3Dnet Suite Brochure

CALCIUM SCORING

Calcium Scoring is used extensively around the world as a trusted method of screening and assessing the risk of coronary artery disease, which affects millions of people around the world.

3DnetTM Calcium Scoring provides tools that can deliver rapid and accurate assessment of calcium in the entire coronary artery tree and provide a detailed quantitative assessment for physicians.

• Agaston and volume scoring for full vessels or vessel segments allows for complete or targeted assessments.

• One click segmentation of coronary arteries for both contrast enhanced and non-contrast studies as well as customisable colour coding of calcium thresholds.

• Detailed, quantitative calcium scoring reports with volume, Max HU, Av. HU and plaque data are generated for each artery along with graphical representation of the risk factor associated with the score for the patient according to their gender and age.

Faster.3Dnet’s unique core design optimises memory and computer resource utilisation allowing for quick rendering of very large image volumes.

Easier. 3Dnet™ Calcium Scoring is designed to adapt to doctors’ needs with a dedicated workflow, screen layoutand additional measurement and annotation features all managed through an easy-to-use interface.

Better. 3Dnet™ Calcium Scoring can be run on off the shelf hardware and can be integrated seamlessly into any RIS/PACS environment.

CALCIUM SCORING FEATURESFull Quantitative ScoringVolume, Agatston, Max HU, AV. HU and plaque data are generated for each artery with the ability to quickly switch between artery selections.

One Click Vessel SegmentationOne click segmentation of vessels with the option to score slice by slice for sections of vessels.

Fully Customisable Calcium ThresholdingPredefined thresholding presets and the ability to create and save customisedthreshold presets.

Study Comparison ModeCompare prior studies with current studies to establish changes over time.

Detailed ReportingAutomatically generated quantitative reports with assessment of risk for patients based on clinically validated guidelines.

Measurement and Annotation ToolsProvides a broad range of tools including length, diameters, angles, text comments for additional comments and image captures.

Cine ModeRapid navigation of coronary arteries in multiple image planes.

Fully Integrated With Your RIS/PACS3Dnet™ Calcium Scoring can be easily integrated into the RIS/PACS environment.

Biotronics3D Headquarters1 Park Pl, Canary Wharf Docklands, London, E14 4BE, UKT+44 (0) 207 093 [email protected]

Biotronics3D Innovation Centre (BIC)Orwell House, CowleyRoad,Cambridge, CB4 0PP, UKT+44 (0) 1223 [email protected]

© Biotronics3D Ltd. 3DCS100217/A

www.biotronics3d.com

0344Recommended System SpecificationsQuad core 64 Bit Processor, Windows 7/Vista/XP, 8GB RAM, 200MB hard disk space,nVidia Quadra graphics card (dual head if multi-monitor support is required)

Faster and more accurate diagnoses through extensive,easy-to-use & cutting-edge tools for CT Colonoscopy.

• Designed for individuals ― supporting for all the common reading types using a combination of undistorted dissected colon, endoluminal flythrough and 2D layouts.

• Leading edge productivity tools to allow rapid analysis, measurement and reporting of suspected polyps and lesions with an option for CAD.

• Never leave your PACS workstation with seamless integration into PACS.

Faster. 3Dnet™ Colonoscopy unique core design optimises memory and computer resource utilisation allowingfor quick rendering of image volumes and rapid reading and reporting.

Easier. 3Dnet™ Colonoscopy is designed to adapt to users needs according to user profiles. As a result, theeasy-to-use interface can be as feature-rich or as simple as desired.

Better. Improve relations with patients with faster turn-around times, completing more studies inless time and more accurately.

COLONOSCOPY

COLONOSCOPY


FEATURESMulti Reading Protocols with Synchronised 2D and 3D Images• 2D axial, sagittal and coronal views with fast scrolling and colon tracking updated in all views.

• 3D endoluminal flythrough with automated cine mode, free rotation and one click zoom on selected areas of interest.

