2009 Technology Transfer Annual Report

T E C H N O L O G Y T R A N S F E R

ADVANCING INNOVATION AND ENTREPRENEURSHIP

U T I N N O VAT I O N E N T E R P R I S E S

A N N U A L R E P O RT O N T E C H N O L O G Y T R A N S F E RFiscal Year 2009

Martin Abraham• Anovelsulfur-tolerantcatalystforsteamreformingofdiesel

andjetfuel

Malabala Adiga• Methodofplatingelectrocatalystforhydrogengeneration

Jared Anderson, Fei Zhao, Yunjing Meng, Zhao Qi Chao• Polymericionicliquidsasabsorbentcoatingsinsolidphase

microextraction

Ragheb Assaly, Joseph Shapiro, John Dignam• UseofPEG-Albuminasaplatformfordeliveryofantioxidant

andothermedications

Abdul-Majeed Azad• Carbondioxideandwater-basedfuelcells• HighTemperatureSulfurSorbents(ZSeries)• Carbondioxideandwater-basedfuelcells

Abdul-Majeed Azad, Desikan Sundararajan• Exhaustgaspurificationcatalysts• Acetylenegassensor

Michael Bisesi, Christopher Bork, Paul Rega • Cot-AID(AssistiveIntegratedDevices)(11separatedevicesdisclosed)

Ashok Biyani• Modifiedpediclescrewtipforone-steppercutaneousinsertion• Unidirectionalrotarypediclescrewforcorrectionofspinaldeformity

ingrowingchildren• Directionalsofttissuedilatorsanddockingpinwithintegratedlight

sourceforoptimizationofretractorplacementinminimallyinvasivespinesurgery

• Derotationpediclescrewdesignforsurgicalcorrectionofspinaldeformity

• Fixedandpreloadcompressioncervicalplateswithandwithoutintegratedlockingmechanism

• Posteriorfixationdeviceforpercutaneousstabilizationofthoracolumbarburstfractures

• Expandablecorpectomycageconcept

Ashok Biyani, Philip Nowicki• Femoralneckwasherfixationsystem

Ashok Biyani, Brian Blessinger• Anintegrateddeviceforstorageanddeliveryofbonegraftor

implantablematerial

Ashok Biyani, Gary Durivage• AdjustableHeightPedicleScrew

Christopher Bork• Anergonomichandleforrollingluggage

Thomas Cable, John Setlock• Reformerdesignusingsymmetrical,oxygenconductivemembranes

Brent Cameron, Scott Pappada• Aneuralnetworkbasedapproachforphysiologicalglycemic

forecasting

George Cicila, Soon Jin Lee, Justin Ways• Congenicratstrains(6separatestrainsdisclosed)

Maria Coleman, Hamidreza Hakimelahi, Javed Mapkar• Functionalnanocompositenetworkforreverseselectivemembranes

Alvin Compaan• RapidthermalactivationofflexibleCdTecellsandmodules• Methodtoimproveadhesionofthin-filmsolarcellcoatingsto

polymerfilm• MethodtomakeflexibleCdTemodulesonpolymercastonstainless

steelwebforroll-to-rollmanufacturing

Christopher Cooper• Vascularqualityassurance

Xunming Deng, Qi Hua Fan, Shiban Zhang• PulsedDCreactivesputteringdepositionofzincoxidethinfilmsfrom

zincmetaltarget

Michael Dennis, Dean Walton• ScatterreductioninEPIDradiography

John Dismukes, Lawrence Miller, John Bers• ARImethodologyandscorecardtoolforacceleratingbreakthrough

innovations

Mohammad Elahinia, James Maloney, Majid Tabesh, Richard Yeasting• Bio-inspiredshapememoryalloyesophaguspositioner

Mohammad Elahinia, Vijay Goel, Majid Tabesh• Bio-inspiredshapememoryalloypediclescrewtocompensateforbone

degradationinosteoporosispatients

Mohammad Elahinia, The Nguyen• Mixed-modesemiactivemagnetorheologicalmount

Qi Hua Fan, Xianbo Liao, Xunming Deng, Xianbi Xiang• Highefficiencythinfilmsolarcellsmadewithgradedlightabsorber

materials

Vijay Goel, Hossein Elgafy, Ahmad Faizan• Cervicalspineposteriordynamicsysteminconjunctionwithanartificial

disctotreatthewhiplashinjurypatients

Vijay Goel, Aaron Matyas• Anchoringpediclescrew• Minimallyinvasivecollapsiblecage

Miles Hacker• Usinginactiveanti-cancerdrugstotreatcysticfibrosis

Marthe Howard• Innovativenewtreatmentstrategyforglioma

Dragan Isailovic• Florophore-assistedlaserdesorptionionizationmassspectrometry

(FALDI-MS)

Samer Khouri, Sonia Najjar• Novelmodelofthemetabolicsyndromewithassociatedspontaneous

atherosclerosis

Dong-Shik Kim, Maria Coleman• SuspensiontechniqueforGochangyellowclay

Tony Koesters, Brian Kanney, Ryan Kremer, Allan Gindy, Faisal Bukhari• BurnableShreddedPaperLogs

Yun-Ming Lin• Reactionrateaccelerationviaasymmetricbifunctionalcatalysis

Terri Lombardo• Novelrenewableelectricenergy

Ioan Marinescu• Penetratingcompoundswithvariableproperties

Mark Mason• Newtrianionicligandsforconstrainedgeometrycatalysts

Udayan Nadkeolyar• Pilotfreehighspeedsurfacetransportationcapsule

Philip Nowicki, Ashok Biyani, Martin Skie• Antibioticclusteredpercutaneouspincoversystem

Thomas Papadimos• Thebeneficialeffectsofinhalednitricoxideinpatientswithsevere

traumaticbraininjurycomplicatedbyacuterespiratorydistresssyndrome

Invention DisclosuresCatherine Powell• MARKtheSpot–Answersonthespot• Backlace

Carmen Quatman, Andrew Maszaros, Catherine Quatman• Shoulderbracefordecreasedpassiverestraints

Martin Rice• Learningtotelltimeusingknowledgeofresults

Edwin Sanchez, Garrett Heinrich, Terry Hinds• Discoveryofglucocorticoidreceptorbetainmice

Rebecca Schneider• ALearningCommunityofTeachers(ALCOT)

Steven Selman, Hinman Channing• Applicationsofcobratoxinandderivatives

Lirim Shemshedini, Changmeng Cai, Shao-Yong Chen, Chen-Lin Hsieh• Solubleguanylylcyclasealpha1(sGCalpha1)asanoveldiagnostic

markerofandthereapeutictargetforprostatecancer• V94Cells:Anovelandrogen-independentLNCaPcellline

Krishna Shenai, Nikhil Gudi, Dhakshina Thavamani• Anovelhybridthermoelectricenergyconverter(TEC)andphotovoltaic

(PV)system

Krishna Shenai, Nikhil Gudi, Dhakshina Thavamani, Premchand Boyapati, Prashanth Reddy• HybridsmartmodularDCpowersystem

Krishna Shenai, Nikhil Gudi• Wirelesssmartmovableantenna• Remotelycontrollablesmartwidebandwirelessantenna• Smartwirelesslytunablecommunicationsystempowerfrom

renewableenergysources

Krishna Shenai, Ashok Biyani, Vijay Goel, Vijay Devabhaktuni, Bradford Lilly• Anovelprocedureandapparatusforperforminghighly

accuratesurgery

Krishna Shenai, Premchand Boyapati, Dhakshina Thavamani, Jessica Jordan• Novelwirelesssensorcommunicationusingsoundwaves

Krishna Shenai, Premchand Boyapati• Multi-functionlow-powerwirelessairsensor• Smartremotesensingandwirelessinformationmanagement• Anovelwirelesssensorsystemforstructuralhealthmonitoring

