and Related Institutions Children's Hospitals National Association of N A C H R I IHI Campaign to Save 100,000 Lives Pediatric Node presents: Preventing Ventilator Associated Pneumonia July 20, 2005 2:00 PM - 3:30 PM (ET) 1:00 PM - 2:30 PM (CT) 12:00 PM - 1:30 PM (MT) 11:00 AM - 12:30PM (PT)
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and Related InstitutionsChildren's HospitalsNational Association of
Phone lines have been muted to reduce background noise
*7 to unmute *6 to mute Please do not put your phone on “hold” 30 minutes for Q & A at the conclusion of
the presentations Session is being recorded and will be
available on CHCA, NACHRI, NICHQ and IHI websites
and Related InstitutionsChildren's HospitalsNational Association of
N A C H R I
IHI Campaign to Save 100,000 Lives
Pediatric Node presents:
Preventing Ventilator Associated Pneumonia
Moderator:Paul Kurtin, MDVice President, Clinical InnovationDirector, Center for Child Health OutcomesChildren’s Hospital and Health Center, San DiegoResearch ProfessorDirector of Maternal and Child Health ProgramSan Diego State University
Launched: December 2004Pediatric Node Launched: January 2005
5 Initiatives Relevant to Pediatrics:– Prevention of Adverse Drug Events using Reconciliation
of Medications (6/15/05)• 82 hospitals; 354 individuals participated in webcast
– Deployment of Rapid Response Teams (6/22/05)• 86 hospitals; 345 individuals participated in webcast
– Prevention of Ventilator-Associated Pneumonia (7/20/05)– Prevention of Central Line Infections (7/27/05)– Prevention of Surgical Site Infections (8/17/05)
• Note time change (12:00N-1:30PM ET) this session only
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IHI Campaign Objectives
Save 100K lives through the introduction of six proven health care improvement interventions over 18 months. (end date 6/14/06 at 9AM).
Enroll a minimum of 1600 hospitals to join IHI in this work. (To date, over 2500 hospitals have signed on to the Campaign).
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Key Campaign Principles
Some is not a number; soon is not a time. Get the “hard count.” Welcome anyone at any level. We do this together.
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IHI Campaign Pediatric Node
Commitment of 3 major pediatric leadership organizations to convene learning collaboratives (Summer Series webcasts) featuring experts in the field.
First ever learning initiative involving the whole pediatric community (FREE).
CHCA, NACHRI, and NICHQ applaud the experts and their respective organizations for their willingness to share their expertise with the whole pediatric community.
CHCA, NACHRI and NICHQ applaud the whole pediatric community for their commitment and hard work in creating high quality healthcare for children.
– Radiographic factors - new or increased infiltrates
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Bacterial causes – “Bad bugs - 1”
Early–Onset Pneumonia– Pathogens:
• Streptococcus pneumoniae
• Haemophilus influenzae
• Staphylococcus aureus
Community-acquired Antibiotic-sensitive
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Late-Onset Pneumonia Pathogens:
– Pseudomonas aeruginosa
– Methicillin resistant Staphylococcus aureus
– Acinetobacter– Enterobacter
Other hospital-acquired Antibiotic-resistance
increasing
Bacterial causes – “Bad bugs - 2”
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Risk Factors for Nosocomial Pneumonia
Number 1 risk factor = endotracheal intubation and mechanical ventilation!
Factors that enhance colonization of the oropharynx &/or stomach:– Administration of antibiotics– Admission to ICU– Underlying chronic lung disease
Conditions favoring aspiration into the respiratory tract or reflux from GI tract:– Supine position *GERD– NGT placement *Comatose– Intubation and self-extubation– Immobilization– Surgery of head/neck/thorax/upper abdomen
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Risk Factors for Nosocomial Pneumonia (continued)
Conditions requiring prolonged use of mechanical ventilatory support – And potential exposure to contaminated respiratory
devices &/or contact with contaminated hands.
Host Factors:– Extremes of age– Malnutrition– Immunosuppression– Underlying condition/disease process
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Implications of VAP
Increased LOS Increased ventilator
days Increased risk of
infection Increased costs Increased morbidity
and mortality
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The Ventilator Bundle
….is a package of evidence-based interventions that, when implemented together for all patients on mechanical ventilation, results in dramatic reduction in the incidence of ventilator-associated pneumonia.