• 3D dissected colon view allowing rapid assessment of the entire colon surface area.

Comparison ModeDisplay prone and supine datasets simultaneously on the same screen (or on different screens). The datasets can be the same volume displayed at different settings or the volumes can be linked for comparison mode.

Automatic Colon Segmentation and Centerline ExtractionAbility to track through blocked or poorly insufflated sections of the colon.

Auto Measure Distance from Rectum to CaecumAllows for endoscopy to navigate easily to area of interest for polypectomies.

Visited Regions AnalysisQuickly identifies the visited regions to accelerate the speed of reporting and ensure no areas are missed from reading.

Single-Click BookmarkingSingle click tool which allows for rapid bookmarking and return to identified regions ofinterest and suspected polyps and lesions.

Translucent AnalysisApply a translucency filter to regions of interest in 3D views and assess lesion composition in order to reduce false positives created by fecal matter.

Extracolonic Findings ReportingCapture and report on extracolonic findings or fast switch into other 3Dnetapplications to perform more rigorous analysis

Measurement & AnnotationAdd lengths, diameters, angles, text comments and insert arrows with annotationsupdated in all views.

Advanced Polyp Analysis Option (CAD/CAM)*Advanced polyp analysis for automatic detection of polyps (CAD) and automaticmeasurement of polyps (CAM) (this is an additional option, not part of the standard product).

Record Video ClipsInclude in reports or export for use in presentations or burn onto DVD for patients.

PACS/RIS3Dnet™ Colonoscopy can be easily integrated into the RIS/PACS environment.

*Not available in the USA

0344Recommended Recommended System Specifications:Quad core 64 Bit Processor, Windows 7/Vista/XP,8GB RAM, 200MB hard disk space, nVidia Quadra graphics card

CT LUNG ANALYSIS

Quantitative CT lung analysis just got faster, easier, better.Faster and more accurate diagnoses through extensive, easy-to-use and cutting-edge tools for analysis of the lungs.

Identifying, assessing and performing quantitative analysis of lung nodules is both challenging and time consuming. Nodules often have irregular shapes or are located very close to the edge of the lungs or vessels. 3Dnet Lung is designed to simplify, accelerate, assess and report lung nodules with far less of a burden.

• Single click quantitative assessment of lung nodules with volumetric, linear and density measurements automatically generates and highlights nodules in zoomed 3D volume rendered review window.

• Leading edge productivity tools allows rapid bookmarking, analysis and reporting of suspected nodules and lesions, with an option for CAD and the ability to compare prior studies to assess growth of nodules or lesions.

• Never leave your PACS workstation with seamless integration into PACS.

Faster. 3Dnet™ CT Lung Analysis unique core design optimises memory and computer resource utilisation, allowing for quick rendering of image volumes and rapid reading and reporting.

Easier. 3Dnet™ CT Lung Analysis is designed to adapt to users needs according to user profiles. As a result, the easy-to-use interface can be as feature-rich or as simple as desired.

Better. Improve relations with patients resulting faster turn-around times, completing more studies in less timeand more accurately.

FEATURESComprehensive Image Rendering ModesA complete range of MPR, MIP and 3D volume rendering modes providing optimal viewing and flexibility for different reading methods

Comparison modeDisplay two studies on the same screen or seperate screens allowing for side-by- side multimodality comparison of current and prior studies. Studies can be the same volume displayed at different settings or the volumes can be linked.

Nodule SegmentationOne click nodule segmentation providing instantaneous volumetric, area, and diameter measurements. All of which are automatically exported when findings are confirmed.

Nodule ManagementSimple and quick bookmarking of nodules allowing for rapid navigation back to suspicious areas, thus improving reading workflow and allowing “on-the-fly” labelling and reporting or bookmark reviewing after reading the study completely.

ROI/Visual 3D ShuttersAdjustable clip-planes to remove objects quickly and easily from the view and concen-trate on targeted regions of interest

Advanced Nodule Analysis option (CAD)▼Increased sensitivity and specificity using advanced nodule detection of polyps using CAD (computer aided detection).This is an additional option, not part of the standard product.