Krishna Shenai, Bradford Lilly, Premchand Boyapati• Automatedswimmingpoolmanagementsystem• Amethodforpreciseintelligentsoilchemicaldistribution

Thomas Stuart• Amodularizedsystemwithrelaysformanagingseriesconnected

batterycells

Zi-Jian Xie Jiang Tian• Na/K-ATPaseexpressionasanindicatorfortreatmentofcancer

Zi-Jian Xie, Joseph Shapiro, Zhichuan Li• Na/K-ATPase-derivedpeptidesasantagonistofCTSandas

therapeuticagentsforcancer

Daniel Kory, Ph.D., MBAAssociate Vice President for Technology TransferPhone: 419.383.6924Email: [email protected]

Stephen Snider, J.D.Director, Technology Licensing & Contracts Phone: 419.383.6963

Email: [email protected]

Mark Fox, J.D., MSPatent Technology AssociatePhone: 419.383.6907Email: [email protected]

Samuel Giles, MBAPatent Licensing AssociatePhone: 419.383.6965Email: [email protected]

Sandra RhoadesIP AdministratorPhone: 419.383.6923Email: [email protected]

Contacts

INNOVATIONENTERPRISES

INNOVATIONENTERPRISES

W W W. U T O L E D O . E D U / R E S E A R C H / T E C H T R A N S F E R

IR 1

92 1

009

250

In2009,UTInnovationEnterpriseswascreatedtodiversifyandtransformtheregionaleconomybyfacilitatingthedevelopmentandattractionofscienceandtechnology-basedorganizations.Bybringingtogetherresearchdevelopment,technologytransfer,incubation,workforcedevelopmentandtheScienceandTechnologyCorridor,theUniversitybelievesitwillbeabletoenhancetheglobalcompetitivenessofNWOhio.

The University of Toledo has made a significant commitment to improve the human condition by taking a leadership role in regional economic development. To enable and strengthen these efforts, the University has taken major steps to build up the technology transfer program by adding new staff members to (i) assist in identifying and licensing new technologies and (ii) help develop new spin-off businesses. Lloyd Jacobs, M.D., President of the University, has clearly articulated that the technology transfer group is a core University unit performing highly valued functions with an established ability to identify and license new technologies and create spin-off businesses that result in jobs, economic development and wealth creation. In 2008, Innovation Associates reported in a project funded by the National Science Foundation, based on data from the Association of University Technology Managers (AUTM) that, among US universities, UT ranked 6th in executing licenses and 7th in launching start-up businesses, when taking the level of research expenditures into account — an indication of a very high level productivity in the translation of research into economic development. The US average for invention disclosures per $10 MM of research expenditures is 4.3. UT is significantly higher, increasing from 5.8 to 16 in the past seven years. The number of new license agreements per $10 MM of research expenditures has also increased steadily from 2003 to 2009, from 1.2 to 3.8, versus a national average of 0.4. According to AUTM, the average US University spins-off one business for every $100 MM in research expenditures. At two per year, UT is four times the national average and at three per year, the results in 2007 to 2009, UT is six times the national average. UT now has 16 active spin-off businesses, generating about 100 local technology positions. Several have attracted $1 million + in third party validation funding. Three spin-offs have received funding from Regional Growth Partnership’s Rocket Ventures and four have qualified for the Regional Growth Partnership’s Ignite Program. We look forward to continuing to work closely with the faculty on innovative and entrepreneurial ideas. We believe that the faculty’s continued participation will help us increase UT’s state-wide and national profile as an innovation system that produces new discoveries, new products and/or services, new firms, jobs, and wealth creation.

RichardAndaloroDonaldAngelbeckBernardArulanandamRaghebAssalyBradleyAustermillerKennethBachmannJamesBarilGloriaBorgstahlMichaelBrattainReneeBuchananJeffreyBurnhamJamesByersBrentCameronYangCaoKemingChenXiaChenGarryColeAlvinCompaanErinCrawfordJulianDaviesRobertDeckLaurentDelouxJefferyDeMuthXunmingDengJohnDignamPhilipDunbarGrahamDurantSylvainDutremezPaulErhardtErvinFaulmannRonaldFournierPeterFraleighJamesFryKuan-ChenFuJamesGanoGretaGarboDeanGiolandoVijayGoelPeterGoldblattStephenGoldmanBingGongAnneGravesAkhleshGupta

JiwanGuptaGeorgeHageageJamesHamptonGregoryHaselhuhnJudyHendricksJamesHornerWayneHossRichardHudsonChiung-YuHungJamesHuttnerClaraJacksonDouglasJambard-SweetJerzyJankunRalphJansenVictorKarpovStamatiosKartalopoulosPeterKascakRickKeckAminKhanRogerKingJonKirchhoffThoeKirklandIIIRitaKleinWieslawKlisCharlesKnightStevenKramerKennethKroppFrederickKurtzHaroldLeeAkliluLemmaMarcLevineJeffreyLovelaceEdwardLumsdaineXiandaMaKonstantinMakhratchevMauriceManningWilliamMesserJr.DennisMetzgerAlanMorganNaserMostaghelDurgeshNadkarniGanapathyNaganathanTerryNg

BabatundeOjoHenryPovolnyKentPriceDemetriosRaftopoulosWalajapetRajeswaranGlennReimerWilliamRollYannRoussillonSairamRudrabhatlaJeffreySabinMurraySaffranJeffreySarverPadmanabhanSekherStevenSelmanKalpathiSeshanJosephShapiroDianaShvydkaHenrySimonDimitrisSkalkosJamesSlamaCliffordSmithEdwardSnellMorrisSrebnikSujathaSrinivasanThomasStuartVernerSwansonSridharThirupathiLiyanaaratchingeTillekeratneJamesTrempeStefanUhlenbrockSasidharVaranasiYuWangDavidWeaverJamesWilleyJianminXueQichengYangZhongYeJieh-JuenYuQuilinYuBinZhengDonaldZrudsky

Gene ExpressJim WilleyJune 1998 Agenomicsbiotechcompanyprovidinggeneassaystoassistpharmaceuticalandbiotechcompanieswithdrugdevelopmentandexpressionanalysis.

Schneider & Morse Group Roy Schneider and Dennis Morse April 2001 Astart-upfocusedondevelopingcomputer-basededucationaltoolsforanimalanatomyanddissection

Mithridion Wayne Hoss and Bill Messer January 2002 Anemergingbiotechcompanyfocusedonthediscoveryandcommercializationoftreatmentsforneurologicalandpsychiatricdiseases

Innovative Thin Films, Ltd. Dean Giolando March 2004 Acompanyfocusedonprovidingthinfilmsolutionstoproblemsassociatedwiththephotovoltaicindustrysuchasscratching,soilingandreflection

Hi-Genomics Stephen Goldman and Sairam Rudrabhatla April 2004 Avirtualcompanywithtechnologiesintissuecultureandgenetictransformationthatcouplehighoutput,rapid,genotypeindependentregenerationtohighfrequencyDNAtransferusingeitheragrobacteriumorbiolistictransformation

The Turning Point Vijay Goel, Danny Pincivero, John Jaegly, and David Dick June 2005 Amanufacturingandmarketingfirmthatproducesastate-of-the-artgolfexerciseandtherapeuticdevice

Xunlight Xunming Deng January 2006 Amanufacturingandmarketingcompanythatdevelopsthin-filmsiliconbasedphotovoltaicproductsandmanufacturingequipmentforhigh-throughputproductionofflexibleandlightweightphotovoltaicmodulesatlowcost

Spinal DesignsAshok Biyani May 2006 Amarketingfirmthatprovidesproductsandservicestoorthopedicsurgeons.

