2019 年度業績 東京医科⻭科⼤学⼤学院 脳神経病態学(神経内科)分野 【原著】 1. Ishibashi T, Toyama S, Miki K, Karakama J, Yoshino Y, Ishibashi S, Tomita M, Nemoto S. Effects of propofol versus sevoflurane on cerebral circulation time in patients uandergoing coiling for cerebral artery aneurysm: a prospective randomized crossover study. Journal of Clinical monitoring and computing.2019.01;33(6);987-998. 2. Amano E, Ozaki K, Ishibashi S, Sanjo N, Yokota T. Remarkable improvement in progressive multifocal leukoencephalopathy following acute pyelonephritis with bacteremia. Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia. 2019.01; 62; 226-228. 3. Takahashi K, Yanai S, Takisawa S, Kono N, Arai H, Nishida Y, Yokota T, Endo S, Ishigami A. Vitamin C and vitamin E double-deficiency increased neuroinflammation and impaired conditioned fear memory.Archives of biochemistry and biophysics. 2019.01; 663; 120-128. 4. Maeda Y, Iwata Hara R, Nishina K, Yoshida-Tanaka K, Sakamoto T, Yokota T, Wada T. Artificial cationic peptides that increase nuclease resistance of siRNA without disturbing RNAi activity. Nucleosides, nucleotides & nucleic acids. 2019.01; 38(5); 338-348. 5. Suzuki S, Naito S, Numasawa Y, Asada M, Shoji N, Zeniya M, Takahashi D, Sato H, Iimori S, Nomura N, Sohara E, Okado T, Ishiwata Y, Nagata M, Rai T, Yokota T, Uchida S. Encephalopathy Induced by High Plasma and Cerebrospinal Fluid Ceftriaxone Concentrations in a Hemodialysis Patient. Internal medicine(Tokyo, Japan). 2019.02;58(12):1775-1779. 6. Yokote H., Amano R., Toru S., Hattori T., Nishida Y., Sanjo N., Yokota T.. Brain Atrophy is Associated with Higher Serum Amyloid A Levels in Patients with Relapsing and Remitting Multiple Sclerosis and Clinically Isolated Syndrome MULTIPLE SCLEROSIS JOURNAL. 2019.03; 25(3); 442.
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2019 年度業績
東京医科⻭科⼤学⼤学院 脳神経病態学(神経内科)分野
【原著】 1. Ishibashi T, Toyama S, Miki K, Karakama J, Yoshino Y, Ishibashi S, Tomita M, Nemoto S. Effects of propofol versus sevoflurane on cerebral circulation time in patients uandergoing coiling for cerebral artery aneurysm: a prospective randomized crossover study. Journal of Clinical monitoring and computing.2019.01;33(6);987-998. 2. Amano E, Ozaki K, Ishibashi S, Sanjo N, Yokota T. Remarkable improvement in progressive multifocal leukoencephalopathy following acute pyelonephritis with bacteremia. Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia. 2019.01; 62; 226-228. 3. Takahashi K, Yanai S, Takisawa S, Kono N, Arai H, Nishida Y, Yokota T, Endo S, Ishigami A. Vitamin C and vitamin E double-deficiency increased neuroinflammation and impaired conditioned fear memory.Archives of biochemistry and biophysics. 2019.01; 663; 120-128. 4. Maeda Y, Iwata Hara R, Nishina K, Yoshida-Tanaka K, Sakamoto T, Yokota T, Wada T. Artificial cationic peptides that increase nuclease resistance of siRNA without disturbing RNAi activity. Nucleosides, nucleotides & nucleic acids. 2019.01; 38(5); 338-348. 5. Suzuki S, Naito S, Numasawa Y, Asada M, Shoji N, Zeniya M, Takahashi D, Sato H, Iimori S, Nomura N, Sohara E, Okado T, Ishiwata Y, Nagata M, Rai T, Yokota T, Uchida S. Encephalopathy Induced by High Plasma and Cerebrospinal Fluid Ceftriaxone Concentrations in a Hemodialysis Patient. Internal medicine(Tokyo, Japan). 2019.02;58(12):1775-1779. 6. Yokote H., Amano R., Toru S., Hattori T., Nishida Y., Sanjo N., Yokota T.. Brain Atrophy is Associated with Higher Serum Amyloid A Levels in Patients with Relapsing and Remitting Multiple Sclerosis and Clinically Isolated Syndrome MULTIPLE SCLEROSIS JOURNAL. 2019.03; 25(3); 442.
