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AIM: Where did life originate from?
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Page 1: 1.8

AIM: Where did life originate from?

Page 2: 1.8

AIM: Where did life originate from?

“…sparked by just the right combination of physical events & chemical processes…”

Page 3: 1.8

Bacteria Archae-bacteria

AnimaliaFungiProtista Plantae

4500

4000

3500

3000

2500

2000

500

1500

0

1000

Formation of earth

Molten-hot surface ofearth becomes cooler

Oldest definite fossilsof prokaryotes

Appearance of oxygenin atmosphere

Oldest definite fossilsof eukaryotes

First multicellularorganisms

Appearance of animalsand land plants

Colonization of landby animalsPaleozoic

Mesozoic

Cenozoic

Mill

ion

s o

f ye

ars

ago

AR

CH

EA

N PR

EC

AM

BR

IAN

PR

OT

ER

OZ

OIC

Page 4: 1.8

Bacteria Archae-bacteria

AnimaliaFungiProtista Plantae

4500

4000

3500

3000

2500

2000

500

1500

0

1000

Formation of earth

Molten-hot surface ofearth becomes cooler

Oldest definite fossilsof prokaryotes

Appearance of oxygenin atmosphere

Oldest definite fossilsof eukaryotes

First multicellularorganisms

Appearance of animalsand land plants

Colonization of landby animalsPaleozoic

Mesozoic

Cenozoic

Mill

ion

s o

f ye

ars

ago

AR

CH

EA

N PR

EC

AM

BR

IAN

PR

OT

ER

OZ

OIC

The evolutionary tree of life can be documented with evidence.The Origin of Life on Earth is another story…

Page 5: 1.8

What is Life?

Page 6: 1.8

What is Life?§ First we have to define LIFE…

Page 7: 1.8

What is Life?§ First we have to define LIFE…

u organized as cells

Page 8: 1.8

What is Life?§ First we have to define LIFE…

u organized as cellsu respond to stimuli

Page 9: 1.8

What is Life?§ First we have to define LIFE…

u organized as cellsu respond to stimuliu regulate internal processes

Page 10: 1.8

What is Life?§ First we have to define LIFE…

u organized as cellsu respond to stimuliu regulate internal processes

§ homeostasis

Page 11: 1.8

What is Life?§ First we have to define LIFE…

u organized as cellsu respond to stimuliu regulate internal processes

§ homeostasis

u use energy to grow

Page 12: 1.8

What is Life?§ First we have to define LIFE…

u organized as cellsu respond to stimuliu regulate internal processes

§ homeostasis

u use energy to grow§ metabolism

Page 13: 1.8

What is Life?§ First we have to define LIFE…

u organized as cellsu respond to stimuliu regulate internal processes

§ homeostasis

u use energy to grow§ metabolism

u develop

Page 14: 1.8

What is Life?§ First we have to define LIFE…

u organized as cellsu respond to stimuliu regulate internal processes

§ homeostasis

u use energy to grow§ metabolism

u develop § change & mature

within lifetime

Page 15: 1.8

What is Life?§ First we have to define LIFE…

u organized as cellsu respond to stimuliu regulate internal processes

§ homeostasis

u use energy to grow§ metabolism

u develop § change & mature

within lifetime

u reproduce

Page 16: 1.8

What is Life?§ First we have to define LIFE…

u organized as cellsu respond to stimuliu regulate internal processes

§ homeostasis

u use energy to grow§ metabolism

u develop § change & mature

within lifetime

u reproduce§ heredity

Page 17: 1.8

What is Life?§ First we have to define LIFE…

u organized as cellsu respond to stimuliu regulate internal processes

§ homeostasis

u use energy to grow§ metabolism

u develop § change & mature

within lifetime

u reproduce§ heredity

wDNA / RNA

Page 18: 1.8

What is Life?§ First we have to define LIFE…

u organized as cellsu respond to stimuliu regulate internal processes

§ homeostasis

u use energy to grow§ metabolism

u develop § change & mature

within lifetime

u reproduce§ heredity

wDNA / RNA

§ adaptation & evolution

Page 19: 1.8

The Origin of Life is Hypothesis

Page 20: 1.8

The Origin of Life is Hypothesis

Page 21: 1.8

The Origin of Life is Hypothesis§ Special Creation

Page 22: 1.8

The Origin of Life is Hypothesis§ Special Creation

u Was life created by a supernatural or divine force?

