2009-2010 Course Selection Book

2 0 1 0 - 2 0 1 1 C O U R S E S

College of graduate StudieS

Table of ContentsAcademic Calendar 1New York State Law - Section 224A 3Registration Information 4Registration Instructions 6

ID Cards . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 6Car Registration and Parking . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 6Student Health . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 6Health Insurance . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 6Veteran’s Educational Benefits . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 6Special Students (Non-matriculated) . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 6Agreement between United University Professions and the State of New York 1982-85: Article 36 .1 Program for Tuition Assistance . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 7Syracuse University (SU) and COES&F Students . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 7Family Educational Rights and Privacy Act . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 7

Core Curriculum 9Foundations of Molecular and Cellular Biology GS616 . . . . . . . 4 Credit Hours 11Introduction to Applied Biostatistics and Research Design GS617 . . . . . . . 2 Credit Hours 11Responsible Conduct of Scientific Research (Research Ethics) I GS618 . . . . . . . . . . . . 1 credit 12Responsible Conduct of Scientific Research (Research Ethics) II GS619 . . . . . . . . . . . . 1 credit 12Graduate Student Research Opportunities GS604 . . . . . . 0 Credit Hours 13Biomedical Sciences Laboratory Rotations GS612 . . . 2 Credit Hours/rotation 13Introduction To The Presentation And Analysis Of Scientific Literature: Journal Club GS892 . . . . . . . . 1 Credit Hour 13

Biochemistry And Molecular Biology 14Biochemistry & Molecular Biology Laboratory Rotations B609 . . . . . . . 2 Credit Hours 14Methods Of Biochemistry And Molecular Biology Research B617 . . . . . . . . Variable Credit 14Biochemistry Seminar B620 . . . . . . . 0 Credit Hours 14Independent Studies In Biochemistry And Molecular Biology B638 . . . . 1 – 3 Variable Credit 14Gene Expression and Epigenetic Regulation B647 . . . . . . . 3 Credit Hours 15Research Design in Biochemistry & Molecular Biology B648 . . . . . . . 3 credits 15Topics in Quantitative Biology (2 hr sessions/every other week) B649 . . . . . . . . . . . . 1 credit 15Scientific Writing in Biochemistry B650 . . . . . . . . 1 Credit Hour 16Protein Sorting and Vesicular Trafficking B664 . . . . . . . . 1 Credit Hour 16Bioenergetics of Energy Transducing Membranes B665 . . . . . . . 2 Credit Hours 16Protein Structure Determination B666 . . . . . . . 2 Credit Hours 16Research In Biochemistry B700 . . . . . . . Variable Credit 16

SB3 17Biological and Medical Physics (SU: PHY 615) B611 . . . . . . . . 3 Credit Hours 17Biochemistry I B618 . . . . . . . . 3 Credit Hours 17Molecular Biology Techniques B619 . . . . . . . . 3 Credit Hours 17Biochemical Methods for Structural Biophysics B626 . . . . . . . 3 Credit Hours 18Molecular spectroscopy and structure (SU: CHE 546) B637 . . . . . . . 3 Credit Hours 18Molecular Basis of Evolution B639 . . . . . . . 3 Credit Hours 18Plant Biotechnology B640 . . . . . . . 3 Credit Hours 18Introduction to SB3 Research B652 . . . . . . . 2 Credit Hours 18

Molecular Modeling (SU: BCM684) B654 . . . . . . . 3 Credit Hours 19SB3 Journal Club (SU: BCM630) B655 . . . . . . . . 1 Credit Hour 19

Cell and Developmental Biology 20Human Anatomy A505 . . . . . . . 9 Credit Hours 20Introduction To Neuroscience (Same as N507) A507 . . . . . . . 3 Credit Hours 20Microscopic Anatomy A517 . . . . . . . 4 Credit Hours 20Graduate Cellular Anatomy A613 . . . . . . . . . . . . 2 Credits 21Contemporary Cellular, Molecular And Developmental Biology A614 . . . . . . . 3 Credit Hours 21Special Topics In Anatomical Sciences A615 . . . . . . . . Variable Credit 21Methods Of Cell & Developmental Research (Maximum Of 12 Credit Hours) A617 . . . . . . . . Variable Credit 22Neuroanatomy Lab (Same As N621) A621 . . . . . . . 2 Credit Hours 22Research In Cell & Developmental Biology A700 . . . . . . . Variable Credit 22

Microbiology and Immunology 23Medical Microbiology M510 . . . . . . . 7 Credit Hours* 23Problems In Cellular And Molecular Immunology M610 . . . . . . . 3 Credit Hours 23Current Concepts In Virology M616 . . . . . . . 3 Credit Hours 23Directed Individual Study In Microbiological And Immunological Research Methods M623 . . . . . . . Variable Credit 23Seminar And Journal Club In Microbiology And Immunology M624 . . . . . . . 2 Credit Hours 24Methods Of Microbiology And Immunology Research M626 . . . . . . . Variable Credit 24Introduction To Virology M627 . . . . . . . 2 Credit Hours 24Introduction To Immunology M628 . . . . . . . 2 Credit Hours 24Research In Microbiology M700 . . . . . . . Variable Credit 24

M D and Ph D Courses 25Research Design for Physician-Scientists MDPH 601 . . . . 3 Credit Hours 25

Neuroscience 25Introduction To Neuroscience (Same As A507) N507 . . . . . . . 3 Credit Hours 25Neuroscience (SU: ECS NEU 601) N601 . . . . . . . 3 Credit Hours 25Cell Physiology Of Excitable Cells (Same As PHA602 & PHY602) N602 . . . . . . . 2 Credit Hours 26Topics In Signaling In The Autonomic And Central Nervous Systems N603 . . . . . . . 2 Credit Hours 26Topics In Developmental Neurobiology N610 . . . . . . . 2 Credit Hours 26Topics In Vision I N616 . . . . . . . 2 Credit Hours 27Methods Of Neuroscience Research N617 . . . . . . . Variable Credit 27Topics In Vision II N618 . . . . . . . 2 Credit Hours 27Neurobiology Of Disease N619 . . . . . . . 2 Credit Hours 27Advanced Topics In Receptors And Cell Signaling (Same As PHY620) N620 . . . . . . . . 1 Credit Hour 28Neuroanatomy Lab (Same As A621) N621 . . . . . . . 2 Credit Hours 28Critical Analysis Of Neuroscience Communications N622 . . . . . . . . . . . . . . . . . 28 ½ Credit/ Semester, 1 Credit/Academic Year Systems Neuroscience N623 . . . . . . . 3 Credit Hours 28Topics In Cellular And Molecular Neurobiology N653 . . . . . . . 2 Credit Hours 29Topics In Sensory Systems N654 . . . . . . . 2 Credit Hours 29Research Rotations In Neuroscience N675 . . . . . . 1-5 Credit Hours 29Research In Neuroscience N700 . . . . . . . Variable Credit 29

Pharmacology 30Pharmacology PHA540 . . . . . 7 Credit Hours* 30Cell Physiology Of Excitable Cells (Same As N602 & Phy602) PHA602 . . . . . 2 Credit Hours 30Principles Of Pharmacology PHA610 . . . . . . . 1 Credit Hour 30Cardiovascular Physiology And Pharmacology PHA612 . . . . . . . 1 Credit Hour 30

Apoptosis And Cancer Pharmacology PHA615 . . . . . . . 2 Credit Hour 31Methods Of Pharmacology Research PHA617 . . . . . . Variable Credit 31Current Topics In Pharmacology PHA618 . . . . . . . 1 Credit Hour 31Autonomic Pharmacology PHA619 . . . . . . . 1 Credit Hour 31Cancer Biology And Therapeutics PHA621 . . . . . . . . . . . 1 Credit 31Pharmacology Seminar PHA645 . . . . . 0 Credit Hours 32Pharmacology Laboratory Rotations PHA653 . . . . . . Variable Credit 32Research In Pharmacology PHA700 . . . . . Variable Credit 32

Physiology Program 32Cell Physiology Of Excitable Cells (Same As N602 & PHA602) PHY602 . . . . . . 2 Credit Hours 32Biomaterials And Medical Devices (SU Course BEN468/668) PHY603 . . . . . . 2 Credit Hours 33Methods Of Physiology Research PHY617 . . . . . . . . Variable Credit 33Advanced Topics In Receptors And Cell Signaling (Same As N620) PHY620 . . . . . . . 1 Credit Hour 33Journal Club In Physiology PHY652 . . . . . . . 1 Credit Hour 34Systems Physiology PHY657 . . . . . . 6 Credit Hours 34Directed Individual Study In Physiological Research Methods PHY658 . . . . . . Variable Credit 34Physiology Seminar PHY659 . . . . . . . 1 Credit Hour 34Research In Physiology PHY700 . . . . . . Variable Credit 34

Additional Courses 35Grant Writing GS605 . . . . . . 3 Credit Hours 35Systems Biology Of Genetics, Genomics And Proteomics GS628 . . . . . . . 4 Credit Hours 35Spreadsheet Analysis Of Biological Data GS657 . . . . . . . 3 Credit Hours 36Ethics And The Health Professions CCFM6402 . . . 3 Credit Hours 36Disability, Medicine, And Representation CCFM6417 . . . . . . . . 3 Credits 36Medicine In Literature And Film CCFM6423 . . . . . . . . 3 Credits 37Orthopedic Basic Science OBS610 . . 1 Credit Hours Hour/Semester 37

1Academic Calendar

SUNY UPSTATE MEDICAL UNIVERSITY ACADEMIC CALENDAR 2010-2011

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10 All Mon June 7 Gross Anatomy, DPT and Early Admits Orientation and Fall Semester BeginsCOM Tues July 6 Clinical Orientation MS III (Required)COM/CHP Tues July 6 Med Scholars 2nd Year, MS III & MS IV Fall Semester BeginsCOGS Jul 19 - Jul 30 Fall Semesster Open Enrollment - Matriculated StudentsAll Wed Aug 18 Orientation Begins all New StudentsAll Mon Aug 23 FALL SEMESTER Begins (except as otherwise noted)COGS/CHP/CON Mon Aug 23 Registration Begins - Non-Matriculated StudentsCHP Fri Aug 27 College of Health Profession Program on HIV, TB and HepatitsCOGS/CHP/CON Mon Aug 30 30% Tuition Liability for full semester coursesCOGS/CHP/CON Fri Sept 3 Last Day to Add or Drop courses without a late feeCHP/CON Fri Sept 3 Last Day to Drop a full semester course without a gradeAll Mon Sept 6 Labor Day - No Classes - Clinics ClosedCOGS/CHP/CON Tues Sept 7 50% Tuition Liability for full semester coursesAll Thurs Sept 9 Rosh Hashanah - No Classes COM and COGS; all others contact faculty if unable

to attend due to religious beliefsAll Fri Sept 10 E'Id al-Fitre - contact faculty if unable to attend due to religious beliefsCOGS/CHP/CON Mon Sept 13 70% Tuition Liability for full semester coursesAll Sat Sept 18 Yom Kippur - No Classes COM and COGS; all others contact faculty if unable to

attend due to religious beliefsCOGS/CHP/CON Mon Sept 20 100% Tuition Liability for full semester coursesAll Mon Oct 11 Columbus Day - No Classes - Clinics ClosedCHP/CON Tues Oct 12 Fall Break - No ClassesCHP/CON Fri Oct 15 Mid-Semester Grades DueCHP/CON Oct 18 - Nov 5 Spring Semester Open Enrollment-Matriculated StudentsCHP/CON Wed Nov 3 75% of the Semester Completed (WP/WF grades assigned)All Mon Nov 15 E'Id al-Adha - contact faculty if unable to attend due to religious beliefsAll Thurs Nov 25 THANKSGIVING Vacation Begins All Mon Nov 29 Classes ResumeCOGS Nov 29 - Dec 10 Spring Semester Open Enrollment-Matriculated StudentsCHP/CON Mon Dec 6 Last Day of ClassesCHP/CON Tues Dec 7 Study DayCHP/CON Dec 8 - 13 Final Exams (No exams on Sunday)CHP/CON Fri Dec 17 Student Evaluation Committee MeetingAll Fri Dec 17 Fall Semester Ends All Sun Jan 2 Degree Conferral for Fall Graduates - Revised

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1 All Mon Jan 3 SPRING SEMESTER BeginsCOGS/CHP/CON Mon Jan 3 Registration Begins - Non-Matriculated StudentsCOGS/CHP/CON Mon Jan 10 30% Tuition Liability for full semester coursesCOGS/CHP/CON Fri Jan 14 Last Day to Add or Drop courses without a late feeCHP/CON Fri Jan 14 Last Day to Drop a full semester course without a gradeAll Mon Jan 17 Martin Luther King Day - No Classes - Clinics ClosedCOGS/CHP/CON Tues Jan 18 50% Tuition Liability for full semester coursesCOGS/CHP/CON Mon Jan 24 70% Tuition Liability for full semester coursesCOGS/CHP/CON Mon Jan 31 100% Tuition Liability for full semester coursesCHP Sat Feb 19 Spring Vacation Begins Perfusion Sr StudentsCHP/CON Fri Feb 25 Mid-Semester Grades DueCHP/CON Sat Feb 26 Spring Vacation Begins 5pm (except 3rd year DPT & Perfusion Sr)CHP Mon Feb 28 Classes Resume Perfusion Sr StudentsCOM Sat Mar 5 Spring Vacation Begins MSI StudentsCHP/CON Mon Mar 7 Classes Resume (except 3rd year DPT & Perfusion Sr)CHP/CON Mar 7 - Mar 18 Summer Semester Open Enrollment - Matriculated StudentsCOM/COGS Sat Mar 12 Spring Vacation Begins MSII and Graduate Studies StudentsCOM Mon Mar 14 Classes Resume MSI studentsCOM Thur Mar 17 Match DayCHP/CON Fri Mar 18 Exit Assessment Exams

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COM/COGS Mon Mar 21 Classes Resume MSII and Graduate Studies StudentsCHP/CON Mar 21 - April 8 Fall Semester Open Enrollment - Matriculated StudentsCHP/CON Wed Mar 23 75% of the Semester Completed (WP/WF grades assigned) COM Mon Mar 28 Spring Vacation Begins MSIII and MSIV StudentsCOM Mon April 4 Classes Resume MSIII and MSIV StudentsCHP/CON Mon April 18 Last Day of Classes except DPT Year 3 & Med Scholars Year 1All Apr 19 - 26 Passover - contact faculty if unable to attend due to religious beliefsCHP/CON Tues April 19 Study DayCHP/CON Apr 20 - Apr 25 Final Exams (No exams on Sunday)All Fri April 22 Good Friday - contact faculty if unable to attend due to religious beliefs CHP/CON Wed April 27 Student Evaluation Committee MeetingCON/CHP/COM Fri April 29 Spring Semester Ends - MSIV, Nursing, & Health Professions (except DPT Year 3

