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28-y-o female with RLQ pain, nausea, low-grade fever, WBC Zissin R, Head of CT Meir Medical center
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28-y-o female with RLQ pain, nausea, low-grade fever, WBC Zissin R, Head of CT Meir Medical center.

Jan 11, 2016

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Page 1: 28-y-o female with RLQ pain, nausea, low-grade fever, WBC Zissin R, Head of CT Meir Medical center.

28-y-o female with RLQ pain, nausea, low-grade fever, WBC

Zissin R, Head of CT

Meir Medical center

Page 2: 28-y-o female with RLQ pain, nausea, low-grade fever, WBC Zissin R, Head of CT Meir Medical center.

Ac abd. pain - a diagnostic challenge

RLQ - DD• Acute appendicitis (AA)• Epiploic appendagiitis / Omental

infarction - non-surgical mimicker of AA

• GI related: Crohn’s disease (CD), Rt-sided diverticulitis, Inf. enteritis (Yersinia), Perforated cecal ca

• Mesenteric lymphadenitis • Acute GUT pathology:

Ac Pyelonephritis Renal colic

Gynecologic etiology

Page 3: 28-y-o female with RLQ pain, nausea, low-grade fever, WBC Zissin R, Head of CT Meir Medical center.

• The most common cause of RLQ pain and 28% of ac. abdominal pain

• Treated surgically !!! Perforation rate ~ 20%, (more common <9y and >60y)

• The most common emergency in children and pregnant women.

• 6% chance during lifetime for each person• Classic history: periumbilical pain

migrating to RLQ only in 50%, atypical presentation mainly children, women 20-40y, elderly

Acute appendicitis

Page 4: 28-y-o female with RLQ pain, nausea, low-grade fever, WBC Zissin R, Head of CT Meir Medical center.

Imaging modalities in acute abdomen

• Plain abdominal films: supine & erect – LIMITED INDICATIONS

• US – non invasive, no radiation• CT – semi invasive, radiation ! • Contrast media studies: imaging of

bowel only (barium, gastrografin) – radiation

Page 5: 28-y-o female with RLQ pain, nausea, low-grade fever, WBC Zissin R, Head of CT Meir Medical center.

Plain abdominal films - Indications:

1. Detection of free air: Common causes: perforation of hollow viscus, post-operation, peritoneal dialysis

2. Gas (air) distribution: intestinal obstruction – dilated loops, air/fluid levelsdisplaced loops – a secondary sign of mass effect

3. Detection of pathological calcificationsMost common: calculi (20% of gallstones; 80% urolithiasis), vascular, intra-abdominal radiopaque foreign bodies

• Usually insensitive in AA but can suggest an alternative diagnosis

Page 6: 28-y-o female with RLQ pain, nausea, low-grade fever, WBC Zissin R, Head of CT Meir Medical center.

Ultrasound

• Advantages: - Lack of radiation, non-expensive and availability

- Aids in diagnosing alternative causes• Disadvantages :

- Operator dependent !! - Sen 85-90%, Spec 92-96%,

As NPP is too low CT• Mainly in children & childbearing age

women

Page 7: 28-y-o female with RLQ pain, nausea, low-grade fever, WBC Zissin R, Head of CT Meir Medical center.

• Aperistaltic, noncompressible, blind-ended, fluid-filled, tubular structure with distinct wall layers arising from the cecal base

• Outer diameter > 6 mm • Appendicolith • Periappendiceal fluid

collection

Page 8: 28-y-o female with RLQ pain, nausea, low-grade fever, WBC Zissin R, Head of CT Meir Medical center.

Computed Tomography - CT

• Radiation! (excludes pregnancy, consider benefit versus radiation risk)

• Semi invasive exam. – IV injection of CM

Page 9: 28-y-o female with RLQ pain, nausea, low-grade fever, WBC Zissin R, Head of CT Meir Medical center.

19721972

-זהו מכשיר ה-זהו מכשיר הCTCT 19721972 הראשון בעולם משנת הראשון בעולם משנת : : ,ניתן היה לסרוק איתו רק את המח, ניתן היה לסרוק איתו רק את המח – רזולוציה נמוכהרזולוציה נמוכה,, דקות דקות 55זמן סריקת תמונה – זמן סריקת תמונה

Page 10: 28-y-o female with RLQ pain, nausea, low-grade fever, WBC Zissin R, Head of CT Meir Medical center.

