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44464842 ECG Project Report

Jul 07, 2018

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      Table Of Contents

    1. Acknowledgements.

    2. Certificate

    3. Introduction to the project

    . !asics of "C#

    $. Circuit diagram

    %. &orking of "C#

    '. (atlab !asics

     

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    ACKNOWLEDGEMENT

    It is with pleasure that we find oursel)es penn* down

    these line to e+press our sincere thanks to )arious people to

    help me along the wa* in completing this work.

    I am helpful to (r. !.,.!rar- (iss #urwinder aur / (r.

    A.C. (ongra who ga)e me chance to go outside the college for 

    the training. Also thankful to (r. Abina)- who taught me

    during the % week training.

    I also thankful to m* parents / dearest who help me in

    doing this report.

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    Introduction

    The electrocardiogram 0"C# or "# is a diagnostic tool that measures and

    records the electrical acti)it* of the heart in e+uisite detail. Interpretation of these

    details allows diagnosis of a wide range of heart conditions. These conditions can

    )ar* from minor to life threatening.

    The term electrocardiogram was introduced b* &illem "intho)en in 143 at a

    meeting of the 5utch (edical ,ociet*. In 142- "intho)en recei)ed the 6obel

    7ri8e for his life9s work in de)eloping the "C#.

    The "C# has e)ol)ed o)er the *ears.

    • The standard 12:lead "C# that is used throughout the world was introduced

    in 142.

    • It is called a 12:lead "C# because it e+amines the electrical acti)it* of the

    heart from 12 points of )iew.

    • This is necessar* because no single point 0or e)en 2 or 3 points of )iew

     pro)ides a complete picture of what is going on.

    • To full* understand how an "C# re)eals useful information about the

    condition of *our heart reuires a basic understanding of the anatom* 0that

    is- the structure and ph*siolog* 0that is- the function of the heart.

    Basic Anatomy of the Heart

    The heart is a :chambered muscle whose function is to pump blood throughout

    the bod*.

    • The heart is reall* 2 ;half hearts-; the right heart and the left heart- which

     beat simultaneousl*.

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    • "ach of these 2 sides has 2 chambers< a smaller upper chamber called the

    atrium 0together- the 2 are called atria- and a larger lower chamber called

    the )entricle.

    Thus- the chambers of the heart are called the right atrium- right )entricle-left atrium- and left )entricle.

    This seuence also represents the direction of blood flow through the heart.

    • The right atrium recei)es blood that has completed a tour around the bod*

    and is depleted of o+*gen and other nutrients. This blood returns )ia 2 large

    )eins< the superior )ena ca)a returning blood from the head- neck - arms-

    and upper portions of the chest- and the inferior )ena ca)a returning blood

    from the remainder of the bod*.

    • The right atrium pumps this blood into the right )entricle- which- a fraction

    of a second later- pumps the blood into the blood )essels of the lungs.

    • The lungs ser)e 2 functions< to o+*genate the blood b* e+posing it to the air 

    *ou breathe in 0which is 2=> o+*gen- and to eliminate the carbon dio+ide

    that has accumulated in the blood as a result of the bod*9s man* metabolic

    functions.

    • ?a)ing passed through the lungs- the blood enters the left atrium- which

     pumps it into the left )entricle.

    • The left )entricle then pumps the blood back into the circulator* s*stem of 

     blood )essels 0arteries and )eins. The blood lea)es the left )entricle )ia the

    aorta- the largest arter* in the bod*. !ecause the left )entricle has to e+ert

    enough pressure to keep the blood mo)ing throughout all the blood )essels

    of the bod*- it is a powerful pump. It is the pressure generated b* the left

    )entricle that gets measured when *ou ha)e *our blood pressure checked.

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    The heart- like all tissues in the bod*- reuires o+*gen to function. Indeed- it is the

    onl* muscle in the bod* that ne)er rests. Thus- the heart has reser)ed for itself its

    own blood suppl*.

    • This blood flows to the heart muscle through a group of arteries that begins

    less than one:half inch from where the aorta begins. These are known as the

    coronar* arteries. These arteries deli)er o+*gen to both the heart muscle

    and the ner)es of the heart.

