Page 1
2014 Molecular CPT Coding with Palmetto PTI codes
UPDATED 10/01/2014
The CPT codes provided are based on AMA guidelines and are for informational purposes only. CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the
Quest Diagnostics Test Name
Quest Diagnostics Order Code 2014 CPT Codes Palmetto PTI
19911A>G Mutation Analysis 16533(X) 81400 PBF19
19911A>G Mutation Analysis (NY) 16534(X) 81400 PBF19
ABL Kinase Domain Mutation in CML, Cell-based 16029(X) 81403 PBC33
ABL Kinase Domain Mutation in CML, Plasma-based, Leumeta(R) 16031(X) 81403 PBC33
ABL T315I Mutation in CML, Cell-based 19783(X) 81401 PBC34
ABL T315I Mutation in CML, Plasma-based, Leumeta(R) 19782(X) 81401 PBC34
AccuType(R) IL28B 90251(X) 81400 PB648
AccuType(R) IL28B (NY) 90252(X) 81400 PB648
AccuType(R) CP, Clopidogrel CYP2C19 Genotype 16924(X) 81225 PBE76
AccuType(R) CP, Clopidogrel CYP2C19 Genotype (NY) 16925(X) 81225 PBE76
AccuType(R) Warfarin 16160(X) 81355, 81227 PBE78
AccuType(R) Warfarin (NY) 16161(X) 81355, 81227 PBE78
Achondroplasia Mutation Analysis 16061(X) 81401 PBE79
Achondroplasia Mutation Analysis (NY) 16062(X) 81401 PBE79
payor being billed.
Page 2
2014 Molecular CPT Coding with Palmetto PTI codes UPDATED 10/01/2014
The CPT codes provided are based on AMA guidelines and are for informational purposes only. CPT
Quest Diagnostics Test Name
Quest Diagnostics Order Code 2014 CPT Codes Palmetto PTI
Acute Myeloid Leukemia Prognostic Panel (normal karyotype) 90871(X)
81403, 81310, 81245, 81479
PBC59, PBC43, PBC93
Acute Myeloid Leukemia Prognostic Panel (normal karyotype) (NY) 91867(X)
81403, 81310, 81245, 81479
PBC59, PBC43, PBC93
Admark ApoE Genotype Analysis 10642(X) 81401 PB870
Alpha-1 Antitrypsin (AAT) Mutation Analysis 15340(X) 81332 PB633
Alpha-1 Antitrypsin (AAT) Mutation AnalysisN (NY) 15341(X) 81332 PB633
Alpha-1-Antitrypsin (AAT) Quantitation and Mutation Analysis 17307(X) 81332, 82103 PB634
Alpha-1-Antitrypsin (AAT) Quantitation and Mutation Analysis (NY) 17313(X) 81332, 82103 PB634
Alpha-Globin Common Mutation Analysis 11175(X) 81257 PB739
Alpha-Globin Common Mutation Analysis (NY) 11174(X) 81257 PB739
Alpha-Globin Common Mutation Analysis, Fetus 91711(X) 81257 PB739
Alpha-Globin Gene Sequencing 16116(X) 81405 PBF01
Alpha-Globin Gene Sequencing (NY) 16117(X) 81405 PBF01
Alpha-Globin Gene Deletion or Duplication 16124(X) 81404 PBE80
Alpha-Globin Gene Deletion or Duplication (NY) 16125(X) 81404 PBE80
AML1/ETO t(8;21) Quantitative Real-Time PCR 14995(X) 81401 PB946
coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payor being billed.
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2014 Molecular CPT Coding with Palmetto PTI codes UPDATED 10/01/2014
The CPT codes provided are based on AMA guidelines and are for informational purposes only. CPT
Quest Diagnostics Test Name
Quest Diagnostics Order Code 2014 CPT Codes Palmetto PTI
Amyloidosis Evaluation 14759(X) 81479 PBG03
Angiotensin Converting Enzyme (ACE) Polymorphism (Insertion/Deletion) 11210(X) 81400 PBF41
Angiotensin Converting Enzyme (ACE) Polymorphism (Insertion/Deletion) (NY) 11211(X) 81400 PBF41
Angiotensin II Type 1 Receptor (AGTR1) Gene 1166A>C Polymorphism 11118(X) 81400 PBF42
Angiotensin II Type 1 Receptor (AGTR1) Gene 1166A>C Polymorphism (NY) 11242(X) 81400 PBF42
APC Gene Deletion or Duplication 16930(X) 81203 PBF43
APC Gene Sequencing 16934(X) 81201 PBF44
Ashkenazi Jewish Panel (4 tests) 90994(X)
81220 (CF), 81255 (TAY SACHS), 81200 (CANAVAN), 81260 (FAMILIAL DYS) PBG42
Ashkenazi Jewish Panel (11 Tests) 90891(X)
81220 (CF), 81200 (CANAVAN), 81251 (GAUCHER), 81242 (FANCONI), 81209 (BLOOM), 81255 (TAY SACHS), 81260 (FAMILIAL DYS), 81330 (NEIMANN PICK), 81290 (MUCOLILPIDOSIS), 81250 (GLYCOGEN STORAGE), 81205 (MAPLE SYRUP) PBG41
coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payor being billed.
