12.00 12.15 sergio bertoglio - publiceren

REDUCING CRBSI BY USING PREFILLED NORMAL SALINE SOLUTION SYRINGES WHEN FLUSHING AND LOCKING PORT DEVICES IN ADULT CANCER PATIENTS; A SINGLE INSTITUTION PRELIMINARY STUDY  

Disclosure

• No  disclosures  related  to  this  study  

• This  research  was  funded  solely  with  Ins6tu6onal  grants  

ANALYSIS OF PORT FAILURES IST GENOVA 1990-2008

12.5

10.3

7.1 6.6

4,3 3.9 3,4 3.1

0

2

4

6

8

10

12

14

90-95 95-00 00-05 05-08

FAIL

UR

ES

%

INFECTION MECHANICAL FAILURE OTHERS

0,6 0,5 0,4

PREFILLED SALINE SYRINGES RATIONALE

• SIMPLICITY OF USE

• REDUCTION OF MANIPULATION / CONTAMINATION

• SPARING NURSING TIME

• INCREASE PATIENT/NURSES SAFETY

• POSSIBLE REDUCTION OF CRBSI

• POSSIBLE SUBSTANTIAL SAVINGS

RETROSPECTIVE SINGLE INSTITUTION COHORT STUDY OF 801 IMPLANTED PORTS WITH TWO

DIFFERENT MEANS OF FLUSHING AND LOCKING DEVICES

MANUALLY FILLED VS

PREFILLED NORMAL SALINE SYRINGES

SALINE LOCK EVERY 30-DAYS OR AFTER

EVERY ACCES

801 UNSELECTED CONSECUTIVE IMPLANTED PORTS

( September 2009 – august 2011 )

10 ml normal slaine Prefilled Filled Syringes

PFS Group ( 498 patients)

10 ml normal slaine Manually Filled Syringes MFS Group (303 patients)

MINIMUM FOLLOW-UP : 6 MONTHS

MANUALLY FILLLED vs PREFILLED SALYNE SYRINGES

PRIMARY STUDY OUTCOME

CRBS infection incidence requiring port removal

MANUALLY FILLLED vs PREFILLED SALINE SYRINGES

SECONDARY STUDY OUTCOMES *

•  AGE •  GENDER •  PATHOLOGY •  STAGE DISEASE •  ACCES SITE •  BODY SIDE

* Multivariate analysis

MANUALLY FILLED vs PREFILLEDSALINE SYRINGES

Port removal according to the use of MFS or PFS

Port removal for CRBSI - Multivariate analysis

Port removal for any reason – Multivariate analysis

Pathogenic microorganisms responsible for catheter related bloodstream infection according to the use of MFS and PFS

MANUALLY FILLED vs PREFILLED SALINE SYRINGES

Our study provides support that switching from MFS to PFS use during port flushing and locking procedures is a usefull procedure to significantly reduce the incidence rate of CRBSI.

CONCLUSIONS

MANUALLY FILLED vs PREFILLED SALINE SYRINGES

Further controlled studies are advisable to confirm this result and to eventually assess other potential attractive advantages, such as improving nursing work flow, reducing time to prepare flushing syringes.

CONCLUSIONS

THANK YOU VERY MUCH FOR YOUR ATTENTION