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The Ventilator Bundle
The power of a “bundle” is that it brings together evidence-based practices that individually improve care, but when applied together result in substantially greater improvement.
The science behind the bundle is so well established that it should be considered a “standard of care”.
The focus of measurement is then completion of the entire bundle as a single intervention, rather than completion of its individual components.
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Adult “Ventilator Bundle”
1. Elevation of the head of the bed to between 30 and 45 degrees
2. Daily “Sedation Vacation” and daily assessment of readiness to extubate
3. Peptic ulcer disease prophylaxis
4. Deep vein thrombosis (DVT) prophylaxis
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Adult “Ventilator Bundle”
Preventing VAP – Elevation of the head of bed to 30 and 45 degrees
• Reduction in the risk of aspiration of gastric contents and improved ventilation
Guidelines for Preventing Health-Care--Associated Pneumonia, 2003 Recommendations of CDC and the Healthcare Infection Control Practices Advisory Committee
Modifiable Risk Factors General prophylaxis (Standard of Care)
Effective infection control measures – Staff education– Compliance with hand disinfection– Isolation to reduce cross-infection with multidrug-
resistant (MDR) pathogens
Surveillance of ICU infections – Identify and quantify endemic and new MDR pathogens
– Guide appropriate antimicrobial therapy
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Modifiable Risk factorsIntubation and mechanical ventilation
Avoid intubation and reintubation– Use noninvasive ventilation whenever possible
Use orotracheal/orogastric tubes to prevent nosocomial sinusitis (direct causality not proven)
If cuffed ETTs, inflate them to maintain cuff pressure no greater than 20 cm H2O
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Modifiable Risk factorsIntubation and mechanical ventilation
Avoid neuromuscular blockade
Prevent ventilator circuits condensate from entering ETT or in-line medication nebulizers …. Use closed ETT suctioning and eliminate saline instillation.
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Use of SalineDuring ETT Suctioning
CHB MSICU Practice Guideline
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Modifiable Risk factorsIntubation and mechanical ventilation
Use protocols to improve the use of sedation and to accelerate weaning Avoid constant heavy sedation
Assure adequate nurse staffing and use nurse-implemented protocols to improve infection control practices and reduce duration of mechanical ventilation.
+2 AgitatedDifficulty synchronizing with ventilator
+3 Dangerously agitated, uncooperative
Unsynchronized with ventilator
Modified Motor Activity Assessment ScaleScore as patient’s response to Voice Touch Noxious Stimuli:
(suctioning or nail bed pressure)
From Curley et al. (2001). Critical Care Nursing of Infants and Children
Adapted from Randolph et al. (2002) JAMA, 288: 2561
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Modifiable Risk factors Aspiration, body position, and enteral feeding
Position HOB up 30–45° to prevent aspiration, especially when receiving enteral feeding Continuous rotational therapy and prone positioning
Use enteral nutrition to decrease risk of bacterial translocation
Use post-pyloric feeding in high risk patients (depressed gag reflex, delayed gastric emptying, gastro-esophageal reflux and severe bronchospasm)
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Modifiable Risk factors Modulation of colonization: oral antiseptics and antibiotics
Consider prophylactic systemic antibiotics for 24 hours post emergent intubation (closed head injury)
Modulate oropharyngeal colonization with oral chlorhexidine (need more data) Mouthcare and oral/nasal suction practice guideline (follow
ADA guidelines; “gentle” oral/nasal suction with supplies that are changed daily) Anne Bisch, RN, MSN; St Louis U; [email protected] Munro, RN, PhD; R01NR007652, Oral care intervention
in mechanically ventilated adultsMavilde Pedreira, RN, PhD; Federal University of São Paulo
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Comprehensive Oral Care Program
The Good Shepherd– Retrospective study– VAP rate after practice change showed decrease of 3.4 per 1000 ventilator days– Cost savings approximately $30,000 per VAP
Schleder, B., Stott, K., & Lloyd, R.C. (2002). The effect of a comprehensive oral care protocol on patients at risk for ventilator-associated pneumonias. Journal of Advocate Health Care, 3(1), 1-8.
If needed, stress bleeding prophylaxis with either H2 antagonists or sucralfate (Reduced VAP with sucralfate but slightly higher rate of clinically significant gastric bleeding)
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Give your patient a fast hug (at least) once a day*Jean-Louis Vincent, MD, PhD, FCCM
Fast Hug mnemonic (Feeding, Analgesia, Sedation, Thromboembolic prophylaxis, Head-of-bed elevation, stress Ulcer prevention, and Glucose control)
Identify and check key aspects in the general care of all critically ill patients.
