Activate your Get appointment reminders via text or email. www. zoetispetcare.com/reminders 1 CYTOPOINT INJECTION PROVIDES 4 TO 8 WEEKS OF ALLERGIC ITCH RELIEF* CYTOPOINT has been shown to be effective for the treatment of dogs against allergic and atopic dermatitis. *Repeat administration every 4 to 8 weeks as needed in the individual patient. 1 LASTING LOVE DESERVES LASTING REL EF
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Transcript
DAY7
Rate your d
og’s itch
:
Extremely severe
Dog
is scratchin
g, ch
ewin
g, lickin
g, alm
ost contin
uou
sly. It practically n
ever stops, reg
ardless of w
hat else is h
app
enin
g. Q
uality
of life is extremely com
prom
ised for b
oth you
r dog
and
your fam
ily. Itch is affectin
g you
r dog
’s everyday rou
tine, sleep, an
d m
ood.
SevereP
rolong
ed ep
isodes of scratch
ing
and
/or other sym
ptom
s wh
en you
r dog
is awake. Scratch
ing
, licking
, etc, occur at n
igh
t and
also w
hen
eating
, playin
g, or exercisin
g. Th
e contin
ual itch
is causin
g you
r dog
to lose sleep, and
it’s affecting
his/h
er mood
and
activities.
Mod
erateR
egular ep
isodes of scratch
ing
wh
ile awake. Scratchin
g an
d oth
er symp
toms m
ay occur at night an
d w
ake your dog
. But n
o scratching
occurs w
hen eatin
g, p
laying
, exercising
, or bein
g d
istracted. You m
ay notice som
e mood
chang
es and
you feel quality of life can
be b
etter.
Mild
Mod
erately frequ
ent ep
isodes of scratch
ing
and
/or other sym
ptom
s. There m
ay be occasion
al episod
es of scratchin
g at n
igh
t. N
o scratchin
g w
hile sleep
ing
, eating
, playin
g, exercisin
g, or b
eing
distracted
.
Very mild
Occasion
al episod
es of scratchin
g an
d/or oth
er symp
toms. You
r dog
is sligh
tly itchier th
an b
efore the con
dition
beg
an.
Norm
alW
oo hoo! Itch
is not a p
roblem
. 0 20 40 60 80
100
All tradem
arks are the property of Zoetis Services LLC or a related com
CYTOPOINT relieves itch associated with allergic and atopic dermatitis and improves the quality of life for dogs and their owners6
In a study, dogs and their owners noticed signifi cant improvement in allergic itch after the fi rst week of treatment6
Dog owner quality of life more than doubled by day 7 and continued to improve over time6
Dogs experienced improvement in6:
MOOD ACTIVITY SLEEP
References: 1. Data on fi le, Study Report No. C863R-US-12-018, Zoetis Inc. 2. Nuttall T, Uri M, Halliwell R. Canine atopic dermatitis—what have we learned? Vet Rec. 2013;172(8):201-207. doi:10.1136/vr.f1134. 3. Olivry T, DeBoer DJ, Favrot C, et al. Treatment of canine atopic dermatitis: 2010 clinical practice guidelines from the International Task Force on Canine Atopic Dermatitis. Vet Dermatol. 2010;21(3):233-248. doi:10.1111/j.1365-3164.2010.00889.x. 4. Gonzales AJ, Humphrey WR, Messamore JE, et al. Interleukin-31: its role in canine pruritus and naturally occurring canine atopic dermatitis. Vet Dermatol. 2013;24(1):48-53. doi:10.1111/j.136S-3164.2012.01098.x. 5. Marsella R, Sousa CA, Gonzales AJ, et al. Current understanding of the pathophysiologic mechanism of canine atopic dermatitis. J Am Vet Med Assoc. 2012;241(2):194-207. doi:10.2460/javma.241.2.194. 6. Data on fi le, Outcomes Research Study No. 17SORDER, Zoetis Inc.
Activate your
Get appointment reminders via text or email.
www.zoetispetcare.com/reminders
1 CYTOPOINT INJECTION PROVIDES 4 TO 8 WEEKS OF ALLERGIC ITCH RELIEF*
CYTOPOINT has been shown to be effective for the treatment of dogs against allergic and atopic dermatitis.*Repeat administration every 4 to 8 weeks as needed in the individual patient.1
LASTING LOVE DESERVESLASTING
REL EF
Wee
k 1
020406080100
Inje
ctio
n ad
min
iste
red
The Itch Tracker canhelp you monitor your
dog’s allergic itch.
Simply follow the directions to track your dog’s allergic itch.
Then, at your next appointment, take along the chart to discuss
treatment results.
