25 Living with Viruses Symposium SYMPOSIUM Symposium 1 Room 1(5F Main Hall) Day 1 October 24 [Tue] 9:00 ~ 11:30 Viral pathogenesis and prevention Chairs: YoshioKoyanagi(KyotoUniversity) KeijiUeda(OsakaUniversity) S1-01 Human herpesvirus 6A/B -pathogenesis and prevention- Yasuko Mori DivisionofClinicalVirology,CenterforInfectiousDiseases,KobeUniversityGraduateSchoolofMedicine,Japan S1-02 Human coronavirus E protein virulence motifs and protection strategies Luis Enjuanes 1) ,Carlos Castaño-Rodriguez 1) ,Javier Gutierrez-Alvarez 1) , Jose M. Honrubia 1) ,Raul Fernandez-Delgado 1) ,Stanley Perlman 2) ,Isabel Sola 1) 1)DepartmentofMolecularandCellBiology.NationalCenterofBiotechnology(CNB-CSIC)CampusUniversidad AutonomaofMadrid.Spain,2)DepartmentofMicrobiology,UniversityofIowa,USA S1-03 A combinatorial CRISPR-Cas9 attack on HIV-1 DNA extinguishes all infectious provirus in infected T cell cultures Ben Berkhout,Gang Wang,Na Zhao,Atze T. Das LaboratoryofExperimentalVirology,UniversityofAmsterdam,theNetherlands S1-04 Many streams do a river make: the multistage process of Bluetongue virus replication and assembly Polly Roy DepartmentofPathogenMolecularBiology,LondonSchoolofHygiene&TropicalMedicine,UK Symposium 2 Room 1(5F Main Hall) Day 2 October 25 [Wed] 9:00 ~ 11:30 Viral propagation and host response Chairs: MakotoTakeda(NationalInstituteofInfectiousDiseases) TatsuoShioda(OsakaUniversity) S2-01 Reverse Genetics Systems for Reoviruses Takeshi Kobayashi DepartmentofVirology,ResearchInstituteforMicrobialDiseases,OsakaUniversity,Japan S2-02 Illuminating the coronavirus replicase: from pathogenicity to molecular function Volker Thiel 1,2) 1)InstituteofVirologyandImmunology,BernandMittelhäusern,Switzerland,2)DepartmentofInfectious DiseasesandPathobiology,UniversityofBern,Bern,Switzerland
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25
Living with VirusesSym
posium
SYMPOSIUM
SYMPOSIUMSymposium 1Room 1(5F Main Hall) Day 1 October 24 [Tue] 9:00~11:30
Viral pathogenesis and preventionChairs:YoshioKoyanagi(KyotoUniversity)
KeijiUeda(OsakaUniversity)
S1-01 Human herpesvirus 6A/B -pathogenesis and prevention-
S3-04 Plant Viruses, Everywhere and Often Mutualistic
Marilyn J. RoossinckCenterforInfectiousDiseaseDynamics,PennsylvaniaStateUniversity,USA
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Living with VirusesSugiura A
ward
SUGIURA AWARD
SUGIURA AWARDRoom 1(5F Main Hall) Day 2 October 25 [Wed] 12:00~13:00Chair:IchiroKurane(NationalInstituteofInfectiousDiseases)
SA-01 Hepatic tropism of hepatitis C virus infectionTakasuke FukuharaDepartmentofMolecularVirology,ResearchInstituteforMicrobialDiseases,OsakaUniversity
SA-02 Functional analysis of host proteins involved in RNA virus replicationSeiya Yamayoshi1,2)
W1-1-01 Evaluation of the vector competency of Haemaphysalis longicornis ticks in transmitting the Japan isolate Thogoto virus to miceMelbourne Talactac1,2,5),Kentaro Yoshii3),Emmanuel Hernandez1,2),Kodai Kusakisako1,2),Kozo Fujisaki4),Masami Mochizuki1),Tetsuya Tanaka1,2)
W1-1-06 Accessibility assessment of the terminal region of influenza A virus genome segments by fluorescence in situ hybridizationFumitaka Momose1,2),Yuko Morikawa1,2)
W1-1-07 A functional vRNA-vRNA interaction important for incorporation of influenza A virus HA segment into virionsSho Miyamoto,Yukiko Muramoto,Keiko Shindo,Jamie Lynn Gilmore,Masahiro Nakano,Takeshi NodaLaboratoryofUltrastructuralVirology,InstituteforFrontierLifeandMedicalSciences,KyotoUniversity