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2014 Molecular CPT Coding with Palmetto PTI codes UPDATED 10/01/2014
The CPT codes provided are based on AMA guidelines and are for informational purposes only. CPT
Quest Diagnostics Test Name
Quest Diagnostics Order Code 2014 CPT Codes Palmetto PTI
Ashkenazi Jewish Panel (11 Tests) (NY) 90892(X)
81220 (CF), 81200 (CANAVAN), 81251 (GAUCHER), 81242 (FANCONI), 81209 (BLOOM), 81255 (TAY SACHS), 81260 (FAMILIAL DYS), 81330 (NEIMANN PICK), 81290 (MUCOLILPIDOSIS), 81250 (GLYCOGEN STORAGE), 81205 (MAPLE SYRUP) PBG41
B-Cell Gene Rearrangement, Qualitative PCR, Cell-based 14868(X) 81261 PBC36
B-Cell Gene Rearrangement, Qualitative PCR, Plasma-based, Leumeta(R) 16119(X) 81261 PBC36
B-cell Receptor IGH Gene Rearrangement, PCR (includes Pathologist interpretation) 90362(X)
81261, 84999 (HCPCS: G0452) PBZB9
B-cell Receptor IGK Gene Rearrangement, PCR (includes Pathologist interpretation) 90363(X)
81264, 84999 (HCPCS: G0452) PBZC1
B-cell Clonality Panel (IGH, IGK), PCR 91635(X)
81261, 81264, 84999 (HCPCS: G0452) PBZB9, PBZC1
BCR-ABL1 Gene Rearrangement, Quantitative PCR (includes BCRABL1/ ABL1 * P190 BCR-ABL1 * P210 BCR-ABL1) 91065(X)
81206 and/or 81207
PBAAB and/ or PBAAA
BCR-ABL1 Kinase Domain Mutation, 35-Nucleotide Insertion 16876(X) 81403 PBC61
Beta2-Adrenergic Receptor Mutations 16176(X) 81401 PBF80
coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payor being billed.
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2014 Molecular CPT Coding with Palmetto PTI codes UPDATED 10/01/2014
The CPT codes provided are based on AMA guidelines and are for informational purposes only. CPT
Quest Diagnostics Test Name
Quest Diagnostics Order Code 2014 CPT Codes Palmetto PTI
Beta2-Adrenergic Receptor Mutations (NY) 16177(X) 81401 PBF80
Beta-fibrinogen -455G>A Mutation 16182(X) 81400 PBF18
Beta-fibrinogen -455G>A Mutation (NY) 16183(X) 81400 PBF18
Beta-Globin Complete 14974(X) 81404 PBE81
Beta-Globin Complete (NY) 14979(X) 81404 PBE81
Beta-Globin Complete, Fetus 91709(X) 81404 PBE81
Beta Globin Gene Dosage Analysis 16346(X) 81403 PBF17
Beta Globin Gene Dosage Analysis (NY) 16347(X) 81403 PBF17
Cardio IQ(R) KIF6 Genotype 90645(X) 81479 PBD23
Cardio IQ(R) LPA Aspirin Genotype 90553(X) 81479 PB855
Biotinidase Deficiency Mutation Analysis 16526(X) 81404 PBF20
Biotinidase Deficiency Mutation Analysis (NY) 16655(X) 81404 PBF20
Biotinidase Activity with Reflex to Mutation Analysis 16537(X)
82261 with reflex to 81404
PBF20 (for 81404)
Bloom Syndrome DNA Mutation Analysis 90872(X) 81209 PBE82
Bloom Syndrome DNA Mutation Analysis (NY) 90873(X) 81209 PBE82
coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payor being billed.
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2014 Molecular CPT Coding with Palmetto PTI codes UPDATED 10/01/2014
The CPT codes provided are based on AMA guidelines and are for informational purposes only. CPT
Quest Diagnostics Test Name
Quest Diagnostics Order Code 2014 CPT Codes Palmetto PTI
BRCAvantage(TM), Ashkenazi Jewish Screen 91864(X) 81212 PBABB
BRCAvantage(TM), Comprehensive 91863(X) 81211, 81213 PBABA
BRCAvantage(TM), Rearrangements 91866(X) 81213, 81479 PBABE
BRCAvantage(TM), Single Site 91865(X) 81215 or 81217 PBZBC or PBABD
BRAF Mutation Analysis 16767(X) 81210 PBC87
Melanoma, BRAF V600E, V600K 92131(X) 81210 ZB064
BRAF Mutation Analysis Papillary Thyroid Cancer 90477(X) 81210 PBC88
BRAF Mutation Analysis, ASO 90868(X) 81210 PBC86
C Kit Mutations w/ Reflex to PDGFRA Mutations 16237(X)
81404 with reflex to 81404
PBC37 with reflex to PBC95
CAH (21-Hydroxylase Deficiency) Common Mutations 14755(X) 81402 PBE83
CAH (21-Hydroxylase Deficiency) Common Mutations (NY) 15063(X) 81402 PBE83
CAH (21-Hydroxylase Deficiency) Common Mutations, Fetal Cells 91680(X) 81402 PBE83
CAH (21-Hydroxylase Deficiency) Rare Mutations 16072(X) 81405 PBF22
CAH (21-Hydroxylase Deficiency) Rare Mutations (NY) 16073(X) 81405 PBF22
Calreticulin (CALR) Mutation Analysis 92074(X) 81479 PBACZ
coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payor being billed.