Measurements and AnnotationsQuickly add lengths, diameters, angles, text, comments and insert arrows.

View Layout/Multiple ViewsFlexibility for numerous types of view layouts depending on the type of study or personal user preference.

Study reporterOutput selected views to create pre-defined, editable reports ,reducing the time to complete an exam and increasing departmental throughput.

Fully integrated with your RIS/PACS3Dnet™ Lung can be easily integrated into the RIS/PACS environment.

― Not available in the USA


Biotronics3D Innovation Centre (BIC)Orwell House, CowleyRoad,Cambridge, CB4 0PP, UKT+44 (0) 1223 [email protected]© Biotronics3D Ltd. 3DLU100217/A



DIAGNOSTICS3D

Diagnostic3D for the Enterprise: see things from a newperspective.The continuing drive to shorten the cycle between scans and results, as well asimproving point-of-care for patients regarding their condition and treatment options,3Dnet™ Suite Diagnostic 3D transforms imaging capabilities for healthcare organisations.

What enables 3Dnet™ Suite Diagnostic3D to be successfully deployed throughout the enterprise is its ability to:

• Perform optimally over a standard network without requiring specialized hardware or bandwidth capabilities

• Provide a user interface that is intuitive enough that medical staff not specialized in radiology may easily use the software

• Seamless integration into PACS or RIS further improving productivity without the need for numerous expensive or specialised hardware installations.

Diagnostic3D’s ease-of-use makes it perfect for the radiologists, clinicians, technologists and any other specialty profession-als outside radiology.

3Dnet™ is Biotronics3D advanced technical framework for delivering advanced visualisation wherever and whenever it is required. Its highly innovative and unique core design allows for cutting-edge 3D functionality on a local PACS workstation or to more remote locations. Where as, hardware constraints would otherwise prohibit the use of advanced visualisation through a server based thin client.

FEATURESDIAGNOSTICS3D FEATURESEnterprise Advanced Visualisation With both Thin client and Rich ClientComplete 3D functionality delivered anywhere in the imaging enterprise throughsecure thin client or rich client providing for remote use on low specification hardware.

Comprehensive Image Rendering ModesMPR, MIP, MinIP, AvIP, SSD, CPR, DVR(color), DVR(gray) with simple W/L thresholding.

Advanced Multiplaner Reconstruction (MPR)Simple to create CPR (Curved Multiplanar Reconstructions), obliques and doubleobliques to providing ideal visualisation for a variety of studies such as blood vessels orcomplex fractures.

Fast Slabbing for MDCT ReadingReal-time, rapid reformatting into slabs for reading of CT scans with all data automati-cally saved back into the study file.

Comparison ModeDisplay two datasets on the same screen or on different screens. allowing for sideby-side multimodality comparison of current and prior studies. Datasets can be thesame volume displayed at different settings or can be linked.

Segmentation and Pre-SetsNumerous one-click presets for rapid selection of key structures such as lungs, boneor vessels and the ability to create, save and import/export customized pre-sets.

VOI Volume of Interest/ Visual 3D ShuttersProvides clip-planes to remove objects quickly and easily from view.

Extensive Multi-Modality SupportVirtually all DICOM studies from CT, MRI, DR, PET, SPECT and US

Measurement & AnnotationSave lengths, diameters, angles, add text comments and insert arrows.

Volumetric ToolsSemi-automated tool to perform volumetric and area measurements on arbitrary 3D structures.

Volume De-Composition into Anatomical ComponentsSemi-automatic segmentation, 3D component calculation, measurement,quantitative report and visualisation.

View Layout/Multiple ViewsFlexibility for numerous types of view layouts depending on the type of study orpersonal user preference.

Fully integrated with Your RIS/PACS3Dnet™ Diagnostic3D can be easily integrated into the RIS/PACS environment.