W1-1-08 Co-transport mechanisms of influenza virus HA and NA for the apical plasma membraneTakafumi Kamei1),Fumitaka Momose1,2),Yuko Morikawa1,2)
W1-1-09 Inhibitory effects of an M2 ectodomain-specific monoclonal antibody against different influenza A virus strainsRashid Manzoor1),Nao Eguchi1),Reiko Yoshida1),Hiroichi Ozaki2),Hiroko Miyamoto1),Hirofumi Sawa3),Ayato Takada1)
W1-1-11 Recycling endosome-mediated influenza virus genome transport is required for the assembly of stable viral particlesTakahiro Kuroki1),Kyosuke Nagata2),Atsushi Kawaguchi1,2)
W1-2-05 Investigations on a newly identified host protein required for HIV-1 replication in human T cellsJerry Kwame Ndzinu,Hiroaki Takeuchi,Hideki Saito,Shoji YamaokaDepartmentofMolecularVirology,TokyoMedicalandDentalUniversity
W1-2-06 Mutations in viral capsid modulate IFN-β sensitivity of HIV-1Tahmina Sultana1),Akatsuki Saito1),Hirotaka Ode2),Yasumasa Iwatani2),Emi E Nakayama1),Tatsuo Shioda1)
W1-2-08 Role of fibrocytes on latent HIV-1 infection in ART-treated patientsOsamu Noyori,Shinya SuzuCenterforAIDSResearch,theUniversityofKumamoto
WorkshopRoom 2(5F Small Hall) Day 1 October 24 [Tue] 15:00~15:45
W1-2-09 PP2A-B56δ degradation is crucial for HIV-1 Vif-mediated cell cycle arrestKayoko Nagata,Keisuke Shindo,Akifumi Takaori-KondoDepartmentofHematology&Oncology,GraduateSchoolofMedicine,KyotoUniversity
W1-2-10 Dual infection of two simian foamy virus serotypes in Japanese macaquesAkira Gotoh Hashimoto1),Rokusuke Yoshikawa2),So Nakagawa3),Munehiro Okamoto4),Takayuki Miyazawa1)
W1-2-11 Interaction of PTAP domain of retroviral Gag with TSG101 determines the incorporation of HTLV-1 Env into the virionYosuke Maeda1),Kazuaki Monde1),Hiromi Terasawa1),Yoshiki Honda1),Yuetsu Tanaka2),Keisuke Yusa3),Tomohiro Sawa1)
W1-3-01 A deubiquitinating enzyme USP15 participates in the propagation of HCV through the regulation of lipid metabolismShinji Kusakabe1),Toru Okamoto1),Yukari Sugiyama1),Takasuke Fukuhara1),Kazuhiko Koike2),Yoshiharu Matsuura1)
W1-3-03 Involvement of other miRNA on the propagation of HCV in miR-122-deficient cellsChikako Ono1),Takasuke Fukuhara1),Tomokazu Tamura1),Hiroyuki Mori1),Asuka Sato1),Yuzy Fauzyah1),Toru Okamoto1),Kazuaki Chayama2),Kazuhiko Koike3),Yoshiharu Matsuura1)
W1-3-08 Control of hepatitis B virus replication by microRNAs regulated by the in vivo infectionTsubasa Munakata,Takahiro Sanada,Naoki Yamamoto,Michinori KoharaTokyoMetropolitanInstituteofMedicalScience
WorkshopRoom 3(10F 1003) Day 1 October 24 [Tue] 15:00~15:45
W1-3-09 Novel Crosstalk of Xenobiotic Response with Lipid Biosynthesis Pathway regulates the Host Permissiveness to the Hepatitis C Virus ProductionHirofumi Ohashi1),Syo Nakajima1,2),Sulyi Kim1),Masayoshi Fukasawa3),Ryosuke Suzuki1),Hideki Aizaki1),Fumio Sugawara2),Naoko Ohtani2),Takaji Wakita1),Koichi Watashi1,2)
W1-3-10 Potential Zoonotic Infection of G5 Hepatitis E Virus Produced by Reverse Genetics SystemTiancheng Li1),Sayaka Yoshizaki1),Yuriko Suzaki1),Yasushi Ami1),Yen Hai Doan1),Kei Haga1),Kazuaki Takahashi2),Shunji Mishiro2),Naokazu Takeda3),Takaji Wakita1)
W1-3-11 Critical role of CREBH-dependent transcriptional activation of TGF-β2 by HCV infection in profibrogenic responses in hepatic stellate cellsMasahiko Ito1),Takeshi Chida1,2),Kenji Nakashima1),Yumi Kanegae3),Kazuhito Kawata2),Yoshimasa Kobayashi2),Takafumi Suda2),Tetsuro Suzuki1)