    • &hen something happens so that the flow of blood through a coronar*

    arter* gets interrupted- then the part of the heart muscle supplied b* that

    arter* begins to die. This is called coronar* heart disease- or coronar* arter*

    disease. If this condition is not stopped- the heart itself starts to lose its

    strength to pump blood- a condition known as heart failure.

    • &hen the interruption of coronar* blood flow lasts onl* a few minutes- the

    s*mptoms are called angina- and there is no permanent damage to the heart.

    &hen the interruption lasts longer- that part of the heart muscle dies. This is

    referred to as a heart attack  0m*ocardial infarction.

     6er)es of the heart< The heart9s function is so important to the bod* that it has its

    own electrical s*stem to keep it running independentl* of the rest of the bod*9s

    ner)ous s*stem.

    • ")en in cases of se)ere brain damage- the heart often beats normall*.

    • An e+tensi)e network of ner)es runs throughout all chambers of the heart.

    "lectrical impulses course through these ner)es to trigger  the chambers to

    contract with perfectl* s*nchroni8ed timing much like the distributor and

    spark plugs of a car make sure that an engine9s pistons fire in the right

    seuence.

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    • The "C# records this electrical acti)it* and depicts it as a series of graph:

    like tracings- or wa)es. The shapes and freuencies of these tracings re)eal

    abnormalities in the heart9s anatom* or function.

    Basics of ECG

    ECG Electrodes

    ,kin 7reparation<

    Clean with an alcohol wipe if necessar*. If the patients are )er* hair* @ sha)e theelectrode areas.

    "C# standard leads

    There are three of these leads- I- II and III.

    ead I< is between the right arm and left arm electrodes- the left arm being positi)e.

    ead II< is between the right arm and left leg electrodes- the left leg being positi)e.ead III< is between the left arm and left leg electrodes- the left leg

    again being positi)e.

    Chest "lectrode 7lacement

    B1< ourth intercostal space to the right of the sternum.

    B2< ourth intercostal space to the eft of the sternum.

    B3< 5irectl* between leads B2 and B.

    B< ifth intercostal space at midcla)icular line.

    B$< e)el with B at left anterior a+illar* line.

    B%< e)el with B$ at left mida+illar* line. 05irectl* under the

    midpoint of the armpit

    http://www.ambulancetechnicianstudy.co.uk/images/electrodes_position.gif

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    Chest eads

    B1 / B2

    B3 / B

    B$ / B%

    Biew

    Dight Bentricle

    ,eptumEateral eft Bentricle

    AnteriorEateral eft Bentricle

    The "C# records the electrical acti)it* that results when the heart muscle cells in the

    atria and )entricles contract.

    • Atrial contractions show up as the 7 wa)e.

    • Bentricular contractions show as a series known as the FD, comple+.

    • The third and last common wa)e in an "C# is the T wa)e. This is the electrical

    acti)it* produced when the )entricles are recharging for the ne+t contraction

    0repolari8ing.

    • Interestingl*- the letters 7- F- D- ,- and T are not abbre)iations for an* actual

    words but were chosen man* *ears ago for their position in the middle of the

    alphabet.

    • The electrical acti)it* results in 7- FD,- and T wa)es that are of different si8es

    and shapes. &hen )iewed from different leads- these wa)es can show a wide

    range of abnormalities of both the electrical conduction s*stem and the muscle

    tissue of the hearts pumping chambers.

    ECG Interpretation

    The graph paper that the "C# records on is standardised to run at 2$mmEsecond-

    and is marked at 1 second inter)als on the top and bottom. The hori8ontal a+is correlates

    the length of each electrical e)ent with its duration in time. "ach small block 0defined b*

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    lighter lines on the hori8ontal a+is represents =.= seconds. i)e small blocks 0shown b*

    hea)* lines is a large block- and represents =.2= seconds.

    5uration of a wa)eform- segment- or inter)al is determined b* counting the blocks from

    the beginning to the end of the wa)e- segment- or inter)al.