Wee
k 1:
Rat
e yo
ur d
og’s
itch
eve
ry d
ay a
nd
reco
rd it
bas
ed o
n th
e ra
ting
sys
tem
su
pp
lied
.
Wee
ks 2
to 8
: Rat
e yo
ur d
og’s
itch
just
on
ce a
wee
k, o
n th
e sa
me
day
eac
h w
eek.
Pu
t a “d
ot” i
n th
e ap
pro
pria
te c
olu
mn
that
bes
t des
crib
es y
our d
og’s
scra
tch
ing
. Wh
en th
e d
ots
are
con
nec
ted
, you
an
d
you
r vet
erin
aria
n w
ill s
ee th
e p
rog
ress
du
ring
trea
tmen
t an
d h
ow lo
ng
the
inje
ctio
n p
rovi
ded
relie
f.
KEE
P T
RA
CK
OF
ALL
ERG
IC IT
CH
My
dog
’s
qual
ity o
f life
My
qual
ity
of li
fe
Bef
ore
trea
tmen
tW
eek
1W
eek
2W
eek
3W
eek
4W
eek
5W
eek
6W
eek
7W
eek
8
[dog
’s na
me]
Extr
emel
y se
vere
Seve
re
Mod
erat
e
Mild
Very
mild
Nor
mal
do
g
Day
1D
ay 2
Day
3D
ay 4
Day
5D
ay 6
Day
7W
eek
2W
eek
3W
eek
4W
eek
5W
eek
6W
eek
7W
eek
8
___________________________
Itch
Tra
cker
Rat
ing
sca
le: 1
= p
oor q
ual
ity o
f life
; my
dog
is s
ign
ifi ca
ntly
affe
cted
10 =
gre
at q
ual
ity o
f life
; no
imp
act f
rom
itch
Qua
lity
of L
ifeH
ow d
oes
alle
rgic
itch
aff
ect
your
dog
’s q
ualit
y of
life
? C
onsi
der
how
eve
ryd
ay a
ctiv
ities
are
impa
cted
(eg
, sle
ep, m
ood
, act
ivity
, pla
yful
nes
s, in
tera
ctio
ns
with
dog
s/h
uman
s)H
ow d
oes
your
dog
’s a
llerg
ic it
ch a
ffec
t yo
u?
Thin
k ab
out h
ow y
our d
og’s
itch
impa
cts
you
and
you
r fam
ily—
the
emot
ion
al, s
ocia
l, an
d fi
nan
cial
bur
den
of t
he
con
diti
on
(eg
, wak
ing
up
at n
igh
t, n
ot b
ein
g a
ble
to a
tten
d e
ven
ts w
ith y
our d
og, t
he
cost
of i
nef
fect
ive
trea
tmen
ts)
If you notice your dog is constantly licking,chewing, biting, or scratching, it could bedue to allergies. Like people, dogs can be allergic to substances in the environment,such as pollen or mold. These seasonalallergens can cause a dog to become itchyand require treatment when itch “acts up.”But, if the symptoms persist throughout the year, ongoing treatment is usually necessary.
Dogs with persistent itch due to allergiesare often diagnosed with atopic dermatitis, a chronic infl ammatory skin condition affectingup to 10% of dogs worldwide.2 Unfortunately,over time, this condition can get worse andimpact your dog’s quality of life.
WHY IS MY
DOG SO ITCHY?
Your dog’s skin can become red, scaly, and irritated—signs that the normal, healthy skin barrier is damaged.3 Left untreated, damaged skin can become infected and require additional medications like antibiotics to resolve the condition.
Dogs with allergic itch may also lose interest in playing or wake their owners up at night with the constant sounds of licking, chewing, and scratching.4
GOOD NEWS: Your dog can get relief and enjoy
life again—just ask your veterinarian!
CYTOPOINT is a safe, effective, long-lasting treatment for dogs with allergic or atopicdermatitis. CYTOPOINT starts controlling allergic itch within 1 day and reduces scratching, chewing, licking, and biting of the skin for up to 8 weeks.*1 In a study, CYTOPOINT helped damaged skin to begin healing within 7 days.1
*Repeat administration every 4 to 8 weeks as needed in the individual patient.1
WHAT ISCYTOPOINT®?
Dog scratches, damaging skin5
Allergens penetrate and cause an allergic reaction5
Proteins that cause itch are released and attach to nerves in the skin5
CYTOPOINT works where itch begins and breaks the cycle of allergic itch
Itch signals are sent to the brain, triggering the urge to scratch3,5
CYTOPOINT works like your dog’s own immune system to block the signals
that trigger allergic itch.
Wee
k 1
020406080100
Inje
ctio
n ad
min
iste
red
The Itch Tracker canhelp you monitor your
dog’s allergic itch.
Simply follow the directions to track your dog’s allergic itch.