W1-4-02 Engineering of small reporter-tagged Flaviviridae viruses applicable to antiviral screening and in vivo dynamicsTomokazu Tamura1),Takasuke Fukuhara1),Takuro Uchida2),Chikako Ono1),Hiroyuki Mori1),Asuka Sato1),Yuzy Fauzyah1),Toru Okamoto1),Takeshi Kurosu3),Norbert Tautz4),Yoshihiro Sakoda5),Kazuaki Chayama2),Yoshiharu Matsuura1)
W1-4-03 C-terminus region in nsp2 of SARS coronavirus is important for localization to nsp3-nsp4 complex and viral replication.Kengo Kawachi1,2),Yusuke Sakai3),Yoshiharu Matsuura2),Wataru Kamitani1)
W1-4-05 Role of MERS-CoV nonstructural protein 1 in virus replicationKeisuke Nakagawa1),Krishna Narayanan1),Kumari Lokugamage1),Masami Wada1),Ralph Baric2),Shinji Makino1)
W1-4-06 Host Cytosolic Hsp70s play a crucial role in ZIKV propagation.Shuhei Taguwa1),Yeh Ming2),Kelly Rainbolt1),Arabinda Nayak2),Jason Gestwicki3),Raul Andino2),Judith Frydman1)
W1-4-09 BCLXL dependent survivals upon infection with FlavivirusesTatsuya Suzuki,Yukari Sugiyama,Shinji Kusakabe,Makoto Tokunaga,Junki Hirano,Takasuke Fukuhara,Toru Okamoto,Yoshiharu MatsuuraDepartmentofMolecularVirologyResearchInstituteforMicrobialDiseases,OsakaUniversity
W1-4-10 Heat shock protein 90 is required for efficient replication of rubella virusMasafumi Sakata,Hiroshi Katoh,Noriyuki Otsuki,Kiyoko Okamoto,Makoto Takeda,Yoshio MoriDepartmentofVirologyIII,NationalInstituteofInfectiousDiseases
W1-4-11 The characterization of anti-dengue virus cellular factors identified by a gain-of-function screen using interferon-related cDNA libraryYouichi Suzuki,Mami Kotoura,Hong Wu,Takashi Nakano,Kouichi SanoDepartmentofMicrobiologyandInfectionControl,OsakaMedicalCollege
WorkshopRoom 5(10F 1002) Day 1 October 24 [Tue] 13:00~14:00
W1-5-06 Molecular determinants of Ebola virus nucleocapsid assembly and genome packagingHideki EbiharaDepartmentofMolecularMedicine,MayoClinic
W1-5-07 A non-infectious live-cell imaging system reveals the functions of viral proteins for the transport of Ebola virus nucleocapsidsYuki Takamatsu,Larissa Kolesnikova,Stephan BeckerInstituteofVirology,Philipps-UniversityMarburg
W1-5-08 Generation of the infectious bat-derived influenza virus by a reverse genetics methodMasahiro Sato1),Junki Maruyama2),Naganori Nao3),Wakako Furuyama4),Asako Shigeno1),Hiroko Miyamoto1),Rashid Manzoor1),Reiko Yoshida1),Ayato Takada1)
W1-5-09 Analyses of a reassortant virus from substrains of SFTSV YG1 strainSanae Nishio1),Kumiko Yoshimatsu2),Yoshimi Tsuda2),Kenta Shimizu2),Jiro Arikawa2)
W1-6-01 Suppressive cis-acting element in the Epstein-Barr virus LMP1 PromoterMasahiro Yoshida,Yoshitaka Sato,Fumi Goshima,Hiroshi Kimura,Takayuki MurataDepartmentofVirology,NagoyaUniversityGraduateSchoolofMedicine
W1-6-02 Novel varicella-zoster virus latency transcript inhibits viral replicationTomohiko Sadaoka1),Daniel P Depledge2),Werner J. D. Ouwendijk3),Shirley E Braspenning3),Yasuko Mori1),Randall J Cohrs4),Georges M. G. M. Verjans3,5),Judith Breuer2)
W1-6-03 Epstein-Barr viral BART miRNA transcription is upregulated by LMP2A via host transcription factors in epithelial cells.Hyoji Kim,Hisashi Iizasa,Amrizal Muchtar Hadele,Yuichi Kanehiro,Timmy Richardo,Hironori YoshiyamaDepartmentofMicrobiology,ShimaneUniversityFacultyofMedicine,Izumo,Japan
W1-6-04 Experimental strategy to analyze EBV genome variation of Japanese individualsTeru Kanda,Kazufumi Ikuta,Misako YajimaDivisionofMicrobiology,FacultyofMedicine,TohokuMedicalandPharmaceuticalUniversity
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The 65th Annual Meeting of the Japanese Society for Virology
WorkshopRoom 6(10F 1009) Day 1 October 24 [Tue] 14:00~15:00
DNA viruses 2Chairs:KazuhiroKondo(TheJikeiUniversitySchoolofMedicine)
