Page 1
Page 1 of 5SWGDRUG.org/monographs.htmLatest Revision: 8/10/2017
Testosterone CaproateThe Drug Enforcement Administration's Special Testing and Research Laboratory
generated this monograph using structurally confirmed reference material.
1. GENERAL INFORMATION
IUPAC Name: (17)-3-oxoandrost-4-en-17-yl hexanoate
CAS#: 10312-45-5
Synonyms: Testosterone Hexanoate
Source: DEA Reference Material Collection
Appearance: White powder
UVmax(nm): Not Determined
2. CHEMICAL AND PHYSICAL DATA
2.1 CHEMICAL DATA
Form Chemical Formula Molecular Weight Melting Point (oC)
Base C25H38O3 386.57 42.9
O
O
O
CH3
CH3CH3
H
H H
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Page 2 of 5SWGDRUG.org/monographs.htmLatest Revision: 8/10/2017
Testosterone CaproateThe Drug Enforcement Administration's Special Testing and Research Laboratory
generated this monograph using structurally confirmed reference material.
3. QUALITATIVE DATA
3.1 NUCLEAR MAGNETIC RESONANCE
Sample Preparation: Dilute analyte to ~5 mg/mL in CD3OD containing TMS for 0 ppm reference and dimethylfumarate as quantitative internal standard.
Instrument: 400 MHz NMR spectrometerParameters: Spectral width: at least containing -3 ppm through 13 ppm
Pulse angle: 90o
Delay between pulses: 45 seconds1HNMR: Testosterone Caproate; Lot# RM-161213-01; CD3OD; 400MHz
7 6 5 4 3 2 1 0
0
1
2
3
4
5
6
7
8
9
10
63414124211
From CD3OD From CD3OD TMSDimethylfumarate
4.65
1
5.75
1
1.225
4
2.50
2
1.10 1.00
3
2.35
4
1.50
14
0.900
6
2.15
2
1.900
1
Dimethylfumarate
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Page 3 of 5SWGDRUG.org/monographs.htmLatest Revision: 8/10/2017
Testosterone CaproateThe Drug Enforcement Administration's Special Testing and Research Laboratory
generated this monograph using structurally confirmed reference material.
3.2 GAS CHROMATOGRAPHY/MASS SPECTROMETRY
Sample Preparation: Dilute analyte ~4 mg/mL in Methanol.
Instrument: Agilent gas chromatograph operated in split mode with MS detectorColumn: HP-5 MS (or equivalent); 30m x 0.25 mm x 0.25mCarrier Gas: Helium at 1.5 mL/minTemperatures: Injector: 280oC
MSD transfer line: 280oCMS Source: 230oCMS Quad: 150oCOven program:
1) 100oC initial temperature for 1.0 min2) Ramp to 280oC at 12 oC/min3) Hold final temperature for 9.0 min
Injection Parameters: Split Ratio = 25:1, 1 L injectedMS Parameters: Mass scan range: 30-550 amu
Threshold: 100Tune file: stune.uAcquisition mode: scan
Retention Time: 22.190 minEI Mass Spectrum: Testosterone Caproate; Lot # RM-161213-01
m/z35030025020015010050
[x 1
05 ]In
tens
ity
0.5
1.0
1.5
386
386
386
386
386
386
386
386
386
386
386
386
386
386
386
386
386
386
386
386
386
386
371
371
371
371
371
371
371
371
371
371
371
371
371
371
371
371
371
371
371
371
371
371
358
358
358
358
358
358
358
358
358
358
358
358
358
358
358
358
358
358
358
358
358
35834
434
434
434
434
434
434
434
434
434
434
434
434
434
434
434
434
434
434
434
434
434
4
326
326
326
326
326
326
326
326
326
326
326
326
326
326
326
326
326
326
326
326
326
326301
301
301
301
301
301
301
301
301
301
301
301
301
301
301
301
301
301
301
301
301
30128
828
828
828
828
828
828
828
828
828
828
828
828
828
828
828
828
828
828
828
828
828
8
270
270
270
270
270
270
270
270
270
270
270
270
270
270
270
270
270
270
270
270
270
270
255
255
255
255
255
255
255
255
255
255
255
255
255
255
255
255
255
255
255
255
255
255
245
245
245
245
245
245
245
245
245
245
245
245
245
245
245
245
245
245
245
245
245
245
228
228
228
228
228
228
228
228
228
228