& Med Scholars Year 1)COM Fri May 6 Spring Semeseter Ends MSIICOM Tues May 10 MSIV Grades CommitteeCOM Fri May 13 Dean's Appeals BoardCOM Tues May 17 MSII Grades CommitteeAll Sun May 22 COMMENCEMENT Ceremony All Sun May 22 Degree Conferral for Spring GraduatesCOM Wed May 25 Dean's Appeals BoardAll Mon May 30 Memorial Day - No Classes - Clinics ClosedCOM/COGS/CHP Fri June 3 Semester Ends MSI, Graduate Studies, DPT Year 3COM Tues June 7 MSI Grades CommitteeCOM Fri June 10 Dean's Appeals BoardAll Mon June 20 Alternate Degree Conferral for Spring GraduatesCOM/CHP Fri June 24 Spring Semester Ends MS III & Med Scholars Year 1COM Fri Aug 12 MSIII Grades CommitteeCOM Wed Aug 17 Dean's Appeals Board

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011 CHP/CON Mon May 2 SUMMER SEMESTER Begins (except as otherwise noted)

CHP/CON Mon May 2 Registration Begins - Non-Matriculated StudentsCHP/CON Fri May 6 Last Day to Add or Drop courses without a late feeCHP/CON Fri May 6 Last Day to Drop a full semester course without a gradeCHP/CON Mon May 9 30% Tuition Liability for full semester coursesCHP/CON Mon May 16 50% Tuition Liability for full semester coursesCHP/CON Mon May 23 70% Tuition Liability for full semester coursesAll Mon May 30 Memorial Day - No Classes - Clinics ClosedCHP/CON Tues May 31 100% Tuition Liability for full semester coursesCHP Mon June 13 Transitional DPT New Students Summer Semester Begins CHP Sat June 18 Perfusion, Med Tech, and Medical Biotech vacation beginsCHP Wed June 22 Last Day of Arts and Sciences Classes CHP Mon June 27 Perfusion, Med Tech, and Medical Biotech Classes ResumeCON Wed June 29 Last Day of Classes for Nursing All Mon July 4 Independence Day Observed - No Classes - Clinics ClosedCHP Wed July 6 Last Day of Classes Respiratory Care CHP Fri July 29 Last Day of Classes for Med Tech Jr CHP Fri Aug 5 Last Day of Classes for Rad Ther Jr, Med Imaging CHP Fri Aug 12 Last Day of Classes for Perfusion and Transitional DPTCHP Tues Aug 16 Student Evaluation Committee MeetingCHP/CON Tues Aug 16 Summer Semester EndsAll Tues Aug 30 Degree Conferral for Summer Graduates - Revised

10.16.2009College Codes COGS College of Graduate Studies

CHP College of Health ProfessionsCOM College of MedicineCON College of Nursing

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New York State Law - Section 224AStudents Unable Because of Religious Beliefs to Attend Classes on Certain Days

1 . No person shall be expelled or be refused admission as a student to an institution of higher education for the reason that he/she is unable, because of his/her religious beliefs, to attend classes or to participate in any examination, study or work equirements on a particular day or days .

2 . Any student in an institution of higher education who is unable, because of his/her religious beliefs, to attend classes on a particular day or days shall, because of such absence on the particular day or days, be excused from any examination or any study or work requirements .

3 . It shall be the responsibility of the faculty and of the administrative officials of each institution of higher education to make available to each student who is absent from school, because of religious beliefs, an equivalent opportunity to make up any examination, study, or work requirements which he may have missed because of such absence on any particular day or days . No fees of any kind shall be charged by the institution for making available to the said students such equivalent opportunity .

4 . If classes, examinations, study or work requirements are held on Friday after four o’clock post meridian or on Saturday, similar or makeup classes, examinations, study, or work requirements shall be made available on other days, where it is possible and practicable to do so . No special fees shall be charged to the student or these classes, examinations, study, or work requirements held on other days .

5 . If effectuating the provisions of this section, it shall be the duty of the faculty and of the administrative officials of each institution of higher education to exercise the fullest measure of good faith . No adverse or prejudicial effects shall result to any student because of his availing himself/herself of the provisions of this section .

6 . A copy of this section shall be published by each institution of higher education in the catalog of such institution containing the listing of available courses . It shall be the responsibility of the administrative officials of each institution of higher education to give written notice to students of their rights under this section, informing them that each student who is absent from school, because of his/her religious beliefs, must be given an equivalent opportunity to register for classes or make-up any examination, study or work requirements which he/she may have missed because of such absence on any particular day or days . No fees of any kind shall be charged by the institution for making available to such student such equivalent opportunity .

7 . As used in this section, the term “institution of higher education” shall mean schools under the control of the board of trustees of the State University of New York or the board of higher education of the city of New York or any community college .

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Registration InformationFALL SEMESTER, 2010Weiskotten Hall, Rm 3114NEW STUDENTS ONLY - Wednesday, August 18RETURNING STUDENTS - July 19 - July 30

Registration for returning students will take place in the Graduate Studies Office, Weiskotten Hall, Room 3114, July 19 - July 30 . Registration packets will be provided to the departments . Packets for incoming students will be available in Weiskotten Hall, room 3114 .Late Payment FeeA $50 late payment fee will be charged to all students if payment of tuition is not made by due date on mailed bill .In addition, a $40 fee will also be assessed if registration is not completed by July 30 .Student Health FormsAll required health forms of students enrolled in graduate programs must be completed and on file with the Student Health Service prior to registration .

Tuition Rates

State Residents . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . $3,940 .00/semester (12 credit hours or more) 328 .00/credit hour (11 credit hours or less)Out-of-State Residents . . . . . . . . . . . . . . . . . . . . . . . . . $6,625 .00/semester (12 credit hours or more) 552 .00/credit hour (11 credit hours or less)

Fees*College Fee (Required from all students) . . . . . . . . . . . . . . . $12 .50/semester (12 credit hours or more) 0 .85/credit hour (11 credit hours or less)Activity Fee (Paid fall and spring) . . . . . . . . . . . . . . . . . . . . $65 .00 (9 to 12 credit hours) 32 .50 (6 to 8 credit hours) 16 .25 (1 to 5 credit hours)Health Service Fee (Paid fall and spring) . . . . . . . . . . . . . . $91 .00/semester (12 credit hours or more) 7 .60/credit hour (11 credit hours or less)Disability Insurance Fee (Paid yearly) . . . . . . . . . . . . . $65 .00IMT Fee (Paid fall and spring) . . . . . . . . . . . . . . . . . . . . . $75 .00/semester (12 credit hours or more) 6 .25/credit hour (11 credit hours or less)

*Tuition rates are based on semester charges . These rates and fees are subject to change . The college and activities fees are non-refundable .

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SPRING SEMESTER, 2011Weiskotten Hall, Rm 3114November 29 - December 10

Registration will take place in the Graduate Studies Office, Weiskotten Hall, Room 3114, November 29 - December 10 . Registration packets will be provided to the departments . Packets for incoming students will be available in Weiskotten Hall, room 3114 .Late Payment FeeA $50 late payment fee will be charged to all students if payment of tuition is not made by due date on mailed bill .In addition, a $40 fee will also be assessed if registration is not properly completed by December 10 .Student Health FormsAll required health forms of students enrolled in graduate programs must be completed and on file with the Student Health Service prior to registration.

Tuition Rates

State Residents . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . $3,940 .00/semester (12 credit hours or more) 328 .00/credit hour (11 credit hours or less)Out-of-State Residents . . . . . . . . . . . . . . . . . . . . . . . . . . $6,625 .00/semester (12 credit hours or more) 552 .00/credit hour (11 credit hours or less)

Fees*College Fee (Required from all students) . . . . . . . . . . . . . . . $12 .50/semester (12 credit hours or more) 0 .85/credit hour (11 credit hours or less)Activity Fee (Paid fall and spring) . . . . . . . . . . . . . . . . . . . . . . $65 .00 (9 to 12 credit hours) 32 .50 (6 to 8 credit hours) 16 .25 (1 to 5 credit hours)Health Service Fee (Paid fall and spring) . . . . . . . . . . . . . . . 91 .00/semester (12 credit hours or more) 7 .60/credit hour (11 credit hours or less)Disability Insurance Fee (Paid yearly) . . . . . . . . . . . . . . . $65 .00IMT Fee (Paid fall and spring) . . . . . . . . . . . . . . . . . . . . . . . . $75 .00/semester (12 credit hours or more) 6 .25/credit hour (11 credit hours or less)

*Tuition rates are based on semester charges . These rates and fees are subject to change . The college and activities fees are non-refundable .

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Registration InstructionsSUNY Graduate StudentsThe enclosed (multi-part) course registration form should be completed by you and signed by your advisor . Indicate number(s) and title(s) of course(s), where taken (SUNY, SU, COES&F) . Graduate students who intend to register for classes at SU and/or the COES&F are also required to register there . Special registration packets and course schedules for these schools are available in the Graduate Studies Office, Weiskotten Hall, Room 3114 .The New York State Tuition Waiver application (enclosed only if you are eligible) is to be completed by you, signed by your department chairman, and submitted to the Office of Graduate Studies, NO LATER THAN THE DATE OF REGISTRATION . Waivers will not be accepted after that date unless approved by the College of Graduate Studies .ALL NEW YORK STATE RESIDENTS MUST COMPLETE A NEW YORK STATE TUITION ASSISTANCE PROGRAM (TAP) APPLICATION . Add/Drop actions for SUNY Upstate Medical University must be channeled through the SUNY Upstate Medical University at Syracuse, Office of Graduate Studies . [Please note add/drop dates on academic calendar in front of book]ID CardsID cards are issued or validated in the PAYROLL OFFICE located in Jacobsen Hall, Room 100, on the day of registration . A TUITION RECEIPT is required .Car Registration and ParkingCar registration and the issuance of parking permits is completed at the Parking Office which is located in the University Hospital, Room 1801 . Car registration and ID cards will be required for verification . The Parking Office is open Monday through Friday, from 7AM to 4PM .Student HealthThe college has a student health service which is located on the fourth floor of Jacobson Hall . A description of the services available through Student Health is in the Student Handbook which can be obtained from the Office of Graduate Studies, or the Office of Student Affairs, Campus Activities Building, Room 202 .Health InsuranceHealth Insurance coverage is mandatory for all students . Information describing a student health insurance plan is available in the Office of Graduate Studies, or the Office of Student Affairs in the Campus Activities Building, Room 202 . Veteran’s Educational BenefitsStudents eligible for VA benefits should contact Ms . Jennifer Martin-Tse, Registrar, SUNY Upstate Medical University at Syracuse, 155 Elizabeth Blackwell Street, Room 203, Syracuse, NY 13210 (315/464-4604) .Special Students (Non-matriculated)To be eligible for registration in a graduate course as a “special” or “non-matriculated” student, the student should be employed at the Upstate Medical University or be a student in one of the Center’s academic programs (approval of program director or supervisor is required) or obtain special student category upon formal application to the Dean of the College of Graduate Studies by the chairman of a degree granting program . Registration forms for “special” students may be obtained from the Office of Graduate Studies, Weiskotten Hall, Room 3114, 766 Irving Avenue, Syracuse, NY 13210 .

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Agreement between United University Professions and the State of New York 1982-85: Article 36 1 Program for Tuition AssistanceThe State agrees to continue the existing Tuition Assistance Program using a “space available” concept . When space is available, employees may enroll in a course on a tuition free basis, subject to the following requirements:

1 . The University determines when space is available, recognizing that such determination must be made in sufficient time to permit enrollment by employees .

2 . Employees must meet course prerequisites .3 . All fees other than tuition shall be paid by employees .4 . Employees may enroll in a MAXIMUM of one course per semester in special session, for example,

summer session and intersession .5 . Minimum enrollment requirements established by the university as a necessary condition for

offering a course shall not be affected by students interested in enrolling in a course on a space available basis .

6 . The program shall continue for the term of the agreement .Syracuse University (SU) and COES&F StudentsRegistration for courses at SUNY Upstate Medical University at Syracuse, College of Graduate Studies, is restricted to graduate students . Permission is required of your home college advisor(s) and the course instructor(s) of the College of Graduate Studies, SUNY Upstate Medical University .Prior to registering at your home college, appropriate SUNY registration forms need to be completed . They are available at the Office of Graduate Studies, 766 Irving Avenue, Room 3114, Syracuse, NY 13210 . Instructions concerning payment of tuition for SUNY Upstate Medical University courses are listed in the Syracuse University Registration Booklet .ADD/DROP actions for Syracuse University must be channeled through the SUNY Office of Graduate Studies .Family Educational Rights and Privacy Act The Family Educational Rights and Privacy Act of 1974 requires us to make provisions for complying with Section 99 .5, “Directory Information .” Directory information is defined as information which may be released to the public . If a student wishes to restrict the release of directory information, s/he should indicate any restrictions at the time of registration . Directory information includes all of the following:

Name Address Telephone Number Date/Place of Birth Program of Study Dates of Attendance Degrees/Awards Received from the most recent previous educational agency or institution

attendedThe enclosed registration form (computer data sheet) complies with the above Family Educational Rights and Privacy Act . Please present your registration form along with the (multi-part) course registration form and biographical data sheet (incoming or special, non-matriculated students only) when you come to the Registration Desk .

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CORECURRICULUM

Core CurriculumPh D CandidatesWith the exception of the students enrolled in the M .D ./Ph .D .program, all PhD students are required to take the following “core” courses:

First YearFall

GS604 Graduate Student Research Opportunities – 0 crGS612 Biomedical Sciences Laboratory Rotations (1st Rotation) – 2 crGS616 Foundations of Molecular and Cellular Biology – 4 crGS617 Introduction to Applied Biostatistics and Research Design – 2 crGS618 Responsible Conduct of Scientific Research (Research Ethics) I – 1 cr

SpringGS612 Biomedical Sciences Laboratory Rotations (2nd Rotation) – 2 crGS612-1 Biomedical Sciences Laboratory Rotations (3rd Rotation) – 2 crGS892 Introduction to the Presentation and Analysis of Scientific Literature: Journal Club – 1 cr

Second YearFall

GS619 Responsible Conduct of Scientific Research (Research Ethics) II – 1 crIn addition, students must take additional advanced electives .

M S CandidatesMS students are required to take:

First YearFall

GS618 Responsible Conduct of Scientific Research (Research Ethics) I – 1 cr

Second Year

FallGS619 Responsible Conduct of Scientific Research (Research Ethics) II – 1 cr

Additional courses determined by degree granting program and Advisor .