    7:&a)e< represents atrial depolari8ation : the time necessar* for an electrical impulse

    from the sinoatrial 0,A node to spread throughout the atrial musculature.

    • ocation< 7recedes FD, comple+

    Amplitude< ,hould not e+ceed 2 to 2.$ mm in height 5uration< =.=% to =.11

    seconds

    7:D Inter)al< represents the time it takes an impulse to tra)el from the atria through the

    AB node- bundle of ?is- and bundle branches to the 7urkinje fibres.

    • ocation< "+tends from the beginning of the 7 wa)e to the beginning of the FD,

    comple+

    5uration< =.12 to =.2= seconds.

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    FD, Comple+< represents )entricular depolarisation. The FD, comple+ consists of 3

    wa)es< the F wa)e- the D wa)e- and the , wa)e.

    • The F wa)e is alwa*s located at the beginning of the FD, comple+.

    It ma* or ma* not alwa*s be present.

    The D wa)e is alwa*s the first positi)e deflection.

    The , wa)e- the negati)e deflection- follows the D wa)e

    • ocation< ollows the 7:D inter)al

    Amplitude< 6ormal )alues )ar* with age and se+

    5uration< 6o longer than =.1= seconds

    F:T Inter)al< represents the time necessar* for )entricular depolari8ation and

    repolari8ation.

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    • ocation< "+tends from the beginning of the FD, comple+ to the end of the T

    wa)e

    0includes the FD, comple+- ,:T segment- and the T wa)e

    5uration< Baries according to age- se+- and heart rate

    T &a)e< represents the repolari8ation of the )entricles. On rare occasions- a G wa)e can

     be seen following the T wa)e. The G wa)e reflects the repolari8ation of the ?is:7urkinje

    fibres.

    • ocation< ollows the , wa)e and the ,:T segment

    Amplitude< $mm or less in standard leads I- II- and IIIH 1=mm or less in precordial

    leads B1:B%.

    5uration< 6ot usuall* measured

    ,:T ,egment< represents the end of the )entricular depolari8ation and the beginning of

    )entricular repolari8ation.

    ocation< "+tends from the end of the , wa)e to the beginning of the T wa)e

    5uration< 6ot usuall* measured

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    The ECG and Myocardial Infarction

    5uring an (I- the "C# goes through a series of abnormalities. The initial abnormalit* is

    called a hyperacute T wave. This is a T wa)e that is taller and more pointed than the

    normal T wa)e.

    ?*peracute T &a)e

    The abnormalit* lasts for a )er* short time- and then ele)ation of the ,T segment occurs.

    This is the hallmark abnormalit* of an acute (I. It occurs when the heart muscle is being

    injured b* a lack of blood flow and o+*gen and is also called a current of injur*.

    An "C# can not onl* tell *ou if an (I is present but can also show the appro+imate

    location of the heart attack- and often which arter* is in)ol)ed. &hen the "C#

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    abnormalities mentioned abo)e occur- then the (I can be locali8ed to a certain region of 

    the heart. or e+ample- see the table below<

    ECG leads Location of MI Coronary Artery

    II- III- aB Inferior (I Dight Coronar* Arter*

    B1:B Anterior or Anteroseptal (I eft Anterior 5escending Arter*

    B$:B%- I-aB ateral (I eft Circumfle+ Arter*

    ,T depression in B1- B2 7osterior (I eft Circumfle+ Arter* or Dight Coronar* Arter*

    Circuit 5iagram

    Design Considerations

    TI9s new A5,124  pro)ides eight channels of 7#A plus separate 2:bit delta:sigma

    A5Cs- a &ilson center terminal- the augmented #oldberger terminals and their 

    amplifiers- pro)ide for a full- standard 12:lead "C# integrated analog front end. The

    A5,124  reduces component count and power consumption b* up to 4$ percent as

    compared to discrete implementations- with a power efficienc* of 1 m&Echannel- while

    allowing customers to achie)e the highest le)els of diagnostic accurac*

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    ECG System unctionality and Evolution

    !asic functions of an "C# machine include "C# wa)eform displa*- either through C5

    screen or printed paper media- and heart rh*thm indication as well as simple user 

    interface through buttons. (ore features- such as patient record storage through

    con)enient media- wirelessEwired transfer and 25E35 displa* on large C5 screen with

    touch screen capabilities- are reuired in more and more "C# products. (ultiple le)els

    of diagnostic capabilities are also assisting doctors and people without specific "C#

    trainings to understand "C# patterns and their indication of a certain heart condition.

