1 CALIXARENE BASED CHEMOSENSORS HANNOVER MESSE-2007 16-20 April, 2007 Hannover Iurii MATVIEIEV +38 044 551-1628 +38 050 501-1393 [email protected]National Academy of Sciences of Ukraine Institute of Organic Chemistry Institute of Semiconductor Physics Institute of Macromolecular Chemistry Kiev
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• The technology material presented in this talk is available for licensing or joint product development.
• None of the slides contain any confidential or proprietary information which would prevent patenting the technology.
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Problem Description & Market Need(What is the problem? Or, What is needed in the market? And, How big is the potential market? What is the disease
(if it’s a medical talk)? )
• Variety of sensors provide increased efficiency and ecological safety in many industries. Their use is important factor for improvement of the life quality for modern society.
• Application of traditional methods for monitoring of hazardous substances in variable environment (air, water, waste, etc.) is not often effective and has a range of drawbacks, mainly complicity and long-term exposure.
• The main problem in developing of sensor systems is to supply them with the exceptional selectivity towards a different analytes to be detected in environment.
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Brief technology description
• Array of quartz crystal resonators covered with calixarenecontaining receptors which have different sensitivity towards different volatile organic molecules were developed.
• Due to adsorption of analyte molecules onto sensitive surfaces of sensors frequency of quartz resonators is reducing. This frequency shift is considered as a sensor response.
• Obtained array of sensors responses to pulse of analyte vapor is used for “teaching” system and after that – for recognition of chemical image of analyte by means of special mathematical apparatus for statistical treatment (PCA, Neural Network, etc.).
Working cell volume 9 sm3 Number of channel 8; Frequency drift less 0.5 Hz/ 1h Counter range 0 –16 MHz; Resolution 1 Hz; Time single freq. count. 1s; Time of measuring for recognition less 5 min;Number of recognizing chem. images more 10; Range of analyte concentration 10 – 10000 ppm; Working temperature 20 – 30 Software DOS, Win9X; Power supply 12V/0.4A
CALIXARENE BASED CHEMOSENSOR GAZ-1Main technical characteristics
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Advantages(What is my unique and overwhelming technology advantage?)
• Calixarene based Electronic Nose is used for: monitoring of hazardous pollutants in environment; quality control in food industry and agriculture; quality control of perfumes and beverages.
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Experimental results• Kinetic response strongly depends on interaction between
sensitive layer and analyte molecules. Thus, choosing array for given purpose we consider physical-chemical features of sensitive layers.
Stage of development (clinical tests if medical) and international patents
• The series of calixarene based receptors of ions and neutral molecules were synthesized in the Institute of Organic Chemistry NASU (see www.ioch.kiev.ua/calix )
• The sensitive calixarene based polymer films were prepared in the Institute of Macromolecular Chemistry NASU
• The several chemosensor devices were constructed in the Institute of Semiconductor Physics NASU.
STCU project #3643 “Development of chemosensor materials and equipment for detection toxic substances and pollutants in the environment”