MD/PhD CandidatesMD/PhD students are required to take in the Fall semester of the first year in PhD portion of the MD/PhD Program:

GS618 Responsible Conduct of Scientific Research (Research Ethics) I – 1 crGS619 Responsible Conduct of Scientific Research (Research Ethics) II – 1 cr

Additional courses determined by MD/PhD Program, degree granting program and Advisor .

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FOUNDATIONS OF MOLECULAR AND CELLULAR BIOLOGY GS6164 Credit Hours

Coordinators (Course directors) Dr . Stephan Wilkens Dr . Christopher Turner Dr . David Mitchell Dr . Jennifer Moffat

Period Offered: FallCourse Philosophy and Goals: This course seeks to bring a collection of incoming students with diverse interests and backgrounds up to a basic level of understanding of biomedical sciences in preparation for joining a research lab at SUNY Upstate . Lecture material is presented so as to engage students in the methods and experiments that have led to our current understanding of cell function, in particular by using real examples from the primary literature coupled with a problem-based approach . The course is sufficiently demanding so as to promote those students who have the level of commitment required to succeed in the graduate program .Course Description: This course provides a comprehensive background for students in the Biomedical Sciences Program . It covers fundamental and advanced topics in biochemistry, molecular biology, and cell biology . Lectures and discussions are based on primary research articles, reference books, and lecture notes . Major divisions of the course are 1) properties of biomolecules, 2) cell organization and regulation, and 3) cell function . Location: Room 3113 Weiskotten Hall

INTRODUCTION TO APPLIED BIOSTATISTICS AND RESEARCH DESIGN GS6172 Credit Hours

Course Coordinator(s): Drs . Donald Cibula and Frank MiddletonPeriod Offered: FallCourse Description: This course introduces the basic principles of biostatistics and experiment design for research in the biomedical sciences . Emphasis will be placed on application of biostatistical methods and interpretation of the outputs of statistical software . A concept-focused approach will be used to teach the statistical content, which includes descriptive statistics, probability distributions, point and interval estimation of population parameters, and hypothesis testing . A variety of one and two-sample parametric and non-parametric tests for continuous and categorical data are covered, as are one and two-factor ANOVA, tests for bivariate frequency data, and simple linear regression . The second portion of the course will require that stu-dents apply and reinforce their new-found knowledge to critically assess experiment designs and statistical methods used in examples from the scientific literature .Location: Room 4507 Setnor

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RESPONSIBLE CONDUCT OF SCIENTIFIC RESEARCH (RESEARCH ETHICS) I GS6181 credit

Course Coordinator: Amy Campbell, JD, MBEPeriod Offered: Fall SemesterCourse description: Biomedical scientific research is a complex undertaking, with a theoretical framework for how scientific progress should be made, professional norms about acceptable scientific conduct, and an ever-expanding array of ethical challenges following on the heels of technical advances . The complexity and rapid advance of biomedical research, as well as numerous instances of deception, conflicts of interest, and inappropriate care of animals or humans involved in research, suggest that merely having good intentions is not always sufficient . This course will cover core infor-mation in the responsible conduct of scientific research for early-stage graduate students in order to:

• improve their moral reasoning skills in the context of scientific research;

• deepen their understanding of the professional norms of science; and

• gain an understanding of the regulatory framework and ethical principles governing biomedical research .

Course topics include an introduction to scientific and moral reasoning, the regulatory framework governing science, and discussions of the pressures of science, authorship, plagiarism, peer review, collaborative re-search, mentoring, and data ownership/management and intellectual property .Textbook(s):Macrina FL, Scientific Integrity: An Introductory Text with Cases (3rd edition), 2005: Washington DC: AMS Press .Dates: Tues ., 10:00 AM - 12:00 Noon, Room 3509/3510 Setnor, first 7 weeks of the Fall Semester

RESPONSIBLE CONDUCT OF SCIENTIFIC RESEARCH (RESEARCH ETHICS) II GS6191 credit

Course Coordinator: Amy Campbell, JD, MBEPeriod Offered: Fall SemesterPrerequisite: GS618 Responsible Conduct of Scientific Research (Research Ethics) ICourse Description: This course builds on GS618 Re-sponsible Conduct of Scientific Research (Research Eth-ics) I, briefly revisiting core topics in the responsible con-duct of scientific research, and then covering additional topics, including: conflicts of interest, the regulatory frameworks governing the use of humans and animals in research (including an international perspective), and ethical issues in genetics and stem cell research .Unlike the lecture-based format of Research Ethics I, given the students’ additional experience and lab as-signments, this course will utilize a case-based format, short didactic presentations, and in-class exercises, endeavors to help graduate students:

• hone their moral reasoning skills in the context of scientific research; and

• apply their understanding of the professional norms of science to cases .

Textbook(s): Macrina FL, Scientific Integrity: An Introductory Text with Cases (3rd edition), 2005: Washington DC: AMS Press .Dates: Tues, 10:00 AM - 12:00 Noon, Room 3509/3510 Setnor, Weeks 8-14 of the Fall Semester

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INTRODUCTION TO THE PRESENTATION AND ANALYSIS OF SCIENTIFIC LITERATURE: JOURNAL CLUB GS8921 Credit HourCoordinator(s): Dr . Patricia Kane, Course Director

and Biomedical Sciences FacultyPrerequisite(s): NonePeriod Offered: Fall/SpringRequired for all entering graduate students .Course Description: This course gives students the opportunity to read, critically evaluate, and present research articles in a variety of fields . During this course students are expected to develop a high standard of scientific analysis and good public pre-sentation skills . Students will be required to present one to two paper(s) each semester depending on time availability and to actively participate in class discussions when not presenting . This course is required for all first year graduate students in the spring semester, but, if space is available, it is also offered as an elective for advanced students .Students will be assigned to one of three sections at the first class (part A, B or C) . We encourage students to begin selecting papers for their presentation be-fore the first class . Textbook(s): NoneLocation: Room 3113 Weiskotten Hall

GRADUATE STUDENT RESEARCH OPPORTUNITIES GS6040 Credit Hours

Instructor(s): Members of the Graduate Faculty Organization representing the six Ph .D . training programs .Coordinator(s): Dr . Steven GoodmanPrerequisite(s): Non-Matriculated students must have prior permission from the lab mentor and the Dean of the College of Graduate Studies .Period Offered: FallCourse required for all first-year graduate studentsCourse Description: With one full afternoon per program, each of the six Ph .D . training programs will describe its currently active research projects . This description will be presented in a format which the program’s faculty feels best displays all its research activities . Two major goals of these presentations are to: 1) acquaint the incoming graduate students with the breadth of research being pursued within each graduate program, and 2) to thereby give the incoming graduate students further information upon which to base their own choice of research area for their dissertations .Textbook(s): None

BIOMEDICAL SCIENCES LABORATORY ROTATIONS GS6122 Credit Hours/rotationCoordinator(s): Graduate FacultyPrerequisite(s): Non-Matriculated students must have

prior permission from the lab mentor and the Dean of the College of Graduate Studies .

Period Offered: Fall/Spring/Summer semestersThis is a special research training program designed to acquaint students with areas of research and/or the use of methods, techniques, and instrumentation . Course Description: Three different research labora-tory rotations taken consecutively are required for all first-year PhD students . Rotations begin approximate-ly September 30, January 3, and March 21 (in three different research laboratories) . An optional fourth rotation in the summer may be taken . Written report due to Advisor at the end of each rotation [Students may petition Advisory Committee to be exempt from the 3rd rotation, under very special circumstances] .Textbook(s): None

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Biochemistry And Molecular Biology

BIOCHEMISTRY & MOLECULAR BIOLOGY LABORATORY ROTATIONS B6092 Credit Hours

Coordinator(s): Dr . David Amberg and Biochemistry FacultyPrerequisite(s): NonePeriod Offered: Fall/Spring See Course Instructor for dates, time and location .Course Description: This laboratory course is primarily intended for Biochemistry graduate students . The course will provide instruction in laboratory techniques commonly used in biochemical and molecular biological laboratories and will aid students in the selection of a research advisor . This course is offered year round . Research areas covered include: oxidative phosphorylation, enzymology, protein chemistry, regulation of growth and differentiation, DNA replication, protein structure and folding, actin cytoskeleton, RNA processing and cell polarity, organelle acidification and transcriptional regulation, x-ray defraction and protein structural determination .Textbook(s): None

METHODS OF BIOCHEMISTRY AND MOLECULAR BIOLOGY RESEARCH B617Variable Credit

Coordinator(s): Dr . David Amberg and Biochemistry FacultyPrerequisite(s): 612GS Biomedical Sciences Laboratory Rotations or permission of InstructorPeriod Offered: Year Round, by ArrangementCourse Description: Methods of research used by the faculty are demonstrated . Problem design and research methods are emphasized .Course deals with individualized laboratory experience . Topics agreed upon by student and faculty sponsor . Often taken between rotations and Thesis research to fulfill credit requirements .

BIOCHEMISTRY SEMINAR B6200 Credit Hours

Coordinator(s): Dr . D . AmbergPrerequisite(s): NonePeriod Offered: Fall/SpringCourse Description: Presentations of recent research activities by invited speakers . Mon ., Rm . 2231, WH 12:00 PM - 1:00 PMTextbook(s): None

INDEPENDENT STUDIES IN BIOCHEMISTRY AND MOLECULAR BIOLOGY B6381 – 3 Variable Credit

Coordinator(s): Dr . Barry Knox and Biochemistry staffPrerequisite(s): General Biochemistry or equivalentPeriod Offered: Fall/Spring See Course Instructor for dates, time and location .Course Description: A tutorial course designed for graduate students in biochemistry, or related dis-ciplines, that will involve in-depth review of recent developments in biochemical research . May include 1) literature searches, 2) seminar and/or lectures, 3) hands on experience with new techniques available in the department, and 4) a written report .The purpose of the course is to develop a broad knowledge of the biochemical literature as the student advances in his/her more defined research goals .Textbook(s): None

POST CORE CURRICULUM

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GENE EXPRESSION AND EPIGENETIC REGULATION B6473 Credit Hours

Coordinator(s): Dr . Barry KnoxInstructor(s): Dr . Barry Knox & Dr . Robert WestPeriod Offered: SpringCourse Description: Directed reading and student directed presentations on the primary literature that relates to gene expression from transcription to nuclear export . Maximum 12 students

RESEARCH DESIGN IN BIOCHEMISTRY & MOLECULAR BIOLOGY B648 3 credits

Prerequisite: General biochemistry and molecular biology or equivalent and permission of InstructorCoordinator(s): Dr . Barry Knox and Biochemistry & Molecular Biology staffPeriod Offered: Fall/Spring Dates, times and location to be arranged by instructorCourse Description: This course promotes the development of critical thinking and writing important to the students’ future career as scientists . The student will gain experience in designing an original dissertation research project and preparing the plan in a formal hypothesis-based research proposal . Students will learn the essential features of scientific writing, with the emphasis on developing skills necessary for effectively communicating their research design . In the first part of the course the essentials of clear, unambiguous scientific writing will be highlighted through examples and written exercises . The elements of good and bad scientific writing will be discussed and compared in a class setting . In the second part of the course, the important features of research design will be covered, implemented in the writing of a research grant-style proposal . The research proposal will be in the student’s area of interest, with help from the Instructor and experts in the field . Students will publically present their final proposal in an overview seminar to be arranged at the end of the course . Scheduling: The first month of the course will initially consist of four 90-minute sessions of the entire class . Subsequent meetings will be on an individual basis (by arrangement) for approximately 1 hour every 2 weeks .

Course objectives:(1) develop a cogent, hypothesis-based research proposal that constitutes a “first draft” for their thesis work as well as a proposal to be submitted for extramural funding .(2) give a clear, compelling oral presentation of the proposal and defend it .Grading: The course will use a satisfactory/unsatisfactory grading format . Grades will be based on effort and improvement on the exercises and assignments .

TOPICS IN QUANTITATIVE BIOLOGY B649 1 credit (2 hr sessions/every other week)

Coordinator(s): Dr . Barry Knox & Dr . Peter CalvertPeriod Offered: FallCourse grading: Satisfactory / UnsatisfactoryPart 1 Quantitative Biochemistry (Thermodynamics, physical biochemistry, enzyme kinetics, water) .Part 2 Quantitative Cell Biology (Bioimaging, protein-protein interactions in living cells, diffusion) .Part 3 Design Principles of Biological Circuits (Network basics, autoregulation, feed-forward loops, robustness, kinetics) .This course is a seminar course on how, at a systems level, biological molecules interact and cells respond to their environment using quantitative approaches and analysis . Cross disciplinary techniques will be emphasized, to encourage students to think about traditional subjects in new ways . The focus will be on the description and use of models to explain how molecules drive complex phenomenon essential to cellular functions . The class will include lecture, presentation of original research articles and a final paper .

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SCIENTIFIC WRITING IN BIOCHEMISTRY B6501 Credit Hour

Coordinator(s): Dr . Stewart Loh and Biochemistry and Molecular Biology FacultyPrerequisites: First year core curriculumPeriod Offered: Fall-springCourse Description: This course is required in the second year for all students performing their thesis research in the Department of Biochemistry and Molecular Biology . The purpose of this course is to provide practice and one-on-one instruction in scientific writing . Each week the student will be assigned a paper to read from the primary literature by one of the program members, usually in the faculty member’s area of expertise . The student will have one week to read the paper and write a concise one page summary and critique of the paper . In the second week, the student will revise the paper, with the direct guidance and final approval of that faculty member . This process will continue until each student has completed a writing assignment from each member of the Biochemistry and Molecular Biology Graduate Program .Grading: Satisfactory / Unsatisfactory

PROTEIN SORTING AND VESICULAR TRAFFICKING B6641 Credit Hour

Coordinator(s): Dr . Patricia KanePeriod Offered: Spring, Even YearsCourse Description: The current literature will be used to investigate current controversies and discoveries in protein sorting and trafficking .

BIOENERGETICS OF ENERGY TRANSDUCING MEMBRANES B6652 Credit Hours

Coordinator(s): Dr . Richard CrossPeriod Offered: Spring, Even YearsCourse Description: Using both lecture and student driven discussions the latest research on the capture of light energy, the electron transport chain and oxidative phosphorylation will be investigated .