    After the "C# signal is captured and digiti8ed- it will be sent for displa* and anal*sis-

    which in)ol)es further signal processing.

    Si!nal Ac"uisition challen!es#

    • (easurement of the "C# signal gets challenging due to the presence of the large

    5C offset and )arious interference signals. This potential can be up to 3==mB for 

    a t*pical electrode. The interference signals include the $=:E%=:?8 interference

    from the power supplies- motion artifacts due to patient mo)ement- radiofreuenc* interference from electro:surger* euipments- defibrillation pulses-

     pace maker pulses- other monitoring euipment- etc.

    • 5epending on the end euipment- different accuracies will be needed in an "C#<

    o ,tandard monitoring needs freuencies between =.=$:3= ?8

    o 5iagnostic monitoring needs freuencies from =.=$:1=== ?8

    • ,ome of the $=?8E%=?8 common mode interference can be cancelled with a high:

    input:impedance instrumentation amplifier 0I6A- which remo)es the AC line

    noise common to both inputs. To further reject line power noise- the signal is

    in)erted and dri)en back into the patient through the right leg b* an amplifier.

    Onl* a few micro amps or less are reuired to achie)e significant C(D 

    impro)ement and sta* within the G$ limit. In addition- $=E%=?8 digital notch

    filters are used to reduce this interference further.

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    Analo! front end options#

    • Optimi8ing the power consumption and the 7C! area of the analog front end is

    critical for portable "C#9s. 5ue to technological ad)ancements- there are now

    se)eral front end options<

    o Gsing a low resolution A5C 0needs all filters

    o Gsing a high resolution A5C 0needs fewer filters

    o Gsing a sigma:delta A5C 0needs no filters- no amplifier aside from I6A-

    no 5C offset

    o Gsing a seuential Bs simultaneous sampling approach.

    • &hen a low resolution 01% bit A5C is used- the signal needs to be gained up

    significantl* 0t*picall* 1==+ : 2==+ to achie)e the necessar* resolution. &hen a

    high resolution 02bit sigma delta A5C is used- the signal needs a modest gain of 

    : $+. ?ence the second gain stage and the circuitr* needed to eliminate the 5C

    offset can be remo)ed. This leads to an o)erall reduction in area and cost. Also the

    delta sigma approach preser)es the entire freuenc* content of the signal and

    gi)es abundant fle+ibilit* for digital post processing.

    • &ith a seuential approach the indi)idual channels creating the leads of an "C#

    are multiple+ed to one A5C. This wa* there is a definite skew between adjacent

    channels. &ith the simultaneous sampling approach- a dedicated A5C is used for 

    each channel and hence there is no skew introduced between channels.

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    $or%in! of ECG

    The "C# works mostl* b* detecting and amplif*ing the tin* electrical changes on the

    skin that are caused when the heart muscle ;depolarises; during each heart beat. At rest-

    each heart muscle cell has a charge across its outer wall- or cell membrane. Deducing this

    charge towards 8ero is called de:polarisation- which acti)ates the mechanisms in the cell

    that cause it to contract. 5uring each heartbeat a health* heart will ha)e an orderl*

     progression of a wa)e of depolarisation that is triggered b* the cells in the sinoatrial

    node- spreads out through the atrium- passes through ;intrinsic conduction pathwa*s; and

    then spreads all o)er the )entricles. This is detected as tin* rises and falls in the )oltage

     between two electrodes placed either side of the heart which is displa*ed as a wa)* line

    either on a screen or on paper. This displa* indicates the o)erall rh*thm of the heart and

    weaknesses in different parts of the heart muscle.