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2014 Molecular CPT Coding with Palmetto PTI codes UPDATED 10/01/2014
The CPT codes provided are based on AMA guidelines and are for informational purposes only. CPT
Quest Diagnostics Test Name
Quest Diagnostics Order Code 2014 CPT Codes Palmetto PTI
Canavan Disease Mutation Analysis 90905(X) 81200 PBE84
Canavan Disease Mutation Analysis (NY) 90906(X) 81200 PBE84
Cardio IQ(TM) 9p21 Genotype 90648(X) 81479 PB856
Cardio IQ(TM) ApoE Genotype 90649(X) 81401 PBD28
Cardio IQ(TM) KIF6 Genotype 90645(X) 81479 PBD23
Cardio IQ(TM) LPA Aspirin Genotype 90553(X) 81479 PB855
Cardio IQ(TM) LPA Intron-25 Genotype 90655(X) 81479 PBD26
Cardio IQ(TM) 4q25-AF Risk Genotype 90948(X) 81479 PBD25
Cardio IQ(TM) CYP2C19 Genotype 90668(X) 81225 PBD27
CBFB/MYH11 inv(16), Quantitative Real-Time PCR 14992(X) 81401 PBF23
CEBPA Mutation Analysis 90812(X) 81403 PBC59
CEBPA Mutation Analysis, Extracted DNA 90813(X) 81403 PBC60
CFTR Intron 8 Poly-T Analysis 15053(X) 81224 PBR20
CFTR Intron 8 Poly-T Analysis (NY) 14700(X) 81224 PBR20
Chromosomal Microarray, Oncology, ClariSure(R) Oligo-SNP, FFPE 91426(X) 81406 PBZB1
coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payor being billed.
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2014 Molecular CPT Coding with Palmetto PTI codes UPDATED 10/01/2014
The CPT codes provided are based on AMA guidelines and are for informational purposes only. CPT
Quest Diagnostics Test Name
Quest Diagnostics Order Code 2014 CPT Codes Palmetto PTI
Melanoma, Chromosomal Microarray, ClariSure(R) Oligo-SNP 91427(X) 81406 PBZB2
Chromosomal Microarray, Hematologic Malignancy, ClariSure(R) Oligo-SNP 90961(X) 81406 PBF45
Chronic Lymphocytic Leukemia, IgVH Mutation Status, Cell-based 15480(X) 81263 PBC38
Chronic Lymphocytic Leukemia, IgVH Mutation Status, Leumeta® 17702(X) 81263 PBC38
C-KIT Mutation Analysis, Cell-based 19961(X) 81404 PBC37
c-kit Mutation Analysis, Plasma-based, Leumeta(R) 19960(X) 81404 PBC37
CKR-5 Gene, DNA Mutation Analysis 38956(X) 81400 PBF25
Colorectal Cancer Mutation Panel (KRAS, PIK3CA, BRAF, NRAS) 18902(X)
81275, 81210, 81404, 81404
PBF73, ZBC57, PBC87, PBC55,
ColoVantage™ (methylated Septin 9) 16983(X) 81401 PBE85
ColoVantage™ (methylated Septin 9) (NY) 16984(X) 81401 PBE85
Complete Cadasil Evaluation 10978(X) 81406 PB866
Complete HNPP Evaluation 15590(X) 81324, 81325 PBG48
CYP2C19 Genotyping 16605(X) 81225 ZB763
CYP2C19 Genotyping (NY) 16608(X) 81225 ZB763
Cystic Fibrosis Complete Rare Mutation Analysis, Entire Gene Sequence 10917(X) 81223 PBF66
coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payor being billed.
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2014 Molecular CPT Coding with Palmetto PTI codes UPDATED 10/01/2014
The CPT codes provided are based on AMA guidelines and are for informational purposes only. CPT
Quest Diagnostics Test Name
Quest Diagnostics Order Code 2014 CPT Codes Palmetto PTI
Cystic Fibrosis Complete Rare Mutation Analysis, Entire Gene Sequence (NY) 10919(X) 81223 PBF66
Cystic Fibrosis D1152H Mutation Analysis 15335(X) 81221 PBF67
Cystic Fibrosis D1152H Mutation Analysis (NY)
15336(E 4X) 81221 PBF67
Cystic Fibrosis DNA Analysis, Fetus 10226(X) 81220, 88235 PBF68
Cystic Fibrosis DNA Analysis, Fetus (NY) 10478(X) 81220, 88235 PBF68
Cystic Fibrosis Gene Deletion or Duplication 16080(X) 81222 PBE86
Cystic Fibrosis Gene Deletion or Duplication (NY) 16081(X) 81222 PBE86
Cystic Fibrosis Rare Mutation Analysis, One Exon 10913(X) 81221 PBE87
Cystic Fibrosis Rare Mutation Analysis, One Exon (NY) 10914(X) 81221 PBE87
Cystic Fibrosis Rare Mutation Analysis, Two Exon 10915(X) 81221 PBE88
Cystic Fibrosis Rare Mutation Analysis, Two Exon (NY) 10916(X) 81221 PBE88
Cystic Fibrosis Screen 10458(X) 81220 ZB749
Cystic Fibrosis Screen (NY) 10463(X) 81220 ZB749
Cystic Fibrosis Mutation Screen with reflex to CF Complete 17726(X)
81220 with reflex to 81223
ZB749 with reflex to PBF66
Cystic Fibrosis Mutation Screen with reflex to CF Complete (NY) 17727(X)
81220 with reflex to 81223
ZB749 with reflex to PBF66
coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payor being billed.