PROTEIN STRUCTURE DETERMINATION B6662 Credit Hours

Coordinator(s): Dr . Stephan WilkensInstructor(s): Drs . Stewart Loh, Edward Berry and Stephan WilkensPeriod Offered: SpringCourse Description: The primary literature will be used to cover advanced topics in protein structure determination and protein folding . This may include such topics as protein structure determination by X-ray crystallography, nuclear magnetic resonance spectroscopy and cryo electron microscopy, protein structure prediction by computational methods, pathways of protein folding and prion proteins

RESEARCH IN BIOCHEMISTRY B700Variable Credit

Coordinator(s): Dr . R . L . Cross and Biochemistry & Molecular Biology FacultyPrerequisite(s): NonePeriod Offered: Fall/Spring See Advisor .Course Description: Original thesis research in the field of Biochemistry under the supervision of a member of the staff .Textbook(s): None

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SB3

BIOLOGICAL AND MEDICAL PHYSICS (SU: PHY 615) B6113 Credit Hours

Coordinator(s): Dr . Stewart LohInstructor(s): Liviu Movileanu; Office: 211 (SU Physics Bldg .) E-mail: lmovilea@physics .syr .edu; Phone: (315) 443-8078Prerequisite(s): SB3 student or approval of course coordinator .Period offered: Fall semesterCourse description: Biological and Medical Physics (PHY 615, 3 credits) is a one-semester graduate level course intended for students from physical, chemical andbiomedical sciences . The PhD students enrolled in Structural Biology, Biochemistry and Biophysics Program (SB3), or those from Biotechnology and Bio-medical Sciences Programs (SUNY-ESF, SU and Upstate Medical School) are very welcome . From the very beginning, I have to mention that this is not a course to teach either “biology for physicists” or “physics for biologists and physicians” . The emphasis will be on a selected range of “hot topics” that lie at the interface between physical, chemical and biomedical sciences . The primary aim is to have an overview of the fun-damental biophysical research questions, as well as recent experimental developments and techniques that engage a multidisciplinary effort . In addition, we will discuss “applicative topics” of biological physics in several realms, including nanobiotechnology, biosen-sors, drug delivery, and medical imaging . Therefore, much of the content of PHY 615 will not be presented in a traditional manner . Finally, from a practical point of view, the Biological and Medical Physics course will establish strategies for people with complementary backgrounds who will be having the chance to work in multidisciplinary areas .

BIOCHEMISTRY I B6183 Credit Hours

Coordinator(s): Dr . Stewart LohInstructor(s): Welch/CosgrovePrerequisite(s): SB3 student or approval of course coordinator .Period Offered: Fall

Course Description: Introduction to basic biochemical principles, from amino acids and their properties, to the principles of protein structure and function . The genetic code and mechanisms of DNA replication, RNA transcription and translation will be explored with a focus on DNA/RNA structure, proteins and enzyme mechanisms .Course goals: To develop a general understanding of core biochemical concepts, including the structures and functions of two classes of biological macromolecules, proteins and nucleic acids . An appreciation of the experimental approaches used to develop the biochemical core concepts will also be developed . Grades: Four equally weighted exams per semester; your grade will be determined by your top three scores, BUT YOU MUST TAKE ALL 4 EXAMS There will be no curve . The 4th exam will be given during the regularly scheduled time for the final but will NOT be a comprehensive exam . NO MAKE-UP EXAMS WILL BE GIVEN Schedule: M, W, F 9:30-10:25 001 Life Sciences Complex, SUTextbook(s): Biochemistry, 5th edition (2002), by Berg, Tymoczko and Stryer .

MOLECULAR BIOLOGY TECHNIQUES B6193 Credit Hours

Coordinator(s): Dr . Stewart LohInstructor(s): Dr . KretzerPrerequisite(s): SB3 student or approval of course coordinator .Period offered: FallCourse description: One hour of lecture and six hours of laboratory . Techniques used in molecular biology research are presented, focusing on DNA but including some coverage of RNA and proteins . Included are the extraction, measurement and analysis of nuclear and organellar DNAs from a variety of organisms . Students are required to complete a laboratory project or library research paper . Schedule: Illick 425, ESF

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BIOCHEMICAL METHODS FOR STRUCTURAL BIOPHYSICS B6263 Credit Hours

Coordinator(s): Dr . Stewart LohInstructor(s): Dr . BraimanPrerequisite(s): SB3 student or approval of course coordinator .Period offered: Spring semesterCourse description: Modern experimental methods for studying structures and functions of biological macromolecules . Lab experiments in preparation of macromolecules samples and biophysical measurements with visits to specialized labs . Additional work required of graduate students .Schedule: Bowne Hall 403, SU

MOLECULAR SPECTROSCOPY AND STRUCTURE (SU: CHE 546) B6373 Credit Hours

Coordinator(s): Dr . Stewart LohInstructor(s): HudsonPrerequisite(s): SB3 student or approval of course coordinator .Period Offered: Every SemesterCourse Description: For the nonspecialist . Three topics each semester, chosen from the following list of topics: atomic spectroscopy and angular momentum, laser chemictry and spectroscopy, symmetry and griup theory, nuclear magnetic and resonance spectroscopy, vibrational spectroscopy, laser applications of molecular spectroscopy .

MOLECULAR BASIS OF EVOLUTION B6393 Credit Hours

Coordinator(s): Dr . Stewart LohInstructor(s): Dr . KretzerPrerequisite(s): SB3 student or approval of course coordinator .Period offered: Spring semesterCourse description: Two hours of lecture and one hour of discussion . The major processes of organic evolution (e .g ., such as mutation, natural selection, speciation and extinction) are discussed in a molecular-level context . Coverage ranges from changes to genic and nongenic regions of

the genome to the evolution of entire genomes . Methods used to study molecular evolution and to reconstruct phylogenies are described and demonstrated . Students will organize and lead class discussionsSchedule: ESF

PLANT BIOTECHNOLOGY B6403 Credit Hours

Coordinator(s): Dr . Stewart LohInstructor(s): Dr . KretzerPrerequisite(s): SB3 student or approval of course coordinator .Period offered: Spring semesterCourse description: Lectures, discussions, student presentations, and a laboratory project to develop understanding of cloning, gene modification, and the transformation of plant species with emphasis on woody plants . Uses of transgenic plants as food, fiber and oil crops, as biological factories for other products, and in phytoremediation of pollutants will be discussed .

INTRODUCTION TO SB3 RESEARCH B6522 Credit Hours

Coordinator(s): Dr . Stewart LohInstructor(s): Dr . Stewart Loh and SB3 FacultyPrerequisite(s): SB3 student or approval of course coordinator .Period Offered: Fall/SpringCourse Description: Students will complete three sequential offerings of this course, one in the second half ot he Fall semester following “Introduction to SB3 Faculty,” and two in the Spring semester . Students will conduct research supervised by an SB3 faculty member for an 8-week period . This course will provide the students with instruction in the use of the modern instruments and methodology . The advisor will provide a reading list and exam to the student orally at the end of the rotation . A written evaluation and list of mastered techniques will be placed in the student’s file and this will be referred to in developing breadth questions for the oral qualifying exam . A second purpose of the course is to help the student make a well-informed choice of thesis advisor .

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MOLECULAR MODELING (SU: BCM684) B6543 Credit Hours

Coordinator(s): Dr . Stewart LohInstructor(s): Dr . Tom Duncan (UMU), Dr . Phil Borer (SU),Prerequisite(s): SB3 student or approval of course coordinator .Period Offered: Spring semester Course Description: Enrollment: Limited to 15 students . Students will become proficient in molecular modeling by attending lectures and completing projects using available work stations . Topics covered include the following:

1 . Unix survival skills2 . Download and modify protein data bank files3 . Visualization and rendering4 . Strategies for minimization and dynamics5 . Energy and simulation temperature6 . Kinetic analysis of a two-state jump7 . Dynamics of an inhibitor bound to HIV- I

protease8 . Simulating statistical behavior of the alpha

helix-coil transition9 . Introduction to protein homology modeling

10 . Protein sequence analysis and alignment11 . Classification and recognition of protein folding

motifs12 . Approaches to three-dimensional modeling of

proteins13 . Evaluation and refinement of three-dimensional

models

SB3 JOURNAL CLUB (SU: BCM630) B6551 Credit Hour

Coordinator(s): Dr . Stewart LohInstructor(s): Drs . Loh and BorerPrerequisite(s): SB3 student or approval of course coordinator .Period offered: Fall/SpringCourse description: Students will select and present recent articles drawn from structural biology, biochemistry and biophysics journals . SB3 faculty will facilitate discussion and critique student performance .

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Cell and Developmental Biology

HUMAN ANATOMY A5059 Credit Hours

Instructor(s): Dr . N . B . Berg, Dr . S . Stearns and staffPrerequisite(s): Matriculation in the College of Medicine and/or Graduate Studies or approval of course directorPeriod Offered: Fall/SummerCourse Description: The study of the anatomical organization of the human body is learned primarily through dissection and supplemented with lectures . This format enables the student to appreciate the range of structural variation from normal to pathologic and the role development plays in this process . The anatomical basis of disease is stressed through small group interactions, case studies and computer assisted instruction . This course also provides the student with a firm background in imaging anatomy and introduces the student to imaging as a diagnostic tool . Days and Times: TBA Weiskotten Hall Addition 9295 (Lecture), Weiskotten Hall 143 (Lab) Summer Semester - June - August Mon . - Fri ., 9:00 AM - 2:00 PM DailyTextbook(s):Essential Clinical Anatomy - 2nd Edition, Keith Moore, MD , PhD & Ann Agur . Lippencott Williams and Wilkens - PublisherLangman’s Medical Embryology - 8th Edition, TW Sandler, Lippencott Williams and Wilkens - PublisherNetter’s Atlas of Human Anatomy - 2nd Edition, Arthur Dalley, PhD, Novartis - Publisher(to be provided by the Upstate Medical University Alumni Foundation)Recommended Material:Atlas: Grant’s Atlas of Anatomy - 9th Edition, Ann Agur, Lippencott Williams and Wilkens - Publisher

INTRODUCTION TO NEUROSCIENCE (SAME AS N507) A5073 Credit Hours

Coordinator(s): Dr . Russell Durkovic, Director Dr . Dennis Stelzner, Co-DirectorPrerequisite(s): Approval of course directorPeriod Offered: Spring or SummerCourse Description: The Systems Neuroscience course will consist of components of the Brain and Behavior course given to first year medical students .These components will include the study of systems of neuroscience, including sensory, motor, limbic systems, sleep and awakening, and basic cognitive processing . A total of 29 lectures with 2 essay examinations . The summer session will be a combination of video presentations and live tutorials .

MICROSCOPIC ANATOMY A5174 Credit Hours

Instructor(s): Dr . T . J . Poole and StaffPrerequisite(s): NonePeriod Offered: SpringCourse Description: Development, structure, and functions of the primary tissues and organ systems . The various organ systems are analyzed for structural arrangements; correlation of form and function is emphasized at both the light microscope and ultrastructural levels . Lecture, laboratory, and conference . Lecture - Weiskotten Hall Addition, Rm . 9295 Labs - Weiskotten Hall Addition, 7th FloorTextbook(s): Upstate Medical University Microscopic Anatomy Syllabus

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GRADUATE CELLULAR ANATOMY A6132 credits

Course Coordinator: Dr . Scott BlystoneCourse Instructors: Drs . Scott Blystone, Ira Ames, David PruynePeriod Offered: Fall SemesterPrerequisite: College of Graduate Studies’ Core CurriculumClass Size: Limited to 12 students .Course Description: Graduate Cellular Anatomy will provide an opportunity for graduate students to independently visualize cells, tissues, and organs of the human body by direct light-microscopic observation of prepared histologic specimens and develop their teaching and presentation skills . Course instructors will give introductory lectures on the histology of the basic tissue types . Each lecture will be followed by a guided laboratory session where each student will use their own university microscope to explore these tissue types . Course participants will select organ systems of interest and prepare presentations on the histology of those organ systems and present it to the class . Digital images taken from the class slide sets will be provided to enhance student presentations . Student presentations will also be followed by a laboratory session for students to explore that organ system . Students will use advance reading of a textbook and instructor guidance to aid in visualization of histologic specimens of the organ system of the day . Grading will be based on class participation, presentation, and a short paper detailing aspects of cellular anatomy important to the student’s thesis research .Textbook:A combined text and color atlas of histology will be required . Suitable examples include those by Junquiera, Ross, Wheater, or Kerr, available at the bookstore and on reserve in the library . A limited number of copies will be available for loan from the course instructors .Dates: Mon . 1:00-3:00pmLocation: 7th Floor, WH, Lab #5

CONTEMPORARY CELLULAR, MOLECULAR AND DEVELOPMENTAL BIOLOGY A6143 Credit Hours

Instructor(s): Dr . T . Poole and staffPrerequisite(s): Permission of instructor Minimum of four students requiredPeriod Offered: FallCourse Description: Lectures, student presentations, and discussions dealing with cellular and molecular mechanisms during embryonic development . Classical as well as contemporary concepts will be emphasized . Textbook(s): None

SPECIAL TOPICS IN ANATOMICAL SCIENCES A615Variable Credit

Coordinator(s): Dr . J . W . Sanger and the Cell & Developmental Biology StaffPrerequisite(s): Approval of the departmentPeriod Offered: This course is offered by arrrangement only

(615A - Non-teaching course number, fall-spring)(615A1 - Teaching in Developmental and Human

Anatomy, Variable Credit, fall, Dr . N . B . Berg and Staff)

(615A2 - Teaching in Neuroscience, 3 credits, spring, D . Stelzner and Staff)

(615A3 - Teaching in Histology, 3 credits, spring, Dr . T Poole and Staff)

Course Description: Advanced work in any subdiscipline of anatomical sciences such as developmental biology, cellular biology and fine structure, gross anatomy, and neurosciences .This course is offered by arrangement, year round .Textbook(s): None

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METHODS OF CELL & DEVELOPMENTAL RESEARCH A617Variable Credit (Maximum of 12 Credit Hours)

Coordinator(s): Dr . J .W . Sanger & Cell & Developmental Biology StaffPrerequisite(s): Approval of the departmentPeriod Offered: This course is offered year round by arrrangement Course Description: Methods of research used by the faculty are demonstrated . Problem design and research methods emphasized .Textbook(s): None

NEUROANATOMY LAB (SAME AS N621) A6212 Credit Hours

Coordinator(s): Dr . Dennis Stelzner Period Offered: SpringCourse Description: This course will provide students the opportunity to dissect the human brain and gain an appreciation for three-dimensional organization in the central nervous system .Textbook(s): None .