Page 23: 1.8

The Origin of Life is Hypothesis§ Special Creation

u Was life created by a supernatural or divine force?

u not testable

Page 24: 1.8

The Origin of Life is Hypothesis§ Special Creation

u Was life created by a supernatural or divine force?

u not testable§ Extraterrestrial Origin

Page 25: 1.8

The Origin of Life is Hypothesis§ Special Creation

u Was life created by a supernatural or divine force?

u not testable§ Extraterrestrial Origin

u Was the original source of organic (carbon) materials comets & meteorites striking early Earth?

Page 26: 1.8

The Origin of Life is Hypothesis§ Special Creation

u Was life created by a supernatural or divine force?

u not testable§ Extraterrestrial Origin

u Was the original source of organic (carbon) materials comets & meteorites striking early Earth?

u Heavy bombardment 4bya may have delivered organic compound and water to Earth

Page 27: 1.8

The Origin of Life is Hypothesis§ Special Creation

u Was life created by a supernatural or divine force?

u not testable§ Extraterrestrial Origin

u Was the original source of organic (carbon) materials comets & meteorites striking early Earth?

u Heavy bombardment 4bya may have delivered organic compound and water to Earth

u testable

Page 28: 1.8

The Origin of Life is Hypothesis§ Special Creation

u Was life created by a supernatural or divine force?

u not testable§ Extraterrestrial Origin

u Was the original source of organic (carbon) materials comets & meteorites striking early Earth?

u Heavy bombardment 4bya may have delivered organic compound and water to Earth

u testable§ Spontaneous Abiotic Origin

Page 29: 1.8

The Origin of Life is Hypothesis§ Special Creation

u Was life created by a supernatural or divine force?

u not testable§ Extraterrestrial Origin

u Was the original source of organic (carbon) materials comets & meteorites striking early Earth?

u Heavy bombardment 4bya may have delivered organic compound and water to Earth

u testable§ Spontaneous Abiotic Origin

u Did life evolve spontaneously from inorganic molecules?

Page 30: 1.8

The Origin of Life is Hypothesis§ Special Creation

u Was life created by a supernatural or divine force?

u not testable§ Extraterrestrial Origin

u Was the original source of organic (carbon) materials comets & meteorites striking early Earth?

u Heavy bombardment 4bya may have delivered organic compound and water to Earth

u testable§ Spontaneous Abiotic Origin

u Did life evolve spontaneously from inorganic molecules?

u testable

Page 31: 1.8

Origin of Organic Compounds

Page 32: 1.8

Origin of Organic Compounds

Possible locations that would have allowed the synthesis of organic compounds:

Page 33: 1.8

Origin of Organic Compounds

Possible locations that would have allowed the synthesis of organic compounds:

§ Hydrothermal vents deep in the ocean release chemicals, creating unusual chemical conditions

Page 34: 1.8

Origin of Organic Compounds

Possible locations that would have allowed the synthesis of organic compounds:

§ Hydrothermal vents deep in the ocean release chemicals, creating unusual chemical conditions

§ Extraterrestrial origin: Scientists have shown that organic compounds could have formed in cold interstellar space and then delivered to Earth by meteors or comets

Page 35: 1.8

Origin of Organic Compounds

Possible locations that would have allowed the synthesis of organic compounds:

§ Hydrothermal vents deep in the ocean release chemicals, creating unusual chemical conditions

§ Extraterrestrial origin: Scientists have shown that organic compounds could have formed in cold interstellar space and then delivered to Earth by meteors or comets

§ Chemical reactions in the atmosphere and in water, on the surface of the Earth

Page 36: 1.8

Spontaneous Origin of Life

Page 37: 1.8

Spontaneous Origin of LifePasteur disproved “spontaneous generation”