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2014 Molecular CPT Coding with Palmetto PTI codes UPDATED 10/01/2014
The CPT codes provided are based on AMA guidelines and are for informational purposes only. CPT
Quest Diagnostics Test Name
Quest Diagnostics Order Code 2014 CPT Codes Palmetto PTI
Cytochrome P450 2C9 Genotype 11294(X) 81227 PBF64
Cytochrome P450 2C9 Genotype (NY) 11295(X) 81227 PBF64
Cytochrome P450 2D6 Genotype 10490(X) 81226 PBE89
Cytochrome P450 2D6 Genotype (NY) 14589(X) 81226 PBE89
Cytochrome P450 2D6/2C19 Genotyping 17634(X) 81225, 81226 PBE76, PBE89
Cytochrome P450 2D6/2C19 Genotyping (NY) 17662(X) 81225, 81226 PBE76, PBE89
Cytomegalovirus Genotype 14980(X) 87910 PBD29
Dihydropyrimidine Dehydrogenase (DPD) Gene Mutation Analysis 15538(X) 81400 PBF48
Dihydropyrimidine Dehydrogenase (DPD) Gene Mutation Analysis (NY) 15539(X) 81400 PBF48
Dystonia (DYT1) DNA Test 14678(X) 81400 PBG11
EML4-ALK Gene Fusion, PCR 16344(X) 81401 PBC54
Epidermal Growth Factor Receptor (EGFR) Mutation Analysis 16460(X) 81235 PBC98
Factor V (Leiden) Mutation Analysis 17900(X) 81241 PBF85
Factor V (Leiden) Mutation Analysis (NY) 17901(X) 81241 PBF85
Factor V (Leiden) Mutation Analysis w/Reflex to HR2 Mutation 17904(X)
81241 with reflex to 81400
PBF85 with reflex to PBE90
coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payor being billed.
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2014 Molecular CPT Coding with Palmetto PTI codes UPDATED 10/01/2014
The CPT codes provided are based on AMA guidelines and are for informational purposes only. CPT
Quest Diagnostics Test Name
Quest Diagnostics Order Code 2014 CPT Codes Palmetto PTI
Factor V HR2 Allele DNA Mutation Analysis 17902(X) 81400 PBE90
Factor V HR2 Allele DNA Mutation Analysis (NY) 17903(X) 81400 PBE90
Factor VII R353Q Muation Analysis 16180(X) 81400 PBF26
Factor VII R353Q Muation Analysis (NY) 16181(X) 81400 PBF26
Factor XI Mutation Analysis (Ashkenazi Jewish) 16023(X) 81401 PBF27
Factor XI Mutation Analysis (Ashkenazi Jewish) (NY) 16024(X) 81401 PBF27
Factor XIII V34L Mutation Analysis 16178(X) 81400 PBF28
Factor XIII V34L Mutation Analysis (NY) 16179(X) 81400 PBF28
Familial Adenomatous Polyposis (FAP) Screen 10623(X) 81201, 81203 PBG45
Familial Dysautonomia Mutation Analysis 90912(X) 81260 PBE94
Familial Dysautonomia Mutation Analysis (NY) 90913(X) 81260 PBE94
Familial Mediterranean Fever Mutation Analysis 16141(X) 81402 PBF03
Familial Mediterranean Fever Mutation Analysis (NY) 16142(X) 81402 PBF03
Fanconi Anemia DNA Mutation Analysis (NY) 90898(X) 81242 PBG43
Fanconi Anemia DNA Mutation Analysis 90897(X) 81242 PBG43
coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payor being billed.
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2014 Molecular CPT Coding with Palmetto PTI codes UPDATED 10/01/2014
The CPT codes provided are based on AMA guidelines and are for informational purposes only. CPT
Quest Diagnostics Test Name
Quest Diagnostics Order Code 2014 CPT Codes Palmetto PTI
FLT3 (ITD) and TKD Variant Detection by PCR 90574(X) 81245, 81479 PBC93
Follicular Lymphoma, bcl-2/JH t(14;18), Real-time PCR, Cell-based 15007(X) 81402 PBC39
Follicular Lymphoma, bcl-2/JH t(14;18), Real-time PCR, Leumeta(R) 17690(X) 81402 PBC39
Fragile X DNA Analysis, Fetus 16300(X) 81243 PBF70
Fragile X DNA Analysis, Fetus (NY) 16301(X) 81243 PBF70
FSHD DNA Deletion Test 17029(X) 81404 PBG47
Galactosemia Mutation Analysis 16613(X) 81401 PBF82
Galactosemia Mutation Analysis (NY) 16614(X) 81401 PBF82
Gaucher Disease, DNA Mutation Analysis 90907(X) 81251 PBE92
Gaucher Disease, DNA Mutation Analysis (NY) 90908(X) 81251 PBE92
Genomic Alterations, Oncology, ClariSure(R) CGH 16800(X) 81406 PBF45
Chromosomal Microarray, POC, ClariSure(R) Oligo-SNP 90929(X) 81229 PBABR
Genomic Alterations, Postnatal, ClariSure(R) Oligo-SNP Array 16478(X) 81229 PB635
Chromosomal Microarray, Prenatal, ClariSure(R) Oligo-SNP 90927(X) 81229 PBABR
Glycogen Storage Disease Type Ia Mutation Analysis (Ashkenazi Jewish) 90915(X) 81250 PBK85
coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payor being billed.