W1-6-06 Cell type-specific regulation of the nuclear egress of herpes simplex virus type1 by phosphorylation of UL51 Ser-184Shinya Oda1,2),Akihisa Kato1,2),Yuhei Maruzuru1),Naoto Koyanagi1,2),Jun Arii1,2),Yasushi Kawaguchi1,2)
W1-6-10 Structural analysis of human herpesvirus 6A immediate early protein 2 C-terminal domainMitsuhiro Nishimura,Aika Wakata,Junjie Wang,Yasuko MoriDivisionofClinicalVirology,CenterforInfectiousDiseases(CID),KobeUniversityGraduateSchoolofMedicine
W1-6-11 Analysis of glycan chains of herpes simplex virus during entry of the host cellsTadahiro Suenaga1),Akihito Sakoguchi1,2),Yasushi Kawaguchi3),Hisashi Arase1,2)
W2-1-02 Antiviral susceptibility of avian influenza A(H7N9) viruses isolated from humansEmi Takashita,Masayuki Shirakura,Seiichiro Fujisaki,Kazuya Nakamura,Tomoko Kuwahara,Noriko Kishida,Shinji Watanabe,Takato OdagiriInfluenzaVirusResearchCenter,NationalInstituteofInfectiousDiseases
W2-1-03 Impact of aging on the pathogenesis of avian influenza A(H7N9) virus infection in non-human primatesSatoshi Fukuyama1),Kiyoko Iwatsuki-Horimoto1),Jason E Shoemaker1,2),Noriko Nakajima3),Maki Kiso1),Yuriko Tomita1),Hiroaki Katsura1),Tadashi Maemura1,4),Tokiko Watanabe1),Yuko Sato3),Tadaki Suzuki3),Hideki Hasegawa3),Yoshihiro Kawaoka1,4,5)
W2-1-05 Characterization of H5N1 influenza virus with HA mutations diversified in human airway epithelial cells as minor variantsYohei Watanabe1,2),Yasuha Arai1,2),Norihito Kawashita3,4),Tomo Daidoji1),Emad M Elgendy1,5),Madiha S Ibrahim5),Junichi Kajikawa1),Hiroaki Hiramatsu6),Tatsuya Takagi4),Kazuo Takahashi7),Tatsuo Shioda2),Yasuo Suzuki6),Takaaki Nakaya1)
W2-1-07 Characterizations of circulating influenza viruses in the 2016/17 season and vaccine viruses for the 2017/18 seasonShinji Watanabe1),Kazuya Nakamura1),Noriko Kishida1),Seiichiro Fujisaki1),Masayuki Shirakura1),Emi Takashita1),Tomoko Kuwahara1),Aya Sato1),Miki Akimoto1),Hideka Miura1),Rie Ogawa1),Hiromi Sugawara1),Kayo Watanabe1),Keiko Mitamura2),Takashi Abe3),Masataka Ichikawa4),Masahiko Yamazaki5),Takato Odagiri1), The Influenza Surveillance Group of Japan6)
W2-1-11 Phylogenetic and phylogeographic analyses of the H5N6 highly pathogenic avian influenza A viruses disseminated in Japan in 2016/2017Nobuhiro Takemae1),Ryota Tsunekuni1,2),Taichiro Tanikawa1,2),Yuko Uchida1,2),Hiroshi Ito3),Kousuke Soda3),Tatsufumi Usui3),Tsuyoshi Yamaguchi3),Junki Mine1,2),Toshihiro Ito3),Takehiko Saito1,2,4)
W2-2-04 Control of HIV-1 by CTLs restricted by an HLA-B*52:01-HLA-C*12:02 protective haplotypeHayato Murakoshi,Takayuki Chikata,Madoka Koyanagi,Lin Zhansong,Tomohiro Akahoshi,Masafumi TakiguchiCenterforAIDSResearch,KumamotoUniversity
WorkshopRoom 2(5F Small Hall) Day 2 October 25 [Wed] 15:00~16:00
W2-2-07 Identification of a detrimental HLA haplotype and the effect of its associated HIV-1 mutations in HIV-1 subtype A/E-infected VietnameseTakayuki Chikata1),Hayato Murakoshi1),Tomohiro Akahoshi1),Nozomi Kuse1),Keiko Sakai1),Masafumi Takiguchi1,2)
W2-2-08 Protective and non-protective MHC class I haplotype-associated viral polymorphisms in simian immunodeficiency virus-infected rhesus macaquesHiroyuki Yamamoto1),Takushi Nomura2),Sayuri Seki1),Midori Nakamura1),Hiroshi Ishii1),Taeko K Naruse3),Akinori Kimura3),Tetsuro Matano1,4)
W2-2-10 Presence of a shared 5'untranslated sequence in ancestral human and mammalian retroviruses and its transduction into feline leukemia virus.Junna Kawasaki1,2),Maki Kawamura3),Jumpei Ito1,4),Kazuo Nishigaki1,3)