7. Furukawa F, Ishikawa K, Yokota T, Sanjo N. Cross-Sectional Area Analysis of the Head of the Caudate Nucleus in Huntingtonʼs Disease. European neurology. 2019.04; 81(1-2); 13-18. 8. Ebashi M, Toru S, Nakamura A, Kamei S, Yokota T, Hirokawa K, Uchihara T. Detection of AD-specific four repeat tau with deamidated asparagine residue 279-specific fraction purified from 4R tau polyclonal antibody. Acta neuropathologica. 2019.04; 138(1); 163-166. 9. Hashimoto S, Inaji M, Nariai T, Kobayashi D, Sanjo N, Yokota T, Ishii K, Taketoshi M. Usefulness of [11 C] Methionine PET in the Differentiation of Tumefactive Multiple Sclerosis from High Grade Astrocytoma. Neurologia medico-chirurgica. 2019.04; 59(5); 176-183. 10. Rashaun S. Wilson, Navin Rauniyar, Fumika Sakaue, TuKiet T. Lam, Kenneth R. Williams, Angus C. Nairn. Development of Targeted Mass Spectrometry-Based Approaches for Quantitation of Proteins Enriched in the Postsynaptic Density (PSD) proteomes. 2019.04; 7(2);12. 11. Nico J. Diedrich, James Surmeier, Toshiki Uchihara, Sten Grillner, Christopher G. Goetz. Parkinsonʼs disease: Is it a consequence of human brain evolution? Movement Disorders. 2019.04; 34(4); 453-1531. 12. Guo L, Bertola DR, Takanohashi A, Saito A, Segawa Y, Yokota T, Ishibashi S, Nishida Y, Yamamoto GL, Franco JFDS, Honjo RS, Kim CA, Musso CM, Timmons M, Pizzino A, Taft RJ, Lajoie B, Knight MA, Fischbeck KH, Singleton AB, Ferreira CR, Wang Z, Yan L, Garbern JY, Simsek-Kiper PO, Ohashi H, Robey PG, Boyde A, Matsumoto N, Miyake N, Spranger J, Schiffmann R, Vanderver A, Nishimura G, Passos-Bueno MRDS, Simons C, Ishikawa K, Ikegawa S. Bi-allelic CSF1R Mutations Cause Skeletal Dysplasia of Dysosteosclerosis-Pyle Disease Spectrum and Degenerative Encephalopathy with Brain Malformation. American journal of human genetics. 2019.05; 104(5); 925-935. 13. Uehara T, Choong CJ, Nakamori M, Hayakawa H, Nishiyama K, Kasahara Y, Baba K, Nagata T, Yokota T, Tsuda H, Obika S, Mochizuki H. Amido-bridged nucleic acid (AmNA)-modified antisense oligonucleotides targeting α-synuclein as a novel therapy for Parkinsonʼs disease. Scientific reports. 2019.05;9(1); 7567. 14. Ozaki K, Ansai A, Nobuhara K, Araki T, Kubodera T, Ishii T, Higashi M, Sato N, Soga
K, Mizusawa H, Ishikawa K, Yokota T. Prevalence and clinicoradiological features of spinocerebellar ataxia type 34 in a Japanese ataxia cohort. Parkinsonism & related disorders. 2019.05; 65; 238-242. 15. Otsu S, Ishibashi S, Ozaki K, Yokota T. Elevated lipid peaks during the recovery phase of Balóʼs concentric sclerosis: A case report. eNeurologicalSci. 2019.06; 15; 100191. 16. Ono D, Shishido-Hara Y, Mizutani S, Mori Y, Ichinose K, Watanabe M, Tanizawa T, Yokota T, Uchihara T, Fujigasaki H. Development of demyelinating lesions in progressive multifocal leukoencephalopathy (PML): Comparison of magnetic resonance images and neuropathology of post-mortem brain. Neuropathology: official journal of the Japanese Society of Neuropathology. 