Page 38: 1.8

Spontaneous Origin of LifePasteur disproved “spontaneous generation”

Page 39: 1.8

Spontaneous Origin of LifePasteur disproved “spontaneous generation”

Oldest bacterial fossil date back to 1.9 bya

Page 40: 1.8

Spontaneous Origin of LifePasteur disproved “spontaneous generation”

Oldest bacterial fossil date back to 1.9 bya

Page 41: 1.8

Spontaneous Origin of LifePasteur disproved “spontaneous generation”

Oldest bacterial fossil date back to 1.9 bya

Processes that would have been needed for

Page 42: 1.8

Spontaneous Origin of LifePasteur disproved “spontaneous generation”

Oldest bacterial fossil date back to 1.9 bya

Processes that would have been needed forthe first cells to form include:

Page 43: 1.8

Spontaneous Origin of LifePasteur disproved “spontaneous generation”

Oldest bacterial fossil date back to 1.9 bya

Processes that would have been needed forthe first cells to form include:

1. Chemical reactions to produce simple organic molecules (ex. amino acids) from inorganic

molecules (ex. water, carbon dioxide)

Page 44: 1.8

Spontaneous Origin of LifePasteur disproved “spontaneous generation”

Oldest bacterial fossil date back to 1.9 bya

Processes that would have been needed forthe first cells to form include:

1. Chemical reactions to produce simple organic molecules (ex. amino acids) from inorganic

molecules (ex. water, carbon dioxide)

Page 45: 1.8

Spontaneous Origin of LifePasteur disproved “spontaneous generation”

Oldest bacterial fossil date back to 1.9 bya

Processes that would have been needed forthe first cells to form include:

1. Chemical reactions to produce simple organic molecules (ex. amino acids) from inorganic

molecules (ex. water, carbon dioxide)

2. Assembly of these organic molecules into polymers (ex. polypeptides)

Page 46: 1.8

Spontaneous Origin of LifePasteur disproved “spontaneous generation”

Oldest bacterial fossil date back to 1.9 bya

Processes that would have been needed forthe first cells to form include:

1. Chemical reactions to produce simple organic molecules (ex. amino acids) from inorganic

molecules (ex. water, carbon dioxide)

2. Assembly of these organic molecules into polymers (ex. polypeptides)

Page 47: 1.8

Spontaneous Origin of LifePasteur disproved “spontaneous generation”

Oldest bacterial fossil date back to 1.9 bya

Processes that would have been needed forthe first cells to form include:

1. Chemical reactions to produce simple organic molecules (ex. amino acids) from inorganic

molecules (ex. water, carbon dioxide)

2. Assembly of these organic molecules into polymers (ex. polypeptides)

3. Formation of polymers that can self replicate to allow for the inheritance of characteristics

Page 48: 1.8

Spontaneous Origin of LifePasteur disproved “spontaneous generation”

Oldest bacterial fossil date back to 1.9 bya

Processes that would have been needed forthe first cells to form include:

1. Chemical reactions to produce simple organic molecules (ex. amino acids) from inorganic

molecules (ex. water, carbon dioxide)

2. Assembly of these organic molecules into polymers (ex. polypeptides)

3. Formation of polymers that can self replicate to allow for the inheritance of characteristics

Page 49: 1.8

Spontaneous Origin of LifePasteur disproved “spontaneous generation”

Oldest bacterial fossil date back to 1.9 bya

Processes that would have been needed forthe first cells to form include:

1. Chemical reactions to produce simple organic molecules (ex. amino acids) from inorganic

molecules (ex. water, carbon dioxide)

2. Assembly of these organic molecules into polymers (ex. polypeptides)

3. Formation of polymers that can self replicate to allow for the inheritance of characteristics

4. Packaging of these molecules into membranes with an internal chemistry different from the

Page 50: 1.8

Conditions on early Earth

Page 51: 1.8

Conditions on early Earth

§ Reducing atmosphere

Page 52: 1.8

Conditions on early Earth

§ Reducing atmosphereu water vapor (H2O), CO2, N2, NOx, H2, NH3,

CH4, H2S

Page 53: 1.8

Conditions on early Earth

§ Reducing atmosphereu water vapor (H2O), CO2, N2, NOx, H2, NH3,

CH4, H2S

What’s missingfrom that

atmosphere?

