A reason to do IT Running IT Running IT for a Global Biotech Company for a Global Biotech Company Roberto Tolini Roberto Tolini Manager Corporate Engineering Manager Corporate Engineering CERN 05Jul2005 CERN 05Jul2005
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A reason to do IT
Running ITRunning ITfor a Global Biotech Companyfor a Global Biotech Company
Roberto ToliniRoberto ToliniManager Corporate EngineeringManager Corporate Engineering
CERN 05Jul2005CERN 05Jul2005
A reason to do IT
Our Industry
Our Company
Our IT Function
Our IT infrastructure
AgendaAgenda
A reason to do IT
• Demographics - Aging population in industrialized countries and associated healthcare needs are growing
• A significant number of important medical needs remain unmet and a new set of diseases are emerging
• New technologies are accelerating the discovery process and could facilitate the discovery of new therapeutic agents
• The rapid evolution of medical practices and novel clinical approaches to address healthcare issues will lead to new opportunities (efficacy, safety, convenience, and pharmaeconomics)
The Biotech IndustryThe Biotech Industry
A reason to do IT
• Biotech has delivered on its promises:
- over 100 compounds now approved
- several blockbusters
• Biotech R&D will continue to be productive:
- Approximately 500 biotech compounds in development
- A significant number of pending regulatory filings
- Many major new drug approvals and launches expected
• Biotechnology is no longer a niche. Big Pharma is coming!
10
3
3
28
7
10
2
16
16
7
1
113
6
2
47
15
4
10
178
3
26
21
0 20 40 60
Other
Infertility
Heart diseases
Diabetes
Blooddisorders
AIDS/HIVIn Development
Approved
Biopharmaceutical Benchmarks
Source: Walsh G., Nature Biotechnology, Vol. 21, 8, Aug. 2003, p.867
The Biotech IndustryThe Biotech Industry
A reason to do IT
Our Industry
Our Company
Our IT Function
Our IT infrastructure
AgendaAgenda
A reason to do ITSerono ProfileSerono Profile
Who we are:Who we are:
• Fully integrated global biotech company (R&D, Mfg, M&S) with almost 100 years of history in biologic therapies
operate in 45 countries
sales in over 100 countries
4,600 employees worldwide
6 recombinant products on the world market
revenues of $2.3 billions in 2004
• Largest biotech company in Europe
• Third largest biotech company worldwide
• Platform of new technologies
A reason to do ITA Global Biotech LeaderA Global Biotech Leader
3rd Biotech worldwide, 1st biotech outside USA3rd Biotech worldwide, 1st biotech outside USA
29%
45%
40%
63%
10%
47%
81%
65%
Lead Product as % of Revenues
2003 Reported Revenues
868
1'054
1'580
1'752
1'852
3'300
2'019
8'356
Gilead
Medimmune
Genzyme
Chiron
Biogen IDEC
Serono
Genentech
Amgen
A reason to do IT
Reproductive Health
Neurology: Multiple Sclerosis
Growth and MetabolismDermatology: Psoriasis
Our ProductsOur Products
A reason to do ITOur types of proteinsOur types of proteins
Human hormones (messages between organs)
Human cytokines (messages between cells)
Molecules which influence hormones and cytokines
LIF
Anastrozole
IL18-BP Onercept TBP-1
A reason to do IT
Our Industry
Our Company
Our IT Function
Our IT infrastructure
AgendaAgenda
A reason to do IT
ApplicationApplicationHosting ServicesHosting Services
Voice & DataVoice & DataTelecom ServicesTelecom Services
IT ResearchIT Research& Development& Development
IT CustomerIT CustomerValue DeliveryValue Delivery
GovernanceGovernance
Organisation StructureOrganisation StructureWe concentrate our forces
on five global strategic units
A reason to do ITOrganisation StructureOrganisation Structure
We created and managethree main regions
USAServices25% staff
HQServices50% staff
AffiliatesServices25% staff
A reason to do IT
We are a global organisation of 140 employees supporting
4’600 users in more than 60 locations and from 30 different countries in the world.