© Biotronics3D Ltd. 3D3D100217/A



MRI PERFUSIONFaster, more detailed and accurate diagnoses through extensive, easy-to-use and cutting-edge tools for DCE MRI Perfusion.

• Benefit from market leading model implementations, use of custom pharmacokinetics or input function models.

• Optimised workflow for the most promising imaging modality and method of assessment in quantitative functional analysis.

• 3Dnet™ DCE-MRI Perfusion can be integrated seamlessly into the RIS/PACS environment.

Faster. 3Dnet™ DCE-MRI Perfusions’ unique core design optimises memory and computer resource utilisation allowingfor quick rendering of image volumes.

Easier. 3Dnet™ DCE-MRI Perfusion is designed to adapt to doctors’ needs according to user profiles with an easy-to-use interface that can be as feature-rich or as simple as users desire.

Better. 3Dnet™ DCE-MRI Perfusion permits in-depth quantitative functional analysis, enhancing structures to enable an accurate assessment of the response to therapy.

FEATURESWorkflow CentredSimple and intuitive step-by step process from signal intensity to contrast agentconcentration conversion, Pharmakokinetic modelling, and dynamic analysis.

DCE-MRI AnalysisReliable DCE-MRI analysis clinically validated by the Institute of Cancer Research and the Royal Marsden Hospital in London, UK.

Analysis OutputContrast Agent Concentration, Transfer constant (kTrans), EES volume fraction (ve),Rate constant (kep), Plasma volume fraction (vp), cell fraction, goodness of fit,onset time, and area under the curve for every voxel analysed.

DCE-MRI MapsThe above parameters can be seen overlaid on the data and average concentration/time curves and region histograms. Each parameter can be visualised and exported.

Custom ModelsIn addition to our default state-of-the-art Pharmacokinetics models, you can specifyyour own model or Input Function to be seamlessly implemented in the application.

Advanced MPRInteractive Multi-Planar & double oblique reconstructions, MinIP, AvIP. MIP. Numerous view Layouts supporting 2D, 3D or a combination of both.

Measurement & AnnotationSave lengths, diameters, angles, add text comments and insert arrows.

Volumetric ToolsSemi-automated tool to perform volumetric and area measurements on arbitrary 3D structures.

Image ProcessingTime and spatial navigation, image subtraction, and special filtering options.

Comparison mode: Support for Two DatasetsDisplay two datasets on the same screen or different screens. The datasets canbe the same volume displayed at different settings or the volumes can be linked forcomparison mode.

Study ReporterOutput selected views to create pre-defined, editable reports reducing the time tocomplete an exam and increasing departmental throughput.

Fully Integrated With Your RIS/PACS3Dnet™ DCE MRI Perfusion can be easily integrated into the RIS/PACS environment.



© Biotronics3D Ltd. 3DMR100217/A


CASE STUDYA 40 old female with breast cancer beforetreatment (Fig.1) and after 60 days ofchemotherapy treatment (Fig. 2).

Pharmacokinetics analysis using DCE MRIPerfusion was used to monitor a patient’sresponse to therapy. In this case, a substantial decrease in permeability can be seen by the kTrans maps and histograms as the patient positively responds to treatment.

Fig 1.

Fig 2.


PE T/ CT FUSIONPET/CT Fusion just got faster, easier, better with Study orientated workflows for faster and more accurate diagnoses through extensive, easy-to-use & cutting-edge tools for PET/CT visualization and analysis.

• Intuitive design allows for complete flexibility for PET/CT studies from tumour identification, assessment and followups in oncology through to diagnosis and monitoring of Alzheimer’s Disease in Neurology.

• Simple workflows matched with advanced visualisation and image registration provided for rapid reporting of studies.

• 3Dnet™ Suite PET/CT can be integrated seamlessly into the RIS/PACS environment.

Faster. 3Dnet™ Suite’s unique core design optimises memory and computer resource utilisation allowing for quickrendering of PET/CT image volumes.

