1 Psychophysiological Assessment of Stress- related Disorders Dragica Kozarić-Kovačić, Tanja Jovanović, Andrea Jambrošić- Sakoman, Slavica Esterajher University Hospital Dubrava, Croatian Ministry of Health Referral Center for the Stress-related Disorders, Regional Center for Psychotrauma COST B27 ENOC Joint WGs Meeting Swansea UK, 16-18 September 2006
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1 Psychophysiological Assessment of Stress-related Disorders Dragica Kozarić-Kovačić, Tanja Jovanović, Andrea Jambrošić-Sakoman, Slavica Esterajher University.
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• Posttraumatic stress disorder (PTSD) and acute stress disorder (ASD) can develop after exposure to traumatic events
• Due to the fact that the diagnosis is based on the patients' self-report of symptoms, a diagnosis of PTSD is difficult to make with certainty, and can be malingered
• There is a need to include more objective assessment techniques in a multimodal approach
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• The psychophysiological reaction to stressful stimuli is under the control of the sympathetic nervous system and is difficult to malinger
• In ASD and PTSD reminders of the traumatic experience induce exaggerated fear and subsequent physiological symptoms.
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Psychophysiology of fear
From Lang, Davis & Öhman (2000), J. Affective Disorders
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Aims of the project
• To see whether PTSD patients have increased psychophysiological arousal to trauma stimuli compared to controls
• To see whether psychophysiological response in ASD will be related to the development of PTSD
• To see whether a lack of association between arousal and PTSD symptoms will be correlated with malingering
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Baseline psychophysiology
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Methods• Participants:
– 15 male subjects with chronic PTSD • (age=39.5±4.7 years)
– 12 male healthy control subjects• (age=41.3±10.7 years)
NA1 VS. ACL5, controls, F(1,11)=17.09, p<0.01; PTSD, F(1,14)=10.40, p<0.01NA1 TO NA7, controls, linear F(1,11)=11.67, p<0.01; PTSD, linear F(1,14)=2.44, ns
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Results: EMG
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EMG: no group differences in startle, no habituation
NA1 VS. ACL5, controls, F(1,11)=5.01, p<0.05; PTSD, F(1,14)=9.50, p<0.01NA1 TO NA7, controls, linear F(1,11)=2.02, ns; PTSD, linear F(1,14)=1.42, ns