W2-3-01 Identification of a hepatitis B virus internalization inhibitor with a novel mode of actionKento Fukano1,2),Senko Tsukuda1),Ryosuke Suzuki1),Hideki Aizaki1),Takaji Wakita1),Yuki Ogasawara2),Koichi Watashi1,3)
W2-3-02 Identification of positive regulators of HBV pregenomic RNA expression that bind to the post-transcriptional element of the viral RNAKenji Nakashima,Masahiko Ito,Suofeng Sun,Tetsuro SuzukiDepartmentofVirologyandParasitology,HamamatsuUniversitySchoolofMedicine
W2-3-03 HCV infection promotes Itch ubiquitin ligase activity via activation of JNK and modulates release of infectious viral particlesLin Deng,Chieko Matsui,Takayuki Abe,Ikuo ShojiDivisionofInfectiousDiseaseControl,CenterforInfectiousDiseases,KobeUniversityGraduateSchoolofMedicine
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Living with VirusesW
orkshop Day 2
W2-3-04 Interaction of hepatitis B virus core protein with microtubules is important for the efficient capsid formation.Masashi Iwamoto1,2),Dawei Cai3),Masaya Sugiyama4),Ryosuke Suzuki1),Hideki Aizaki1),Akihide Ryo5),Naoko Ohtani6),Yasuhito Tanaka7),Masashi Mizokami4),Takaji Wakita1),Haitao Guo3),Koichi Watashi1,2,8)
W2-3-06 Rotavirus non-structural protein NSP6 is not essential for viral replication in cell cultureSaori Fukuda1),Satoshi Komoto1),Yuta Kanai2),Masanori Kugita1),Takahiro Kawagishi2),Tomihiko Ide1),Naoto Ito3,4),Makoto Sugiyama3,4),Yoshiharu Matsuura5),Takeshi Kobayashi2),Koki Taniguchi1)
W2-3-07 Genome-wide analysis of endogenous viral elements in eukaryotic genomesSo Nakagawa1),Mahoko Takahashi Ueda2),Kirill Kryukov1),Tadashi Imanishi1)
W2-3-08 RNA silencing is the determinant of host specificity of mycoreoviruses in the chestnut blight fungusAulia Annisa1),Andika Bagus Ida1),Bradley I Hillman2)
W2-3-09 Nelson Bay Orhoreovirus Cell Attachment protein σC Determines Strain-specific Differences in Viral Infectivity and PathogenesisTakahiro Kawagishi1),Yuta Kanai1),Ryotaro Nouda1),Hideki Tani2),Masayuki Shimojima3),Masayuki Saijo3),Yoshiharu Matsuura4),Takeshi Kobayashi1)
W2-3-10 Discoveries of novel viruses in ticks and fruit bats by using FLDS method and MinION sequencerKeita Matsuno1,2),Masahiro Kajihara3),Syun-Ichi Urayama4),Ryo Nakao5),Miho Hirai4),Yongjin Qiu6),Takuro Nunoura4),Aaron S Mweene7),Bernard M Hang'ombe7),Martin Simuunza7),Masatoshi Okamatsu1),Yoshihiro Sakoda1,2),Hirofumi Sawa2,8),Ayato Takada2,3)
W2-3-11 Genetic characterization of porcine rotaviruses H detected in Japan in recent yearsTohru SuzukiViralDiseaseandEpidemiologyResearchDivision,NationalInstituteofAnimalHealth
W2-3-12 Molecular characterization of rotavirus A isolated from children in 2 cities in Hokkaido, 2010-2016.Mayumi Ono1),Takeshi Tsugawa1),Yusuke Akane2),Yuko Yoto1),Shuji Nakata3),Masatoshi Tatsumi4),Hiroyuki Tsutsumi1)
W2-4-01 Identification and functional analysis of E3 ligases that targeted in DENV NS4BYuki Sameshima,Hirotaka TakahashiProteo-ScienceCenter,EhimeUniversity
W2-4-02 A Mosquito Transmission Model of Zika Virus Infection in mammaliansRyuta Uraki1),Hastings K. Andrew1),Gloria-Soria Andrea2),Powell R. Jeffrey2),Fikrig Erol1,3)
W2-4-03 The Characterization of large and small plaque variants in Zika virus Chiba isolate ZIKV/Hu/S36/Chiba/2016Shigeru Tajima1),Fumihiro Kato1),Eri Nakayama1),Yasuhiro Kawai2),Kenichi Shibasaki1),Masakatsu Taira3),Satoshi Taniguchi1),Takahiro Maeki1),Chang Kweng Lim1),Tomohiko Takasaki4),Masayuki Saijo1)