Page 54: 1.8

Conditions on early Earth

§ Reducing atmosphereu water vapor (H2O), CO2, N2, NOx, H2, NH3,

CH4, H2S

u lots of available H & its electron

What’s missingfrom that

atmosphere?

Page 55: 1.8

Conditions on early Earth

§ Reducing atmosphereu water vapor (H2O), CO2, N2, NOx, H2, NH3,

CH4, H2S

u lots of available H & its electronlow O2 =

organic molecules do not breakdown as quickly

What’s missingfrom that

atmosphere?

Page 56: 1.8

Conditions on early Earth

§ Reducing atmosphereu water vapor (H2O), CO2, N2, NOx, H2, NH3,

CH4, H2S

u lots of available H & its electronu no free oxygen low O2 =

organic molecules do not breakdown as quickly

What’s missingfrom that

atmosphere?

Page 57: 1.8

Conditions on early Earth

§ Reducing atmosphereu water vapor (H2O), CO2, N2, NOx, H2, NH3,

CH4, H2S

u lots of available H & its electronu no free oxygen

§ Energy source

low O2 =

organic molecules do not breakdown as quickly

What’s missingfrom that

atmosphere?

Page 58: 1.8

Conditions on early Earth

§ Reducing atmosphereu water vapor (H2O), CO2, N2, NOx, H2, NH3,

CH4, H2S

u lots of available H & its electronu no free oxygen

§ Energy sourceu lightning, UV radiation,

volcanic

low O2 =

organic molecules do not breakdown as quickly

What’s missingfrom that

atmosphere?

Page 59: 1.8

Water vapor

Condensed liquid with complex, organicmolecules

CondenserMixture of gases("primitiveatmosphere")

Heated water("ocean")

Electrodes discharge sparks

(lightning simulation)

Water

Origin of Organic Molecules

CH4

NH3

H2

Page 60: 1.8

Water vapor

Condensed liquid with complex, organicmolecules

CondenserMixture of gases("primitiveatmosphere")

Heated water("ocean")

Electrodes discharge sparks

(lightning simulation)

Water

Origin of Organic Molecules

§ Abiotic synthesisCH4

NH3

H2

Page 61: 1.8

Water vapor

Condensed liquid with complex, organicmolecules

CondenserMixture of gases("primitiveatmosphere")

Heated water("ocean")

Electrodes discharge sparks

(lightning simulation)

Water

Origin of Organic Molecules

§ Abiotic synthesisu 1920

Oparin & Haldane propose reducing atmosphere hypothesis

CH4

NH3

H2

Page 62: 1.8

Water vapor

Condensed liquid with complex, organicmolecules

CondenserMixture of gases("primitiveatmosphere")

Heated water("ocean")

Electrodes discharge sparks

(lightning simulation)

Water

Origin of Organic Molecules

§ Abiotic synthesisu 1920

Oparin & Haldane propose reducing atmosphere hypothesis

u 1953Miller & Urey test hypothesis

CH4

NH3

H2

Page 63: 1.8

Water vapor

Condensed liquid with complex, organicmolecules

CondenserMixture of gases("primitiveatmosphere")

Heated water("ocean")

Electrodes discharge sparks

(lightning simulation)

Water

Origin of Organic Molecules

§ Abiotic synthesisu 1920

Oparin & Haldane propose reducing atmosphere hypothesis

u 1953Miller & Urey test hypothesis§ formed organic

compounds

CH4

NH3

H2

Page 64: 1.8

Water vapor

Condensed liquid with complex, organicmolecules

CondenserMixture of gases("primitiveatmosphere")

Heated water("ocean")