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2014 Molecular CPT Coding with Palmetto PTI codes UPDATED 10/01/2014
The CPT codes provided are based on AMA guidelines and are for informational purposes only. CPT
Quest Diagnostics Test Name
Quest Diagnostics Order Code 2014 CPT Codes Palmetto PTI
Glycogen Storage Disease Type Ia Mutation Analysis (Ashkenazi Jewish), NY 90916(X) 81250 PBK85
Hemophilia A (Factor VIII) Inversions 90828(X) 81403 PBZB3
Hepatitis B Virus DNA, Quantitative, Real-Time PCR 8369(X) No 2012 tier code ZB814
Hepatitis B Virus Drug Resistance, Genotype, and BCP/Precore Mutations 10529(X) 87912 PB738
Hereditary Hemochromatosis DNA Mutation Analysis 35079(X) 81256 PBF71
Hereditary Hemochromatosis DNA Mutation Analysis (NY) 36193(X) 81256 PBF71
Hereditary Pancreatitis Mutation Screen 15383(X) 81401 ZBG01
HEXA Mutation Analysis, Gene Sequencing 16612(X) 81406 PBF30
Influenza A H1N1 (2009) Oseltamivir (H274Y) Resistance Detection 16962(X) 87999 ZB672
HLA-B27, DNA Typing 15584(X) 81374 PBG25
HLA-A,B Class I DNA Typing 15757(X) 81373 (x2) PBA77
HLA Class I A,B,C DNA Typing 15484(X) 81372 PBA71
HLA Class II DR, DQ DNA Typing (15485) 15485(X) 81375 PBA74
HLA DQ Class II DNA Typing 10953(X) 81376 PBG27
HLA Typing for Celiac Disease 17135(X) 81382, 81376 PBA73
coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payor being billed.
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2014 Molecular CPT Coding with Palmetto PTI codes UPDATED 10/01/2014
The CPT codes provided are based on AMA guidelines and are for informational purposes only. CPT
Quest Diagnostics Test Name
Quest Diagnostics Order Code 2014 CPT Codes Palmetto PTI
HLA-A Class I DNA Typing 10951(X) 81373 PBA68
HLA-A High Resolution SBT Typing 17397(X) 81380 PBG15
HLA A Low Resolution Qual HLA A2N 92077(X) 81373
HLA HR, ABC DR DQ Qual 92076(X) 81382 (x2), 81379
HLA ABC High Resolution Qual HLAHR, ABC 92078(X) 81379
HLA-A,B, Intermediate Resolution Typing for Transplantation 92158(X) 81373 (x2)
HLA-A,B,C, Intermediate Resolution Typing for Transplantation 92157(X) 81372
HLA-DRB1, DQB1, Intermediate Resolution Typing for Transplantation 92159(X) 81376 (x2)
HLA-DRB1, Intermediate Resolution Typing for Transplantation 92160(X) 81376
HLA-DRB3, 4, 5, Intermediate Resolution Typing for Transplantation 92161(X) 81376
HLA-A,B Class I DNA Typing (15757) 15757(X) 81373 (x2) PBA77
HLA-A,B,C CLASS I DNA TYPING 15484(X) 81372 PBA71
HLA-A2 High Resolution SBT Subtyping 17492(X) 81381 PBK78
HLA-A2 Subtyping 92044(X) 81380 PBA68
HLA-A29 DNA Typing 16773(X) 81374 PBG17
coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payor being billed.
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2014 Molecular CPT Coding with Palmetto PTI codes UPDATED 10/01/2014
The CPT codes provided are based on AMA guidelines and are for informational purposes only. CPT
Quest Diagnostics Test Name
Quest Diagnostics Order Code 2014 CPT Codes Palmetto PTI
HLA-B Class I DNA Typing 10950(X) 81373 PBA69
HLA-B High Resolution SBT Typing 17396(X) 81380 PBG18
HLA-B*1502 Typing 40045(X) 81381 PBG23
HLA-B*5701 Typing 19774(X) 81381 PBG24
HLA-B27, DNA Typing 15584(X) 81374 PBG25
HLA-B51 DNA Typing 16775(X) 81374 PBG26
HLA-C Class I DNA Typing 15463(X) 81373 PBA70
HLA-C High Resolution SBT Typing 17395(X) 81380 PBG19
HLA-DRB1 Class II DNA Typing 10952(X) 81376 PBA72
HLA-DQA1 DNA Typing 19525(X) 81376 PBG28
HLA-DQB1 Class II DNA Typing 10953(X) 81376 PBG27
HLA-DQB1 High Resolution SBT Typing 17394(X) 81382 PBG20
HLA Class II DR, DQ DNA Typing 15485(X) 81375 PBA74
HLA-DRB 3*4*5 DNA Typing 19526(X) 81376 PBA75
HLA-DRB1 High Resolution SBT Typing 17393(X) 81382 PBG21
Human Platelet Antigen 1 Genotype 10707(X) 81400 PBE93
Huntington Disease Mutation Analysis 10247(X) 81401 PBE95
Huntington Disease Mutation Analysis (NY) 14871(X) 81401 PBE95 JAK2 Exons 12 and 13 Mutations, Qualitative, Leumeta(R) 16536(X) 81403 PBC40 JAK2 Mutation (V617F) Analysis, Quantitative, Plasma-based, Leumeta(R) 16175(X) 81270 PB646 JAK2 V617F, Qualitative, Leumeta® with Reflex to Exons 12,13 16539(X)
81270 reflex to 81403
PBF78 with reflex to PBC40
coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payor being billed.