2019.06; 39(4); 294-306. 17. Hashiguchi S, Doi H, Kunii M, Nakamura Y, Shimuta M, Suzuki E, Koyano S, Okubo M, Kishida H, Shiina M, Ogata K, Hirashima F, Inoue Y, Kubota S, Hayashi N, Nakamura H, Takahashi K, Katsumoto A, Tada M, Tanaka K, Sasaoka T, Miyatake S, Miyake N, Saitsu H, Sato N, Ozaki K, Ohta K, Yokota T, Mizusawa H, Mitsui J, Ishiura H, Yoshimura J, Morishita S, Tsuji S, Takeuchi H, Ishikawa K, Matsumoto N, Ishikawa T, Tanaka F. Ataxic phenotype with altered CaV3.1 channel property in amouse model for spinocerebellar ataxia 42. Neurobiology of disease. 2019.06; 130; 104516. 18. Rintaro Iwata Hara, Tatsuya Saito, Tomoki Kogure, Yuka Hamamura, Naoki Uchiyama, Yohei Nukaga, Naoki Iwamoto,Takeshi Wada. Stereocontrolled Synthesis of Boranophosphate DNA by an Oxazaphospholidine Approach and Evaluation of Its Properties Journal of Organic Chemistry. 2019.06; 84(12);7971-7983. 19. ⽯橋 智⼦, 遠⼭ 悟史, 三⽊ ⼀徳, 唐鎌 淳, 吉野 義⼀, ⽯橋 哲, 冨⽥ 誠, 槇⽥ 浩史, 根本 繁. 全⾝⿇酔薬の種類による前⽅循環の各分枝の循環時間の⽐較 臨床薬理の進歩. 2019.06; (40); 199-206. 20. 内原俊記、融衆太. Controversy α シヌクレインの伝播をとめればパーキンソン病を根治できるかー No の⽴場からー MDSJ Letters. 2019.06; 12(1); 1-3. 21. Fujita K, Tanaka K, Yamagami H, Ide T, Ishiyama H, Sonoda K, Satow T, Takahashi JC, Ihara M, Koga M, Yokota T, Toyoda K. Detrimental Effect of Chronic Hypertension on Leptomeningeal Collateral Flow in Acute Ischemic Stroke. Stroke. 2019.07; 50(7); 1751-1757.
22. Nishida Y, Takahashi YK, Kanai T, Nose Y, Ishibashi S, Sanjo N, Uzawa A, Oda F, Ozawa Y, Kuwabara S, Noguchi E, Suzuki S, Nakahara J, Suzuki N, Ogawa T, Yokoyama K, Hattori N, Konno S, Fujioka T, Kawaguchi N, Hatanaka Y, Sonoo M, Kaneko J, Ogino M, Nishiyama K, Nomura K, Yokota T. Safety of tapering tacrolimus dose in patients with well-controlled anti-acetylcholine receptor antibody-positive myasthenia gravis. European journal of neurology. 2019.07; 27(1); 100-104. 23. Shintaku H, Yamaguchi M, Toru S, Kitagawa M, Hirokawa K, Yokota T, Uchihara T. Three-dimensional surface models of autopsied human brains constructed from multiple photographs by photogrammetry.PLoS One. 2019.07; 14(7); e0219619. 24. Momoko Ebashi, Shuta Toru, Ayako Nakamura, Satoshi Kamei, Takanori Yokota, Katsuiku Hirokawa, Toshiki Uchihara. Detection of AD-specific four repeat tau with deamidated asparagine residue 279-specific fraction purified from 4R tau polyclonal antibody Acta Neuropathologica. 2019.07; 138(1); 163-166. 25. Yoshioka K, Kunieda T, Asami Y, Guo H, Miyata H, Yoshida-Tanaka K, Sujino Y, Piao W, Kuwahara H, Nishina K, Hara RI, Nagata T, Wada T, Obika S, Yokota T. Highly efficient silencing of microRNA by heteroduplex oligonucleotides. Nucleic acids research. 