RESEARCH IN CELL & DEVELOPMENTAL BIOLOGY A700 1Variable Credit

Coordinator(s): Dr . J .W . Sanger & Cell & Developmental Biology StaffPrerequisite(s): NonePeriod Offered: This course is offered year round by arrrangement Course Description: Original dissertation research in anatomical sciences under supervision of a staff member .Textbook(s): None

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Microbiology and ImmunologyMEDICAL MICROBIOLOGY M510 7 Credit Hours*

Coordinator(s): Dr . P . Granato, and the Microbiology and Immunology facultyPrerequisite(s): Permission of department chairmanPeriod Offered: FallCourse Description: Lectures and laboratories in general and medical virology, bacteriology, entomology, parasitology, and mycology .Textbook(s): Microbiology, to be announced

PROBLEMS IN CELLULAR AND MOLECULAR IMMUNOLOGY M610 3 Credit Hours

Coordinator(s): Dr . Allen Silverstone and Microbiology FacultyPrerequisite(s): At least one course in Microbiology, Immunology, and Cell and Molecular Biology, or by permission of instructor .Period Offered: FallCourse Description: This course will be run in a tutorial/seminar format with three 1 .5 hour sessions per topic with a total of 10 topics . The first session will be an overview of the topic . The second session will be a discussion of 2-4 papers in the topic area . The third session will discuss student answers to research problems in the topic area . Topics could include: Mechanisms of Generation of Variability; Recognition by the T-Cell Receptor; Regulation of Immune Recognition in the Nervous System; Lymphocyte Activation Cascades; Immunotherapy for Cancer; Viral Immunomodulation; Immunological Memory; Cytokines in Rheumatoid Arthritis .Textbook(s): Cellular and Molecular Immunology, Abbas, et .al, 4th edition

CURRENT CONCEPTS IN VIROLOGY M6163 Credit Hours

Coordinator(s): Drs . Charles Hwang and Microbiology & Immunology FacultyPrerequisite(s): Microbiology and Cell and Molecular BiologyPeriod Offered: Spring Course Description: The structure, function and replication of important virus groups will be studied . Current research topics and techniques will be reviewed, with an emphasis on molecular biology and viral pathogenesis . Time, day and location TBA .Textbook(s): Selected Papers and TBA

DIRECTED INDIVIDUAL STUDY IN MICROBIOLOGICAL AND IMMUNOLOGICAL RESEARCH METHODS M623Variable Credit

Coordinator(s): Dr . Rosemary Rochford Microbiology & Immunology FacultyPrerequisite(s): The course is limited to students studying for a degree in Microbiology and Immunology, or to others by special arrangement with the Department Graduate Program Director .Period Offered: This course is offered Fall/Spring by arrrangement Course Description: This is a special research training program designed to acquaint students with specific areas of research and/or use of methods, techniques, or instrumentation, as well as to introduce students intensively to the laboratory, and research approaches .Textbook(s): None

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SEMINAR AND JOURNAL CLUB IN MICROBIOLOGY AND IMMUNOLOGY M6242 Credit Hours

Coordinator(s): Dr . Michael Princiotta and Microbiology/Immunology FacultyPrerequisite(s): Past or current Microbiology and Immunology course, or by permission of course coordinatorPeriod Offered: Fall/SpringCourse Description: Faculty and students will present their research work, or lead a Journal Club discussion in a selected subject area . Meetings will be twice weekly lasting 60 minutes per session . Grading will be based upon participation and oral contributions to discussion, as well as individual presentations .Textbook(s): None

METHODS OF MICROBIOLOGY AND IMMUNOLOGY RESEARCH M626Variable Credit

Coordinator(s): Dr . Rosemary Rochford Microbiology & Immunology FacultyPrerequisite(s): GS612 Biomedical Sciences Laboratory Rotations, or by permission of course coordinatorPeriod Offered: Year round by arrangementCourse Description: Methods of Research used by the faculty are demonstrated . Problem design and research methods are emphasized . Course deals with individualized laboratory experience . Topics agreed upon by student and faculty sponsor .

INTRODUCTION TO VIROLOGY M6272 Credit Hours

Coordinator(s): Dr . Jennifer Moffat and Microbiology & Immunology FacultyPrerequisite(s): Course work in Biochemistry and Molecular BiologyPeriod offered: First half of spring semesterCourse Description: This is an introductory course in virology for graduate students . The objectives are to understand the structure and characteristics of viruses, their replication, interactions with the host, and applications in biomedical science . The material

will be presented as lectures and in discussion of primary research articles . Textbook(s): Principles of Virology: Molecular Biology, Pathogenesis, and Control. 3rd Ed .,S .J . Flint, et al, 2008, ASM Press .Location: Room 3109 Weiskotten Hall

INTRODUCTION TO IMMUNOLOGY M6282 Credit Hours

Coordinator(s): Dr . Steve Taffet and Microbiology & Immunology FacultyPrerequisite(s): Course work in Biochemistry and Molecular BiologyPeriod offered: Second half of spring semesterCourse Description: This course is intended to be an introductory course in immunology for graduate students . The course goal is to develop a general understanding of immunology including both adaptive and innate immunity . Sixteen lectures will present basic concepts in immunology . In addition there will be fourteen sessions in which a journal article will be discussed which relates to the topic of the preceding lecture .Grades: Eighty percent of the grade will be determined by the average score of three exams and twenty percent of grade will be determined by class participation in discussion of journal articles .Textbook(s): Immunobiology, Vol 7 by Charles A . Janeway, Paul Travers, Mark Walport, and Mark ShlomchikLocation: Room 3113 Weiskotten Hall

RESEARCH IN MICROBIOLOGY M700Variable Credit

Coordinator(s): Dr . Charles Hwang, Microbiology & Immunology Staff & Adjunct FacultyPrerequisite(s): NonePeriod Offered: Fall/SpringCourse De sc ript ion: Or iginal research in microbiology for the master’s thesis or doctoral dissertation .Textbook(s): None

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M D and Ph D CoursesRESEARCH DESIGN FOR PHYSICIAN-SCIENTISTS MDPH 6013 Credit Hours

Coordinator(s): Drs . Barry Knox and Steven YoungentobPrerequisite: MD/PhD students in MSII yearPeriod offered: FallCourse description: This course promotes the development of critical scientific writing important to the students’ future career as physician-scientists . The student will gain experience in grantsmanship by writing and presenting an original hypothesis-based research proposal . Students will learn the essential features of scientific writing, with the emphasis on developing skills necessary for crafting an effective grant proposal . In the first part of the course the essentials of clear, unambiguous scientific writing will be highlighted through examples and written exercises . The elements of good and bad scientific writing will be discussed and compared . In the second part of the course the important features of writing a grant proposal will be reviewed . Students will write a grant proposal in their area of interest, with help from the Instructors and their thesis advisors [if chosen] . Attention to incorporating the aspects of clinical training and the translational aspects of the research proposal will be emphasized . Proposals will follow the typical NIH proposal format for MD/PhD pre-doctoral fellowships . Students will read and review each other’s proposals, thus gaining experience in the art of reviewing .Scheduling: The first month of the course will initially consist of three 90-minute sessions of the entire class . Subsequent meetings will be on an individual basis (by arrangement) for approximately 1 hour every 2 weeks .Course objectives:

(1) develop a cogent, hypothesis-based research proposal that constitutes a “first draft” for their thesis work as well as a proposal to be submitted for extramural funding .

(2) give a clear, compelling oral presentation of the proposal and defend it .

Grading: The course will use a satisfactory/unsatisfactory grading format . Grades will be based on effort and improvement on the exercises and assignments .

NeuroscienceINTRODUCTION TO NEUROSCIENCE (SAME AS A507) N5073 Credit Hours

Coordinator(s): Dr . Russell Durkovic, Director Dr . Dennis Stelzner, Co-DirectorPeriod Offered: Spring or summerCourse Description: The Systems Neuroscience course will consist of the Neuroscience course given to first year medical students, without the neuroanatomy components .This course will include the study of systems of neuroscience, including sensory, motor, limbic systems, sleep and awakening, and basic cognitive processing . The summer session will be a combination of video presentations and live tutorials . There will be 2 essay/multiple choice exams .

NEUROSCIENCE (SU: ECS NEU 601) N6013 Credit Hours

Coordinator(s): Dr . Mary Lou Vallano, Dr . Daniel Ts’o & Neuroscience Program Faculty, SU FacultyPeriod Offered: SpringCourse Description: Detailed analysis of the anatomy, physiology, and chemistry of the nervous system and behaviors that it mediates . Topics include: neurons and electrochemical properties of neurons, sensory and motor systems, homeostasis, sleep, consciousness, learning, and memory .Textbook(s): Neuroscience (4th Edition), D . Purves et al . Sinauer (2008) ISBN 0-87893-725-0 .

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CELL PHYSIOLOGY OF EXCITABLE CELLS (Same as PHA602 & PHY602) N6022 Credit Hours

Coordinator(s): Dr . Richard Veenstra, Director (Pharmacology) Dr . Jeffrey Freedman (Neuroscience & Physiology) Dr . Eduardo Solessio (Ophthalmology)Prerequisite(s): First Year Core CurriculumPeriod Offered: SpringCourse Description: This course will cover the key concepts ion transporter and ion channel function in determining the resting and action potential properties of living cells . The Instructor(s): will provide lectures on the Hodgkin-Huxley model for the nerve action potential, theories for electrodiffusion and ion permeation, and visual transduction . The remainder of the course will be primarily student led discussions of selected chapters from the CellPhysiology Sourcebook with the guidance of the course Instructor(s): . Grades are based on student presentation and participation in the selected chapter discussions . There is no course examination .Textbook(s): Sperelakis, N ., Cell Physiology Course Book, 3rd Ed ., 2001

TOPICS IN SIGNALING IN THE AUTONOMIC AND CENTRAL NERVOUS SYSTEMS N6032 Credit Hours

Coordinator(s): Dr . M . L . Vallano, Neuroscience Dr . R . Wojcikiewicz, PharmacologyPrerequisite(s): Core Curriculum Period Offered: FallCourse Description: This advanced course will cover 2-3 topics in receptors and cell signaling; for example G-protein-coupled receptors, integrins and cell adhesion, glutamate receptor signaling and LTP, CDKs with emphasis on the neural specific CDK5, ras signaling and tyrosine kinase-linked receptors, scaffolding proteins . Topics will be covered by a combination of graduate student-specific lectures and tutorials, based on current research papers and associated reviews . Each topic will also include a take-home essay type examination . This course covers the essential features of the autonomic nervous system in humans, and agents that modify this system, including therapeutic and recreational drugs and

toxic agents . The course will be composed of a combination of graduate student-specific lectures and tutorials together with selected lectures from the Medical School Pharmacology course (50PHA) .A minimum of two students must register for this course to be offered .Textbook(s): NONE - Selected Readings

TOPICS IN DEVELOPMENTAL NEUROBIOLOGY N6102 Credit Hours

Coordinator(s): Dr . S . Mooney, Dr . Rick Matthews (Coordinators); and other Neuroscience FacultyPrerequisite(s): N601 Neuroscience (completed or currently enrolled) or by arrangement with facultyPeriod Offered: Spring, even years (Session II: March-June)Course Description: This course is a half semester course, eight weeks in length, and will run in the second half of the spring semester, even years . Two two-hour sessions will be scheduled per week . This is primarily a reading course . Students will meet with the faculty twice per week to discuss questions or issues presented by the student . There will be a written exam at the end of the course .This course will provide extensive, yet selective, exposure to major issues and events in the development of the nervous system . Topics include: Axis determination and early patterning, Developmental signals and gene regulation, Cell generation/proliferation, Cell migration and guidance, Cell death, Synaptogenesis, and Plasticity .

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TOPICS IN VISION I N6162 Credit Hours

Coordinator(s): Dr . Eduardo SolessioPrerequisite(s): Introductory (e .g ., undergraduate) neuroscience and N623 Systems Neuroscience is strongly encouraged .Period Offered: Late Spring of odd numbered years; By arrangement onlyCourse Description: The course will examine neuroanatomical, electrophysiological, and psychophysical aspects of vision . This is primarily a readings course, with emphasis on original literature . It is particularly appropriate for graduate students intending to conduct original research in the visual system . This first half will focus on visual mechanisms at the level of the retina, and will be offered on odd numbered years .Course Format: The course will largely consist of discussion sessions covering extensive readings of original scientific literature . Grades will be based on class participation .

METHODS OF NEUROSCIENCE RESEARCH N617Variable Credit

Coordinator(s): Dr . Steven Youngentob and Neuroscience FacultyPrerequisite(s): 612GS Biomedical Sciences Laboratory Rotations or permission of InstructorPeriod Offered: Year round by arrrangement onlyCourse Description: Methods of research used by the faculty are demonstrated . Problem design andresearch methods are emphasized . Course deals with individualized laboratory experience . Topics agreed upon by student and faculty sponsor .Textbook(s): None

TOPICS IN VISION II N6182 Credit Hours

Coordinator(s): Dr . Daniel Ts’o (Director) and Dr . Brad MotterPrerequisite(s): Introductory (e .g ., undergraduate) neuroscience and N623 Systems Neuroscience is strongly encouraged .Period Offered: Spring; By arrangement only

Course Description: The course will examine neuroanatomical, electrophysiological, and psychophysical aspects of vision . This is primarily a readings course, with emphasis on original literature . It is particularly appropriate for graduate students intending to conduct original research in the visual system . This second half will focus on visual mechanisms beyond the level of the retina, focusing on the cortical contributions to visual processing and visually-guided behavior . Course Format: The course will largely consist of discussion sessions covering extensive readings of original scientific literature . Grades will be based on class participation .

NEUROBIOLOGY OF DISEASE N6192 Credit Hours

Course Director: Dr . Eric OlsonCoordinator(s): Basic Science and Clinical Departments FacultyPrerequisite(s): GS616 Foundations of Molecular & Cellular Biology or permission of instructorPeriod Offered: Spring, odd years (Session II, March – June .)Course Description: Neurobiology of Disease will meet twice per week, Mondays and Fridays, 2:00 – 4:00 P .M . Each meeting will focus on one disease where some of the molecular underpinnings are understood (e .g . Alzheimer’s Disease) . The first hour of class will be led by a research scientist or physician with expertise in the basic biology of the disease . The class will discuss one review article and important research papers on the molecular mechanism of the disease . The second hour of class will be conducted by a clinician and the students will be introduced to the clinical dimensions of the disease .Textbook(s): None

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ADVANCED TOPICS IN RECEPTORS AND CELL SIGNALING (SAME AS PHY620) N6201 Credit Hour

Coordinator(s): Dr . M . L . VallanoPrerequisite(s): First year core curriculum; although not required, Autonomic Pharmacology 619PHA is strongly recommended .Period Offered: FallCourse Description: This advanced course will cover a topic in receptors and cell signaling; for example, G-protein-coupled receptors, integrins and cell adhesion, glutamate receptor signaling and LTP, CDKs with emphasis on the neural-specitlc CDK5, ras signaling and tyrosine kinase-linked receptors, scaffolding proteins, Topics will be covered by a combination of graduate student-specific lectures and tutorials, based on current research papers and associated reviews . Each topic will also include a take-home essay-type examination . Although it is not required, it is highly recommended that this course be taken in sequence with 619PHA-Autonomic Pharmacology . A minimum of 2 students must register for this course to be offered .Textbook(s): None - selected readings will be assigned

NEUROANATOMY LAB (SAME AS A621) N6212 Credit Hours

Coordinator(s): Dr . Dennis Slelzner and other Neuroscience FacultyPrerequisite(s): N507/A507 or N601 or by permission of instructorPeriod Offered: SpringCourse Description: This course will provide students the opportunity to dissect the human brain and gain an appreciation for three-dimensional organization in the central nervous system .Textbook(s): None .