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2014 Molecular CPT Coding with Palmetto PTI codes UPDATED 10/01/2014
The CPT codes provided are based on AMA guidelines and are for informational purposes only. CPT
Quest Diagnostics Test Name
Quest Diagnostics Order Code 2014 CPT Codes Palmetto PTI
JAK2 V617F, Qualitative, Leumeta® with Reflex to Exons 12,13 and Reflex to MPL W515, S505 16538(X)
81270 reflex to 81403 (JAK 12,13) and/or reflex 81402
PBF78 with reflex to PBC40 and/or reflex PBC42
JAK2 Mutation (V617F), Quantitative 18950(X) 81270 PBF77
Stratify JCV ™ Antibody w/reflex to Inhibition Assay 90257(X)
86711 w/reflex to 86711
KIT D816, Mutation analysis (Mastocytosis) 91772(X) 81402 PBABQ
KRAS Mutation Analysis 16510(X) 81275 PBF73 Long Chain Acyl-CoA Dehydrogenase (LCHAD) Mutation Analysis (NY) 11247(X) 81479 PBF31 Long Chain Acyl-CoA Dehydrogenase (LCHAD) Mutation Analysis 11244(X) 81479 PBF31
Lung Cancer Mutation Panel (EGFR, KRAS, ALK) 91216(X)
81235, 81275, 88271 (x2), 88274 PBC98, PBF73
Lymphocyte Clonality Panel, PCR 91634(X)
81261, 81264, 81342, 81340, 84999 (HCPCS: G0452)
PBZB7, PBZB8, PBZB9, PBZC1
Lynch Syndrome, MLH1 Sequencing and Deletion/Duplication 91460(X) 81292, 81294 PBZA3
Lynch Syndrome, MLH1 Familial Deletion/Duplication 91584(X) 81294 PBZA9 Lynch Syndrome, MSH2 Sequencing and Deletion/Duplication (Including EPCAM) 91471(X)
81295, 81297, 81403 PBZA4
Lynch Syndrome, MSH6 Sequencing and Deletion/Duplication 91458(X) 81298, 81300 PBZA5 Lynch Syndrome, PMS2 Sequencing and Deletion/Duplication 91457(X) 81317, 81319 PBZA6
Lynch Syndrome, PMS2 Familial Deletion/Duplication 91463(X) 81319 PBZA7 Lynch Syndrome, MSH2 Familial Deletion/Duplication (Including EPCAM) 91459(X) 81297, 81403 PBZA8
coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payor being billed.
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2014 Molecular CPT Coding with Palmetto PTI codes UPDATED 10/01/2014
The CPT codes provided are based on AMA guidelines and are for informational purposes only. CPT
Quest Diagnostics Test Name
Quest Diagnostics Order Code 2014 CPT Codes Palmetto PTI
Lynch Syndrome Panel 91461(X)
81292, 81295, 81298, 81317, 81294, 81300, 81319, 81403, 81297 PBZA2
Macular Degeneration Mutation Analysis 16155(X) 81401 PBF32
Macular Degeneration Mutation Analysis(NY) 16156(X) 81401 PBF32 Mantle Cell Lymphoma, bcl-1/JH t(11;14), Real-time PCR, Cell-based 14991(X) 81401 PBC41 Mantle Cell Lymphoma, bcl-1/JH t(11;14), Real-time PCR, Leumeta(R) 17679(X) 81401 PBC41 Maple Syrup Disease (MSUD) Mutation Analysis (Ashkenazi Jewish) 90909(X) 81205 PBE96 Maple Syrup Disease (MSUD) Mutation Analysis (Ashkenazi Jewish) (NY) 90911(X) 81205 PBE96
Maternal Cell Contamination Study, STR Analysis 10262(X) 81265 PBE97
Maternal Cell Contamination Study, STR Analysis (NY) 10477(X) 81265 PBE97 Medium Chain Acyl-CoA Dehydrogenase (MCAD) Mutation Analysis 11176(X) 81400 PBF34 Medium Chain Acyl-CoA Dehydrogenase (MCAD) Mutation Analysis (NY) 10921(X) 81400 PBF34 Medium Chain Acyl-CoA Dehydrogenase (MCAD) Gene Sequencing 91284(X) 81401 PBZB4
Melanoma, BRAF V600 Mutation, Cobas 90956(X) 81210 ZB794
MEN2 and FMTC Mutations, Exons 10, 11, 13-16 36587(X) 81404, 81405 PBF98
MEN2 and FMTC Mutations, Exons 10, 11, 13-16 (NY) 36091(X) 81404, 81405 PBF98 Methylenetetrahydrofolate Reductase (MTHFR), DNA Mutation Analysis 17911(X) 81291 PBF93 Methylenetetrahydrofolate Reductase, DNA Mutation Analysis (NY) 17912(X) 81291 PBF93
Microsatellite Instability (MSI), HNPCC 14989(X) 81301 PBC94
coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payor being billed.