Global PresenceGlobal Presence
North America
Argentina Brazil Uruguay Venezuela Colombia Mexico
Latin America
Australia New-Zealand
Japan
Europe, Middle-East, Africa
Asia-Pacific
Oceania
Singapore Korea Hong-Kong Taiwan Thailand China
Switzerland France UK Germany Austria Netherlands
Sweden Danemark Finland Norway Czech Rep. Slovakia
Poland Lithuania Russia Croatia Italy Spain
Canada USA Puerto Rico
Portugal Greece Israel South Africa Egypt Tunisia
Algeria Morocco Turkey Jordan Saudi Arabia United Arab Em.
A reason to do IT
Our Industry
Our Company
Our IT Function
Our IT infrastructure
AgendaAgenda
A reason to do ITOverall pictureOverall picture
• 2 main DataCenters: Geneva and Boston2 main DataCenters: Geneva and Boston
A mirror site has been created in Boston to maintain business
continuity in case of major disaster
• Consolidation and centralization of all business Consolidation and centralization of all business applicationsapplications
Over the past 7 years, we have built a highly
centralized IT environment.
All subsidiaries of the Group access their enterprise application resources remotely in our headquarters.
• WW local sitesWW local sites
Telecom is playing a critical role in allowing WW sites to run
business.
A reason to do ITIT environment overall pictureIT environment overall picture
Production Network
Novell ServersIntel
Domino ServersAS/400
Oracle ServersAIX
Documentum dataOracle data(Production)
Domino data
Novell data
Documentum ServersAIX/Solaris
"Other" data sources (clinical
studies, trials, etc…), test and development
(Oracle, etc…)
Other Servers
Dedicated Storage IBM ESS800 HDS 9570V IBM ESS800
Various Storage(HDS9580V and DAS)
• Heterogeneous environments (AIX, Solaris, Windows, Linux, Novell Netware, etc…)• Heterogeneous applications (ERP, Documentum, File Servers, Clinical, etc…) and storage (IBM ESS, HDS95xx and Centera)
A reason to do ITSome StatisticsSome Statistics
3’000 Desktops3’000 Desktops1’500 Laptops1’500 Laptops
20M20Me-mails/yeare-mails/year
35’00035’000calls/yearcalls/year
1’5001’500cyber-attacks/yearcyber-attacks/year
400 Servers400 Servers
500500ApplicationsApplications
60 Terabytes60 Terabytesof Dataof Data
120 Telecom 120 Telecom LinesLines
100100New projectsNew projects
per yearper year
A reason to do ITFactsFacts
What we have today:
• 400 servers in Datacenters
• > 10 storage systems WW (EMC2, HDS and IBM)
• 1 IBM3494 library and 1 disk library (HQ)
• 1 tape library in Boston
• 2 backup copies AND offsite archiving
• Daily backup amount: 500GB HQ and 100GB Boston
• Total data on library: around 42TB (HQ)
• Total offsite tapes: over 6000
And we are still growing…
A reason to do ITMain challengesMain challenges
Availability vs processing powerAvailability vs processing power
• We need to ensure application availability 24/7• Minimize downtime (SLA engagment)• Provide appropriate service levels per application type
Data growingData growing
• Storage space increase• Backup window shrinking• Performances• Long-term archiving (business and legal requirements)
Data accessibilityData accessibility
• Data availability in a reasonable time• Telecom connections WW cost and peformances• Restore time and reliability• Long-term archiving technology AND accessibility
A reason to do IT
• Biotech market is rapidly expanding and full of challenges and oppurtunities
• Serono has a broad portfolio of products but it’s still investing in new therapeutic areas
• IT @ Serono has both the challenge to run business-related application and scientific application
• Our goal is to provide a scalable and flexible architecture able to fullfill technological and business requirements
• Today’s main challenges in the Business area are main about application availability and data growth rather than processing power.
SummarySummary
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