228
228
228
228
228
228
228
228
228
228
228
228
213
213
213
213
213
213
213
213
213
213
213
213
213
213
213
213
213
213
213
213
213
213
199
199
199
199
199
199
199
199
199
199
199
199
199
199
199
199
199
199
199
199
199
19918
518
518
518
518
518
518
518
518
518
518
518
518
518
518
518
518
518
518
518
518
518
517
317
317
317
317
317
317
317
317
317
317
317
317
317
317
317
317
317
317
317
317
317
3159
159
159
159
159
159
159
159
159
159
159
159
159
159
159
159
159
159
159
159
159
159
147
147
147
147
147
147
147
147
147
147
147
147
147
147
147
147
147
147
147
147
147
147
124
124
124
124
124
124
124
124
124
124
124
124
124
124
124
124
124
124
124
124
124
124
999999 9999999999 9999999999 9999999999 99999999919191 9191919191 9191919191 9191919191 91919191
797979 7979797979 7979797979 7979797979 79797979717171 7171717171 7171717171 7171717171 71717171
555555 5555555555 5555555555 5555555555 55555555434343 4343434343 4343434343 4343434343 43434343
m/z35030025020015010050
[x 1
04 ]In
tens
ity
386
386
386
386
386
386
386
386
386
386
386
386
386
386
386
386
386
386
386
386
386
386
371
371
371
371
371
371
371
371
371
371
371
371
371
371
371
371
371
371
371
371
371
371
358
358
358
358
358
358
358
358
358
358
358
358
358
358
358
358
358
358
358
358
358
358
344
344
344
344
344
344
344
344
344
344
344
344
344
344
344
344
344
344
344
344
344
344
326
326
326
326
326
326
326
326
326
326
326
326
326
326
326
326
326
326
326
326
326
326
301
301
301
301
301
301
301
301
301
301
301
301
301
301
301
301
301
301
301
301
301
301
288
288
288
288
288
288
288
288
288
288
288
288
288
288
288
288
288
288
288
288
288
288
270
270
270
270
270
270
270
270
270
270
270
270
270
270
270
270
270
270
270
270
270
270
255
255
255
255
255
255
255
255
255
255
255
255
255
255
255
255
255
255
255
255
255
255245
245
245
245
245
245
245
245
245
245
245
245
245
245
245
245
245
245
245
245
245
245
228
228
228
228
228
228
228
228
228
228
228
228
228
228
228
228
228
228
228
228
228
228
213
213
213
213
213
213
213
213
213
213
213
213
213
213
213
213
213
213
213
213
213
213
199
199
199
199
199
199
199
199
199
199
199
199
199
199
199
199
199
199
199
199
199
199
185
185
185
185
185
185
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185
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185
185
185
185
185
185
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185
173
173
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173
173
17315
915
915
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915
915
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915
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915
915
915
915
915
915
915
915
915
915
914
714
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714
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714
714
714
714
714
714
714
714
714
714
714
7
124
124
124
124
124
124
124
124
124
124
124
124
124
124
124
124
124
124
124
124
124
124
999999 9999999999 9999999999 9999999999 99999999919191 9191919191 9191919191 9191919191 91919191797979 7979797979 7979797979 7979797979 79797979717171 7171717171 7171717171 7171717171 71717171555555 5555555555 5555555555 5555555555 55555555434343 4343434343 4343434343 4343434343 43434343
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Page 4 of 5SWGDRUG.org/monographs.htmLatest Revision: 8/10/2017
Testosterone CaproateThe Drug Enforcement Administration's Special Testing and Research Laboratory
generated this monograph using structurally confirmed reference material.