Easier. 3Dnet™ Suite PET/CT is designed to adapt to doctors’ needs according to user profiles. As a result, the easy-to-use interface can be as feature-rich or as simple as desired.

Better. Fast rendering, image registration and hot spot identification, leading to faster turn-around times for tudy reporting.

PE T/ CT FUSION FEATURESBlending of PET and CT VolumesAdvanced blending of PET and CT volumes with independent W/L adjustment,andlinking between different planes of view.

Automated RegistrationAutomated rigid registration for scans from separate CT and PET studies with theability to manually correction misalignments.

Multiple and User-Configurable PET Colourmaps and CT PresetsA broad selection of commonly used PET colourmaps and CT presets for numerousstudy type from oncology to neurology studies.

SUV MeasurementConversion from BQML and the ability to update body mass if not predefined. Also SUVMax and SUV Av measurements in both 2D and 3D regions of interest.

Advanced Multi-Planar Reconstruction (MPR)Customisable MPR layouts with wide range of tools such as: obliques, doubleobliques, slabbing of images and auto-cineing of images in any plane.

Intuitive Measurements and AnnotationsCreate regions of interest in 2D Save lengths, diameters, angles, add text commentsand insert arrows.

Comparison ModeTwo datasets can be simultaneously on the same or seperate screens,allowing for comparison with prior studies. The datasets can be the same volume displayed at different settings or the volumes can be linked for comparison mode.

Customisable View LayoutsHighly customisable view layouts with supports for 2D, MPR and 3D with colourmapsbars ,alongside views which are exported as part of any image captures or reporting.

Integrated Workflow for ReportingPre-defined reports reducing the time to complete an exam and increase departmental through-put.

Fully Integrated With Your RIS/PACS3Dnet™ PET/CT Fusion can be easily integrated into the RIS/PACS environment.



© Biotronics3D Ltd. 3DPE100217/A



STENT GRAFT PLANNING

Faster, more detailed and accurate stent graft planning through a dedicated, easy-to-use application with cutting-edge tools for rapid, quantitative pre-surgical planning

• Fast, real time aneurysm measurement for procedure planning for thoracic and AAA stent grafts with diameter mapping for the entire length of the vessel.

• A dedicated workflow providing all the measurements required for stent graft planning. this is for the entire aortic and iliac tree with only four mouse clicks. • Vessel calcium and plaque analysis for identifying potential issues and landing sites for stents and grafts placement planning. • 3Dnet™ Graft Planning can be integrated seamlessly into any RIS/PACS environment.

Faster. 3Dnet™ Unique core design optimizes memory and computer resource utilization allowing for quick rendering of very large image volumes.

Easier. 3Dnet™ Graft Planning is designed to adapt to doctors’ needs according to user profiles. As a result,the easy-to-use interface can be as feature-rich or as users desire

Better. Template orientated reporting provides all of the information needed to complete graft component identification and ordering with complete confidence.

STENT GRAFT PLANNING FEATURESComplete Vascular Assessment and PlanningStent graft planning for thoracic and abdominal aortic aneurysms with curved MPR ,generating measurements required for graft components.

Advanced MeasurementsMeasurement markers are automatically generated so measurements for graft components are produced quickly.Dedicated displays for each marker displays the minimum and maximum diameter of the vessel and length from the selected baseline.

Fast Centreline Extraction with Synchronized Cross-Hair TrackingSimultaneous right and left iliac segmentation with rapid vessel segmentation and visualisation in any MPR view. This gives users the ability to navigate and track vessels without having to recalculate centrelines.

Pre-surgical Planning ReportingOne click report generation which provide all the relevant information for completing graft planning templates and component order forms.

Large Dataset SupportSupport for studies such as run-offs with more than 2500 slices.

One-click Bone RemovalQuick and easy bone removal and presets to localise vessels and vascular structures.

Calcification AnalysisHighlighting and segmentation of calcium deposits from contrast for accurate measurements and placement planning of devices.