CRITICAL ANALYSIS OF NEUROSCIENCE COMMUNICATIONS N622½ Credit/ Semester, 1 Credit/Academic Year

Coordinator(s): Dr . M .L . Vallano and Neuroscience program facultyPeriod Offered: Fall + Spring, full academic yearCourse description: This is a neuroscience seminar/journal club course utilizing lectures and published manuscripts by NIH WALS (Wednesday Afternoon Lecture Series) speakers in conjunction with external speakers in the departmental seminar series . Students will attend a total of 12 pre-lecture manuscript presentations using a journal club format (~1 hour) plus associated lectures/seminars (~1 hour) . This will take place during the fall and spring semesters of each academic year . Each student will prepare and present one pre-lecture manuscript to other students under the guidance of a faculty facilitator who is knowledgeable in the topic . All students will read and be fully prepared to discuss the selected manuscript prior to the pre-seminar . The course coordinator, together with the faculty facilitator, will provide constructive feedback to the student presenter . For departmentally sponsored lectures, students will meet with the lecturer during a post-seminar luncheon .

SYSTEMS NEUROSCIENCE N6233 Credit Hours

Coordinator(s): Drs . Daniel Ts’o, Frank MiddletonInstructor(s): Drs . Daniel Ts’o, Frank Middleton and Neuroscience FacultyPeriod Offered: FallCourse Description: An in-depth analysis of original literature readings with an emphasis on systems neuroscience, including sensory and motor systems learning, memory and cognition . Intended to provide a solid foundation for upper-level Topics courses in the Neurosciences .Textbook(s): Kandel, Schwartz and Jessell & original research papers (http: systems.neurosci.info)

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TOPICS IN CELLULAR AND MOLECULAR NEUROBIOLOGY N6532 Credit Hours

Coordinator(s): Dr . M . L . Vallano, NeurosciencePrerequisite(s): Core Curriculum and N603 (or equivalent) or by arrangement with faculty .Period Offered: by arrangementCourse Description: This course will discuss major issues in Molecular and Cellular Neurobiology, emphasizing contemporary approaches .Textbook(s): To be announced .

TOPICS IN SENSORY SYSTEMS N6542 Credit Hours

Coordinator(s): Dr . Eduardo Solessio Prerequisite(s): Neuroscience, or by arrangement with the facultyPeriod Offered: Spring by arrrangement onlyCourse Description: This course will examine neuroanatomical, electrophysiological, and psychophysical aspects of a particular sensory system, e .g ., vision, audition, touch, pain, and olfaction .This is primarily a readings course, with emphasis on original literature . Students will meet with one or more of the Instructor(s) to discuss questions or issues presented by the student . A set of questions and objectives will be distributed at the beginning of the course to help focus the students as they progress through the course . There will be written essay exams during the course, which will be based on the readings and course objectives .Textbook(s): Gordon L . Fain, Sensory Transduction

RESEARCH ROTATIONS IN NEUROSCIENCE N6751-5 Credit Hours

Coordinator(s): Dr . Steven Youngentob and Neuroscience facultyPrerequisite(s): Approval of the Neuroscience Program and involved faculty membersPeriod Offered: Offered year round by arrrangement Course Description: Methods of research used by the faculty are demonstrated . Problem design and research methods emphasized .Course deals with individualized laboratory experience . Topics agreed upon by student and faculty sponsor .Textbook(s): None

RESEARCH IN NEUROSCIENCE N700Variable Credit

Coordinator(s): Dr . Steven Youngentob and Neuroscience facultyPrerequisite(s): NonePeriod Offered: Fall/SpringCourse Description: Original dissertation research in Neuroscience under supervision of a Neuroscience faculty member and monitored by an advisory committee .Textbook(s): None

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PharmacologyPHARMACOLOGY PHA5407 Credit Hours*

Coordinator(s): Drs . S . Grassl, J . SteinPrerequisite(s): Core Curriculum and Medical PhysiologyPeriod Offered: FallCourse Description: This course emphasizes the basic principles of drug action as related to modern therapeutics . The course is organized in seven units based upon organ systems and aligned with similar subject matter taught in other second year courses . Each unit includes relevant lectures, a problem solving session, and a clinical case presentation . The role of the faculty is to support students in learning pharmacology and in gaining a foundation upon which to build a rational approach to the use of drugs in clinical practice .Textbook(s): Recommended: Goodman and Gilman’s, The Pharmacological Basis Of Therapeutics

CELL PHYSIOLOGY OF EXCITABLE CELLS (SAME AS N602 & PHY602) PHA6022 Credit Hours

Instructor(s): Dr . Richard Veenstra, Director (Pharmacology) Dr . Jeffrey Freedman (Neuroscience & Physiology) Dr . Eduardo Sollessio (Ophthalmology)Prerequisite(s): First Year Core CurriculumPeriod Offered: SpringCourse Description: This course will cover the key concepts ion transporter and ion channel function in determining the resting and action potential properties of living cells . The Instructor(s): will provide lectures on the Hodgkin-Huxley model for the nerve action potential, theories for electrodiffusion and ion permeation, and visual transduction . The remainder of the course will be primarily student led discussions of selected chapters from the CellPhysiology Sourcebook with the guidance of the course Instructor(s) . Grades are based on student presentation and participation in the selected chapter discussions . There is no course examination .Textbook(s): Sperelakis, N ., Cell Physiology Course Book, 3rd Ed ., 2001

PRINCIPLES OF PHARMACOLOGY PHA6101 Credit Hour

Coordinator(s): Drs . Richard Veenstra and Arkadii PertsovPrerequisite(s): First year Core CurriculumPeriod Offered: FallCourse Description: This advanced course will cover and analyze the fundamental principles of Pharmacology at the cellular and molecular levels . Topics covered will be kinetics of drug distribution and elimination, as well as agonism, antagonism, co-operativity and desensitization . It will consist of a combination of graduate student-specific lectures and tutorials together with selected lectures from the Medical School Pharmacology course (540PHA) . The course may be taken in conjunction with other Pharmacology modules . A minimum of two students must register for this course to be offered . Examinations will be in essay format .Textbook(s): None - selected readings will be assigned

CARDIOVASCULAR PHYSIOLOGY AND PHARMACOLOGY PHA6121 Credit Hour

Coordinator(s): Dr . A . PertsovPrerequisite(s): First year Core CurriculumPeriod Offered: FallCourse Description: This advanced course will detail and analyze current knowledge in cardiovascular science . Topics covered will be the molecular, cellular and electrophysiological bases of cardiovascular function, and the cellular and molecular mechanisms of drugs used to treat hypertension, myocardial ischemia, heart failure and complex cardiac arrhythmias . It will consist of a combination of graduate student-specific lectures and tutorials together with selected lectures from the Medical School Pharmacology course (540PHA) . A minimum of two students must register for this course to be offered . Examinations will be in essay format .Textbook(s): None - selected readings will be assigned

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APOPTOSIS AND CANCER PHARMACOLOGY PHA6152 Credit Hour

Coordinator(s): Drs . M .S . Sheikh and Y . HuangPrerequisite(s): First year Core CurriculumPeriod Offered: SpringCourse Description: This advanced course will cover current concepts in apoptosis and cancer pharmacology, and will specifically address the molecular actions of anti-cancer agents with emphasis on death ligands/receptors, apoptotic machinery, tumor suppressor genes, oncogenes, molecular mechanisms of chemoprevention and anti-cancer drug resistance, novel anticancer drug targets and emerging anti-cancer therapies . It will consist of a combination of graduate student-specific lectures and tutorials . Textbook(s): None - selected readings will be assignedLocation: Room 3113 Weiskotten Hall

METHODS OF PHARMACOLOGY RESEARCH PHA617Variable Credit

Coordinator(s): Dr . Y . Huang Pharmacology FacultyPrerequisite(s): GS612 Biomedical Sciences Laboratory Rotations or permission of InstructorPeriod Offered: Year round by arrrangement onlyCourse Description: Methods of research used by faculty are demonstrated . Problem design and research methods are emphasized .Outline: Course deals with individualized laboratory experience . Topics agreed upon by student and faculty sponsor .Textbook(s): None

CURRENT TOPICS IN PHARMACOLOGY PHA6181 Credit Hour

Coordinator(s): Dr . Y . Huang Pharmacology FacultyPrerequisite(s): 610PHAPeriod Offered: Year round by arrrangement onlyCourse Description: The purpose of this tutorial course is to develop a student’s knowledge of

Pharmacologic research as well as to provide an opportunity for focussed study in areas of cell and molecular pharmacology not otherwise covered in the graduate curriculum . The course format may include selected readings, discussions with faculty, seminars, and lectures . Course content should be discussed with the acuity mentor prior to enrollment in the class . Examination will be in the form of a written essay or public seminar, as determined by the course faculty .

AUTONOMIC PHARMACOLOGY PHA6191 Credit Hour

Coordinator(s): Dr . WojcikiewiczPrerequisite(s): First year core curriculumPeriod Offered: FallCourse Description: This course covers the essential features of the autonomic nervous system in humans, and agents that modify this system, including therapeutic and recreational drugs and toxic agents . The course will be composed of a combination of graduate student-specific lectures and tutorials together with selected lectures from the Medical School Pharmacology course (540PHA) .Tex t book(s): Goodman and Gilman’s , The Pharmacological Basis of Therapeutics

CANCER BIOLOGY AND THERAPEUTICS PHA6211 credit

Coordinator(s): Dr . Ying HuangInstructor(s): Drs . Ying Huang, M . Golam Mohi, M . Saeed SheikhPrerequisite(s): First Year Core CurriculumPeriod Offered: Fall, Odd YearsCourse Description: This advanced course covers most recent advances in cancer biology and anticancer drug discovery . Major emphasis is on signaling events involving kinases, phosphatases and other pertinent molecules as they relate to cancer development and progression . Emphasis is also on novel anticancer agents that target the signaling events and molecules linked to cancer development and progression . Course format involves didactic lectures and discussions of primary literature .

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PHARMACOLOGY SEMINAR PHA6450 Credit Hours

Coordinator(s): Dr . Y . Huang Pharmacology FacultyPrerequisite(s): NonePeriod Offered: Fall/SpringCourse Description: Graduate students and faculty will meet every week during the academic year to participate in seminars . Seminars will be given by outside speakers and Departmental members, including Graduate Students who, after their first year, will be required to give one presentation per year . Grades will be assigned based on performance . Thurs ., 12:00 - 1:00 PM Room 3105 Weiskotten HallTextbook(s): None

PHARMACOLOGY LABORATORY ROTATIONS PHA653Variable CreditCoordinator(s): Dr . Y . Huang Pharmacology FacultyPrerequisite(s): Course is limited to students studying for a degree in Pharmacology, or by special arrangement .Period Offered: Fall/Spring by arrrangementCourse Description: Students learn methods of research used by the Pharmacology Faculty . Problem design, research methods and the preparation of a written report are emphasized .This course is not offered for thesis or dissertation research, which is course 700PHA .Textbook(s): None

RESEARCH IN PHARMACOLOGY PHA700Variable Credit

Coordinator(s): Dr . Y . Huang Pharmacology FacultyPrerequisite(s): Approval of the departmentPeriod Offered: Fall/SpringCourse Description: Original dissertation research in Pharmacology under the supervision of a Pharmacology Faculty member and monitored by an advisory committee .Textbook(s): None

Physiology ProgramCELL PHYSIOLOGY OF EXCITABLE CELLS (SAME AS N602 & PHA602) PHY6022 Credit Hours

Coordinator(s): Dr . Richard Veenstra, Director (Pharmacology) Dr . Jeffrey Freedman (Neuroscience & Physiology) Dr . Eduardo Solessio (Ophthalmology)Prerequisite(s): First Year Core CurriculumPeriod Offered: SpringCourse Description: This course will cover the key concepts ion transporter and ion channel function in determining the resting and action potential properties of living cells . The Instructor(s): will provide lectures on the Hodgkin-Huxley model for the nerve action potential, theories for electrodiffusion and ion permeation, and visual transduction . The remainder of the course will be primarily student led discussions of selected chapters from the CellPhysiology Sourcebook with the guidance of the course Instructor(s) . Grades are based on student presentation and participation in the selected chapter discussions . There is no course examination .Textbook(s): Sperelakis, N ., Cell Physiology Course Book, 3rd Ed ., 2001

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BIOMATERIALS AND MEDICAL DEVICES (SU COURSE BEN468/668) PHY6032 Credit Hours

Coordinator(s): Dr . Kenneth MannInstructor(s): SU Faculty 359 Link Hall, x-3064, 003A Link Hall MACROBUTTON HtmlResAnchor jmhasenw@syr .edu xxxwayfarer@lycos .comPeriod Offered: SpringClass Times & Location: T/Th 10 – 11:20 a .m . 210 Hinds HallCourse Description: This course is designed to be an introduction to the field of biomaterials and medical devices . The basic material science of metals, ceramics, polymers, and biological materials used in medical and dental applications will be presented . Major concepts will focus on structure-property relationships and the physical and mechanical properties of these important classes of materials . Other topics will include modes of materials degradation and failure, including metallic corrosion, wear and fretting, and polymer degradation . Issues related to the biocompatibility of materials and the performance of medical devices will also be presented . Our study of biocompatibility will focus on important surface and interfacial properties of biomaterials and the biological response of the human body to the presence of artificial materials . Finally, examples of specific implants and medical devices will be presented and studied both through lecture materials and group projects and presentations .Textbook(s): Biomaterials Science: An Introduction to Materials in Medicine. B .D . Ratner, A .S . Hoffman, F .J . Schoen, and J .E . Lemons (Eds .), Academic Press, 1996 .Other sources: Implantation Biology, The Host Response and Biomedical Devices, Ed . R .S . Graco, CRC Press, 1994Biomedical Applications of Polymeric Materials, Ed . T . Tsuruta, T . Hayashi, et al ., CRC Press, 1993Biomaterials: An Interfacial Approach, L .L . Hench, E .C . Ethridge, Academic Press, 1982Biomaterials Science, An Introduction, J .B . Park and R .L . Lakes, Plenum Press, 1992 .