Freedom Meditech Brent Cameron December 2006 Adevelopmentalstagemedicaldevicecompanyfocusedonthenon-invasivebloodglucosetestingfordiabetics

Suganit Systems Sasidhar Varanasi, Connie Schall, Jared Anderson, and Patricia Relue March 2007 Astart-upcompanyinvolvedintheresearchanddevelopmentofrenewableandcleanenergywithafocusinethanolproductionfrombiomass

ADS Biotechnology, Joseph Shapiro, David Dignam, and Ragheb Assaly January 2008 Revolutionaryapproachforthetreatmentofthreateningclinicalconditions.Thecompany’sprimaryproduct,pegylatedalbumin,isatherapeuticcolloid-typebloodvolumeexpanderagentthatissuperiortohumanserumalbumin

Esclapeus Biopharaceuticals KV Chin May 2008Start-upfocusedondevelopingasmallmoleculeinterventionforobesity,oneofthemostseriouspublichealthrisksintheUSandworldwide

Innovative Water Technologies Dean Giolando May 2008Developingaflashevaporationspraytechnologyforthepurificationand/ordesalinationofwater

Xunlight Solar-26 Al Compaan December 2008DevelopingCdTethin-filmphotovoltaicsonpolyimidesubstrates

Total Compliance Abdul-Majeed Azad February 2009 Start-upplanningtocommercializetechnologyfortheremovalofcarbonmonoxide,organiccompoundsandunburnedhydrocarbonsfromthestreamofcombustiondevicesand/orspraybooths.

JWH Group Abdul-Majeed Azad April 2009Start-upcompanythatisdevelopinggassensortechnology

The University would like to recognize the following University inventors’ contributions in promoting the progress of science through designation as an inventor on one or more patent grants. Names in red are new additions to the list for fiscal year 2009. ADSBiotechnology,Ltd,aUTspin-offcompany,isworking

tocommercializeanewmedicaltreatment,polyethylene-glycol (PEG)-modified albumin, which works to expandblood’svolumesoitwillnotescapeasmayoccurinvariousmedical scenarios where a patient’s blood vessels leak.The company worked with RocketVentures to organizeand secure funding, including a recent investment of$250,000.ADShas submitted applications for grants totheU.S.DepartmentofDefense,theNationalInstitutesofHealth,andtheClevelandClinic.

SuGanitSystems,Inc.,astart-upcompanyresearchingand developing renewable clean energy, acquiredexclusivelicensetotwoUniversityofToledotechnologiesfor producing ethanol from cellulosic biomass. Thecompany has been awarded over $2.1M in fundingfrom the US Department of Energy, USDA, and Ohio’sThird Frontier Advanced Energy Program to developthese technologies. SuGanit is scaling up the licensedtechnologyandisplanningtobuildapilotscalecellulosicethanolfacilityinToledo,Ohio.

Mithridion, Inc. merged with the UT spin-off CognitivePharmaceuticals to develop drugs for neurologicalandpsychiatricdiseases.Thecompanyhasraised$7.4milliontodateinequityfundingandrecentlyannouncedthe results of its Phase I pharmacokinetic and clinicalstudyofMCD-386,itsleaddrugcandidateforAlzheimer’sdisease. The study produced encouraging results andMithridion is continuing todevelop thedrug for furtherPhaseIstudies.

Xunlight Corporation, a University of Toledo technologyspin-off,develops,manufactures,andmarketsphotovoltaicmodulesthatconvertsunlightintoelectricity.Thecompanyhascompletedinstallingitsfirstfull-scaleproductionline,andmadeitsfirstproductiondeliverytoTheUniversityofToledo. Xunlight recently received the Red Herring 100NorthAmericaAward,honoringthemostpromisingprivatetechnology companies, and the AlwaysOn GoingGreenEast 50 Award, honoring the top private companies incleantechpursuingextraordinaryinnovations.

Start-up ActivityInventors

TheFacultyatTheUniversityofToledohascontinuedtoembracetheUniversity’smissiontoimprovethehumancondition.Asaresult,ourofficesawa59percentincreaseinthenumberofinventiondisclosuressubmitted,whichresultedinadditionallicenses,start-upcompanies,andrevenues.

Medical 47%

Pharmacy1%

Arts & Sciences13%

Engineering 37%

Education1%

Business1%

Industry Sponsored Research, Material Transfer, and Confidentiality Agreements

108

145155

177

139

175

203

0

50

100

150

200

250

FY 2003 FY 2004 FY 2005 FY 2006 FY 2007 FY 2008 FY 2009

Invention Disclosures

24

34 35 3833

54

91

0

10

20

30

40

50

60

70

80

90

100

FY 2003 FY 2004 FY 2005 FY 2006 FY 2007 FY 2008 FY2009

Licensing Revenue

$150,434

$337,423

$901,114

$524,575

$865,018$939,307

$1,004,000

$0$200,000

$400,000

$600,000

$800,000

$1,000,000

$1,200,000

FY 2003 FY 2004 FY 2005 FY 2006 FY 2007 FY 2008 FY 2009

$1,200,000

$1,000,000

$800,000

$600,000

$400,000

$200,000

$0

Deals (Licenses and Options)

5

8

12

7

19

12

22

-

5

10

15

20

25

FY 2003 FY 2004 FY 2005 FY 2006 FY 2007 FY 2008 FY 2009

The University of Toledo has made a significant commitment to improve the human condition by taking a leadership role in regional economic development. To enable and strengthen these efforts, the University has taken major steps to build up the technology transfer program by adding new staff members to (i) assist in identifying and licensing new technologies and (ii) help develop new spin-off businesses. Lloyd Jacobs, M.D., President of the University, has clearly articulated that the technology transfer group is a core University unit performing highly valued functions with an established ability to identify and license new technologies and create spin-off businesses that result in jobs, economic development and wealth creation. In 2008, Innovation Associates reported in a project funded by the National Science Foundation, based on data from the Association of University Technology Managers (AUTM) that, among US universities, UT ranked 6th in executing licenses and 7th in launching start-up businesses, when taking the level of research expenditures into account — an indication of a very high level productivity in the translation of research into economic development. The US average for invention disclosures per $10 MM of research expenditures is 4.3. UT is significantly higher, increasing from 5.8 to 16 in the past seven years. The number of new license agreements per $10 MM of research expenditures has also increased steadily from 2003 to 2009, from 1.2 to 3.8, versus a national average of 0.4. According to AUTM, the average US University spins-off one business for every $100 MM in research expenditures. At two per year, UT is four times the national average and at three per year, the results in 2007 to 2009, UT is six times the national average. UT now has 16 active spin-off businesses, generating about 100 local technology positions. Several have attracted $1 million + in third party validation funding. Three spin-offs have received funding from Regional Growth Partnership’s Rocket Ventures and four have qualified for the Regional Growth Partnership’s Ignite Program. We look forward to continuing to work closely with the faculty on innovative and entrepreneurial ideas. We believe that the faculty’s continued participation will help us increase UT’s state-wide and national profile as an innovation system that produces new discoveries, new products and/or services, new firms, jobs, and wealth creation.