Plaque AnalysisIdentify different types of plaques allowing for pre-procedure planning of the optimal type of device to use, placement and risk assessment.

Vessel SegmentationAutomatic vessel contour segmentation and with highlighted vessel view in highly detailed 3D views.

Cine ModeChoose between following the centreline, view-aligned (straight line forward or backward) or various rotations.

Fully Integrated With Your RIS/PACS3Dnet™ Graft Planning can be easily integrated into the RIS/PACS environment.


Biotronics3D Innovation Centre (BIC)Orwell House, CowleyRoad,Cambridge, CB4 0PP, UKT+44 (0) 1223 [email protected]© Biotronics3D Ltd. 3DSP100217/A


0344Recommended Recommended System Specifications:Dual Core Processor, Windows 7/Vista/XP2GB RAM, 200MB hard disk, standard graphics card

VASCULARFaster, more detailed and accurate diagnoses throughextensive, easy-to-use and cutting-edge tools forquantitative vessel analysis of CTA.

• Fast, real time stenosis and aneurysm measurement for procedure planning for stents, angioplasty and AAA endografts with diameter mapping the entire length of the vessel.

• Ability to show post-procedure scans in comparison mode to monitor any restenosis or movement of devices post placement.

• Vessel calcium and plaque analysis for identifying potential issues and landing sites for stents and endografts placement planning.

• 3Dnet™ Vascular can be integrated seamlessly into any RIS/PACS environment.

Faster. 3Dnet™unique core design optimizes memory and computer resource utilisation allowing forquick rendering of very large image volumes.

Easier. 3Dnet™ Vascular is designed to adapt to doctors’ needs according to user profiles. As a result, the easy-to-use interface can be as feature-rich or as simple as you like.

Better.Permits at-a-glance identification of anomalies that may correspond to aneurysms, calcifications and stenoses.

FEATURESComplete Vascular Assessment and Planning• Stent planning with stenosis measurement including minimum diameters and calcium segmentation.

• Stent graft planning for AAAs with curved MPR for generation of measurements required for graft components.

Study Comparison ModeFor simultaneous view of pre and post operative studies within the same screen or on dual monitors.

Large Dataset SupportSupport for studies such as run-offs with more than 2500 slices.

One-click Bone RemovalQuick and easy bone removal and presets to localise vessels and vascular structures.

Fast Centerline Extraction With Synchronized Cross-Hair TrackingProvides rapid vessel segmentation and visualisation in any MPR view to give usersability to navigate and track vessels.

One-click Vessel TrackingAllows for the identification of vascular structures and the growth of the vessel of interest.

Vessel segmentationAutomatic vessel contour segmentation and with highlighted vessel view in highlydetailed 3D views.

Calcification AnalysisHighlighting and segmentation of calcium deposits from contrast for accuratemeasurements and placement planning of devices.

Plaque AnalysisIdentify different types of plaques allowing for pre-procedure planning of the optimal type of device to use, placement and risk assessment.

Advanced MeasurementsPlots and displays the minimum and maximum diameter throughout and allows theuser to select a ‘normal’ section of the vessel as a baseline for comparison.Variances from the baseline are also displayed.

Measurement and Annotation ToolsA broad range of tools including length, diameters, angles, text comments andarrows for use in surgical planning as well as ordering of the correct components for surgery.

Cine ModeChoose between following the centerline, view-aligned (straight line forward orbackward) or various rotations.

Endoluminal FlythroughGenerate 3D flythroughs of vessels to visualise internal calcium deposits.

Fully Integrated With Your RIS/PACS3Dnet™ Vascular can be easily integrated into the RIS/PACS environment.



© Biotronics3D Ltd. 3DVS100217/A



3Dnet Suite Brochure

Documents

quantitative calcium

dnettm calcium scoring

rispacs3dnet calcium

calcium scoringcalcium

accurate assessment

volume scoring

max hu

quantitative reports