METHODS OF PHYSIOLOGY RESEARCH PHY617Variable Credit

Coordinator(s): Dr . Steven Youngentob and Physiology FacultyPrerequisite(s): 612GS Biomedical Sciences Laboratory Rotations or permission of InstructorPeriod Offered: Year round by arrrangement onlyCourse Description: Methods of research used by the faculty are demonstrated . Problem design andresearch methods are emphasized . Course deals with individualized laboratory experience . Topics agreed upon by student and faculty sponsor .Textbook(s): None

ADVANCED TOPICS IN RECEPTORS AND CELL SIGNALING (SAME AS N620) PHY6201 Credit Hour

Coordinator(s): Dr . M . L . VallanoPrerequisite(s): First year core curriculum; although not required, Autonomic Pharmacology 619PHA is strongly recommended .Period Offered: FallCourse Description: This advanced course will cover a topic in receptors and cell signaling; for example, G-protein-coupled receptors, integrins and cell adhesion, neuromuscular junction and ACh receptors, glutamate receptor signaling and LTP, CDKs with emphasis on the neural-specitlc CDK5, ras signaling and tyrosine kinase-linked receptors, scaffolding proteins, Topics will be covered by a combination of graduate student-specific lectures and tutorials, based on current research papers and associated reviews . Each topic will also include a take-home essay-type examination .Although it is not required, it is highly recommended that this course be taken in sequence with 619PHA-Autonomic Pharmacology . A minimum of 2 students must register for this course to be offered .Textbook(s): None - selected readings will be assigned

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JOURNAL CLUB IN PHYSIOLOGY PHY6521 Credit Hour

Coordinator(s): Dr . R . Matthews and Physiology FacultyPrerequisite(s): Systems Physiology taken either previously or concurrentlyPeriod Offered: by arrangementCourse Description: This course is designed to be taken concurrently with Systems Physiology, although it could also be taken one year later . It consists of six sessions, each lasting approximately two hours . Students will present and discuss assigned journal articles dealing with topics currently being discussed in the lecture course in Systems Physiology . Sessions will cover cardiovascular physiology (2), respiratory physiology (1), renal physiology (1), gastrointestinal physiology (1) and endocrine physiology (1) .Textbook(s): Assigned journal articles

SYSTEMS PHYSIOLOGY PHY6576 Credit Hours

Coordinator(s): Dr . Jeffrey FreedmanPrerequisite(s): NonePeriod Offered: FallCourse Description: This is a course consisting of about 70 lectures (plus demonstrations and laboratories) contained in the medical college course Mammalian Physiology . The lectures cover material in cardiovascular, respiratory, renal, gastrointestinal and endocrine physiology . Exams follow each of the units .The course begins in November and continues through March . Lectures will follow the lecture schedule of the College of Medicine course in Mammalian Physiology .Textbook(s): To be assigned

DIRECTED INDIVIDUAL STUDY IN PHYSIOLOGICAL RESEARCH METHODS PHY658Variable Credit

Coordinator(s): Dr . Steven Youngentob and Neuroscience & Physiology FacultyPrerequisite(s): Course is limited to students in Neuroscience & Physiology, or by special arrangementPeriod Offered: Fall/Spring by arrrangementCourse Description: This is a special research training program designed to acquaint students with specific areas of research and/or the use of methods, techniques and instrumentation . This course is not offered for thesis or dissertation research, which is course 700PHY .Textbook(s): None

PHYSIOLOGY SEMINAR PHY6591 Credit Hour

Coordinator(s): Dr . Steven Youngentob and Neuroscience & Physiology FacultyPrerequisite(s): Must be a Physiology graduate studentPeriod Offered: Fall/SpringCourse Description: Graduate students and faculty will meet once every other week during the academic year for the purpose of discussing current topics in neuroscience and physiology and departmental research programs . Outside speakers also participate . Each graduate student is required to present a critical review of a topic in biology during a scheduled meeting .Textbook(s): None

RESEARCH IN PHYSIOLOGY PHY700Variable Credit

Coordinator(s): Dr . Steven Youngentob and Neuroscience & Physiology facultyPrerequisite(s): Physiology graduate studentPeriod Offered: Fall/SpringCourse Description: Independent research in preparation for dissertation requirement .Textbook(s): None

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Additional CoursesGRANT WRITING GS6053 Credit Hours

Coordinator(s): Edward J . Shillitoe, PhDPrerequisite: Must have chosen a thesis advisorPeriod offered: SpringCourse description: Students will learn the essential features of technical writing, with an emphasis on grant proposals . In the first half of the course the essentials of clear, unambiguous writing will be presented in lectures, and be accompanied by written exercises . Examples of good and bad writing will be discussed and compared . The important features of grant proposals will be presented and studied . In the second half of the course the students will write a grant proposal in their area of interest, with help from the Instructor and from their thesis advisors . Proposals will be 10 pages long, divided into the same sections as a typical NIH or NSF proposal . At the end of the course students will read and review each other’s proposals, thus gaining experience in the art of reviewing . The grade for the course will be based on effort and improvement . These will be judged by performance on the exercises, assignments and class discussions .

SYSTEMS BIOLOGY OF GENETICS, GENOMICS AND PROTEOMICS GS6284 Credit Hours

Course Coordinator: Dr . David AmbergPrerequisite(s): GS616 Foundations of Molecular and Cellular Biology GS617 Introduction to Applied Biostatics and Research DesignPeriod Offered: Spring, odd yearsCourse Description: The goal of this course is to train graduate students in modern experimental and theoretical methods to perform systems level investigations into modern questions in genetics, genetic influences on human disease and gene expression . The course is divided into 4 sections with 4 exams . The focus of section 1 is to provide the student with a basic understanding of the genetics of inheritance, how to study complex genetic interactions and how genomic approaches can be used to define genetic networks . The focus of section 2 is on genome organization, evolution, and population genetics . Section 3 considers linkage and association analysis for identifying genetic influences on human disease, QTL studies, mouse genetics, and the use of microarrays for systems level expression analysis, linkage analysis and network construction . The course finishes with a comprehensive coverage of protein identification and sequencing by mass-spectrometry, proteome identification by mass-spectrometry, and data analysis of proteome data for delineation of protein complexes and expression profiling . Location: Room 3109 Weiskotten Hall

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SPREADSHEET ANALYSIS OF BIOLOGICAL DATA GS6573 Credit Hours

Coordinator(s): Douglas R . Robertson, PhDPrerequisite(s): Second year Graduate students with some familiarity with the operation of computers, especially PC-Windows platforms . Prior experience may include basic PC and Windows 2000 operating procedures taught through Educational Communications .Period Offered: SpringCourse Description: The goal of this course is to introduce Second year graduate students to a spreadsheet application (Excel™ 2003) of great flexibility that will allow a mechanism to organize, record, analyze and graph experimental data . Students become familiar with basic statistical and mathematical formulas and the corresponding Excel built-in function formulas, including use of built-in Macro functions (t-test, ANOVA, etc .), and graphing procedures using ChartWizard™ . Students are taught how to set-up and test model spreadsheet applications as a process in designing experimental protocols . Proper organization of data and analysis outcomes facilitates export of data to other higher level graphing and statistical package programs .The course consists of 10 Units that introduce concepts of basic statistics, linear, non-linear, exponential, inverse and curvilinear functions, dose-response and assay procedure, multivariant and morphometric analysis .Students are expected to attend all lectures and present a working spreadsheet application at the end of the course (a maximum of 10 students allowed) . Wed ., 10:00 A .M . - 12:00 PM, Room 220, LibraryTextbook(s): Written by the Instructor includes application template worksheets and CD or DVD R-W with templates .

ETHICS AND THE HEALTH PROFESSIONS CCFM 6402 3 Credit Hours

Instructor(s): Robert W . Daly, MD, SUNY Robert Flower, PhD, LMCPeriod offered: FallPrerequisite(s): CCM courses are open to upper division undergraduates, graduate students, faculty from the cooperating institutions, and members of the public who hold Bachelor’s Degrees . For members of the public, permission of the instructor is required .Course Description: This course examines the origins and use of ethical theories in the clinical, professional, organizational, and political-economic fields of action in health care . Specific issues presented in the context of case studies, illuminate the several fields . These issues include assisted suicide, professional codes of ethics, the ethics of “costcutting,” and justice with respect to care . Oral presentations, written commentaries on assigned readings, and a research paper are required .Wednesday 4-7 pm Room 1508 Sentor Building, SUNY Upstate

DISABILITY, MEDICINE, AND REPRESENTATION CCFM64173 credits

Instructor(s): Rebecca Garden, Ph .D ., Center for Bioethics and HumanitiesCourse Description: This course aims to bring disability and medicine into cross-disciplinary dialogue by examining representations of disability and medicine in film, literature, and medical texts on disability . These texts and conventions are considered in light of critical discussions of representation and disability . The “medicalization” of disability is examined, with students invited to explore disability and ability as cultural representations, wherein bodily abilities and limitations are conditioned by subjective perceptions of “normalcy .” A principal question is how to incorporate a “social model” of disability into medical/clinical education and practice . Disability studies scholars and clinicians working on disability will be guest speakers .

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MEDICINE IN LITERATURE AND FILM CCFM64233 credits

Instructor(s): Deirdre Neilen, Ph .D ., Center for Bioethics and HumanitiesCourse Description: The relationship between artistic creation and medicine will be explored through the study of novels, film, short stories, poetry, and essays about medical situations, characters and themes . Thematic areas to be examined include the relationship between truth and confidentiality; the hospital as toxic and therapeutic environment; relationships between health care workers and patients; illness as metaphor and as reality; and the experience of disease .

ORTHOPEDIC BASIC SCIENCE OBS6101 Credit Hours Hour/semester

Instructor(s): T .A . Damron, M .D . (Coordinator), and members of the Orthopedic Surgery and Research FacultyPrerequisite(s): Permission of course coordinatorPeriod offered: Fall/SpringCourse Description: This course is intended to provide a broad overview of basic musculoskeletal science for graduate studies . It is also taken by orthopedic residents and medical students with interest in orthopedics . Biweekly 1 hour lectures are given over the entire academic year by experts closest to their respective subjects . This course covers, in broad perspective, the basic principles that underlie the function of the elements of the musculoskeletal system including their form and function, growth and development, injury and repair . Topics include: articular cartilage, tendons, ligaments, skeletal muscle, bone, physeal function, intervertebral disc, molecular and cellular biology of bone and musculoskeletal tissues, peripheral nerve injury and repair, biomechanical fundamental bioelectricity, orthopedic biomaterials, genetics and the skeleton, prosthetics and orthotics, and principles of experimental design . While there are not stated Prerequisite(s): , prospective students should obtain permission of the course coordinator prior to registration .Textbook(s): Orthopedic Basic Science, S .R . Simon, edit ., American Academy of Orthopedic Surgeons

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FORMS AND REQUIREMENTS

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Student’s Name: Semester/Year Entered: 1. Required Graduate Courses: Credit Year Hours Completed Grade GS618 Responsible Conduct of Scientific Research (Research Ethics) I 1 GS619 Responsible Conduct of Scientific Research (Research Ethics) II 1 Additionalcoursesdeterminedinconsultationwithadvisor(seeelectivesuggestionsbelow) Elective Suggestions:

GS605 Grant Writing 3 GS616 Foundations of Molecular and Cellular Biology 4 GS617 Introduction to Applied Biostatistics and Research Design 2 GS657 Spreadsheet Analysis of Biological Data 3 GS628 Systems Biology of Genetics, Genomics and Proteomics 4 GS892 Introduction to the Presentation and Analysis of Scientific Literature: Journal Club 1 A505 Human Anatomy 9 A507 Introduction to Neuroscience 3 A517 Microscopic Anatomy 4 A613 Graduate Cellular Anatomy 2 A621 Neuroanatomy Lab 2 B649 Topics in Quantitative Biology 1 B664 Protein Sorting and Vesicular Trafficking 1 B666 Protein Structure Determination 2 N620 Advanced Topics in Receptors and Cell Signaling 1 N623 Systems Neuroscience 3 PHA615 Apoptosis and Cancer Pharmacology 2 PHA621 Cancer Biology and Therapeutics 1

2. Total Didactic Graduate (minimum of 20 credit hours): 3. Department Seminar Series (attendance required at all seminars)

4. Dissertation Committee Meetings (minimum of one meeting per year): Members: (Sponsor) Dates:

(Chair)

5. Dissertation Defense: Date: Final Approval Date:

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Student’s Name: Semester/Year Entered:

1. Required Graduate Courses: Credit Year Hours Completed Grade

GS604 Graduate Student Research Opportunities 0 GS605 Grant Writing 3 GS612 Biomedical Sciences Lab Rotations (2 credits each) 6 Rotation Labs:

GS616 Foundations of Molecular and Cellular Biology 4 GS617 Introduction to Applied Biostatistics and Research Design 2 GS618 Responsible Conduct of Scientific Research (Research Ethics) I 1 GS619 Responsible Conduct of Scientific Research (Research Ethics) II 1 GS892 Introduction to the Presentation and Analysis of Scientific Literature: Journal Club 1

1. Elective Suggestions: Credit Year Hours Completed Grade

GS657 Spreadsheet Analysis of Biological Data 3 GS628 Systems Biology of Genetics, Genomics and Proteomics 4 A505 Human Anatomy 9 A507 Introduction to Neuroscience 3 A517 Microscopic Anatomy 4 A613 Graduate Cellular Anatomy 2 A621 Neuroanatomy Lab 2 B647 Gene Expression and Epigenetic Regulation 3 B649 Topics in Quantitative Biology 1 B664 Protein Sorting and Vesicular Trafficking 1 B666 Protein Structure Determination 2 N620 Advanced Topics in Receptors and Cell Signaling 1 N623 Systems Neuroscience 3 PHA615 Apoptosis and Cancer Pharmacology 2 PHA621 Cancer Biology and Therapeutics 1

2. Total Didactic Graduate Courses (minimum of 30 credit hours): 3. Department Seminar Series (attendance required at all seminars)4. Qualifying Examination (to be completed by end of 5th semester): Date:

5. 30 min Departmental Seminar (to be presented within 6 mos. of qualifying exam): Date:

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6. Thesis Advisory Committee Meetings (minimum of one meeting per year):

Members: Dates:

(minimum 3 faculty members, including sponsor)

7. Dissertation Committee (minimum 6 faculty members including Thesis Advisory Committee members; maximum 3 members from the Dept of Cell and Dev Biology and at least one member from outside SUNY Upstate)

Members:

8. Dissertation Defense: Date: Final Approval Date:

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Student’s Name: Semester/Year Entered:

1. Required Graduate Courses: Credit Year Hours Completed Grade

GS616 Foundations of Molecular and Cellular Biology 4GS617 Introduction to Applied Biostatics and Research Design 2GS618 Responsible Conduct of Scientific Research (Research Ethics) I 1GS619 Responsible Conduct of Scientific Research (Research Ethics) II 1B609 Biochemistry & Molecular Biology Rotations 6or GS612 Biomedical Sciences Laboratory RotationsGS604 Graduate Student Research Opportunities 0GS892 Introduction to the Presentation and Analysis of Scientific Literature: Journal Club 2B620 Biochemistry Seminars 0B648 Research Design in Biochemistry & Molecular Biology 3B650 Scientific Writing 1

Advanced Courses:

At least 6 credits of Advanced Biochemistry & Molecular Biology Courses are required.