W2-4-04 The dynamics of disease progression in severe dengueTakeshi Kurosu1),Daisuke Okuzaki2),Kriengsak Limkittikul3),Masayuki Shimojima1),Shuetsu Fukushi1),Shumpei Watanabe1),Masayuki Saijo1)
W2-4-05 Inhibition of autophagy by capsid protein of West Nile virus is involved in accumulation of denatured proteins leading to neurologic diseaseShintaro Kobayashi1),Kentaro Yoshii1),Wallaya Phongphaew2),Memi Muto1),Minato Hirano1),Yasuko Orba2),Hirofumi Sawa2),Hiroaki Kariwa1)
W2-4-07 Development of a Zika virus infection model in common marmosetsToshifumi Imagawa1),Masahiko Ito1),Shuji Takabayashi2),Kazuo Tanaka2),Mami Matsuda3),Ryosuke Suzuki3),Tomohiko Takasaki4),Tetsuro Suzuki1)
W2-4-08 Remarkably high transmission potential of Norovirus among school children during the 2016/17 season in Osaka, JapanRyosuke Omori1,2),Naomi Sakon3),Jun Komano4)
W2-4-10 In-depth characterazation of endogenous flaviviral elements in Aedes mosquito genomesYasutsugu Suzuki1),Lionel Frangeul1),Laura B Dickson2),Herve Blanc1),Yann Verdier3),Joelle Vinh3),Maria-Carla Saleh1)
W2-5-03 Treatment of JAK inhibitor improve the infectivity to tumor and immune response by Newcastle disease virus-infected tumor vaccineMai Ishii1),Takaaki Nakaya2),Katsuro Hagiwara1)
W2-5-04 Analysis of possible influences of nuclear actin in forming the viral factories of Borna disease virus and its crosstalk with Cajal bodiesYuya Hirai1),Akiko Makino2),Hideyuki Okamura1),Keizo Tomonaga2)
W2-5-05 A non-human primate model for severe fever with thrombocytopenia syndrome SFTSMasayuki Shimojima1),Satoshi Taniguchi1),Yasushi Ami2),Noriyo Nagata3),Shuetsu Fukushi1),Takeshi Kurosu1),Shumpei Watanabe1),Hideki Tani1),Aiko Fukuma1),Naoko Iwata-Yoshikawa3),Masayuki Saijo1)
W2-5-06 The role of viral tropism in macrophages in pathogenesis of Ebola virus diseaseYoshimi Tsuda1),Shelly Robertson2),Kimberly Meade-White3),Brandi Williamson2),Jiro Arikawa1),Sonja Best2),Hideki Ebihara4)
The 65th Annual Meeting of the Japanese Society for Virology
W2-5-08 A novel anti-apoptotic role of Sendai virus V protein via its interaction with IRF3Takashi Irie1),Ryoko Kawabata1),Asuka Yoshida2),Isao Okamoto1),Jun Miyake1),Kosuke Oda1),Takemasa Sakaguchi1)
W2-5-09 Relationship between hantavirus infection and chronic kidney disease of unknown aetiology (CKDu) increasing in dry zone area of Sri LankaKumiko Yoshimatsu1),Chandika D Gamage2),Yomani Sarathkumara2),Thiviyaaluxmi Kulendiran3),Nishantha Nanayakkara4),Kenta Shimizu1),Yoshimi Tsuda1),Jiro Arikawa1)
W2-5-10 Molecular biological and evolutionary analyses of an endogenous bornavirus - like nucleoprotein element in miniopterid bat genomesYahiro Mukai1,2),Masayuki Horie1,3),Yuki Kobayashi4),Shohei Kojima1,2),Nao Nagata5),Ken Maeda5),Keizo Tomonaga1,2)
W2-5-11 Molecular phylogenetic analyses of mumps virus on the basis of full-genome sequences by using next-generation sequencer.Minoru Kidokoro1),Keiko Murano1),Naganori Nao1),Manami Negoro2),Makoto Takeda1),Sigeru Suga2)
W2-6-01 Analysis of the magnitude of the effect of HSV-1-interacting cellular chromatin remodeling proteins on viral gene expression and replicationYuka Sato1,2),Yoshikazu Tanaka1),Yasushi Kawaguchi2)
W2-6-02 A host cell membrane protein interacts with HSV-1 gE and promotes viral cell-to-cell spreadMizuki Watanabe1),Jun Arii1),Masayuki Shimojima2),Akihisa Kato1),Yasushi Kawaguchi1)
W2-6-03 HHV-6B envelope glycoprotein complex, gH/gL/gQ1/gQ2 is a key player for virus-induced cell fusionAika Wakata,Satoshi Kanemoto,Anna L Poetranto,Akiko Kawabata,Mitsuhiro Nishimura,Yasuko MoriDivisionofClinicalVirology,CenterforInfectiousDiseases,KobeUniversityGraduateSchoolofMedicine,KobeJapan
