5th International and 17th Iranian Congress of Nuclear Medicineup.bme711.ir/up/bme711/Documents/ICNM_2013_Program_Book_(w… · 5th International and 17th Iranian Congress of Nuclear

5th International and 17th Iranian Congress of Nuclear Medicine

Presidents: Prof. M.H. Imanieh

Prof. K. Vesal

Mehrossadat Alavi,MDChair, scientific committee

Mahdi Haghighatafshar,MDGeneral Secretary Mohammad Entezarmahdi,

PhD candidatechair, executive committee

With Special Thanks to: • Dr. Reza Faghihi• Dr. Sedigheh Sina• Ms Banafsheh Zeinali Rafsanjani, PhD candidate• Dr. Hossein Sadeghpoor• Alireza Tootoonchi, the IT Coordinator• Mrs Nazanin Kamyab, Mrs. Fatemeh Masoodi, the congress secretariat

And Also:• Staff of Nuclear Medicine Department, Namazi Hospital• Radiation Research Center of Shiraz University• Nuclear Engineering Department of Shiraz UniversityAnd • The Shiraz University of Medical Sciences Chancellor and vice-Chancellor• The Shiraz School of pharmacy

Dr.Mehrossadat Alavi (Chair, scientific committee)

• Clinical Nuclear medicineDr.Mohsen SaghariDr.Arsalan VakiliDr.Mohammad EftekhariDr.S.Rasoul ZakaviDr.Isa NeshandarDr.Jamshid FarahatiDr.Hojjat AhmadzadehfarDr.Halluck.B SaymanDr.Dirk RoggenbukDr.Mohsen BeheshtiDr.Babak FallahiDr.S.Hasan FirouzabadiDr.Fereydoun FotuhiDr.Nahid YaghoubiDr.Ramin SadeghiDr.Vahid Reza Dabagh kakhakiDr.Babak Shafiei

Dr.Majid AsadiDr.Said FarzanehfarDr.Mehrangiz AmiriDr.Shahram SeifollahiDr.Maryam HamidianDr.Elaheh PirayeshDr.Esmail GharapapaghDr.Asghar KhancherliDr.Mojtaba Ansari

• Radiobiology Group:Dr. Mohamad Javad Mortazavi (Head of radiobiology group)Dr. Ali Shabestani MonfaredDr. Seyed Rabie MahdaviDr. Alireza ShiraziDr. Hamid Reza KhosraviDr. Hossein MozdaraniDr. Mehdi SohrabiMrs. Simin Mehdizadeh

• Physics group:Dr. Mohammad Reza Ay (Head of physics group)Dr. Hossien RajabiDr. Reza Faghihi Dr. Abbas Takavar Dr. Pardis Ghafarian Dr. Peter Knoll Dr. Mahmood Reza AghamiriDr. Mehdi Momennezhad

• Radiopharmacy group : Dr. Davood Beiki (Head of radiopharmacy group)Dr. Amir Reza Jalilian Dr.Soraya ShahhosseiniDr.Seyed Jalal Hosseinimehr Dr.Keyvan SadriDr.Hossein SadeghpourDr. Alireza DoroudiDr. Mostafa Erfani

Scientificcommittee

8:00 – 9:00 Opening ceremony

9:00 - 10:30 Session 1Chairs M.Saghari/ K.Vesal /S.H. FiroozabadiCME 1: Nuclear cardiology 9:00 - 9:25 SPECT MPI Attenuation/scatter/ Resolution: artifacts and correction Peter Knoll9:25 - 9:40 Prognostic implication of MPI stress SPECT Babak Shafiee9:40 - 10:00 Prognostic predictions in patients with abnormal MPI and angiographic InsignificantCAD Nahid Yaghoobi10:00 - 10:20 Comparison of non-invasive techniques for MPI Shahram Seyfollahi10:20 - 10:30 Q&A