RichardAndaloroDonaldAngelbeckBernardArulanandamRaghebAssalyBradleyAustermillerKennethBachmannJamesBarilGloriaBorgstahlMichaelBrattainReneeBuchananJeffreyBurnhamJamesByersBrentCameronYangCaoKemingChenXiaChenGarryColeAlvinCompaanErinCrawfordJulianDaviesRobertDeckLaurentDelouxJefferyDeMuthXunmingDengJohnDignamPhilipDunbarGrahamDurantSylvainDutremezPaulErhardtErvinFaulmannRonaldFournierPeterFraleighJamesFryKuan-ChenFuJamesGanoGretaGarboDeanGiolandoVijayGoelPeterGoldblattStephenGoldmanBingGongAnneGravesAkhleshGupta

JiwanGuptaGeorgeHageageJamesHamptonGregoryHaselhuhnJudyHendricksJamesHornerWayneHossRichardHudsonChiung-YuHungJamesHuttnerClaraJacksonDouglasJambard-SweetJerzyJankunRalphJansenVictorKarpovStamatiosKartalopoulosPeterKascakRickKeckAminKhanRogerKingJonKirchhoffThoeKirklandIIIRitaKleinWieslawKlisCharlesKnightStevenKramerKennethKroppFrederickKurtzHaroldLeeAkliluLemmaMarcLevineJeffreyLovelaceEdwardLumsdaineXiandaMaKonstantinMakhratchevMauriceManningWilliamMesserJr.DennisMetzgerAlanMorganNaserMostaghelDurgeshNadkarniGanapathyNaganathanTerryNg

BabatundeOjoHenryPovolnyKentPriceDemetriosRaftopoulosWalajapetRajeswaranGlennReimerWilliamRollYannRoussillonSairamRudrabhatlaJeffreySabinMurraySaffranJeffreySarverPadmanabhanSekherStevenSelmanKalpathiSeshanJosephShapiroDianaShvydkaHenrySimonDimitrisSkalkosJamesSlamaCliffordSmithEdwardSnellMorrisSrebnikSujathaSrinivasanThomasStuartVernerSwansonSridharThirupathiLiyanaaratchingeTillekeratneJamesTrempeStefanUhlenbrockSasidharVaranasiYuWangDavidWeaverJamesWilleyJianminXueQichengYangZhongYeJieh-JuenYuQuilinYuBinZhengDonaldZrudsky

Gene ExpressJim WilleyJune 1998 Agenomicsbiotechcompanyprovidinggeneassaystoassistpharmaceuticalandbiotechcompanieswithdrugdevelopmentandexpressionanalysis.

Schneider & Morse Group Roy Schneider and Dennis Morse April 2001 Astart-upfocusedondevelopingcomputer-basededucationaltoolsforanimalanatomyanddissection

Mithridion Wayne Hoss and Bill Messer January 2002 Anemergingbiotechcompanyfocusedonthediscoveryandcommercializationoftreatmentsforneurologicalandpsychiatricdiseases

Innovative Thin Films, Ltd. Dean Giolando March 2004 Acompanyfocusedonprovidingthinfilmsolutionstoproblemsassociatedwiththephotovoltaicindustrysuchasscratching,soilingandreflection

Hi-Genomics Stephen Goldman and Sairam Rudrabhatla April 2004 Avirtualcompanywithtechnologiesintissuecultureandgenetictransformationthatcouplehighoutput,rapid,genotypeindependentregenerationtohighfrequencyDNAtransferusingeitheragrobacteriumorbiolistictransformation

The Turning Point Vijay Goel, Danny Pincivero, John Jaegly, and David Dick June 2005 Amanufacturingandmarketingfirmthatproducesastate-of-the-artgolfexerciseandtherapeuticdevice

Xunlight Xunming Deng January 2006 Amanufacturingandmarketingcompanythatdevelopsthin-filmsiliconbasedphotovoltaicproductsandmanufacturingequipmentforhigh-throughputproductionofflexibleandlightweightphotovoltaicmodulesatlowcost

Spinal DesignsAshok Biyani May 2006 Amarketingfirmthatprovidesproductsandservicestoorthopedicsurgeons.

Freedom Meditech Brent Cameron December 2006 Adevelopmentalstagemedicaldevicecompanyfocusedonthenon-invasivebloodglucosetestingfordiabetics

Suganit Systems Sasidhar Varanasi, Connie Schall, Jared Anderson, and Patricia Relue March 2007 Astart-upcompanyinvolvedintheresearchanddevelopmentofrenewableandcleanenergywithafocusinethanolproductionfrombiomass

ADS Biotechnology, Joseph Shapiro, David Dignam, and Ragheb Assaly January 2008 Revolutionaryapproachforthetreatmentofthreateningclinicalconditions.Thecompany’sprimaryproduct,pegylatedalbumin,isatherapeuticcolloid-typebloodvolumeexpanderagentthatissuperiortohumanserumalbumin

Esclapeus Biopharaceuticals KV Chin May 2008Start-upfocusedondevelopingasmallmoleculeinterventionforobesity,oneofthemostseriouspublichealthrisksintheUSandworldwide

Innovative Water Technologies Dean Giolando May 2008Developingaflashevaporationspraytechnologyforthepurificationand/ordesalinationofwater

Xunlight Solar-26 Al Compaan December 2008DevelopingCdTethin-filmphotovoltaicsonpolyimidesubstrates

Total Compliance Abdul-Majeed Azad February 2009 Start-upplanningtocommercializetechnologyfortheremovalofcarbonmonoxide,organiccompoundsandunburnedhydrocarbonsfromthestreamofcombustiondevicesand/orspraybooths.

JWH Group Abdul-Majeed Azad April 2009Start-upcompanythatisdevelopinggassensortechnology

The University would like to recognize the following University inventors’ contributions in promoting the progress of science through designation as an inventor on one or more patent grants. Names in red are new additions to the list for fiscal year 2009. ADSBiotechnology,Ltd,aUTspin-offcompany,isworking

tocommercializeanewmedicaltreatment,polyethylene-glycol (PEG)-modified albumin, which works to expandblood’svolumesoitwillnotescapeasmayoccurinvariousmedical scenarios where a patient’s blood vessels leak.The company worked with RocketVentures to organizeand secure funding, including a recent investment of$250,000.ADShas submitted applications for grants totheU.S.DepartmentofDefense,theNationalInstitutesofHealth,andtheClevelandClinic.

SuGanitSystems,Inc.,astart-upcompanyresearchingand developing renewable clean energy, acquiredexclusivelicensetotwoUniversityofToledotechnologiesfor producing ethanol from cellulosic biomass. Thecompany has been awarded over $2.1M in fundingfrom the US Department of Energy, USDA, and Ohio’sThird Frontier Advanced Energy Program to developthese technologies. SuGanit is scaling up the licensedtechnologyandisplanningtobuildapilotscalecellulosicethanolfacilityinToledo,Ohio.

Mithridion, Inc. merged with the UT spin-off CognitivePharmaceuticals to develop drugs for neurologicalandpsychiatricdiseases.Thecompanyhasraised$7.4milliontodateinequityfundingandrecentlyannouncedthe results of its Phase I pharmacokinetic and clinicalstudyofMCD-386,itsleaddrugcandidateforAlzheimer’sdisease. The study produced encouraging results andMithridion is continuing todevelop thedrug for furtherPhaseIstudies.

Xunlight Corporation, a University of Toledo technologyspin-off,develops,manufactures,andmarketsphotovoltaicmodulesthatconvertsunlightintoelectricity.Thecompanyhascompletedinstallingitsfirstfull-scaleproductionline,andmadeitsfirstproductiondeliverytoTheUniversityofToledo. Xunlight recently received the Red Herring 100NorthAmericaAward,honoringthemostpromisingprivatetechnology companies, and the AlwaysOn GoingGreenEast 50 Award, honoring the top private companies incleantechpursuingextraordinaryinnovations.

Start-up ActivityInventors

TheFacultyatTheUniversityofToledohascontinuedtoembracetheUniversity’smissiontoimprovethehumancondition.Asaresult,ourofficesawa59percentincreaseinthenumberofinventiondisclosuressubmitted,whichresultedinadditionallicenses,start-upcompanies,andrevenues.