    Gsuall* more than 2 electrodes are used and the* can be combined into a number of pairs

    0or e+ample< eft arm 0A- right arm 0DA and left leg 0 electrodes form the pairs<

    ADA- A- DA. The output from each pair is known as a lead. "ach lead is

    said to look at the heart from a different angle. 5ifferent t*pes of "C#s can be referred to b* the number of  leads that are recorded- for e+ample 3:lead- $:lead or 12:lead "C#s

    0sometimes simpl* ;a 12:lead;. A 12:lead "C# is one in which 12 different electrical

    signals are recorded at appro+imatel* the same time and will often be used as a one:off 

    recording of an "C#- t*picall* printed out as a paper cop*. 3: and $:lead "C#s tend to be

    monitored continuousl* and )iewed onl* on the screen of an appropriate monitoring

    de)ice- for e+ample during an operation or whilst being transported in an ambulance.

    There ma*- or ma* not be an* permanent record of a 3: or $:lead "C# depending on the

    euipment used.

    http://en.wikipedia.org/wiki/Cell_membranehttp://en.wikipedia.org/wiki/Sinoatrial_nodehttp://en.wikipedia.org/wiki/Sinoatrial_nodehttp://en.wikipedia.org/wiki/Atrium_(heart)http://en.wikipedia.org/wiki/Ventricle_(heart)http://en.wikipedia.org/wiki/Voltagehttp://en.wikipedia.org/wiki/Electrocardiography#Leadshttp://en.wikipedia.org/wiki/Cell_membranehttp://en.wikipedia.org/wiki/Sinoatrial_nodehttp://en.wikipedia.org/wiki/Sinoatrial_nodehttp://en.wikipedia.org/wiki/Atrium_(heart)http://en.wikipedia.org/wiki/Ventricle_(heart)http://en.wikipedia.org/wiki/Voltagehttp://en.wikipedia.org/wiki/Electrocardiography#Leads

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    It is the best wa* to measure and diagnose abnormal rh*thms of the heart- J2K particularl*

    abnormal rh*thms caused b* damage to the conducti)e tissue that carries electrical

    signals- or abnormal rh*thms caused b* electrol*te imbalances.J3K  In a m*ocardial

    infarction 0(I- the "C# can identif* if the heart muscle has been damaged in specific

    areas- though not all areas of the heart are co)ered.JK The "C# cannot reliabl* measure

    the pumping abilit* of the heart- for which ultrasound:based 0echocardiograph* or 

    nuclear medicine tests are used. It is possible to be in cardiac arrest with a normal "C#

    signal 0a condition known as pulseless electrical acti)it*.

    http://en.wikipedia.org/wiki/Electrocardiography#cite_note-1http://en.wikipedia.org/wiki/Electrocardiography#cite_note-ECG_Noncardiac-2http://en.wikipedia.org/wiki/Electrocardiography#cite_note-ECG_Noncardiac-2http://en.wikipedia.org/wiki/Myocardial_infarctionhttp://en.wikipedia.org/wiki/Myocardial_infarctionhttp://en.wikipedia.org/wiki/Electrocardiography#cite_note-ECC_2005_ACS-3http://en.wikipedia.org/wiki/Echocardiographyhttp://en.wikipedia.org/wiki/Nuclear_medicinehttp://en.wikipedia.org/wiki/Pulseless_electrical_activityhttp://en.wikipedia.org/wiki/Electrocardiography#cite_note-1http://en.wikipedia.org/wiki/Electrocardiography#cite_note-ECG_Noncardiac-2http://en.wikipedia.org/wiki/Myocardial_infarctionhttp://en.wikipedia.org/wiki/Myocardial_infarctionhttp://en.wikipedia.org/wiki/Electrocardiography#cite_note-ECC_2005_ACS-3http://en.wikipedia.org/wiki/Echocardiographyhttp://en.wikipedia.org/wiki/Nuclear_medicinehttp://en.wikipedia.org/wiki/Pulseless_electrical_activity

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    A&'A(TAGES

    ow cost and high co)erage

    ,ecure transmission solution"fficient e+change of )ital signs

    "as* to interfacing medical instrument to computer 

    Applications

    (onitoring and control platforms

    "lectronic medical record s*stems!io:medical applications

    5atabase management s*stems