2019.08; 47(14); 7321-7332. 26. Ohara M, Sanjo N, Hattori T, Oyama J, Hamada M, Ozaki K, Yokota T. Olivary hypertrophy improved by steroid treatment: Two case reports with unique presentations. Journal of neuroimmunology. 2019.09;334; 577003. 27. Yanagidaira M, Hattori T, Emoto H, Kiyosawa M, Yokota T. Optic perineuritis with anti-myelin oligodendrocyte glycoprotein antibody. Multiple sclerosis and related disorders. 2019.10; 38; 101444. 28. Kazuki Sato , Hiroki Imai , Tomohito Shuto , Rintaro Iwata Hara , Takeshi Wada. Solid-Phase Synthesis of Phosphate/Boranophosphate Chimeric DNAs using the H-Phosphonate‒H-Boranophosphonate Method Journal of Organic Chemistry. 2019.10; 84(23); 15032-15041. 29. Kobayashi Z, Ishibashi S, Numasawa Y, Shintani S. Practical guide to choosing dabigatran 150 mg twice daily or apixaban 5 mg twice daily for patients with atrial fibrillation.
Journal of rural medicine : JRM. 2019.11; 14(2); 153-155. 30. Ohyagi Masaki, Irioka Takashi, Ohkubo Takuya, Ishibashi Satoru, Takahashi Yuko K, Amano Eiichiro, Machida Akira, Kuwahara Hiroya, Yokota Takanori. Intrathecal IgG Synthesis and Persistent Inflammation Are Associated with White Matter Lesions in HIV-negative Patients with Cryptococcal Meningoencephalitis Internal Medicine. 2019.11; 58(21); 3077-3082. 31. Hirata K, Kobayashi M, Miyashita A, Yokota T. Steroid-responsive myositis in a patient with Sjögren's syndrome and refractory peripheral neuropathy. Neurological Sciences: official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology. 2019.12; 41(5); 1303-1305. 32. Yanagidaira M, Nishida Y, Yokota T. Temporal correlation between serum CH50 level and symptom severity of myasthenia gravis during eculizumab therapy. Clinical neurology and neurosurgery. 2019.12; 189; 105630. 33. 坂本路果, 岩瀬遼, ⽯⿊太郎, ⼋⽊洋輔, ⽯橋哲, 三條伸夫, 横⽥隆徳. ⽚側上肢筋⼒低下で発症し、8 年後に難聴を来した脳表ヘモジデリン沈着症の 1 例臨床神経学. 2020.01; 60(1); 83 34. Lei Mon SS, Yoshioka K, Jia C, Kunieda T, Asami Y, Yoshida-Tanaka K, Piao W, Kuwahara H, Nishina K, Nagata T, Yokota T. Highly efficient gene silencing in mouse brain by overhanging-duplex oligonucleotides via intraventricular route. FEBS letters. 2020.01; 35. Teruhiko Sekiguchi, Satoru Ishibashi, Jo Sasame, Jun-Ichi Mukae, Kotaro Noda, Hiroaki Tanaka, Koh Yamamoto, Yasunori Takemoto, Jiro Kumagai, Takanori Yokota. Recurrent stroke due to quasi-moyamoya disease associated with POEMS syndrome: An autopsy case. J. Neurol. Sci.. 2020.02; 412; 116738 36. Tai Otani, Takashi Irioka, Susumu Igarashi, Kimihiko Kaneko, Toshiyuki Takahashi, Takanori Yokota. Self-remitting cerebral cortical encephalitis associated with myelin oligodendrocyte glycoprotein antibody mimicking acute viral encephalitis: A case report. Mult Scler Relat Disord. 2020.02; 41; 102033 37. Kosei Hirata, Takaaki Hattori, Satoko Kina, Qingmeng Chen, Masahiro Ohara,