W2-6-04 vFLIP is involved in elongated/ spindle cell shape formation in KSHV infected endothelial cells through IKK-epsilon upregulationZunlin Yang,Tomoyuki Honda,Keiji UedaDiv.ofVirology,Dept.ofMicrobiologyandImmunology,OsakaUniversityGraduateSchoolofMedicine
WorkshopRoom 6(10F 1009) Day 2 October 25 [Wed] 15:00~16:00
DNA viruses 5Chairs:HiroshiKimura(NagoyaUniversity)
The 65th Annual Meeting of the Japanese Society for Virology
W2-6-08 APOBEC3C is a responsible enzyme for mitochondrial DNA mutation during Epstein-Barr virus infection in epithelial cellsTimmy Richardo,Yuichi Kanehiro,Sinyatehu Fekadu,Hyoji Kim,Hisashi Iizasa,Hironori YoshiyamaDepartmentofMicrobiology,FacultyofMedicine,ShimaneUniversity
WorkshopRoom 6(10F 1009) Day 2 October 25 [Wed] 16:00~16:45
DNA viruses 6Chairs:HarutakaKatano(NationalInstituteofInfectiousDiseases)
W2-6-09 Human Cytomegalovirus (HCMV) Latency-Associated Protein ORF152 Is Associated With Pathogenesis of Congenital CMV InfectionKazuya Shimada,Nobuyuki Kobayashi,Naomi Oka,Masato Tamai,Mayumi Takahashi,Kazuhiro KondoDepartmentofVirology,TheJikeiUniversity
W2-6-10 Roles of GP33, a guinea pig CMV homolog of G-protein coupled receptor, in cellular signaling and viral growth in vitro and in vivo.Miei Takeda1),Shinji Watanabe1),Kazuma Noguchi1),Takuya Miura1),Akihiro Okumura1),Masashi Sakamoto1),Souichi Yamada2),Tsuyoshi Sugiyama1),Naoki Inoue1)
W2-6-11 Function of the herpes simplex virus 2 protein kinase UL13 in vitro and in vivo is regulated by phosphorylationNaoto Koyanagi1,2),Akihisa Kato1,2),Yuhei Maruzuru1,2),Jun Arii1,2),Yasushi Kawaguchi1,2)
W3-1-02 Quantitative in vivo two-photon microscopy reveals the dynamics of the immune responses to influenza virus infection in the lungI-Hsuan Wang1),Hiroshi Ueki1),Satoshi Fukuyama1),Yoshihiro Kawaoka1,2,3)
W3-1-04 Development of the cell-culture candidate vaccine viruses and quality evaluation method for production of cell-based influenza vaccinesHitoshi Takahashi1),Takao Fujimoto2),Fumiaki Horikoshi2),Tae Uotani2),Mie Okutani2),Itsuki Hamamoto1),Takato Odagiri1),Eri Nobusawa1)
W3-1-05 Enhancement of anti-viral potencies of an intranasal Influenza vaccine-derived broadly neutralizing antibody by IgA polymerizationKaori Sano1,2),Shinji Saito1,3),Tadaki Suzuki1),Akira Ainai1),Osamu Kotani4),Elly Van Riet3),Koshiro Tabata1),Makoto Fujii1),Yoshimasa Takahashi5),Kiyoko Ogawa-Goto6),Hideki Hasegawa1,2)
W3-2-01 The reduced folate carrier is the receptor for Feline Leukemia Virus subgroup EAriko Miyake1),Junna Kawasaki1),Desmond Smith2),Kazuo Nishigaki1)
W3-2-02 CHO cells free from endogenous retrovirus production for manufacturing biopharmaceuticalsYuzhe Yuan1),Yosuke Maeda2),Yoji Sato1),Keisuke Yusa1)
W3-2-03 Systematic Identification of Regulatory Elements Derived from Human Endogenous Retroviruses and Construction of the DatabaseJumpei Ito,Ryota Sugimoto,Shiro Yamada,Hirofumi Nakaoka,Ituro InoueDivisionofHumanGenetics,DepartmentofIntegratedGenetics,NationalInstituteofGenetics
WorkshopRoom 2(5F Small Hall) Day 3 October 26 [Thu] 13:15~14:00
W3-2-04 Non-enzymatic role of HIV-1 Integrase through RT-IN precursor formTakao Masuda,Tatsuro Takahata,Yu-Lun Huang,Atsuhiko Hasegawa,Mari KannagiDepartmentofImmunotherapeutics,GraduateSchoolofMedicalandDentalSciences,TokyoMedicalandDentalUniversity
W3-2-05 Identification and Molecular Characterization of a New HTLV-1 EnhancerMisaki Matsuo1),Paola Miyazato1,2),Hiroo Katsuya1,2),Yuki Inada1,3),Masahito Tokunaga4),Atae Utsunomiya4),Kisato Nosaka5),Hiroyuki Hata6),Yorifumi Satou1,2)