Feeding (bowel regimen) & Family
Analgesia Sedation Thromboembolic
prophylaxis, Tubes & Test (extubation readiness)
Head-of-bed elevation & Honeymoon paralytics
Ulcer prevention (peptic and skin)
Glucose control, GI Prophylaxis and Get OOB
Crit Care Med 2005; 33:1225–1229
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ZAP-VAP initiative at Vanderbilt Together we can make a difference!
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ZAP VAP Team at Children’s Hospital
Ann Johnson - CNS Chris Lynn – RT Trish Campbell - RN Tracy Hann – I.C. Jill Kinch - PCCNP Rick Barr - MD Sandra Dennis Cheryl Burney-Jones Lisa Chumley Shawn Austin Liz Taketani Stormie Eldred
J. K. Deshpande – MD Pat Throop – Qual
Consultant
Our thanks to the
Surgical Intensive Care Team (J. Morris, MD – Chair)
Missy Travis – RN, CIC Tom Talbot – MD, IC Addison May – MD Devin Carr – RN
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Prevention Practices
Basic infection control measures Bundle of treatments to improve patient
outcomes Started on admission Maintained by RNs, RTs, NPs, and MDs
by daily care practices Considered as Standards of Care for
intubated patients
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Ways we will ZAP VAP!
Numero Uno- Wash Hands!
Wash Hands!
Wash Hands!
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Perform Hand Hygiene
Upon reporting for work Before gloving After glove removal Before and after each patient
contact or contact with the patient environment (e.g. bed, table)
After handling contaminated objects
Before handling medications Before eating After using the restroom When leaving the facility
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ZAP VAP
Decreasing the risk of aspiration is key in preventing VAPs.
Elevate HOB > 30 degrees (unless contraindicated)
Monitor gastric residuals q 4 hrs
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ZAP VAP
Aggressive oral care with documentation every 2 hours with Sage Q-Care Oral Cleansing and Suctioning system.
Special pieces include:– A covered Yankauer– A Y-connector to establish a
dedicated oral care line– A suction toothbrush– A suction oral swab– Perox-a-mint mouthwash– Mouth moisturizer
A new suction canister and kit will be obtained q 24 hrs
52
ZAP VAP
Hypopharyngeal suctioning will be performed before suctioning the ETT, before repositioning the ETT, before deflating the cuff, and before repositioning your patient to prevent aspiration of pooled secretions.
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ZAP VAP
Equipment care for patient care:– Use Ballard system or use 2 people (per policy)– Keep saline jet, end of vent circuit, Simms adapter, and
patient’s bag off the bed. Hang them up or place them on a sterile paper (from gloves or gauze).
– Help keep the vent circuit free from accumulated water by draining water away from the patient.
– Change the suction canister and mouth care kit every 24 hours.
and Related InstitutionsChildren's HospitalsNational Association of
N A C H R I
QUESTIONS AND DISCUSSION
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Speaker Bios: Martha A.Q. Curley, RN, PhD, FAAN
Martha A.Q. Curley, RN, PhD, FAAN is Director of Critical Care and Cardiovascular Nursing Research and serves on the faculty of the Program for Patient Safety and Quality at Children’s Hospital, Boston. She holds several academic appointments, including Assistant Clinical Professor of Anesthesia at Harvard Medical School. Dr. Curley serves on numerous hospital, regional and national committees. She is chair of the Nursing Research Council at Children’s Hospital and a member of the Research Steering Committee of the Institute for Nursing Healthcare Leadership. Among her many national committee assignments, she has served as a member of the Committee on Clinical Guidelines and Levels of Care for PICU of the Society of Critical Care Medicine. At the international level, she co-chaired the Scientific Committee for the 4 th World Congress of the World Federation of Pediatric Intensive and Critical Care Societies. As a member of the American Association of Critical Care Nurses (AACN) Certification Board of Directors, she contributed to the development of acute care nurse practitioner standards of care and the agreement to co-sponsor a joint certification for acute care nurse practitioners by AACN and the ANA – the first of its kind in the history of nursing.