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10:30 - 11:00 Break

11:00 -12:30 Session 2Chairs M.Eftekhari /V.Dabbagh/M.AsadiClinical investigation and research work: Nuclear cardiology 11:00 - 11:15 An outline of cardiovascular molecular imaging Majid Asadi11:15 - 11:30 AssessmentofdiastolicleftventriculardysfunctionafterDipyridamole stress on gated myocardial perfusion SPECT Mohammad Ali Qodsi Rad/Vahid Reza Dabbagh

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11:30-11:40 ComparingthediagnosticsensitivityandspecifityofTc-99m MIBISPECTinfivedefiniteprotocolsforscreeningofCAD Mahdi Haghighatafshar

11:40-11:50 A NewMethodforrapidLabelingofMIBIwithTechnetium99m. Seyyed Mostafa Saadati11:50-12:00 ValueofDipyridamole-InducedLeftBundleBranchBlock Mortaza Bostani

12:00-12:15 progress in Nuclear Medicine imaging Bela Kari

12:30 – 13:30 Case discussion 1: nuclear cardiology Babak Fallahi

13:30 – 14:30 Lunch (Sponsered by Shiraz Central Hospital)

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14:30-16:00 Session 3Chairs Sh.Dabiri/H.Ahmadzadehfar/ M.Amouei CME 2:Nuclear Medicine and Treatment14:30 – 14:50 Radiopharmaceuticals in Iran-Current & research radiotracers-new trends Amirreza Jalilian14:50 – 15:10 An overview of theranostics Majid Asadi15:10 – 15:30 Radioguided surgery Elaheh Pirayesh15:30 – 15:50 Management of dementia by PET Hojjat Ahmadzadehfar 15:50 – 16:00 Q&A16:00 – 16:30 Break16:30 – 17:30 Workshop 1:Quantitative MPI Vahidreza Dabbagh

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8:15-10:30 Session 4Chairs A.vakili/I.Neshandar/M.Beheshti /R.SadeghiCME3: Nuclear oncology 8:15 – 8:30 Update on oncologic radiopharmaceuticals Soraya Shahhosseini8:30 – 8:50 Tumor marker guided PET in breast cancer recurrence Borzu Rashidi8:50 – 9:10 Neuroendocrine tumors Mohsen Beheshti9:10 – 9:30 Treatment of Neuroendocrine tumors Halluk B. Sayman9:30-9:45 Sentinel node mapping in endometrial cancer patients using cervical injection of radiotracer and blue dye: single center 4 year experience Ramin Sadeghi

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9:45 - 10:00 Predictors of bone metastasis in pre-treatment staging of asymptomatic treatment- naïve patients with prostate cancer Masoud Moslehi10:00 - 10:15 Accuracy of sentinel node biopsy in staging of non-small cell lung carcinomas:systematicreviewandmeta-analysisoftheliterature. Susan Shafiei/Ramin Sadeghi

10:15 - 10:30 Q&A

10:30 - 11:00 Break

11:00 - 12:30 Session 5Chairs F.Fotuhi /M.Ansari/N.YaghoobiClinical investigation and researchWorks(2):Endocrine system 11:00 - 11:15 Thyroid Carcinoma in Childhood and Adolescence Motahareh Motazedian/Babak Shafiei

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11:15-11:30 Pathological evaluation of differentiated thyroid cancer in Iranian patients with positive serum thyroglobulin and negative iodine scan Ali Akbar Babaei/Mojtaba Ansari

11:30-11:45 Optimal time of Methimazole discontinuation before I-131 therapy inGravesdisease;ARandomizedControlledTrial. Sayed Rasoul Zakavi

11:45-11:55 Sentinel node mapping in thyroid cancer patients: experience on 30 patients Ramin Sadeghi 11:55-12:05PreventionofRadiationInducedNauseaandVomitingfollowingHighDose131-IodineTherapyinPatientswithDifferentiatedThyroidCancer;ComparisonbetweentheEfficacyofPantoprazol,Ondansetron,andMetoclopramide Marjan Mirzababaee/Babak Shafiei

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12:05 - 12:15 The possibility of total automation in Radio Immunoassay(RIA)? M. Moharamzadeh

12:15 - 12:30 Q&A

12:30 - 13:30 Case discussion 2: nuclear oncology Mohsen Beheshti13:30 - 14:30 Lunch