Medical 47%

Pharmacy1%

Arts & Sciences13%

Engineering 37%

Education1%

Business1%

Industry Sponsored Research, Material Transfer, and Confidentiality Agreements

108

145155

177

139

175

203

0

50

100

150

200

250

FY 2003 FY 2004 FY 2005 FY 2006 FY 2007 FY 2008 FY 2009

Invention Disclosures

24

34 35 3833

54

91

0

10

20

30

40

50

60

70

80

90

100

FY 2003 FY 2004 FY 2005 FY 2006 FY 2007 FY 2008 FY2009

Licensing Revenue

$150,434

$337,423

$901,114

$524,575

$865,018$939,307

$1,004,000

$0$200,000

$400,000

$600,000

$800,000

$1,000,000

$1,200,000

FY 2003 FY 2004 FY 2005 FY 2006 FY 2007 FY 2008 FY 2009

$1,200,000

$1,000,000

$800,000

$600,000

$400,000

$200,000

$0

Deals (Licenses and Options)

5

8

12

7

19

12

22

-

5

10

15

20

25

FY 2003 FY 2004 FY 2005 FY 2006 FY 2007 FY 2008 FY 2009

The University of Toledo has made a significant commitment to improve the human condition by taking a leadership role in regional economic development. To enable and strengthen these efforts, the University has taken major steps to build up the technology transfer program by adding new staff members to (i) assist in identifying and licensing new technologies and (ii) help develop new spin-off businesses. Lloyd Jacobs, M.D., President of the University, has clearly articulated that the technology transfer group is a core University unit performing highly valued functions with an established ability to identify and license new technologies and create spin-off businesses that result in jobs, economic development and wealth creation. In 2008, Innovation Associates reported in a project funded by the National Science Foundation, based on data from the Association of University Technology Managers (AUTM) that, among US universities, UT ranked 6th in executing licenses and 7th in launching start-up businesses, when taking the level of research expenditures into account — an indication of a very high level productivity in the translation of research into economic development. The US average for invention disclosures per $10 MM of research expenditures is 4.3. UT is significantly higher, increasing from 5.8 to 16 in the past seven years. The number of new license agreements per $10 MM of research expenditures has also increased steadily from 2003 to 2009, from 1.2 to 3.8, versus a national average of 0.4. According to AUTM, the average US University spins-off one business for every $100 MM in research expenditures. At two per year, UT is four times the national average and at three per year, the results in 2007 to 2009, UT is six times the national average. UT now has 16 active spin-off businesses, generating about 100 local technology positions. Several have attracted $1 million + in third party validation funding. Three spin-offs have received funding from Regional Growth Partnership’s Rocket Ventures and four have qualified for the Regional Growth Partnership’s Ignite Program. We look forward to continuing to work closely with the faculty on innovative and entrepreneurial ideas. We believe that the faculty’s continued participation will help us increase UT’s state-wide and national profile as an innovation system that produces new discoveries, new products and/or services, new firms, jobs, and wealth creation.

RichardAndaloroDonaldAngelbeckBernardArulanandamRaghebAssalyBradleyAustermillerKennethBachmannJamesBarilGloriaBorgstahlMichaelBrattainReneeBuchananJeffreyBurnhamJamesByersBrentCameronYangCaoKemingChenXiaChenGarryColeAlvinCompaanErinCrawfordJulianDaviesRobertDeckLaurentDelouxJefferyDeMuthXunmingDengJohnDignamPhilipDunbarGrahamDurantSylvainDutremezPaulErhardtErvinFaulmannRonaldFournierPeterFraleighJamesFryKuan-ChenFuJamesGanoGretaGarboDeanGiolandoVijayGoelPeterGoldblattStephenGoldmanBingGongAnneGravesAkhleshGupta

JiwanGuptaGeorgeHageageJamesHamptonGregoryHaselhuhnJudyHendricksJamesHornerWayneHossRichardHudsonChiung-YuHungJamesHuttnerClaraJacksonDouglasJambard-SweetJerzyJankunRalphJansenVictorKarpovStamatiosKartalopoulosPeterKascakRickKeckAminKhanRogerKingJonKirchhoffThoeKirklandIIIRitaKleinWieslawKlisCharlesKnightStevenKramerKennethKroppFrederickKurtzHaroldLeeAkliluLemmaMarcLevineJeffreyLovelaceEdwardLumsdaineXiandaMaKonstantinMakhratchevMauriceManningWilliamMesserJr.DennisMetzgerAlanMorganNaserMostaghelDurgeshNadkarniGanapathyNaganathanTerryNg

BabatundeOjoHenryPovolnyKentPriceDemetriosRaftopoulosWalajapetRajeswaranGlennReimerWilliamRollYannRoussillonSairamRudrabhatlaJeffreySabinMurraySaffranJeffreySarverPadmanabhanSekherStevenSelmanKalpathiSeshanJosephShapiroDianaShvydkaHenrySimonDimitrisSkalkosJamesSlamaCliffordSmithEdwardSnellMorrisSrebnikSujathaSrinivasanThomasStuartVernerSwansonSridharThirupathiLiyanaaratchingeTillekeratneJamesTrempeStefanUhlenbrockSasidharVaranasiYuWangDavidWeaverJamesWilleyJianminXueQichengYangZhongYeJieh-JuenYuQuilinYuBinZhengDonaldZrudsky

Gene ExpressJim WilleyJune 1998 Agenomicsbiotechcompanyprovidinggeneassaystoassistpharmaceuticalandbiotechcompanieswithdrugdevelopmentandexpressionanalysis.

Schneider & Morse Group Roy Schneider and Dennis Morse April 2001 Astart-upfocusedondevelopingcomputer-basededucationaltoolsforanimalanatomyanddissection

Mithridion Wayne Hoss and Bill Messer January 2002 Anemergingbiotechcompanyfocusedonthediscoveryandcommercializationoftreatmentsforneurologicalandpsychiatricdiseases

Innovative Thin Films, Ltd. Dean Giolando March 2004 Acompanyfocusedonprovidingthinfilmsolutionstoproblemsassociatedwiththephotovoltaicindustrysuchasscratching,soilingandreflection

Hi-Genomics Stephen Goldman and Sairam Rudrabhatla April 2004 Avirtualcompanywithtechnologiesintissuecultureandgenetictransformationthatcouplehighoutput,rapid,genotypeindependentregenerationtohighfrequencyDNAtransferusingeitheragrobacteriumorbiolistictransformation

The Turning Point Vijay Goel, Danny Pincivero, John Jaegly, and David Dick June 2005 Amanufacturingandmarketingfirmthatproducesastate-of-the-artgolfexerciseandtherapeuticdevice

Xunlight Xunming Deng January 2006 Amanufacturingandmarketingcompanythatdevelopsthin-filmsiliconbasedphotovoltaicproductsandmanufacturingequipmentforhigh-throughputproductionofflexibleandlightweightphotovoltaicmodulesatlowcost

Spinal DesignsAshok Biyani May 2006 Amarketingfirmthatprovidesproductsandservicestoorthopedicsurgeons.

Freedom Meditech Brent Cameron December 2006 Adevelopmentalstagemedicaldevicecompanyfocusedonthenon-invasivebloodglucosetestingfordiabetics

Suganit Systems Sasidhar Varanasi, Connie Schall, Jared Anderson, and Patricia Relue March 2007 Astart-upcompanyinvolvedintheresearchanddevelopmentofrenewableandcleanenergywithafocusinethanolproductionfrombiomass

ADS Biotechnology, Joseph Shapiro, David Dignam, and Ragheb Assaly January 2008 Revolutionaryapproachforthetreatmentofthreateningclinicalconditions.Thecompany’sprimaryproduct,pegylatedalbumin,isatherapeuticcolloid-typebloodvolumeexpanderagentthatissuperiortohumanserumalbumin

Esclapeus Biopharaceuticals KV Chin May 2008Start-upfocusedondevelopingasmallmoleculeinterventionforobesity,oneofthemostseriouspublichealthrisksintheUSandworldwide

Innovative Water Technologies Dean Giolando May 2008Developingaflashevaporationspraytechnologyforthepurificationand/ordesalinationofwater

Xunlight Solar-26 Al Compaan December 2008DevelopingCdTethin-filmphotovoltaicsonpolyimidesubstrates

Total Compliance Abdul-Majeed Azad February 2009 Start-upplanningtocommercializetechnologyfortheremovalofcarbonmonoxide,organiccompoundsandunburnedhydrocarbonsfromthestreamofcombustiondevicesand/orspraybooths.

