail

Av EnºvÓøÚ ÁøPPÐhß Â›ÁõP ÂÍUSP.

————————

Page 25: A–8879 Sub. Code 4BBC3C1

Ws17

A–8887

B.Sc. DEGREE EXAMINATION, NOVEMBER 2019

Fifth Semester

Biochemistry

Elective– MICROBIOLOGY AND IMMUNOLOGY

(CBCS – 2014 onwards)

Time : 3 Hours Maximum : 75 Marks

Part A (10 2 = 20)

Answer all questions.

1. Virion

›¯õß

2. Evkaryota

³÷P›÷¯õmhõ

3. Autotrphs

_¯ ãÂ

4. Log Phase

»õU {ø»

5. Botulism

ö£õmk¼\®

6. Proteolytic bacteria

¦μmi÷¯õø»iU £õUj›¯õ

Sub. Code 4BBCE2A

Page 26: A–8879 Sub. Code 4BBC3C1

A–8887

2

Ws 17

7. NK cells.

Gß.÷P.ö\ÀPÒ

8. Hapten

öP¨hß

9. Allergy

JÆÁõø©

10. Auto graft

_¯ Jmk

Part B (5 5 = 25)

Answer all questions.

11. (a) Write the structural organisation of virus.

øÁμêß J¸[Qøn¢u Aø©¨¤øÚ GÊxP.

Or

(b) How do you identity the gram positive and gram negative bacteria? Explain.

Qμõ® ÷|º•øÚ ©ØÖ® Gvº •øÚ £õUj›¯õUPøÍ

GÆÁõÖ } PshÔÁõ´? ÂÍUSP.

12. (a) What are the different types of nutrition? Explain.

£À÷ÁÖ ÁøP EnÅmh[PÒ ¯õøÁ? ÂÍUSP.

Or

(b) Write the different methods of bacterial reproduction .

£À÷ÁÖ ÁøP¯õÚ £õUj›¯õ CÚ¨ö£¸UP •øÓø¯

GÊxP.

Page 27: A–8879 Sub. Code 4BBC3C1

A–8887

3

Ws 17

13. (a) How food are in become to poison? Explain

EnÄ GÆÁõÖ Âå©õP ©õÖQÖx? ÂÍUSP.

Or

(b) Give an account on fermentation on milk products.

ö|õvzuÀ ‰»® QøhUS® £À÷ÁÖ £õÀ

ö£õ¸mPøͨ £ØÔ Kº Pmkøμ u¸P.

14. (a) What are the cells of the immune system? Explain.

÷|õ´ Gvº¨¦ ©sh»zvß £À÷ÁÖ ÁøP ö\ÀPÒ

¯õøÁ? ÂÍUSP.

Or

(b) Give an account the types of immuno diagnostic methods

£» ÁøP ÷|õ´ Gvº¨¦ ©sh» £›÷\õuøÚ

•øÓPøͨ £ØÔ Kº Pmkøμ u¸P.

15. (a) Differentiate classical and alternate pathways.

]Ó¢u ©ØÖ® ©õØÖ ÁÈ ÷|õ´ Gvº¨¦ £õøuPøÍ

÷ÁÖ£kzv PõsP.

Or

(b) What are immuno suppressive agents? Explain.

÷|õ´ Gvº¨¦ ußø© SøÓ¨¦ PõμoPÒ ¯õøÁ?

ÂÍUSP.

Part C (3 10 = 30)

Answer any three questions.

16. Give an account on occurrence and economic importance of yeasts.

Dìmiß ö£õ¸Íõuõμ •UQ¯zxÁ® ©ØÖ®

QøhUP¨ö£ÖuÀ £ØÔ Kº Pmkøμ u¸P.

Page 28: A–8879 Sub. Code 4BBC3C1

A–8887

4

Ws 17

17. Explain the conjugation mode of bacterial reproduction.

£õUj›¯õÂß CøÚÄ •øÓ CÚ¨ö£¸UP® £ØÔ ÂÍUSP.

18. How microbes are used in industries for various application? Explain

£À÷ÁÖ ÁøP £¯ß£õmiØUS, ~ßq°ºPÒ GÆÁõÖ

öuõÈØ\õø»PÎÀ £¯ß£kzu¨£kQßÓÚ? ÂÍUSP.

19. Describe the structure of immunoglobulin ‘G’.

÷|õ´ Gvº¦μu® (C®²÷ÍõS÷Íõ¦¼ß) â–ß Aø©¨¤øÚ

ÂÁ›.

20. Write in detail on the mechanism of graft rejection and tissue typing.

Jmk »USuÀ ©ØÖ® v_ ÁøPPÎÀ ~m£ ö\¯ø» ›ÁõP

GÊxP.

————————