3.3 INFRARED SPECTROSCOPY (FTIR)
Insrument: FTIR with diamond ATR attachment (1 bounce)Scan Parameters: Number of scans: 32
Number of background scans: 32Resolution: 4 cm-1
Sample gain: 1Aperture: 150
FTIR ATR (Diamond 1 Bounce): Testosterone Caproate; Lot # RM-161213-01
Wavenumber (cm-1)3500 3000 2500 2000 1500
%Tr
ansm
ittan
ce
30
40
50
60
70
2929292929292929292929292929292929292929292929292929292929292929292929292929292929292929
2848284828482848284828482848284828482848284828482848284828482848284828482848284828482848
1725172517251725172517251725172517251725172517251725172517251725172517251725172517251725 1664
166416641664166416641664166416641664166416641664166416641664166416641664166416641664
1617161716171617161716171617161716171617161716171617161716171617161716171617161716171617
1442144214421442144214421442144214421442144214421442144214421442144214421442144214421442 1379
137913791379137913791379137913791379137913791379137913791379137913791379137913791379
1351135113511351135113511351135113511351135113511351135113511351135113511351135113511351 1228
122812281228122812281228122812281228122812281228122812281228122812281228122812281228
1181118111811181118111811181118111811181118111811181118111811181118111811181118111811181
11171117111711171117111711171117111711171117111711171117111711171117111711171117111711171039103910391039103910391039103910391039103910391039103910391039103910391039103910391039
969969969969969969969969969969969969969969969969969969969969969969
942942942942942942942942942942942942942942942942942942942942942942
864864864864864864864864864864864864864864864864864864864864864864
776776776776776776776776776776776776776776776776776776776776776776733733733733733733733733733733733733733733733733733733733733733733687687687687687687687687687687687687687687687687687687687687687687
574574574574574574574574574574574574574574574574574574574574574574 508
508508508508508508508508508508508508508508508508508508508508508
Wavenumber (cm-1)1700 1600 1500 1400 1300 1200 1100 1000 900 800 700
%Tr
ansm
ittan
ce
30
40
50
60
70
1725172517251725172517251725172517251725172517251725172517251725172517251725172517251725 1664
166416641664166416641664166416641664166416641664166416641664166416641664166416641664
1617161716171617161716171617161716171617161716171617161716171617161716171617161716171617
1442144214421442144214421442144214421442144214421442144214421442144214421442144214421442 1379
137913791379137913791379137913791379137913791379137913791379137913791379137913791379
1351135113511351135113511351135113511351135113511351135113511351135113511351135113511351
1309130913091309130913091309130913091309130913091309130913091309130913091309130913091309
1240124012401240124012401240124012401240124012401240124012401240124012401240124012401240 1228
122812281228122812281228122812281228122812281228122812281228122812281228122812281228
1181118111811181118111811181118111811181118111811181118111811181118111811181118111811181
1117111711171117111711171117111711171117111711171117111711171117111711171117111711171117
10391039103910391039103910391039103910391039103910391039103910391039103910391039103910391004100410041004100410041004100410041004100410041004100410041004100410041004100410041004
969969969969969969969969969969969969969969969969969969969969969969
942942942942942942942942942942942942942942942942942942942942942942
864864864864864864864864864864864864864864864864864864864864864864
776776776776776776776776776776776776776776776776776776776776776776733733733733733733733733733733733733733733733733733733733733733733687687687687687687687687687687687687687687687687687687687687687687
574574574574574574574574574574574574574574574574574574574574574574 508
508508508508508508508508508508508508508508508508508508508508508
Page 5
Page 5 of 5SWGDRUG.org/monographs.htmLatest Revision: 8/10/2017
Testosterone CaproateThe Drug Enforcement Administration's Special Testing and Research Laboratory
generated this monograph using structurally confirmed reference material.
https://en.wikipedia.org/wiki/Testosterone_caproate
4. ADDITIONAL RESOURCES
Wikipedia