Electrodes discharge sparks

(lightning simulation)

Water

Origin of Organic Molecules

§ Abiotic synthesisu 1920

Oparin & Haldane propose reducing atmosphere hypothesis

u 1953Miller & Urey test hypothesis§ formed organic

compoundswamino acids

CH4

NH3

H2

Page 65: 1.8

Water vapor

Condensed liquid with complex, organicmolecules

CondenserMixture of gases("primitiveatmosphere")

Heated water("ocean")

Electrodes discharge sparks

(lightning simulation)

Water

Origin of Organic Molecules

§ Abiotic synthesisu 1920

Oparin & Haldane propose reducing atmosphere hypothesis

u 1953Miller & Urey test hypothesis§ formed organic

compoundswamino acidswadenine

CH4

NH3

H2

Page 66: 1.8

Stanley Miller

University of Chicago

produced-amino acids

-hydrocarbons-nitrogen bases-other organics

It’s ALIVE!

Page 67: 1.8

Phospholipids

Page 68: 1.8

Phospholipids

§ Hydrophobic or hydrophilic?u fatty acid tails = hydrophobicu PO4 = hydrophilic head

u dual “personality”

Page 69: 1.8

Phospholipids

§ Hydrophobic or hydrophilic?u fatty acid tails = hydrophobicu PO4 = hydrophilic head

u dual “personality”

interaction with H2O is complex & very important!

Page 70: 1.8

Phospholipids

§ Hydrophobic or hydrophilic?u fatty acid tails = hydrophobicu PO4 = hydrophilic head

u dual “personality”

interaction with H2O is complex & very important!

It likes water & also pushes

it away!

Page 71: 1.8

Phospholipids in water

Page 72: 1.8

Phospholipids in water

§ Hydrophilic heads attracted to H2O

Page 73: 1.8

Phospholipids in water

§ Hydrophilic heads attracted to H2O

§ Hydrophobic tails “hide” from H2O

Page 74: 1.8

Phospholipids in water

§ Hydrophilic heads attracted to H2O

§ Hydrophobic tails “hide” from H2Ou can self-assemble into “bubbles”

Page 75: 1.8

Phospholipids in water

§ Hydrophilic heads attracted to H2O

§ Hydrophobic tails “hide” from H2Ou can self-assemble into “bubbles”

§ can also form bilayer

Page 76: 1.8

Phospholipids in water

§ Hydrophilic heads attracted to H2O

§ Hydrophobic tails “hide” from H2Ou can self-assemble into “bubbles”

§ can also form bilayer

bilayer

Page 77: 1.8

Phospholipids in water

§ Hydrophilic heads attracted to H2O

§ Hydrophobic tails “hide” from H2Ou can self-assemble into “bubbles”

§ can also form bilayer

§ early evolutionary stage of cell?

bilayer

Page 78: 1.8

Origin of Cells (Protobionts)§ Bubbles → separate inside from outside → metabolism & reproduction

Page 79: 1.8

Bubbles…Tiny bubbles…

Origin of Cells (Protobionts)§ Bubbles → separate inside from outside → metabolism & reproduction

