A. R. Life Sciences Private Limited, Hyderabad, Pharmaceutical Intermediates

A.R. LIFE SCIENCES PVT LTD

A.R. Life Sciences Pvt Ltd

BACKGROUND

n  Established in 1996… as Calcium Chloride manufacturer n  Shifted to Manufacturing Intermediates for APIs in 2004 n  Unit-1: located in Jeedimetla, Hyderabad

q  Mainly into Intermediates manufacturing

n  Unit-2: Located in Pharma City, Parawada, Visakhapatnam q  Manufacture both intermediates and APIs q  Modern unit built as per USFDA guidelines

n  Revenue in 2011-12: Rs 100 crores (USD 20 Million) n  Major portion of business through contract manufacturing

in both our units


Quality

n  Committed to Quality products and systems at both our units n  Dedicated Quality assurance team to make sure products are

manufactured according to current GMP guidelines n  ISO Certification for unit-1 and GMP certification for unit-2

available n  Quality control department equipped with instruments like HPLC,

and GC n  All procedures including

q  Change control q  Equipment qualification and calibration q  Process validation q  Deviation handling q  Customer complaint handling

n  GMP trainings conducted for time to time A.R. Life Sciences Pvt Ltd

Reaction Strengths

n  Grignard Reaction n  Hydrogenation n  Alkylation n  Halogenation n  Hoffmann Reaction n  Oxidations n  Reductions n  Condensation n  Chlorination n  Dehydrogenation n  Allylic Bromination


Infrastructure


Unit-1 Unit-2

Production Blocks 2 (including 1 for Hydrogenation)

3 (including one for hydrogenation and one under construction)

Reaction Capacity 30 m3 60 m3 (Will increase upto 100 m3 once third prod block is ready)

Min/Max size of reactors 250L/3000L 500L/4000L

GLR/SSR 5/15 7/16 (excluding reactors in new prod block)

Reaction capability Temp: -20 to 125 Deg C Pressure upto 15 kg/cm2

Temp: -20 to 125 Deg C Pressure upto 15 kg/cm2 (Liquid nitrogen provision provided to go upto -70 Deg C reactions)

Type of products Intermediates only Intermediates and Drugs

Clean Room Class 100000

Infrastructure (QC)


Unit-1 Unit-2 HPLC 2 3 GC 2 2 Other items like UV, Potentiometer, MR, KF, pH/TDS, Muffle furnace, Oven

Available Available

Additional items Stability Chambers, MilliQ water system

R & D (Central)

n  New product development lab at Unit-1 n  Have a dedicated team (12) of Qualified and

experienced people n  R&D head has experience of over 15 years in new

intermediates and API development n  Activities

q  New product development q  Process developments and cost improvements q  Identification and synthesis of impurities q  Scale up of products from grams to kilograms

n  Each units has independent process development lab


Unit-1 Photos


Unit-1 Photos (R&D)


Unit-2 Photos


Unit-2 Photos


Unit-2 Photos


Unit-2 Photos (Cleanroom)


THANK YOU

A.R. Life Sciences Pvt. Ltd. Office: H.No. 8-3-222/1/5, Behind Allahabad Bank, Madhuranagar,

Yousufguda Road, Hyderabad - 500 038. Unit-I : Unit-II Plot No. 338, Plot No. 34-C.J.N. Pharmacity, S.V. Co-operative Industrial Estate, Parawada (Village & Mandal), Jeedimetla, Hyderabad - 500 055. Visakhapatnam-531 021. A.P. India A.P. India.

Email to [email protected] for any information


A. R. Life Sciences Private Limited, Hyderabad, Pharmaceutical Intermediates

Business