JWH Group Abdul-Majeed Azad April 2009Start-upcompanythatisdevelopinggassensortechnology

The University would like to recognize the following University inventors’ contributions in promoting the progress of science through designation as an inventor on one or more patent grants. Names in red are new additions to the list for fiscal year 2009. ADSBiotechnology,Ltd,aUTspin-offcompany,isworking

tocommercializeanewmedicaltreatment,polyethylene-glycol (PEG)-modified albumin, which works to expandblood’svolumesoitwillnotescapeasmayoccurinvariousmedical scenarios where a patient’s blood vessels leak.The company worked with RocketVentures to organizeand secure funding, including a recent investment of$250,000.ADShas submitted applications for grants totheU.S.DepartmentofDefense,theNationalInstitutesofHealth,andtheClevelandClinic.

SuGanitSystems,Inc.,astart-upcompanyresearchingand developing renewable clean energy, acquiredexclusivelicensetotwoUniversityofToledotechnologiesfor producing ethanol from cellulosic biomass. Thecompany has been awarded over $2.1M in fundingfrom the US Department of Energy, USDA, and Ohio’sThird Frontier Advanced Energy Program to developthese technologies. SuGanit is scaling up the licensedtechnologyandisplanningtobuildapilotscalecellulosicethanolfacilityinToledo,Ohio.

Mithridion, Inc. merged with the UT spin-off CognitivePharmaceuticals to develop drugs for neurologicalandpsychiatricdiseases.Thecompanyhasraised$7.4milliontodateinequityfundingandrecentlyannouncedthe results of its Phase I pharmacokinetic and clinicalstudyofMCD-386,itsleaddrugcandidateforAlzheimer’sdisease. The study produced encouraging results andMithridion is continuing todevelop thedrug for furtherPhaseIstudies.

Xunlight Corporation, a University of Toledo technologyspin-off,develops,manufactures,andmarketsphotovoltaicmodulesthatconvertsunlightintoelectricity.Thecompanyhascompletedinstallingitsfirstfull-scaleproductionline,andmadeitsfirstproductiondeliverytoTheUniversityofToledo. Xunlight recently received the Red Herring 100NorthAmericaAward,honoringthemostpromisingprivatetechnology companies, and the AlwaysOn GoingGreenEast 50 Award, honoring the top private companies incleantechpursuingextraordinaryinnovations.

Start-up ActivityInventors

TheFacultyatTheUniversityofToledohascontinuedtoembracetheUniversity’smissiontoimprovethehumancondition.Asaresult,ourofficesawa59percentincreaseinthenumberofinventiondisclosuressubmitted,whichresultedinadditionallicenses,start-upcompanies,andrevenues.

Medical 47%

Pharmacy1%

Arts & Sciences13%

Engineering 37%

Education1%

Business1%

Industry Sponsored Research, Material Transfer, and Confidentiality Agreements

108

145155

177

139

175

203

0

50

100

150

200

250

FY 2003 FY 2004 FY 2005 FY 2006 FY 2007 FY 2008 FY 2009

Invention Disclosures

24

34 35 3833

54

91

0

10

20

30

40

50

60

70

80

90

100

FY 2003 FY 2004 FY 2005 FY 2006 FY 2007 FY 2008 FY2009

Licensing Revenue

$150,434

$337,423

$901,114

$524,575

$865,018$939,307

$1,004,000

$0$200,000

$400,000

$600,000

$800,000

$1,000,000

$1,200,000

FY 2003 FY 2004 FY 2005 FY 2006 FY 2007 FY 2008 FY 2009

$1,200,000

$1,000,000

$800,000

$600,000

$400,000

$200,000

$0

Deals (Licenses and Options)

5

8

12

7

19

12

22

-

5

10

15

20

25

FY 2003 FY 2004 FY 2005 FY 2006 FY 2007 FY 2008 FY 2009

T E C H N O L O G Y T R A N S F E R

ADVANCING INNOVATION AND ENTREPRENEURSHIP

U T I N N O VAT I O N E N T E R P R I S E S

A N N U A L R E P O RT O N T E C H N O L O G Y T R A N S F E RFiscal Year 2009

Martin Abraham• Anovelsulfur-tolerantcatalystforsteamreformingofdiesel

andjetfuel

Malabala Adiga• Methodofplatingelectrocatalystforhydrogengeneration

Jared Anderson, Fei Zhao, Yunjing Meng, Zhao Qi Chao• Polymericionicliquidsasabsorbentcoatingsinsolidphase

microextraction

Ragheb Assaly, Joseph Shapiro, John Dignam• UseofPEG-Albuminasaplatformfordeliveryofantioxidant

andothermedications

Abdul-Majeed Azad• Carbondioxideandwater-basedfuelcells• HighTemperatureSulfurSorbents(ZSeries)• Carbondioxideandwater-basedfuelcells

Abdul-Majeed Azad, Desikan Sundararajan• Exhaustgaspurificationcatalysts• Acetylenegassensor

Michael Bisesi, Christopher Bork, Paul Rega • Cot-AID(AssistiveIntegratedDevices)(11separatedevicesdisclosed)

Ashok Biyani• Modifiedpediclescrewtipforone-steppercutaneousinsertion• Unidirectionalrotarypediclescrewforcorrectionofspinaldeformity

ingrowingchildren• Directionalsofttissuedilatorsanddockingpinwithintegratedlight

sourceforoptimizationofretractorplacementinminimallyinvasivespinesurgery

• Derotationpediclescrewdesignforsurgicalcorrectionofspinaldeformity

• Fixedandpreloadcompressioncervicalplateswithandwithoutintegratedlockingmechanism

• Posteriorfixationdeviceforpercutaneousstabilizationofthoracolumbarburstfractures

• Expandablecorpectomycageconcept

Ashok Biyani, Philip Nowicki• Femoralneckwasherfixationsystem

Ashok Biyani, Brian Blessinger• Anintegrateddeviceforstorageanddeliveryofbonegraftor

implantablematerial

Ashok Biyani, Gary Durivage• AdjustableHeightPedicleScrew

Christopher Bork• Anergonomichandleforrollingluggage

Thomas Cable, John Setlock• Reformerdesignusingsymmetrical,oxygenconductivemembranes

Brent Cameron, Scott Pappada• Aneuralnetworkbasedapproachforphysiologicalglycemic

forecasting

George Cicila, Soon Jin Lee, Justin Ways• Congenicratstrains(6separatestrainsdisclosed)

Maria Coleman, Hamidreza Hakimelahi, Javed Mapkar• Functionalnanocompositenetworkforreverseselectivemembranes

Alvin Compaan• RapidthermalactivationofflexibleCdTecellsandmodules• Methodtoimproveadhesionofthin-filmsolarcellcoatingsto

polymerfilm• MethodtomakeflexibleCdTemodulesonpolymercastonstainless

steelwebforroll-to-rollmanufacturing

Christopher Cooper• Vascularqualityassurance

Xunming Deng, Qi Hua Fan, Shiban Zhang• PulsedDCreactivesputteringdepositionofzincoxidethinfilmsfrom

zincmetaltarget

Michael Dennis, Dean Walton• ScatterreductioninEPIDradiography

John Dismukes, Lawrence Miller, John Bers• ARImethodologyandscorecardtoolforacceleratingbreakthrough

innovations

Mohammad Elahinia, James Maloney, Majid Tabesh, Richard Yeasting• Bio-inspiredshapememoryalloyesophaguspositioner