Then, at your next appointment, take along the chart to discuss
treatment results.
Wee
k 1:
Rat
e yo
ur d
og’s
itch
eve
ry d
ay a
nd
reco
rd it
bas
ed o
n th
e ra
ting
sys
tem
su
pp
lied
.
Wee
ks 2
to 8
: Rat
e yo
ur d
og’s
itch
just
on
ce a
wee
k, o
n th
e sa
me
day
eac
h w
eek.
Pu
t a “d
ot” i
n th
e ap
pro
pria
te c
olu
mn
that
bes
t des
crib
es y
our d
og’s
scra
tch
ing
. Wh
en th
e d
ots
are
con
nec
ted
, you
an
d
you
r vet
erin
aria
n w
ill s
ee th
e p
rog
ress
du
ring
trea
tmen
t an
d h
ow lo
ng
the
inje
ctio
n p
rovi
ded
relie
f.
KEE
P T
RA
CK
OF
ALL
ERG
IC IT
CH
My
dog
’s
qual
ity o
f life
My
qual
ity
of li
fe
Bef
ore
trea
tmen
tW
eek
1W
eek
2W
eek
3W
eek
4W
eek
5W
eek
6W
eek
7W
eek
8
[dog
’s na
me]
Extr
emel
y se
vere
Seve
re
Mod
erat
e
Mild
Very
mild
Nor
mal
do
g
Day
1D
ay 2
Day
3D
ay 4
Day
5D
ay 6
Day
7W
eek
2W
eek
3W
eek
4W
eek
5W
eek
6W
eek
7W
eek
8
___________________________
Itch
Tra
cker
Rat
ing
sca
le: 1
= p
oor q
ual
ity o
f life
; my
dog
is s
ign
ifi ca
ntly
affe
cted
10 =
gre
at q
ual
ity o
f life
; no
imp
act f
rom
itch
Qua
lity
of L
ifeH
ow d
oes
alle
rgic
itch
aff
ect
your
dog
’s q
ualit
y of
life
? C
onsi
der
how
eve
ryd
ay a
ctiv
ities
are
impa
cted
(eg
, sle
ep, m
ood
, act
ivity
, pla
yful
nes
s, in
tera
ctio
ns
with
dog
s/h
uman
s)H
ow d
oes
your
dog
’s a
llerg
ic it
ch a
ffec
t yo
u?
Thin
k ab
out h
ow y
our d
og’s
itch
impa
cts
you
and
you
r fam
ily—
the
emot
ion
al, s
ocia
l, an
d fi
nan
cial
bur
den
of t
he
con
diti
on
(eg
, wak
ing
up
at n
igh
t, n
ot b
ein
g a
ble
to a
tten
d e
ven
ts w
ith y
our d
og, t
he
cost
of i
nef
fect
ive
trea
tmen
ts)
If you notice your dog is constantly licking,chewing, biting, or scratching, it could bedue to allergies. Like people, dogs can be allergic to substances in the environment,such as pollen or mold. These seasonalallergens can cause a dog to become itchyand require treatment when itch “acts up.”But, if the symptoms persist throughout the year, ongoing treatment is usually necessary.
Dogs with persistent itch due to allergiesare often diagnosed with atopic dermatitis, a chronic infl ammatory skin condition affectingup to 10% of dogs worldwide.2 Unfortunately,over time, this condition can get worse andimpact your dog’s quality of life.
WHY IS MY
DOG SO ITCHY?SAFE, LONG-LASTING
REL EF.
Safe for dogs of all agesCYTOPOINT is safe to use in dogs of any age. It can also be used in combination with many other commonly used medications, and in dogs with other diseases.6 Because CYTOPOINT is a protein and not a chemical, it is naturally broken down and recycled by the body, so it does not put pressure on the liver and kidneys.
Knowing when it’s time for the next injectionYour veterinarian may schedule a progress exam 4 weeks after the fi rst injection to evaluate how your dog is doing and when he or she will need the next CYTOPOINT injection. However, every dog is different, so monitoring your dog’s allergic itch is important. The attached Itch Tracker canhelp you keep on top of your dog’s allergic itch.
Week 1
0
20
40
60
80
100
Injection administered
The Itch
Tracker canh
elp you m
onitor your
dog
’s allergic itch
.
Simp
ly follow th
e direction
s to track you
r dog
’s allergic itch
. Th
en, at you
r next ap
poin
tmen
t, take alon
g th
e chart to d
iscuss
treatmen
t results.
Week 1: Rate your dog’s itch every day and record it based on the rating system supplied.
Weeks 2 to 8: Rate your dog’s itch just once a week, on the same day each week. Put a “dot” in the appropriate column that best describes your dog’s scratching. When the dots are connected, you and your veterinarian will see the progress during treatment and how long the injection provided relief.