14:30 - 16:00 Session 6Chairs S.R Zakavi /J.Farahati/D.RoggenbuckCME 4: Thyroid Cancer14:30 - 14:50 Screening for thyroid cancer by Ultrasound and FNAB Jamshid Farahati 14:50 - 15:10 Follow-up of Thyroid cancer Sayed Rasoul Zakavi

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15:10 – 15:30 High sensitive Tg measurement in the follow-up of patients with differentiated thyroid carcinoma Dirk Roggenbuck15:30 – 15:50 PET-Scan in management of thyroid cancer Hojjat Ahmadzadehfar15:50 – 16:00 Q&A

16:00 – 16:30 Break

16:30-17:30 Session 7Panel:TheproblemsofradiationprotectioninnuclearmedicinefieldinIranA.Shabestanimonfared,A.Mozdarani,SR.Zakavi,M.Momennezhad,SMJ.Mortazavi,HRKhosravi,Dr.Aghamiri

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8:15-10:00 Session 8Chairs H.Sayman/K.Aryana /B.FallahiCME5:Infection&InflammatoryDisoreders8:15 – 8:45 The role of Nuclear medicine in lymphedema Ramin Sadeghi8:45 – 9:05 FDGPET–CTimagingininfectionandinflammation Halluk B. sayman9:05 – 9:20 Diagnosticvalueof99mTc-labeled-Ubiquicidin29-41 Scan in differentiation of osteomyelitis from bone tumors Kamran Aryana9:20-9:30 Sentinel node mapping in Marjolin’s ulcer: A feasibility study Ramin Sadeghi9:30-9:40 Molecular imaging of protein-protein interactions in living cells M.Seyedabadi/M.Asadi

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9:40-9:50 Cherenkov Molecular Imaging: review article Ali Mahmoud Pashazadeh

9:50 – 10:00 Q&A

10:00 – 10:30 Break

10:30-12:00 Session 9 Chairs S.R.Zakavi, M.Reza Ay, D.BeikiJointsession(Physics,radiopharmacy&clinicalnuclearmedicine)

10:30 – 10:50 What the clinician expected from physicist and radiopharmacist? Sayed Rasoul Zakavi 10:50 – 11:05 The role of radiopharmacist in molecular imaging wards Davood Beiki11:05 – 11:25 The role of physicist in molecular imaging wards Mohammad Reza Ay

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11:25 – 11:50 ChallengesandPitfallsinLunchingthefirstMedicalCyclotroninIran Pardis Ghafarian

11:50 – 12:00 Q&A

12:00 – 13:30 Ending Ceremony & Awards

13:30 – 14:30 Lunch

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8:00 – 9:00 Openingceremony(InZomorrodHall)

9:00-10:30 Session 1Chairs M. Hamidian - S. Shahhoseini

9:00 – 9:30 PET-CT :Instrument & techniques P. Ghafarian9:30 - 9:50 PET radiopharmaceuticals S. Shahhoseini9:50 – 10:20 Cardiac PET imaging M. Hamidian

10:20 – 10:30 Q&A

10:30-11:00 Break

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11:00-12:30 Session 2Chairs M. Amiri - M. J. Mortazavi

11:00 – 11:20 Octreotid scan M. Amiri11:20-11:50 Radiation hormesis and radioadaptive response SM. J. Mortazavi11:50-12:20 Application of PET in oncologic imaging S. Farzanefar12:20 – 12:30 Q&A

13:30 – 14:30 Lunch

14:30-16:00 Session 3Chairs M. Momennezhad - A.R. Jalilian

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14:30 – 15:00 Management of radioactive contamination in nuclear medicine departments M. Momennezhad15:00 – 15:30 Non technetium SPECT radiopharmaceuticals A.R. Jalilian 15:30 – 15:50 BoneDensitometry M. Amiri15:50 – 16:00 Q&A

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8:30-10:30 Session 4Chairs A. Shabestani Monfared - D. Beiki