Mohammad Elahinia, Vijay Goel, Majid Tabesh• Bio-inspiredshapememoryalloypediclescrewtocompensateforbone

degradationinosteoporosispatients

Mohammad Elahinia, The Nguyen• Mixed-modesemiactivemagnetorheologicalmount

Qi Hua Fan, Xianbo Liao, Xunming Deng, Xianbi Xiang• Highefficiencythinfilmsolarcellsmadewithgradedlightabsorber

materials

Vijay Goel, Hossein Elgafy, Ahmad Faizan• Cervicalspineposteriordynamicsysteminconjunctionwithanartificial

disctotreatthewhiplashinjurypatients

Vijay Goel, Aaron Matyas• Anchoringpediclescrew• Minimallyinvasivecollapsiblecage

Miles Hacker• Usinginactiveanti-cancerdrugstotreatcysticfibrosis

Marthe Howard• Innovativenewtreatmentstrategyforglioma

Dragan Isailovic• Florophore-assistedlaserdesorptionionizationmassspectrometry

(FALDI-MS)

Samer Khouri, Sonia Najjar• Novelmodelofthemetabolicsyndromewithassociatedspontaneous

atherosclerosis

Dong-Shik Kim, Maria Coleman• SuspensiontechniqueforGochangyellowclay

Tony Koesters, Brian Kanney, Ryan Kremer, Allan Gindy, Faisal Bukhari• BurnableShreddedPaperLogs

Yun-Ming Lin• Reactionrateaccelerationviaasymmetricbifunctionalcatalysis

Terri Lombardo• Novelrenewableelectricenergy

Ioan Marinescu• Penetratingcompoundswithvariableproperties

Mark Mason• Newtrianionicligandsforconstrainedgeometrycatalysts

Udayan Nadkeolyar• Pilotfreehighspeedsurfacetransportationcapsule

Philip Nowicki, Ashok Biyani, Martin Skie• Antibioticclusteredpercutaneouspincoversystem

Thomas Papadimos• Thebeneficialeffectsofinhalednitricoxideinpatientswithsevere

traumaticbraininjurycomplicatedbyacuterespiratorydistresssyndrome

Invention DisclosuresCatherine Powell• MARKtheSpot–Answersonthespot• Backlace

Carmen Quatman, Andrew Maszaros, Catherine Quatman• Shoulderbracefordecreasedpassiverestraints

Martin Rice• Learningtotelltimeusingknowledgeofresults

Edwin Sanchez, Garrett Heinrich, Terry Hinds• Discoveryofglucocorticoidreceptorbetainmice

Rebecca Schneider• ALearningCommunityofTeachers(ALCOT)

Steven Selman, Hinman Channing• Applicationsofcobratoxinandderivatives

Lirim Shemshedini, Changmeng Cai, Shao-Yong Chen, Chen-Lin Hsieh• Solubleguanylylcyclasealpha1(sGCalpha1)asanoveldiagnostic

markerofandthereapeutictargetforprostatecancer• V94Cells:Anovelandrogen-independentLNCaPcellline

Krishna Shenai, Nikhil Gudi, Dhakshina Thavamani• Anovelhybridthermoelectricenergyconverter(TEC)andphotovoltaic

(PV)system

Krishna Shenai, Nikhil Gudi, Dhakshina Thavamani, Premchand Boyapati, Prashanth Reddy• HybridsmartmodularDCpowersystem

Krishna Shenai, Nikhil Gudi• Wirelesssmartmovableantenna• Remotelycontrollablesmartwidebandwirelessantenna• Smartwirelesslytunablecommunicationsystempowerfrom

renewableenergysources

Krishna Shenai, Ashok Biyani, Vijay Goel, Vijay Devabhaktuni, Bradford Lilly• Anovelprocedureandapparatusforperforminghighly

accuratesurgery

Krishna Shenai, Premchand Boyapati, Dhakshina Thavamani, Jessica Jordan• Novelwirelesssensorcommunicationusingsoundwaves

Krishna Shenai, Premchand Boyapati• Multi-functionlow-powerwirelessairsensor• Smartremotesensingandwirelessinformationmanagement• Anovelwirelesssensorsystemforstructuralhealthmonitoring

Krishna Shenai, Bradford Lilly, Premchand Boyapati• Automatedswimmingpoolmanagementsystem• Amethodforpreciseintelligentsoilchemicaldistribution

Thomas Stuart• Amodularizedsystemwithrelaysformanagingseriesconnected

batterycells

Zi-Jian Xie Jiang Tian• Na/K-ATPaseexpressionasanindicatorfortreatmentofcancer

Zi-Jian Xie, Joseph Shapiro, Zhichuan Li• Na/K-ATPase-derivedpeptidesasantagonistofCTSandas

therapeuticagentsforcancer

Daniel Kory, Ph.D., MBAAssociate Vice President for Technology TransferPhone: 419.383.6924Email: [email protected]

Stephen Snider, J.D.Director, Technology Licensing & Contracts Phone: 419.383.6963

Email: [email protected]

Mark Fox, J.D., MSPatent Technology AssociatePhone: 419.383.6907Email: [email protected]

Samuel Giles, MBAPatent Licensing AssociatePhone: 419.383.6965Email: [email protected]

Sandra RhoadesIP AdministratorPhone: 419.383.6923Email: [email protected]

Contacts

INNOVATIONENTERPRISES

INNOVATIONENTERPRISES

W W W. U T O L E D O . E D U / R E S E A R C H / T E C H T R A N S F E R

IR 1

92 1

009

250

In2009,UTInnovationEnterpriseswascreatedtodiversifyandtransformtheregionaleconomybyfacilitatingthedevelopmentandattractionofscienceandtechnology-basedorganizations.Bybringingtogetherresearchdevelopment,technologytransfer,incubation,workforcedevelopmentandtheScienceandTechnologyCorridor,theUniversitybelievesitwillbeabletoenhancetheglobalcompetitivenessofNWOhio.

T E C H N O L O G Y T R A N S F E R

ADVANCING INNOVATION AND ENTREPRENEURSHIP

U T I N N O VAT I O N E N T E R P R I S E S

A N N U A L R E P O RT O N T E C H N O L O G Y T R A N S F E RFiscal Year 2009

Martin Abraham• Anovelsulfur-tolerantcatalystforsteamreformingofdiesel

andjetfuel

Malabala Adiga• Methodofplatingelectrocatalystforhydrogengeneration

Jared Anderson, Fei Zhao, Yunjing Meng, Zhao Qi Chao• Polymericionicliquidsasabsorbentcoatingsinsolidphase

microextraction

Ragheb Assaly, Joseph Shapiro, John Dignam• UseofPEG-Albuminasaplatformfordeliveryofantioxidant

andothermedications

Abdul-Majeed Azad• Carbondioxideandwater-basedfuelcells• HighTemperatureSulfurSorbents(ZSeries)• Carbondioxideandwater-basedfuelcells

Abdul-Majeed Azad, Desikan Sundararajan• Exhaustgaspurificationcatalysts• Acetylenegassensor

Michael Bisesi, Christopher Bork, Paul Rega • Cot-AID(AssistiveIntegratedDevices)(11separatedevicesdisclosed)

Ashok Biyani• Modifiedpediclescrewtipforone-steppercutaneousinsertion• Unidirectionalrotarypediclescrewforcorrectionofspinaldeformity

ingrowingchildren• Directionalsofttissuedilatorsanddockingpinwithintegratedlight

sourceforoptimizationofretractorplacementinminimallyinvasivespinesurgery

• Derotationpediclescrewdesignforsurgicalcorrectionofspinaldeformity

• Fixedandpreloadcompressioncervicalplateswithandwithoutintegratedlockingmechanism