Day 1 Day 2 Day 3 Day 4 Day 5 Day 6 Day 7 Week 2 Week 3 Week 4 Week 5 Week 6 Week 7 Week 8
___________________________ Itch Tracker
Rating scale: 1 = poor quality of life; my dog is signifi cantly affected 10 = great quality of life; no impact from itch
Quality of LifeHow does allergic itch affect your dog’s quality of life? Consider how everyday activities are impacted (eg, sleep, mood, activity, playfulness, interactions with dogs/humans)How does your dog’s allergic itch affect you?Think about how your dog’s itch impacts you and your family—the emotional, social, and fi nancial burden of the condition (eg, waking up at night, not being able to attend events with your dog, the cost of ineffective treatments)
If you n
otice your d
og is con
stantly lickin
g,
chew
ing
, bitin
g, or scratch
ing
, it could
be
du
e to allergies. Like p
eople, d
ogs can
be
allergic to su
bstan
ces in th
e environm
ent,
such
as pollen
or mold
. These season
alallerg
ens can
cause a d
og to b
ecome itchy
and
requ
ire treatmen
t wh
en itch
“acts up.”
Bu
t, if the sym
ptom
s persist th
roug
hou
t the
year, ong
oing
treatmen
t is usu
ally necessary.
Dog
s with
persisten
t itch d
ue to allerg
iesare often
diag
nosed
with
atopic d
ermatitis, a
chron
ic infl am
matory skin
cond
ition affectin
gu
p to 10%
of dog
s world
wid
e. 2 Un
fortun
ately,over tim
e, this con
dition
can g
et worse an
dim
pact you
r dog
’s qu
ality of life.
WH
Y IS MY
DO
G SO
ITC
HY?
DAY 7
Rate your dog’s itch:
Extremely severeDog is scratching, chewing, licking, almost continuously. It practically never stops, regardless of what else is happening. Quality of life is extremely compromised for both your dog and your family. Itch is affecting your dog’s everyday routine, sleep, and mood.
SevereProlonged episodes of scratching and/or other symptoms when your dog is awake. Scratching, licking, etc, occur at night and also when eating, playing, or exercising. The continual itch is causing your dog to lose sleep, and it’s affecting his/her mood and activities.
ModerateRegular episodes of scratching while awake. Scratching and other symptoms may occur at night and wake your dog. But no scratching occurs when eating, playing, exercising, or being distracted. You may notice some mood changes and you feel quality of life can be better.
MildModerately frequent episodes of scratching and/or other symptoms. There may be occasional episodes of scratching at night. No scratching while sleeping, eating, playing, exercising, or being distracted.
Very mildOccasional episodes of scratching and/or other symptoms. Your dog is slightly itchier than before the condition began.
CYTOPOINT relieves itch associated with allergic and atopic dermatitis and improves the quality of life for dogs and their owners6
In a study, dogs and their owners noticed signifi cant improvement in allergic itch after the fi rst week of treatment6
Dog owner quality of life more than doubled by day 7 and continued to improve over time6
Dogs experienced improvement in6:
MOOD ACTIVITY SLEEP
References: 1. Data on fi le, Study Report No. C863R-US-12-018, Zoetis Inc. 2. Nuttall T, Uri M, Halliwell R. Canine atopic dermatitis—what have we learned? Vet Rec. 2013;172(8):201-207. doi:10.1136/vr.f1134. 3. Olivry T, DeBoer DJ, Favrot C, et al. Treatment of canine atopic dermatitis: 2010 clinical practice guidelines from the International Task Force on Canine Atopic Dermatitis. Vet Dermatol. 2010;21(3):233-248. doi:10.1111/j.1365-3164.2010.00889.x. 4. Gonzales AJ, Humphrey WR, Messamore JE, et al. Interleukin-31: its role in canine pruritus and naturally occurring canine atopic dermatitis. Vet Dermatol. 2013;24(1):48-53. doi:10.1111/j.136S-3164.2012.01098.x. 5. Marsella R, Sousa CA, Gonzales AJ, et al. Current understanding of the pathophysiologic mechanism of canine atopic dermatitis. J Am Vet Med Assoc. 2012;241(2):194-207. doi:10.2460/javma.241.2.194. 6. Data on fi le, Outcomes Research Study No. 17SORDER, Zoetis Inc.
Activate your
Get appointment reminders via text or email.
www.zoetispetcare.com/reminders
1 CYTOPOINT INJECTION PROVIDES 4 TO 8 WEEKS OF ALLERGIC ITCH RELIEF*
CYTOPOINT has been shown to be effective for the treatment of dogs against allergic and atopic dermatitis.*Repeat administration every 4 to 8 weeks as needed in the individual patient.1