Page 80: 1.8

Origin of GeneticsDawn of natural selection

Page 81: 1.8

Origin of Genetics

§ RNA is likely first genetic material

Dawn of natural selection

Page 82: 1.8

Origin of Genetics

§ RNA is likely first genetic materialu multi-functional

Dawn of natural selection

Page 83: 1.8

Origin of Genetics

§ RNA is likely first genetic materialu multi-functionalu codes information

Dawn of natural selection

Page 84: 1.8

Origin of Genetics

§ RNA is likely first genetic materialu multi-functionalu codes information

§ self-replicating molecule

Dawn of natural selection

Page 85: 1.8

Origin of Genetics

§ RNA is likely first genetic materialu multi-functionalu codes information

§ self-replicating molecule

§makes inheritance possible

Dawn of natural selection

Page 86: 1.8

Origin of Genetics

§ RNA is likely first genetic materialu multi-functionalu codes information

§ self-replicating molecule

§makes inheritance possible

§ natural selection & evolution

Dawn of natural selection

Page 87: 1.8

Origin of Genetics

§ RNA is likely first genetic materialu multi-functionalu codes information

§ self-replicating molecule

§makes inheritance possible

§ natural selection & evolutionu enzyme functions

Dawn of natural selection

Page 88: 1.8

Origin of Genetics

§ RNA is likely first genetic materialu multi-functionalu codes information

§ self-replicating molecule

§makes inheritance possible

§ natural selection & evolutionu enzyme functionsu transport molecule

Dawn of natural selection

Page 89: 1.8

Origin of Genetics

§ RNA is likely first genetic materialu multi-functionalu codes information

§ self-replicating molecule

§makes inheritance possible

§ natural selection & evolutionu enzyme functionsu transport molecule

§ tRNA & mRNA

Dawn of natural selection

Page 90: 1.8

Key Events in Origin of Life

Page 91: 1.8

Key Events in Origin of Life

§ Key events in evolutionary history of life on Earth

Page 92: 1.8

Key Events in Origin of Life

§ Key events in evolutionary history of life on Earthu life originated

3.5–4.0 bya

Page 93: 1.8

Prokaryotes

§ Prokaryotes dominated life on Earth from 3.5–2.0 bya

Page 94: 1.8

Prokaryotes

§ Prokaryotes dominated life on Earth from 3.5–2.0 bya

Page 95: 1.8

Prokaryotes

§ Prokaryotes dominated life on Earth from 3.5–2.0 bya

3.5 billion year old fossil of bacteria

Page 96: 1.8

Prokaryotes

§ Prokaryotes dominated life on Earth from 3.5–2.0 bya

3.5 billion year old fossil of bacteria modern bacteria

chains of one-celledcyanobacteria

Page 97: 1.8

StromatolitesFossilized mats of prokaryotes resemble modern microbial colonies

Page 98: 1.8

StromatolitesFossilized mats of prokaryotes resemble modern microbial colonies

Page 99: 1.8

StromatolitesFossilized mats of prokaryotes resemble modern microbial colonies

Page 100: 1.8

StromatolitesFossilized mats of prokaryotes resemble modern microbial colonies

Page 101: 1.8

Oxygen atmosphere

Page 102: 1.8

Oxygen atmosphere

Page 103: 1.8

Oxygen atmosphere

§Oxygen begins to accumulate 2.7 bya

Page 104: 1.8

Oxygen atmosphere

§Oxygen begins to accumulate 2.7 byau reducing → oxidizing atmosphere

Page 105: 1.8

Oxygen atmosphere

§Oxygen begins to accumulate 2.7 byau reducing → oxidizing atmosphere

§ evidence in banded iron in rocks = rusting

Page 106: 1.8

Oxygen atmosphere

§Oxygen begins to accumulate 2.7 byau reducing → oxidizing atmosphere

§ evidence in banded iron in rocks = rusting§makes aerobic respiration possible

Page 107: 1.8

Oxygen atmosphere

§Oxygen begins to accumulate 2.7 byau reducing → oxidizing atmosphere

§ evidence in banded iron in rocks = rusting§makes aerobic respiration possible

u photosynthetic

Page 108: 1.8

Oxygen atmosphere

§Oxygen begins to accumulate 2.7 byau reducing → oxidizing atmosphere

§ evidence in banded iron in rocks = rusting§makes aerobic respiration possible

u photosynthetic u algae)