20052005

התפתחות בחומרה ותוכנההתפתחות בחומרה ותוכנה -כיום מכשירי ה- כיום מכשירי הCTCT מסוגלים לסרוק את כל הגוף מסוגלים לסרוק את כל הגוף

תוך מספר שניות, במהירות גבוהה וברזולוציה תוך מספר שניות, במהירות גבוהה וברזולוציה מצוינת מצוינת

Page 11: 28-y-o female with RLQ pain, nausea, low-grade fever, WBC Zissin R, Head of CT Meir Medical center.

Type of CT examinations

• Diagnostic study• Interventional

procedure:- F. N. A (fine needle aspiration)

- Diagnostic puncture (bacteriological evaluation)

- Drainage of abscess, fluid collections

• Screening - Virtual colonoscopy- Cardiac CT- Low dose chest CT

Page 12: 28-y-o female with RLQ pain, nausea, low-grade fever, WBC Zissin R, Head of CT Meir Medical center.

Radiation on CT

• Abd CT (~ 500 CXR)(BE-350 CXR, Upper GIT-150 CXR)

• Typical effective dose 10mSv (time provide for equivalent effective dose from background radiation – 3.3y)

• Malignancy risk: 5%/1Sv 1 to 2000

Page 13: 28-y-o female with RLQ pain, nausea, low-grade fever, WBC Zissin R, Head of CT Meir Medical center.

Technical notes – Abdominal CT

• Optimal technique: Oral+IV Contrast Media - Oral (for maximum GIT opacification)

-IV (semi-invasive) ~120cc 2,5-4cc/sec

Optional: - Rectal - Cysto CT • Delayed scan as necessary

Page 14: 28-y-o female with RLQ pain, nausea, low-grade fever, WBC Zissin R, Head of CT Meir Medical center.

5 tissues

densities

Everything should be made as simple as possible, but not simpler.

Albert Einshtein

air ca++

fluidfat soft tissue

Page 15: 28-y-o female with RLQ pain, nausea, low-grade fever, WBC Zissin R, Head of CT Meir Medical center.

Acute Appendicitis• CT diagnosis depends on combined

appendicular and periappendicular signsCT sens. 94-97%; spec. 97-99%; accuracy 93-98%; NPV & PPV 94-98%

• Appendicular signs: distended (>6mm), unopacified thickened wall (>2mm) app. appendicolith

• Periappendicular signs: pericecal fat strandingscecal mural thickening-“arrowhead”

Page 16: 28-y-o female with RLQ pain, nausea, low-grade fever, WBC Zissin R, Head of CT Meir Medical center.

Periap. Abscess

Conservative therapy + P.C. abscess drainage > 3cm

Page 17: 28-y-o female with RLQ pain, nausea, low-grade fever, WBC Zissin R, Head of CT Meir Medical center.

Epiploic appendagitis

• Torsion of EA-infarction and sec. inflammatory changes

• Clinical presentation – L/RLQ signs of peritonitis, mimicking ac. diverticulitis/ appendicitis

• Benign, self-limited course

Page 18: 28-y-o female with RLQ pain, nausea, low-grade fever, WBC Zissin R, Head of CT Meir Medical center.

An oval-shaped fat density with a rim of soft-tissue density juxtaposed to the serosal colonic surface

Page 19: 28-y-o female with RLQ pain, nausea, low-grade fever, WBC Zissin R, Head of CT Meir Medical center.

Crohn’s Disease (CD) - terminal ileitis

• Diarrhea- most common presentation• Gradual, progressive RLQ pain - 45-95%• Role of CT:

In known cases - for detection of:- complications (abscess, enterovesical fistula, perianal disease)- alternative diagnosis (look for the appendix)

* CD may be first diagnosed on CT in pts. presented with acute abdomen – RLQ pain

Page 20: 28-y-o female with RLQ pain, nausea, low-grade fever, WBC Zissin R, Head of CT Meir Medical center.

CT in CD

• Direct imaging of the bowel wall (normal <3mm)

• Secondary signs in surrounding mesentery:-mesenteric vascular engorgement-fluid within the mesenteric root-peri-bowel fat stranding, ”creeping fat”-mesenteric adenopathy

• To guide P.C. interventional procedures

Page 21: 28-y-o female with RLQ pain, nausea, low-grade fever, WBC Zissin R, Head of CT Meir Medical center.

Stones and Obstruction

• Non contrast scan• Determine the level

of obstruction: calculi, and associated parenchymal changes

Page 22: 28-y-o female with RLQ pain, nausea, low-grade fever, WBC Zissin R, Head of CT Meir Medical center.
Page 23: 28-y-o female with RLQ pain, nausea, low-grade fever, WBC Zissin R, Head of CT Meir Medical center.

GOOD LUCKGOOD LUCK