8:30 – 8:50 Radiationprotectionregulationinnuclearmedicinedepartments:past,present,future A. Shabestani Monfared8:50 – 9:20 Generatorbasedradiopharmaceuticals(NonTc-99m) D. Beiki9:20 – 9:50 MIBG scan E. Gharepapagh

9:50-10:10 Parathyroid Scan A. Khancherly10:10 – 10:30 Q&A

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10:30 – 11:00 Break

11:00-12:30 Session 5Chairs H. Khosravi - S. Farzanehfar

11:00 – 11:20 Tc99mradiopharmaceuticalsqualitycontroltests H. Sadeghpoor11:20 – 11:40 Nuclear medicine (technologist / patients) and pregnancy H.R. Khosravi11:40 – 12:00 Using Ga 67 in tumor imaging S. Farzanefar

12:00 – 12:20 The NM technologist professional care and communicate relationship with patient M. Hamidian12:20 – 12:30 Q&A

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13:30 – 14:30 Lunch

14:30-15:30 Session 6Chairs M.A. Mosleh – S. M. EntezarmahdiWorkshop including hospital visit (part I) :14:30 – 15:00 Radiation measurement instruments M.A. Mosleh 15:00 – 15:30 Computer in Nuclear Medicine S. M. Entezarmahdi

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8:30-10:00 Session 7Workshop including hospital visit (part II) :8:30-9:15 Computer in Nuclear Medicine S. M. Entezarmahdi 9:15-10:00 Radiation measurement instruments M.A. Mosleh

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8:00 – 9:00 Opening ceremony (In Zommorod Hall)

9:00-10:30 Session 1Chairs Dr. Monfared- Dr. Mortazavi- Dr. Mozdarani- Dr. KhosraviRadiobiology,DosimetryandRadiationProtection9:00-9:20 Radio-protective roles of antioxidant agents A. Shirazi9:20-9:40 Lead-Free Radiation Shields: Should we Move to Nano-sized Structures S.M.J. Mortazavi

9:40-9:50 FetalandMaternalDoseAssessmentforThyroidImagingandTherapyin early pregnancy E. Hoseinian Azghadi

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9:50-10:00 Investigation of implementation of health physics protocols and radiation protection standards in nuclear medicine sections of Shiraz hospitals M. Zehtabian10:00-10:10 Dosecalculationradiopharmaceutical153Sm-EDTMPfortherapyofbone metastases F. Razghandi10:10-10:20 PatientandStaffDoseOptimizationinNuclearMedicineDiagnosisMethods S. Abedi

10:20-10:30 Radioprotective effects of famotidine and vitamin C against radiation induced micronuclei in mice bone marrow in vivo M.Zangeneh

10:30-11:00 Break

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11:00-13:30 Session 2Chairs Dr. Rajabi, Dr. Ay, Dr. KnollPhysics,InstrumentationandSoftware11:00-11:20 Responsibilities of a physicist in a NM/PET department: a personal point of view Peter Knoll11:20-11:40 Molecular Imaging Instrumentation Mohammad Reza Ay11:40-11:50 OpticalPhotonTransportin2DArraysofScintillationDetectors:Develop ment of a New Monte Carlo Model MA. Mosleh Shirazi11:50-12:00 InvestigationofAccuracyofDynamicMyocardialPerfusion 201-Thallium SPECT in comparison of Static Imaging Z. Shahpouri12:00-12:10 TheInfluenceofMisregistrationonQuantitativeAccuracyofAttenuation Corrected SPECT Images H.Babaeifar

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12:10-12:20 Spatial Resolution and System Sensitivity in a Tilted-Head Planar-SPECT: a Monte Carlo Study H. Mahani12:20-12:30 TheEffectofShape,SizeandArrangementofPMT’sontheIntrinsicSpatial Resolution of Anger Camera R. Haghshenas

12:30-12:40 ValidationofGATEMonteCarloCodeforInternalDosimetry (Phantom Study) M.Momennezhad

12:40-12:50 QuantificationofCTandPETImagesMismatchEffectduetoRespiratoryMotioninLungTumorsUptakeValue. H.Soufi