Dr. Curley has made substantive contributions in research, teaching and clinical care. Her pioneering studies on the Nursing Mutual Participation Model of Care serve as a foundation for the contemporary role of parents as partners in the care of critically ill children. She developed and published a phase one safety and efficacy study on early and repeated prone positioning in pediatric patients with acute lung injury and is the principal investigator of a large federally funded randomized control trial on prone positioning. Dr. Curley received the American Journal of Nursing Critical Care Book of the Year Award in 1997 and 2002 and was invited to contribute the lead article in Volume 1 of the Journal of the Society of Pediatric Nurses and to serve as guest editor of Volume 1 of Excellence in Nursing Knowledge. She was the primary architect of the Synergy Model, which serves as the blueprint for the CCRN and CCNS certification as well as a framework for nursing care delivery in pediatric and adult hospitals across the country.
Dr. Curley was awarded lifetime membership in the American Association of Critical Care Nurses, the Norma J. Shoemaker Award for excellence in critical care nursing from the Society of Critical Care Medicine and the distinguished alumna award from Yale University. She was inducted into the American Academy of Nursing in 1998.
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Speaker Bios: Jay K. Deshpande, MD, MPH
Jay Deshpande, MD, MPH is Director of the Division of Pediatric Critical Care Medicine and Medical Director of Performance Management and Improvement at Vanderbilt Children’s Hospital. He is Professor of Pediatrics and Anesthesiology and serves as Vice Chair for Clinical Affairs in the Department of Pediatrics and Vice Chair for Faculty Affairs in the Department of Anesthesiology at Vanderbilt University Medical Center (VUMC). Dr. Deshpande is engaged in numerous professional activities, most recently as the Vice President/President Elect of the Society for Pediatric Anesthesia and Chairman of the Education Committee for the Society. He serves on several hospital committees, including the VUMC Executive Safety Committee and the VUMC Executive Quality Council. He is a member of the Board of Directors of The Vanderbilt Medical Group. Dr. Deshpande has served as a mentor to numerous fellows, interns and graduate students. He has authored multiple journal articles and book chapters and is editor of The Pediatric Pain Handbook (1996, 2004 with J.D. Tobias).
Dr. Deshpande currently is Principal Investigator under a Tennessee Emergency Medical Services for Children State Partnership Grant and a Collaborating Investigator on an AHRQ sponsored study on testing improvement strategies in critical care.
Dr. Deshpande earned his medical degree from the University of Tennessee, completed his residency training in pediatrics at LeBonhuer Children’s Medical Center and in anesthesia at the Hospital of the University of Pennsylvania. He completed a fellowship in pediatric anesthesia and critical care at the Children’s Hospital of Philadelphia and was a research fellow in the Department of Anesthesia at the University of Pennsylvania and Laboratory for Experimental Brain Research at the University of Lund, Sweden. He completed a Masters of Public Health, with a focus on quality improvement at Vanderbilt Medical Center. Dr. Deshpande is certified by the Subspecialty Board in Critical Care Medicine.
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Speaker Bios:Paul Kurtin, MD
Paul Kurtin, MD is widely recognized for his work in quality measurement and improvement. In his roles as Vice President for Clinical Innovation and Director of the Center for Child Health Outcomes at Children’s Hospital and Health Center, Dr. Kurtin led the establishment of a culture focused on quality of care and evidence-based medicine. His work was instrumental in the recognition of Children’s Hospital and Health Center eoyj the JCAHO Ernest Codman award in 2002.
Dr. Kurtin is a pioneer in the area of child health care improvement. He was involved in the formation of the Child Health Accountability Initiative (CHAI) and served as its medical director for five years. He is a member of the Executive Committee of the National Advisory Board of the Child and Adolescent Health Measurement Initiative and leads the strategic advisory committee for NICHQ.
A nationally recognized leader in measure development and its use to improve care, Dr. Kurtin has authored numerous articles and publications on quality and outcomes and has served as an expert panelist or consultant to several organizations, including the Institute of Medicine, American Academy of Pediatrics and RAND Corporation. He was a participant in an invitational National Quality Forum Workshop on Children’s Healthcare Quality Measurement and Reporting.
Dr. Kurtin has led numerous community-wide initiatives to assess the needs and improve the health of children in San Diego. He is a member of the San Diego Center for Patient Safety and was named its “Member of the Year” in 2003.
Dr. Kurtin is Research Professor and Director of the Maternal and Child Health Program in the Graduate School of Public Health at San Diego State University. He received his medical degree from the New York University School of Medicine and is board certified in internal medicine and nephrology. He is a fellow of the American College of Pediatrics.