6 ranieri dupont - biofuels - GBEP · WIREC March 05, 2008 John Ranieri Vice President-General Manager DuPont Applied BioSciences Biofuels

WIREC

March 05, 2008

John RanieriVice President-General Manager

DuPont Applied BioSciences

Biofuels

© 2007 E.I. du Pont de Nemours and Company. All Rights Reserved.

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DuPont Applied BioSciences Strategy

Focus on large, market driven opportunities enabled by the

integration of chemistry and biology . . .

• Target areas with existing and emerging unmet needs

where our integrated science creates unique advantage

• Transform the targeted industries with our integrated

knowledge base

• Partnerships to expand market opportunities, accelerate

speed to market and maximize value creation

© 2007 E.I. du Pont de Nemours and Company. All Rights Reserved.

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Ethanol

Advanced Biofuels

Cellulose

Starch

Sugar

Seed

Crop Protection

CO2

Plant

Feedstocks

Biofuels

Formulation

Fermentation

Processes

Agricultural

Inputs

Conversion to

Sugars

Biofuels Value Chain

Biofuels

© 2007 E.I. du Pont de Nemours and Company. All Rights Reserved.

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We can engineer a cell to

economically produce high

value products

Cell

Factory

Metabolic Engineering

Cell software has been

re-programmed to increase propanediol

production by 500 fold

Genome

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c

Chemical Process

CH2=CHCH3

Propylene

HOCH2CH2CH2OH

PDO

Bioprocess

C6H12O6

Glucose

Targeted advantages over chemical process

~25% Lower manufacture cost

~50% Lower capital

~50% Smaller environmental footprint

HOCH2CH2CH2OH

Bio-PDO™

Catalyst Biocatalyst

Why a Bioprocess?

© 2007 E.I. du Pont de Nemours and Company. All Rights Reserved.

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DuPont Tate & Lyle Bio ProductsLoudon, Tenn., USA

© 2007 E.I. du Pont de Nemours and Company. All Rights Reserved.

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Biofuel Imperatives

Current biofuel solutions are inadequate to meet global needs

Feedstock

Adequate Regional Supply

Refinery & Pipeline

Compatibility With Existing

Infrastructure

Retail & Consumer

Uncompromised Fuel Performance

Upstream Downstream

High value molecules

© 2007 E.I. du Pont de Nemours and Company. All Rights Reserved.

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Sugar Fermentation

Metabolic

Engineering

BIOMASS

BUTANOL

WORLDWIDE FUEL MARKETS

DuPont - BP PartnershipResolving Ethanol Constraints

Plant

Feedstocks

Performance

Fuels

Butanol

© 2007 E.I. du Pont de Nemours and Company. All Rights Reserved.

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�Corn cob & stover �Sugarcane bagasse

�Wheat straw

�Rice straw

�Energy crops

Cellulosic BiofuelsConcept to Commercialization

CellulosicBiofuelsSugarBiomass

Raw MaterialBiomass

ProcessingFermentation

• Technology Development• Pilot Facility

• Commercial• License Technology Broadly

�Proprietary

conversion

microbes

�C5

�C6

�Ethanol

�Butanol �Saccarification

DuPont Integrated Corn-Based BioRefinery

© 2007 E.I. du Pont de Nemours and Company. All Rights Reserved.

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FuelsMaterials - Chemicals

FeedstockProduction

FeedstockHarvest

FeedstockConversionFeedstock

TransportFermentationProduction

Blending

Separation

Value Chain Partnerships

© 2007 E.I. du Pont de Nemours and Company. All Rights Reserved.

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Summary

� Integrated science approaches are necessary

� Technical feasibility

� Environmental sustainability

� Partnerships are essential

� Technology is complex

� Governmental support is required (at this point)

� High risk/high investment

� Value externalities

� Geography specific strategy

� Regions will require customized solutions