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12:50-13:00 Performance evaluation of HiReSPECT a dedicatedanimal SPECT systemusingmodifiedNEMAstandards V.Moji13:00-13:10 Implementation of Parallel Computing Platform for Monte Carlo SimulationinNuclearMedicineDiscipline Sh. Nasseri13:10-13:20 A new energy mapping algorithm based on spectral CT images: application in PET/CT attenuation correction H. Ghadiri13:20-13:30 Results of the measurement of the Collimator Hole Angulation for different collimators of SPECT with Adaptive Quality Control Phantom H.Zamani Zeinali

13:30 – 14:30 Lunch

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14:30-16:00 Session 3Chairs Dr. Beiki, Dr. Erfani, Dr. ShahhosseiniRadiopharmacy14:30-14:50 Radiopharmaceuticals in Pregnant and Lactating Women Davood Beiki14:50-15:00 RaliolabelingandEvalutionofPAMAMDenderimerCoatedSuperparamag netic Iron Oxide Nanoparticles N.Gholipour15:00-15:10 ImagingTumorInducedApoptosisUsing99mTechnetium–AnnexinVIn Experimental Animals S.Rajabifar 15:10-15:20 SkeletalUptakeandUrinaryExcretionEvaluationof153Sm-EDTMPasa Bone Pain Palliative Radiopharmaceutical Based on Animal Studies M. Meftahi

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15:20-15:30 Feasibility Study of Radium-223 Production in Tehran Research Reactor for Treatment of Bone Metastases R. Bagheri15:30-15:40 PreparationAndEvaluationOf177LuComplexOfZoledronicAcidForus ing In Nuclear Medicine Mirsaeed Nikzad15:40-15:50 BiologicalEvaluationofaNewDerivativeofSubstancePLabeledwithThechnetium-99mforTumorImaging S. Mozaffari15:50-16:00 Evaluationof99mTc-OfloxacinImagingefficacyinEscherichiaColiInduced mice muscle Infection A. Andishmand

16:00-16:30 Break

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16:30-17:30 Session 4Chairs Dr. Jalilian, Dr. Erfani, Dr. SadeghpourRadiopharmacy16:30-16:50 Progress in Peptide Based Radiopharmaceuticals Mostafa Erfani16:50-17:00 PreparationandQualityControlof99mTc-TRODAT-1asaDopamine Transporter Imaging Agents M. Erfani17:00-17:10 Developmentandevaluationofaholmium-166labelledporphyrincomplex as a possible therapeutic agent N. Vahidfar17:10-17:20 NewNeurotensinAnalogLabeledwith99mTcforTargetedTumorsImaging N. Zarrabi Ahrabi17:20-17:30 Quality Control of Radiopharmaceuticals in Shiraz Namazi Hospital H. Sadeghpour

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8:30-10:30 Session 5Chairs Dr. Sadri, Dr. Shahhosseini, Dr. HosseinimehrRadiopharmacy8:30-8:40 Formulation and characterization of PEG-Nano Liposomes labeled with99mTc-HMPAO,forscintigraphicImagingofBloodPoolinanimalmode K.Sadri 8:40-8:50 Productionandqualitycontrolof177Lu-DOTA-AvastinforRadioimmuno diagnostic and Radioimmunotherapeutic Applications K. Yavari8:50-9:00 ¹³¹I-bevacizumab as a target molecule for vascular endothelial growth factor in tumors S.J. Hoseinimehr9:00-9:10 Production and quality control of 166HO poly (L-lactic acid) microspheres for Radiosynovectomy K. Yavari

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9:10-9:20 comparisonof99mTc-chitosannanoparticlewith99mTc-Sullforcolloidand99mTc-phytate:Biodistributionandnuclearimaging S. salehi zahabi9:20-9:30 The Role of Rhenium Radiopharmaceuticals In Nuclear Medicine B.Aziz Kalantari9:30-9:40 GuidanceonFacilityDesign,ProductionandQualitycontrolof[18F]FluoroDeoxyGlucose(FDG) M. Akhlaghi9:40-9:50 RadionuclidePurityAssessmentof90YGlassMicrosphereUsingGamma- ray Spectrometry H. Poorbaygi9:50-10:00 EvalutionofaNewBombesinAnalogueLabeledwith99mTcaspotential targeted tumor Sintigraphic agent N. Sadeghzadeh