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2014 Molecular CPT Coding with Palmetto PTI codes UPDATED 10/01/2014
The CPT codes provided are based on AMA guidelines and are for informational purposes only. CPT
Quest Diagnostics Test Name
Quest Diagnostics Order Code 2014 CPT Codes Palmetto PTI
Mitochondrial DNA Disorders, Panel I 10631(X) 81479 PB737
Mitochondrial DNA Disorders, Panel II 10632(X) 81479 PBG34
MLH1 Mutation, One Exon, HNPCC 14984(X) 81293 PBF53
MLH1 Mutation, One Exon, HNPCC (NY) 15012(X) 81293 PBF53 MPL W515 and MPL S505 Mutation Analysis, Qualitative, Leumeta(R) 16184(X) 81402 PBC42
MSH2 Gene Sequencing, HNPCC 16929(X) 81295 PBF54
MSH2 Mutation, One Exon, HNPCC 14981(X) 81296 PBF55
MSH2 Mutation, One Exon, HNPCC (NY) 15013(X) 81296 PBF55
MSH6 Mutation, HNPCC (NY) 15015(X) 81298 PBF56
MSH6 Gene Deletion or Duplication 91230(X) 81300 PBZ52
MSH6 Mutation, One Exon, HNPCC 14983(X) 81299 PBF57
MSH6 Mutation, One Exon, HNPCC (NY) 15014(X) 81299 PBF57
Mucolipidosis Type IV Mutation Analysis 90899(X) 81290 PBF35
Mucolipidosis Type IV Mutation Analysis (NY) 90901(X) 81290 PBF35
MYD88, Mutation Analysis 91771(X) 81479 PBABP
Myelodysplastic Syndrome (MDS) Mutations, Sequencing 91396(X)
81404, 81275, 81403 (x2), 81479 PBAAC
Myelodysproliferative Neoplasm Mutation (w/o BCR/ABL, JAK2, MPL) 91401(X)
81404, 81275, 81403 (x2), 81479 PBAAC
Myotonic Dystrophy DNA Test 36164(X) 81401 PBG39
Niemann-Pick Disease Mutation Analysis 90893(X) 81330 PBF36
Niemann-Pick Disease Mutation Analysis (NY) 90895(X) 81330 PBF36
NPM (Exon 12) Mutation Analysis, Cell-based 16158(X) 81310 PBC43
coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payor being billed.
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2014 Molecular CPT Coding with Palmetto PTI codes UPDATED 10/01/2014
The CPT codes provided are based on AMA guidelines and are for informational purposes only. CPT
Quest Diagnostics Test Name
Quest Diagnostics Order Code 2014 CPT Codes Palmetto PTI
NPM (Exon 12) Mutation Analysis, Plasma-based, Leumeta(R) 16159(X) 81310 PBC43
NRAS Mutation Analysis 16818(X) 81404 PBC55
OncoVantage™ 91919(X)
81210, 81235, 81275, 81321, 81403 (x5), 81404 (x6), 81405 (x2), 81479 PBBBM
P53 Mutation Analysis, Plasma-based, Leumeta(R) 16515(X) 81405 PBC44
Pain Management, CYP450 3A4 Genotype, Qual 91617(X) 81401 PBZB5
Pain Management, CYP450 3A5 Genotype, Qual 91618(X) 81479 PBZB6
Pain Management, CYP450 2D6/2C19 Genotype, Qual 18946(X) 81226, 81225 PBE76, PBE89
PAX8/PPAR translocation 90474(X) 81401 PBC56
PDGFRA Mutation Analysis 16859(X) 81404 PBC95
Phenylketonuria (PKU) Mutation Analysis 16152(X) 81406 PBF37
Phenylketonuria (PKU) Mutation Analysis (NY) 16153(X) 81406 PBF37
PIK3CA Mutation Analysis 16897(X) 81404 ZBC57
Plasminogen Activator Inhibitor-1 (PAI-1) 4G/5G 11368(X) 81400 PB643
Plasminogen Activator Inhibitor-1 (PAI-1) 4G/5G (NY) 14518(X) 81400 PB643 PML/RARA t(15;17), Quantitative Real-Time PCR, Cell-based 14994(X) 81315 ZBC58 PML/RARA t(15;17), Quantitative Real-Time PCR, Plasma-based, Leumeta(R) 70182(X) 81315 ZBC58
PMP22 Duplication/Deletion DNA Test 824(X) 81324 PBG49 Prader-Willi/Angelman Syndrome, DNA Methylation Analysis 11369(X) 81331 PB740 Prader-Willi/Angelman Syndrome, DNA Methylation Analysis (NY) 14470(X) 81331 PB740
coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payor being billed.
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2014 Molecular CPT Coding with Palmetto PTI codes UPDATED 10/01/2014
The CPT codes provided are based on AMA guidelines and are for informational purposes only. CPT
Quest Diagnostics Test Name
Quest Diagnostics Order Code 2014 CPT Codes Palmetto PTI
Prenatal Carrier Screen (CF, Fragile X, SMA) 90949(X)
81220, 81243, 81401 with possible southern blot
ZB749, PB320, PBBZ0
Prostate Cancer Antigen 3 (PCA3) 91054(X) 81479 ZBA41
Progensa(R) PCA3 92028(X) 81479 ZBA41
Prothrombin (Factor II) 20210G>A Mutation Analysis 17909(X) 81240 PBF84 Prothrombin (Factor II) 20210G>A, Mutation Analysis (NY) 17910(X) 81240 PBF84
RAS Mutation Analysis, Cell-based 16128(X)
81403, 81404, 81275 PBD78
RAS Mutation Analysis, Plasma-based Leumeta(R) 16127(X)
81403, 81404, 81275 PBD78
RAS Mutation Analysis, Thyroid Cancer 90479(X)
81403, 81404, 81275 PBD79
Renal Transplant Monitoring (FOXP3, Granzyme B, Perforin, IP10) 90986(X) 81479 PBZ51 Renal Transplant Monitoring (FOXP3, Granzyme B, Perforin, IP10) (NY) 90987(X) 81479 PBZ51
Resistance to Thyroid Hormone (RTH) Mutation Analysis 16053(X) 81405 PBF38
Resistance to Thyroid Hormone (RTH) Mutation Analysis (NY) 16054(X) 81405 PBF38
RET/PTC Rearrangement, Thyroid Cancer 90473(X) 81479 PBC97
Rett Syndrome Mutation Analysis 15088(X) 81302 PBF99
Rett Syndrome Mutation Analysis (NY) 15089(X) 81302 PBF99
Rett Syndrome Rearrangement (Deletion or Duplication) 16662(X) 81304 PB642
Sarcoma Mutation Analysis Panel, Pediatric, PCR 19884(X)
81401 (x5), 81479 PBD75
SHOX (GHD) DNA Sequencing and Deletion 91566(X) 81405, 81479 PBO50
Sickle Cell Anemia, DNA Probe Analysis, Fetus 26382(X) 88235, 81401 PBF74
Sickle Cell Anemia, DNA Probe Analysis, Fetus (NY) 36194(X) 88235, 81401 PBF74
coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payor being billed.