• Posteriorfixationdeviceforpercutaneousstabilizationofthoracolumbarburstfractures

• Expandablecorpectomycageconcept

Ashok Biyani, Philip Nowicki• Femoralneckwasherfixationsystem

Ashok Biyani, Brian Blessinger• Anintegrateddeviceforstorageanddeliveryofbonegraftor

implantablematerial

Ashok Biyani, Gary Durivage• AdjustableHeightPedicleScrew

Christopher Bork• Anergonomichandleforrollingluggage

Thomas Cable, John Setlock• Reformerdesignusingsymmetrical,oxygenconductivemembranes

Brent Cameron, Scott Pappada• Aneuralnetworkbasedapproachforphysiologicalglycemic

forecasting

George Cicila, Soon Jin Lee, Justin Ways• Congenicratstrains(6separatestrainsdisclosed)

Maria Coleman, Hamidreza Hakimelahi, Javed Mapkar• Functionalnanocompositenetworkforreverseselectivemembranes

Alvin Compaan• RapidthermalactivationofflexibleCdTecellsandmodules• Methodtoimproveadhesionofthin-filmsolarcellcoatingsto

polymerfilm• MethodtomakeflexibleCdTemodulesonpolymercastonstainless

steelwebforroll-to-rollmanufacturing

Christopher Cooper• Vascularqualityassurance

Xunming Deng, Qi Hua Fan, Shiban Zhang• PulsedDCreactivesputteringdepositionofzincoxidethinfilmsfrom

zincmetaltarget

Michael Dennis, Dean Walton• ScatterreductioninEPIDradiography

John Dismukes, Lawrence Miller, John Bers• ARImethodologyandscorecardtoolforacceleratingbreakthrough

innovations

Mohammad Elahinia, James Maloney, Majid Tabesh, Richard Yeasting• Bio-inspiredshapememoryalloyesophaguspositioner

Mohammad Elahinia, Vijay Goel, Majid Tabesh• Bio-inspiredshapememoryalloypediclescrewtocompensateforbone

degradationinosteoporosispatients

Mohammad Elahinia, The Nguyen• Mixed-modesemiactivemagnetorheologicalmount

Qi Hua Fan, Xianbo Liao, Xunming Deng, Xianbi Xiang• Highefficiencythinfilmsolarcellsmadewithgradedlightabsorber

materials

Vijay Goel, Hossein Elgafy, Ahmad Faizan• Cervicalspineposteriordynamicsysteminconjunctionwithanartificial

disctotreatthewhiplashinjurypatients

Vijay Goel, Aaron Matyas• Anchoringpediclescrew• Minimallyinvasivecollapsiblecage

Miles Hacker• Usinginactiveanti-cancerdrugstotreatcysticfibrosis

Marthe Howard• Innovativenewtreatmentstrategyforglioma

Dragan Isailovic• Florophore-assistedlaserdesorptionionizationmassspectrometry

(FALDI-MS)

Samer Khouri, Sonia Najjar• Novelmodelofthemetabolicsyndromewithassociatedspontaneous

atherosclerosis

Dong-Shik Kim, Maria Coleman• SuspensiontechniqueforGochangyellowclay

Tony Koesters, Brian Kanney, Ryan Kremer, Allan Gindy, Faisal Bukhari• BurnableShreddedPaperLogs

Yun-Ming Lin• Reactionrateaccelerationviaasymmetricbifunctionalcatalysis

Terri Lombardo• Novelrenewableelectricenergy

Ioan Marinescu• Penetratingcompoundswithvariableproperties

Mark Mason• Newtrianionicligandsforconstrainedgeometrycatalysts

Udayan Nadkeolyar• Pilotfreehighspeedsurfacetransportationcapsule

Philip Nowicki, Ashok Biyani, Martin Skie• Antibioticclusteredpercutaneouspincoversystem

Thomas Papadimos• Thebeneficialeffectsofinhalednitricoxideinpatientswithsevere

traumaticbraininjurycomplicatedbyacuterespiratorydistresssyndrome

Invention DisclosuresCatherine Powell• MARKtheSpot–Answersonthespot• Backlace

Carmen Quatman, Andrew Maszaros, Catherine Quatman• Shoulderbracefordecreasedpassiverestraints

Martin Rice• Learningtotelltimeusingknowledgeofresults

Edwin Sanchez, Garrett Heinrich, Terry Hinds• Discoveryofglucocorticoidreceptorbetainmice

Rebecca Schneider• ALearningCommunityofTeachers(ALCOT)

Steven Selman, Hinman Channing• Applicationsofcobratoxinandderivatives

Lirim Shemshedini, Changmeng Cai, Shao-Yong Chen, Chen-Lin Hsieh• Solubleguanylylcyclasealpha1(sGCalpha1)asanoveldiagnostic

markerofandthereapeutictargetforprostatecancer• V94Cells:Anovelandrogen-independentLNCaPcellline

Krishna Shenai, Nikhil Gudi, Dhakshina Thavamani• Anovelhybridthermoelectricenergyconverter(TEC)andphotovoltaic

(PV)system

Krishna Shenai, Nikhil Gudi, Dhakshina Thavamani, Premchand Boyapati, Prashanth Reddy• HybridsmartmodularDCpowersystem

Krishna Shenai, Nikhil Gudi• Wirelesssmartmovableantenna• Remotelycontrollablesmartwidebandwirelessantenna• Smartwirelesslytunablecommunicationsystempowerfrom

renewableenergysources

Krishna Shenai, Ashok Biyani, Vijay Goel, Vijay Devabhaktuni, Bradford Lilly• Anovelprocedureandapparatusforperforminghighly

accuratesurgery

Krishna Shenai, Premchand Boyapati, Dhakshina Thavamani, Jessica Jordan• Novelwirelesssensorcommunicationusingsoundwaves

Krishna Shenai, Premchand Boyapati• Multi-functionlow-powerwirelessairsensor• Smartremotesensingandwirelessinformationmanagement• Anovelwirelesssensorsystemforstructuralhealthmonitoring

Krishna Shenai, Bradford Lilly, Premchand Boyapati• Automatedswimmingpoolmanagementsystem• Amethodforpreciseintelligentsoilchemicaldistribution

Thomas Stuart• Amodularizedsystemwithrelaysformanagingseriesconnected

batterycells

Zi-Jian Xie Jiang Tian• Na/K-ATPaseexpressionasanindicatorfortreatmentofcancer

Zi-Jian Xie, Joseph Shapiro, Zhichuan Li• Na/K-ATPase-derivedpeptidesasantagonistofCTSandas

therapeuticagentsforcancer

Daniel Kory, Ph.D., MBAAssociate Vice President for Technology TransferPhone: 419.383.6924Email: [email protected]

Stephen Snider, J.D.Director, Technology Licensing & Contracts Phone: 419.383.6963

Email: [email protected]

Mark Fox, J.D., MSPatent Technology AssociatePhone: 419.383.6907Email: [email protected]

Samuel Giles, MBAPatent Licensing AssociatePhone: 419.383.6965Email: [email protected]

Sandra RhoadesIP AdministratorPhone: 419.383.6923Email: [email protected]

Contacts

INNOVATIONENTERPRISES

INNOVATIONENTERPRISES

W W W. U T O L E D O . E D U / R E S E A R C H / T E C H T R A N S F E R

IR 1

92 1

009

250

In2009,UTInnovationEnterpriseswascreatedtodiversifyandtransformtheregionaleconomybyfacilitatingthedevelopmentandattractionofscienceandtechnology-basedorganizations.Bybringingtogetherresearchdevelopment,technologytransfer,incubation,workforcedevelopmentandtheScienceandTechnologyCorridor,theUniversitybelievesitwillbeabletoenhancetheglobalcompetitivenessofNWOhio.