Page 109: 1.8

First Eukaryotes

DNA

cell wall

plasmamembrane

nuclear envelope

plasma membrane

~2 bya

Page 110: 1.8

First Eukaryotes

DNA

cell wall

plasmamembrane

Prokaryoticcell

nuclear envelope

plasma membrane

~2 bya

Page 111: 1.8

First Eukaryotes

infolding of theplasma membrane

DNA

cell wall

plasmamembrane

Prokaryoticcell

nuclear envelope

plasma membrane

~2 bya

Page 112: 1.8

First Eukaryotes

infolding of theplasma membrane

DNA

cell wall

plasmamembrane

Prokaryoticcell

Prokaryotic ancestor of eukaryotic

cells

nuclear envelope

plasma membrane

~2 bya

Page 113: 1.8

First Eukaryotes

infolding of theplasma membrane

DNA

cell wall

plasmamembrane

Prokaryoticcell

Prokaryotic ancestor of eukaryotic

cells

endoplasmicreticulum (ER)

nuclear envelope

plasma membrane

~2 bya

Page 114: 1.8

First Eukaryotes

infolding of theplasma membrane

DNA

cell wall

plasmamembrane

Prokaryoticcell

Prokaryotic ancestor of eukaryotic

cells

endoplasmicreticulum (ER)

nuclear envelope

nucleus

plasma membrane

~2 bya

Page 115: 1.8

First Eukaryotes

infolding of theplasma membrane

DNA

cell wall

plasmamembrane

Prokaryoticcell

Prokaryotic ancestor of eukaryotic

cells

Eukaryoticcell

endoplasmicreticulum (ER)

nuclear envelope

nucleus

plasma membrane

~2 bya

Page 116: 1.8

First Eukaryotes

§ Development of internal membranes

infolding of theplasma membrane

DNA

cell wall

plasmamembrane

Prokaryoticcell

Prokaryotic ancestor of eukaryotic

cells

Eukaryoticcell

endoplasmicreticulum (ER)

nuclear envelope

nucleus

plasma membrane

~2 bya

Page 117: 1.8

First Eukaryotes

§ Development of internal membranesu create internal micro-environments

infolding of theplasma membrane

DNA

cell wall

plasmamembrane

Prokaryoticcell

Prokaryotic ancestor of eukaryotic

cells

Eukaryoticcell

endoplasmicreticulum (ER)

nuclear envelope

nucleus

plasma membrane

~2 bya

Page 118: 1.8

First Eukaryotes

§ Development of internal membranesu create internal micro-environmentsu advantage: specialization = increase efficiency

infolding of theplasma membrane

DNA

cell wall

plasmamembrane

Prokaryoticcell

Prokaryotic ancestor of eukaryotic

cells

Eukaryoticcell

endoplasmicreticulum (ER)