2. Total Didactic Graduate Courses (minimum of 30 credit hours):3. Qualifying Examination (to be scheduled during the summer following the student’s second year): Graduate Program Committee Approval: Examination Date and Results: 4. Dissertation Committee Meetings and Department Research Talk Meeting Letter Received (minimum of one meeting per year): Dates (Advisor)

Third Year:

Fourth Year:

Fifth Year:

5. Dissertation Defense: Date: Committee Approved:

DEPARTMENT OF BIOCHEMISTRY AND MOLECULAR BIOLOGYPhD Degree Requirements Checklist

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Student’s Name: Semester/Year Entered: 1. Required Graduate Courses: Credit Year Hours Completed Grade

GS616 Foundations of Molecular and Cellular Biology 4GS618 Responsible Conduct of Scientific Research (Research Ethics) I 1GS619 Responsible Conduct of Scientific Research (Research Ethics) II 1B609 Biochemistry & Molecular Biology Rotations 4GS892 Introduction to the Presentation and Analysis of Scientific Literature: Journal Club 1B620 Biochemistry Seminars 0

Advanced Courses:

At least 3 credits of Advanced Biochemistry & Molecular Biology Courses are required.

2. Total Didactic Graduate Courses (minimum of 20 credit hours):3. M.S. Thesis Committee Meetings (minimum of one meeting per year): Meeting Dates

First Year:

Second Year:

4. Thesis Defense: Date: Committee Approved:

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Student’s Name: Semester/Year Entered: 1. Required Graduate Courses: Credit Year First and second years: Hours Completed Grade GS604 Graduate Student Research Opportunities 0 GS612 Biomedical Sciences Laboratory Rotations (1st rotation) 2 GS616 Foundations of Molecular and Cellular Biology 4 GS617 Introduction to Applied Biostatistics and Research Design 2 GS618 Responsible Conduct of Scientific Research (Research Ethics) I 1 GS612 Biomedical Sciences Laboratory Rotations (2nd rotation) 2 GS612 Biomedical Sciences Laboratory Rotations (3rd rotation) 2 GS892 Introduction to the Presentation and Analysis of Scientific Literature: Journal Club 1 GS619 Responsible Conduct of Scientific Research (Research Ethics) II 1 M627 Intro to Virology 2 M628 Intro to Immunology 2 M616 Current Concepts in Virology 3 M610 Problems in Cell and Molecular Immunology 3 M624 Microbiology and Immunology Journal and Seminar Series 2 x 2 M623 Directed Individual Study in Micro. and Immuno. Research variable GS605 Elective: Grant Writing 3

Third Year & Following Years

M700 Research in Microbiology & Immunology M624 Microbiology and Immunology Journal and Seminar Series 2 credits each semesterEach student will assist in the Medical Microbiology laboratory courses (second, third, and possibly fourth, not the final thesis year).

2. Qualifying Examination: Schedule by the End of Year II The committee consists of at least three Microbiology and Immunology department faculty members and a minimum of

three outside-department faculty members. The exam is scheduled by the end of the second year, and can be taken in summer or early fall. Exam components: dissertation project proposal and a review of one of two questions submitted by the committee, and an oral examination. Two months are allowed to complete the proposal and to address the question before the oral examination.

Committee Members: (Name, Department) Sponsor / Advisor: (Cmte. Chair) Dean’s Approval of Cmte.: (Initials or date of approval notice)

Exam Date: Exam Outcome:

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3. Dissertation Advisory Committee: Chosen After Passing Qualifying Examination The committee consists of 5 on-campus members, including the Advisor (but not more than three may have primary appointments in the same department). The committee must meet at least twice per year during the dissertation research period, and committee must sign-off on student’s readiness to write & defend dissertation.

Committee Members: (Name, Department) Dept. Chair’s Approval: (Dissertation Advisor) (Initials or date of approval notice) Meeting Dates: Year III Year IV Year V Year VI

4. Submission of First-Author (or Co-First-Author) Research Paper: Students in Microbiology & Immunology are required to submit at least one first-author or co-first-author research paper for publication prior to the Dissertation Defense.

Journal submitted to: Date submitted: Current status: 5. Dissertation Defense Committee: Chosen by the Beginning of Final Year The committee consists of the 5 members of the

Dissertation Advisory Committee (including the Advisor), plus one off-campus member, and may be supplemented by additional members; final composition must be approved by the Dean.

Committee Members: (Name, Department) Dept. Chair’s Approval: (Cmte. Chair) (Initials or date of approval notice)

Dissertation Defense Date: Defense Outcome:

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Student’s Name: Semester/Year Entered: 1. Required Graduate Courses: Credit Year Hours Completed Grade

GS616 Foundations of Molecular and Cellular Biology 4 GS618 Responsible Conduct of Scientific Research (Research Ethics) I 1 GS619 Responsible Conduct of Scientific Research (Research Ethics) II 1 M627 Intro to Virology 2 M628 Intro to Immunology 2 M616 Current Concepts in Virology 3 M610 Problems in Cell and Molecular Immunology 3 M624 Microbiology and Immunology Journal and Seminar Series 4 x 2 M623 Directed Individual Study in Micro. and Immuno. Research variable GS605 Elective: Grant Writing 3 GS617 Elective: Introduction to Applied Biostatistics and Research Design 2

2. Degree Conferral

Date:

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Student’s Name: Semester/Year Entered: Credit Year1. Required Graduate Courses: Hours Completed Grade

GS618 Responsible Conduct of Scientific Research (Research Ethics) I 1 GS619 Responsible Conduct of Scientific Research (Research Ethics) II 1 M616 Current Concepts in Virology 3 M610 Problems in Cell and Molecular Immunology 3 GS617 Introduction to Applied Biostatistics and Research Design 2 M700 Research in Microbiology & Immunology variable M624 Microbiology and Immunology Journal and Seminar Series 2 x 2

2. Qualifying Examination: Schedule by the End of Year II The committee consists of at least three Microbiology and Immunology department faculty members and a minimum of

three outside-department faculty members. The exam is scheduled by the end of the second year, and can be taken in summer or early fall. Exam components: dissertation project proposal and a review of one of two questions submitted by the committee, and an oral examination. Two months are allowed to complete the proposal and to address the question before the oral examination.

Committee Members: (Name, Department) Sponsor / Advisor: (Cmte. Chair) Dean’s Approval of Cmte.: (Initials or date of approval notice)

Exam Date: Exam Outcome:

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3. Dissertation Advisory Committee: Chosen After Passing Qualifying Examination The committee consists of 5 on-campus members, including the Advisor (but not more than three may have primary appointments in the same department). The committee must meet at least twice per year during the dissertation research period, and committee must sign-off on student’s readiness to write & defend dissertation.

Committee Members: (Name, Department) Dept. Chair’s Approval: (Dissertation Advisor) (Initials or date of approval notice) Meeting Dates: Year III Year IV Year V Year VI

4. Submission of First-Author (or Co-First-Author) Research Paper: Prior to Defense Students in Microbiology & Immunology are required to submit at least one first-author or co-first-author research paper for publication prior to the Dissertation Defense.

Journal submitted to: Date submitted: Current status:

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5. Dissertation Defense Committee: Chosen by the Beginning of Final Year The committee consists of the 5 members of the Dissertation Advisory Committee (including the Advisor), plus one off-campus member, and may be supplemented by additional members; final composition must be approved by the Dean.

Committee Members: (Name, Department) Dept. Chair’s Approval: (Cmte. Chair) (Initials or date of approval notice)

Dissertation Defense Date: Defense Outcome:

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NEUROSCIENCE PROGRAMPh.D. Requirements Checklist

Student’s Name: Semester/Year Entered: Neuroscience is broad-based and rapidly expanding field that encompasses aspects of many scientific disciplines and crosses traditional departmental boundaries. This is reflected in the fact that faculty members participating in the Program come from many departments, basic science and clinical, and represent a variety of technical and theoretical approaches to the study of the nervous system. The Neuroscience Graduate Program is designed to provide each student with an understanding of contemporary issues in neuroscience through coursework and in-depth research training. Requirements for a PhD through the Neuroscience Graduate Program are listed below. Required didactic courses (minimum of 30 credits): Credit Year1. Core Curriculum Hours Completed Grade

FirstYear,Fall:

GS604 Graduate Student Research Opportunities 0 GS612 Biomedical Sciences Laboratory Rotations (1st Rotation) 2 GS616 Foundations of Molecular and Cellular Biology 4 GS617 Introduction to Applied Biostatistics and Research Design 2 GS618 Responsible Conduct of Scientific Research (Research Ethics) 1

FirstYear,Spring:

GS612 Biomedical Sciences Laboratory Rotations (2nd Rotation) 2 GS612 Biomedical Sciences Laboratory Rotations (3rd Rotation) 2 GS892 Introduction to the Presentation and Analysis of Scientific Literature: 1 Journal Club

SecondYear,Fall:

GS619 Responsible Conduct of Scientific Research (Research Ethics) II 1 Inaddition,studentsmusttakeadditionaladvancedelectives.2. Required Neuroscience Courses

N601 Neuroscience – Spring OR N507 Introduction to Neuroscience, SpringorSummer 3 N622 Critical Analysis of Neuroscience Communications, (peracademicyr) 1 FallandSpring,secondyear 3. Advanced Courses

Topicscourse-Eachstudentmusttakeaminimumof6creditsofadvancedneurosciencecourses.

N602 Principles of Membrane excitability - Spring,sessionI 2 N603 Topics in Signaling in the Autonomic and Central Nervous Systems Fall,sessionII 2 N610 Topics in Developmental Neurobiology – Spring,sessionII,evencalendaryears 2 N616 Topics in Vision I –Spring,byarrangement 2 N618 Topics in Vision II – Spring,byarrangementonly 2 N619 Neurobiology of Disease – Spring,sessionII,oddyears 2 N620 Advanced Topics in Receptors and Cell Signaling – Fall,sessionII 2 N621 Neuroanatomy Lab – Spring,sessionI 2 N623 Systems Neuroscience 3 N653 Topics in Cellular and Molecular Neurobiology –byarrangement 2 N654 Topics in Sensory Systems – Spring,byarrangement 2

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4. Additional courses: Selected based on each student’s interests and consultation with his/her advisor(s) and Program Coordinator/Director.

Presentations:

Each student in the Neuroscience Graduate Program is required to attend the complete seminar series and to present a seminar to the members of the Program each year. A final seminar will be presented as part of the oral defense of the student’s dissertation.

Qualifying Examination:

Each student must pass a PhD Qualifying Examination that includes written and oral sections. This is traditionally taken during the second half of the student’s second year.

Dissertation:

A written dissertation describing the student’s original research and an oral defense is required.

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Student’s Name: Semester/Year Entered: 1. Required Graduate Courses: Credit Year Hours Completed Grade

GS616 Foundations of Molecular and Cellular Biology 4 GS617 Introduction to Applied Biostatistics and Research Design 2 GS604 Graduate Student Research Opportunities 0 GS612 Biomedical Sciences Lab Rotations OR PHA653 Pharmacology Laboratory Rotations 6 GS618 Responsible Conduct of Scientific Research (Research Ethics) I 1 GS619 Responsible Conduct of Scientific Research (Research Ethics) II 1 GS605 Grant Writing 3 GS892 Introduction to the Presentation and Analysis of Scientific Literature: Journal Club 1

Pharmacology Courses

PHA610 Principles of Pharmacology* 1 PHA612 Cardiovascular Physiology and Pharmacology* 1 PHA602 Cell Physiology of Excitable Cells* 2 PHA615 Apoptosis and Cancer Pharmacology* 2 PHA618 Current Topics of Pharmacology* 1 PHA619 Autonomic Pharmacology* 1 PHA621 Cancer Biology and Therapeutics* 1 PHA540 Pharmacology 7 PHA645 Pharmacology Seminar (one per academic year) 0

* All Pharmacology PhD students must take either 4-6 credits of Pharmacology courses indicated with an asterisk (PHA610 is required) or PHA540.

2. Total Didactic Graduate Courses (minimumof30credithours):

3. Qualifying Examination (to be scheduled during the summer following the student’s second year): Graduate Program Committee Approval: Examination Date and Result:

4. Dissertation Committee Meetings(minimumofonemeetingperyear): Meeting Dates Grade

Third Year:

Fourth Year:

5. Dissertation Defense: Date: Committee Approved:

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PHYSIOLOGY PROGRAMPh.D. Requirements Checklist

Student’s Name: Semester/Year Entered: An undergraduate degree, either in the biological or physical sciences or in engineering, is required for admission into the graduate program leading to the Ph.D. Degree. Applicants are also expected to have completed undergraduate courses in biology, calculus, physics and organic chemistry

Required didactic courses (minimum of 30 credits): Credit Year1. Core Curriculum Hours Completed Grade

First Year

Fall GS604 Graduate Student Research Opportunities 0 GS612 Biomedical Sciences Laboratory Rotations (1st Rotation) 2 GS616 Foundations of Molecular and Cellular Biology 4 GS617 Introduction to Applied Biostatistics and Research Design 2 GS618 Responsible Conduct of Scientific Research (Research Ethics) I 1Spring GS612 Biomedical Sciences Laboratory Rotations (2nd Rotation) 2 GS612 Biomedical Sciences Laboratory Rotations (3rd Rotation) 2 GS892 Introduction to the Presentation and Analysis of Scientific Literature: Journal Club 1Second Year

FallGS619 Responsible Conduct of Scientific Research (Research Ethics) II 1Inaddition,studentsmusttakeadditionaladvancedelectives.

2. Required Physiology Courses

PHY657 Systems Physiology - Spring 6 PHY659 Physiology Seminar – Fall/Spring 1

3. Advanced CoursesSpecialty courses and biostatistics selected to support and enrich the student’s research area.Presentations: Each student in the Physiology Graduate Program is required to attend the complete seminar series and to present a seminar to the members of the Program each year. A final seminar will be presented as the oral part of the dissertation defense.Qualifying Examination: Soon after the completion of didactic course requirements, each student must pass a PhD Qualifying Examination that includes written and oral sections. This is traditionally taken at the end of the spring of the second year.Dissertation: A dissertation describing the results of original research is required along with an oral defense.

M.S. DegreeMaster Student programs are tailored to meet individual student needs.

MS students are required to take:First Year

Fall GS618 Responsible Conduct of Scientific Research 1Second Year

Fall GS619 Responsible Conduct of Scientific Research (Research Ethics) II 1AdditionalcoursesdeterminedbydegreegrantingprogramandAdvisor.

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College of Graduate StudiesWeiskotten Hall • 766 Irving Avenue Syracuse, New York 13210 • 315-464-4538

www.upstate.edu

F83165 Rev. 6/2010