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10:00-10:10 Determinationofhumanabsorbeddoseof153Sm-TPTTCbasedon distribution data in rats A. Hakimi10:10-10:20 Tc-99mRaliolabelingofDoxorubicinLoadedDenderimerCoatedSuper paramagnetic Iron Oxide Nanoparticles N.Gholipour10:20-10:30 Determinationofbindingparametersof3H-Flumazeniltoratcorticalmembranereceptorsusingfiltrationandcentrifugationmethodstoseparateboundfromunbound. F. Ahmadi

10:30 – 11:00 Break

11:00-13:30 Session 6Chairs Dr.Monfared- Dr. Shirazi- Mrs. Mehdizadeh- Dr. Aghamiri

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Radiobiology,DosimetryandRadiationProtection11:00-11:20 RadiobiologicalConcernsforLowDoseOccupationalExposure Hossein Mozdarani

11:20-11:35 The Role of Automation in Accurate Calibration of RadiopharmaceuticalsforDiagnosticNuclearMedicine S. Mehdizadeh

11:35-11:50 HowRiskEstimationCanBeReplacedbyBenefitEstimation? (A More Positive Approach to Radiation Protection in Nuclear Medicine) Ali Shabestani Monfared11:50-12:00 PatientSpecificDosimetrybyDosePointKernelofRadionuclidesUsedin Nuclear Medicine with GATE A. Parach

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12:00-12:10 OccupationalRadiationExposure,DNADamageandGeneticPolymorphismsinDNARepairGenes F. Zakeri12:10-12:20 EffectiveDoseCalculationaroundFukushimaDai-ichiNuclearPowerPlant from Contaminated Soil M. Kiani-Nasab 12:20-12:30 Radioactive waste handling and disposal at nuclear medicine departments in Shiraz,Iran A.Banani12:30-12:40 Equivalent dose to staffs in different procedures of Nuclear Medicine M.S. Shobeiri12:40-12:50 Continuous monitoring and control of ionizing air system in nuclearmedicine,radiotherapyandradiologydepartments I. shiri

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12:50-13:00 CalculationofContainerThicknessandDepthContaminationsofGammaEmittersinShieldingsatNuclearMedicineCenterswithTwoDetecotrs E. Saniei13:00-13:10 InternalDosimetryinNuclearMedicineUsingGateandXCATPhantom: a Simulation Study M. Fallahpoor13:10-13:20 Statistical Analyses of surface contamination of recursive Thallium and Gallium lead shielding from country’s nuclear medicine centers A. Bahrami13:20-13:30 Evaluation of the sensitivity of a dose calibrator to pure beta radiation H. Poorbaygi

13:30 – 14:30 Lunch

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14:30-16:00 Session 7Chairs Dr. Rajabi, Dr. Faghihi, Dr. KnollPhysics,InstrumentationandSoftware14:30-14:50 Dosimetryintherapeuticapplicationofradioisotopes Hosein Rajabi14:50-15:10 Quality control of SPECT gamma cameras Peter Knoll15:10-15:20 Monte Carlo Study of Radiation Scattering and Its Impact on Nuclear Medicine Image Quality in Planar Imaging with Multislice FanBeam Collimator HR. Baghani15:20-15:30 Evaluating of Neurogam software accuracy in semi quantitative analysis of brain SPECT images M. Rezaeian15:30-15:40 Feasibility Study of Myocardial Perfusion Imaging with Fan-Beam in Comparison of Parallel-Hole Collimator A. Mehravar

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15:40-15:50 Designinganddevisingsuperficialcontaminationrecognitionmonitorin nuclear medicine centres M. Poshtkouhyan Bavi15:50-16:00 DoDifferentFiltrationMethodsAffectonCalculatedVolumeandEjection Fraction Value by the QBS? S.Mohseni

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With cooperation of research vice-Chancellor of Shiraz University of Medical Sciences