nuclear envelope

nucleus

plasma membrane

~2 bya

Page 119: 1.8

Endosymbiosis

internal membrane system

Endosymbiosis

Page 120: 1.8

Endosymbiosis

internal membrane system

Endosymbiosis

Page 121: 1.8

Endosymbiosis

§ Evolution of eukaryotes

internal membrane system

Endosymbiosis

Page 122: 1.8

Endosymbiosis

§ Evolution of eukaryotes

Ancestral eukaryotic cell

internal membrane system

Endosymbiosis

Page 123: 1.8

Endosymbiosis

§ Evolution of eukaryotesu origin of mitochondria

Ancestral eukaryotic cell

internal membrane system

Endosymbiosis

Page 124: 1.8

Endosymbiosis

§ Evolution of eukaryotesu origin of mitochondria

Ancestral eukaryotic cell

internal membrane system

aerobic bacterium

Endosymbiosis

Page 125: 1.8

Endosymbiosis

§ Evolution of eukaryotesu origin of mitochondriau engulfed aerobic bacteria,

but did not digest them

Ancestral eukaryotic cell

internal membrane system

aerobic bacterium

Endosymbiosis

Page 126: 1.8

Endosymbiosis

§ Evolution of eukaryotesu origin of mitochondriau engulfed aerobic bacteria,

but did not digest themu mutually beneficial relationship

Ancestral eukaryotic cell

internal membrane system

aerobic bacterium

Endosymbiosis

Page 127: 1.8

Endosymbiosis

§ Evolution of eukaryotesu origin of mitochondriau engulfed aerobic bacteria,

but did not digest themu mutually beneficial relationship

Ancestral eukaryotic cell

internal membrane system

aerobic bacterium mitochondrion

Endosymbiosis

Page 128: 1.8

Endosymbiosis

§ Evolution of eukaryotesu origin of mitochondriau engulfed aerobic bacteria,

but did not digest themu mutually beneficial relationship

Ancestral eukaryotic cell

Eukaryotic cellwith mitochondrion

internal membrane system

aerobic bacterium mitochondrion

Endosymbiosis

Page 129: 1.8

mitochondrionEndosymbiosis

Endosymbiosis

Page 130: 1.8

mitochondrionEndosymbiosis

Endosymbiosis

§ Evolution of eukaryotes

Page 131: 1.8

mitochondrionEndosymbiosis

Endosymbiosis

§ Evolution of eukaryotes

Eukaryoticcell with

mitochondrion

Page 132: 1.8

mitochondrionEndosymbiosis

Endosymbiosis

§ Evolution of eukaryotesu origin of chloroplasts

Eukaryoticcell with

mitochondrion

Page 133: 1.8

mitochondrionEndosymbiosis

photosyntheticbacterium

Endosymbiosis

§ Evolution of eukaryotesu origin of chloroplasts

Eukaryoticcell with

mitochondrion

Page 134: 1.8

mitochondrionEndosymbiosis

photosyntheticbacterium

Endosymbiosis

§ Evolution of eukaryotesu origin of chloroplasts u engulfed photosynthetic bacteria,

but did not digest them

Eukaryoticcell with

mitochondrion

Page 135: 1.8

mitochondrionEndosymbiosis

photosyntheticbacterium

Endosymbiosis

§ Evolution of eukaryotesu origin of chloroplasts u engulfed photosynthetic bacteria,

but did not digest themu mutually beneficial relationship

Eukaryoticcell with

mitochondrion

Page 136: 1.8

mitochondrion

chloroplast

Endosymbiosis

photosyntheticbacterium

Endosymbiosis

§ Evolution of eukaryotesu origin of chloroplasts u engulfed photosynthetic bacteria,

but did not digest themu mutually beneficial relationship

Eukaryoticcell with

mitochondrion

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mitochondrion

chloroplast

Eukaryotic cell withchloroplast & mitochondrion

Endosymbiosis

photosyntheticbacterium

Endosymbiosis

§ Evolution of eukaryotesu origin of chloroplasts u engulfed photosynthetic bacteria,

but did not digest themu mutually beneficial relationship

Eukaryoticcell with

mitochondrion

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Theory of Endosymbiosis

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Theory of Endosymbiosis

Lynn Margulis

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§ Evidence

Theory of Endosymbiosis

Lynn Margulis

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§ Evidenceu structural

Theory of Endosymbiosis

Lynn Margulis

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§ Evidenceu structural

§mitochondria & chloroplasts resemble bacterial structure

Theory of Endosymbiosis

Lynn Margulis

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§ Evidenceu structural

§mitochondria & chloroplasts resemble bacterial structure

u genetic

Theory of Endosymbiosis

Lynn Margulis

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§ Evidenceu structural

§mitochondria & chloroplasts resemble bacterial structure

u genetic§mitochondria & chloroplasts

have their own circular DNA, like bacteria

Theory of Endosymbiosis

Lynn Margulis

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§ Evidenceu structural

§mitochondria & chloroplasts resemble bacterial structure

u genetic§mitochondria & chloroplasts

have their own circular DNA, like bacteriau functional

Theory of Endosymbiosis

Lynn Margulis

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§ Evidenceu structural

§mitochondria & chloroplasts resemble bacterial structure

u genetic§mitochondria & chloroplasts

have their own circular DNA, like bacteriau functional

§mitochondria & chloroplasts move freely within the cell

Theory of Endosymbiosis

Lynn Margulis

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§ Evidenceu structural

§mitochondria & chloroplasts resemble bacterial structure

u genetic§mitochondria & chloroplasts

have their own circular DNA, like bacteriau functional

§mitochondria & chloroplasts move freely within the cell

§mitochondria & chloroplasts reproduce independently from the cell

Theory of Endosymbiosis

Lynn Margulis