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2014 Molecular CPT Coding with Palmetto PTI codes UPDATED 10/01/2014
The CPT codes provided are based on AMA guidelines and are for informational purposes only. CPT
Quest Diagnostics Test Name
Quest Diagnostics Order Code 2014 CPT Codes Palmetto PTI
SMA Carrier Screen 18041(X) 81401 PBBZ0
SMA Diagnostic Test 16869(X) 81401 PBBZ0
Small Fiber Painful Axonal Profile 10539(X)
83516, 83520 (x2), 81404 PBJ20
Tamoxifen P450 Genotype 16731(X) 81226 PBE06
Tamoxifen P450 Genotype (NY) 16732(X) 81226 PBE06
Tay Sachs Disease Mutation Analysis (NY) 90904(X) 81255 PBF62
Tay-Sachs Disease Mutation Analysis 90903(X) 81255 PBF62
T-cell Receptor (TCR) Beta Gene Rearrangement, PCR 91446(X)
81340, 84999 (HCPCS: G0452) PBZB8
T-cell Receptor (TCR) Gamma Gene Rearrangement, PCR 90509(X)
81342, 84999 (HCPCS: G0452) PBZB7
T-cell Clonality Panel (TCRB, TCRG), PCR 91445(X)
81342, 81340, 84999 (HCPCS: G0452) PBZB7, PBZB8
Thrombophilia DNA Mutation Analysis 17907(X) 81240, 81241 PBF91
Thrombophilia DNA Mutation Analysis (NY) 17908(X) 81240, 81241 PBF91 Thrombophilia Mutation Analysis with Reflex to HR2 Mutation 11126(X)
81240, 81241 with reflex to 81400
PBF85, PBF84 with reflex to PBE90
Thyroid Cancer Mutation Panel – BRAF, RAS, RET/PTC, PAX8/PPAR 90469(X)
81210, 81403, 81275, 81404 (x2), 81401
PBC88, PBD79, PBC97, PBC56
TPMT Genotype 37742(X) 81401 PBF58
TPMT Genotype (NY) 16108(X) 81401 PBF58
Trofile Co-receptor Tropism Assay 19995(X) 87906 PBC62
Twin Zygosity (NY) 10557(X) 81265 PBF39
Twin Zygosity 10556(X) 81265 PBF39
UGT1A1 Gene Polymorphism (TA Repeat) 17813(X) 81350 PBF61
UGT1A1 Gene Polymorphism (TA Repeat) (NY) 16111(X) 81350 PBF61
coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payor being billed.
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2014 Molecular CPT Coding with Palmetto PTI codes UPDATED 10/01/2014
The CPT codes provided are based on AMA guidelines and are for informational purposes only. CPT
Quest Diagnostics Test Name
Quest Diagnostics Order Code 2014 CPT Codes Palmetto PTI
UGTIA1 Genotyping (NY) 16522(X) 81350 ZBB13
UGTIA1 Genotyping 16521(X) 81350 ZBB13
VEGF Polymorphism Analysis 16959(X) 81479 PBQ78
von Willebrand Disease Mutation Analysis 19837(X) 81406 PBF94
von Willebrand Disease Mutation Analysis (NY) 19838(X) 81406 PBF94
Wilms' Tumor 1 (WT1) Mutation Analysis 16896(X) 81405 PBF40
Wilson Disease Mutation Screen, ATP7B DNA Sequence 59142(X) 81406 PBG46
XSense(R), Fragile X with Reflex 16313(X)
81243 with reflex to 81244
PB320 with reflex to PBZA1
XSense(R), Fragile X with Reflex (NY) 16321(X)
81243 with reflex to 81244
PB320 with reflex to PBZA1
Y Chromosome Microdeletion, DNA Analysis 14679(X) 81403
Y Chromosome Microdeletion, DNA Analysis (NY) 16018(X) 81403
coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payor being billed.
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2014 Molecular CPT Coding with Palmetto PTI codes UPDATED 10/01/2014
The CPT codes provided are based on AMA guidelines and are for informational purposes only. CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payor being billed.
23
Quest Diagnostics Test Name
Quest Diagnostics Order Code 2014 CPT Codes Palmetto PTI
Benzene Incident Urine (OSHA) 16883(X) 81099, 84600 PBQ33
Interferon-beta 1a (IFNB-1a) Ab 16201(X) 86382, 87253 PBK65
Interferon-beta 1b (IFNB-1b) Ab 16202(X) 86382, 87253 PB937
Interferon-beta IgG, MAID 19509(X) 83520 PB939
Limulus Amebocyte Lysate Assay 14453(X) 87999 PB966
Osmolality, Feces 968(X) 84999 PBK99
OVA1(TM) 16991(X) 84999 PB627
OVA1(TM) (includes FSH and LH) 16992(X)
84999, 83001, 83002 PBL00