W3-3-02 Prevalence of hepatitis E virus in pigs in JapanKoji Ishii,Tian-Cheng Li,Sayaka Yoshizaki,Takaji WakitaDepartmentofVirologyII,NationalInstituteofInfectiousDiseases
W3-3-03 Phosphorylation of protein kinase R and translational suppression by NS5B protein of hepatitis C virusRyosuke Suzuki1),Mami Matsuda1),Takashi Shimoike1),Koichi Watashi1),Hideki Aizaki1),Takanobu Kato1),Tetsuro Suzuki2),Takaji Wakita1)
The 65th Annual Meeting of the Japanese Society for Virology
W3-3-05 Downregulation of C/EBPα by anti-HCV drug ribavirin leads to the suppression of triglyceride synthesis pathwayShinya Satoh1),Daichi Onomura1),Youki Ueda1),Hiromichi Dansako1),Masao Honda2),Shuichi Kaneko2),Nobuyuki Kato1)
W3-3-06 Establishment of the quantification method for the efficacy of anti-hepatitis virus combination treatmentsKoichi Watashi1,2),Yoshiki Koizumi3),Hirofumi Ohashi1,2),Syo Nakajima1,2),Yasuhito Tanaka4),Takaji Wakita1),Alan S Perelson5),Shingo Iwami6)
W3-4-01 Immunogenicity of the current Japanese encephalitis virus vaccine against recent genotype V strainsTomohiro Ishikawa,Sarah Honjo,Michiaki MasudaDepartmentofMicrobiology,DokkyoMedicalUniversitySchoolofMedicine
W3-4-02 Development of an improved tetravalent dengue vaccine suppressing induction of infection-enhancing antibodyAtsushi Yamanaka1,2),Tatsuo Shioda2,3),Eiji Konishi1)
W3-4-03 Establishment of EV71 vaccine efficacy test using human SCARB2 transgenic miceSatoshi Koike1),Ayumi Imura1),Yui Sudaka1),Ayako Takashino1),Kyosuke Kobayashi1),Ken Fujii1),Hidekazu Nishimura2),Katsumi Mizuta3)
W3-4-04 Defective Interfering RNAs of Poliovirus Inhibit Wild-type Virus Production in Two StepsYuta Shirogane1),Jakub Voznica1),Elsa Rousseau2),Yinghong Xiao1),Igor Rouzine3),Simone Bianco2),Raul Andino1)
W3-4-05 The role of commensal bacteriophage on the activation of innate immune responseHideo Negishi1),Shoji Miki1),Junko Nishio1),Mika Yasui1),Kazuhiko Miyanaga2),Yasunori Tanji2),Tsuyoshi Sekizuka3),Makoto Kuroda3),Akira Ainai4),Hideki Hasegawa4),Yuki Nakajima1),Tadatsugu Taniguchi1)
W3-4-07 Development of an entirely plasmid-based reverse genetics system for rotavirusesYuta Kanai1),Satoshi Komoto2),Takahiro Kawagishi1),Pimfhun Pannacha1),Ryotaro Nouda1),Yoshiharu Matsuura3),Koki Taniguchi2),Takeshi Kobayashi1)
W3-5-01 Neutralizing Antibody Responses against Ebolavirus in Human Survivors of the 2014-2016 West African Ebola epidemicSarah Katharina Fehling1),Camilla Hahn1),Verena Kraehling1),Ruth Thom2),Yper Hall2),Olga Dolnik1),Joseph A. Bore3),Fara Raymond Koundouno3),N Faly Magassouba4),Mandy Kader Konde5),Stephan Guenther6),Stephan Becker1),Miles W. Carroll2),Thomas Strecker1)
W3-5-04 Development of high-throughput screening to find an anti-human parainfluenza virus drug targeting C proteinKosuke Oda1),Takayoshi Okabe2),Yasuyuki Matoba1),Takashi Irie1),Takemasa Sakaguchi1)
W3-5-07 Comparison of transduction efficiency of pseudotyped BoDV vectors with different envelope G proteins from the genus BornavirusMadoka Sakai1,2),Ryo Komorizono1,2),Yumiko Komatu1,3),Sumio Minamiyama4),Makoto Urushitani4),Akiko Makino1),Keizo Tomonaga1,2)
WorkshopRoom 6(10F 1009) Day 3 October 26 [Thu] 12:30~13:30
DNA viruses 7Chairs:NaokiInoue(GifuPharmaceuticalUniversity)
TsugiyaMurayama(HokurikuUniversity)
W3-6-01 Immunization of mice with syngeneic mouse cells expressing glycoproteins of guinea pig CMV to evaluate CMV vaccine antigen candidatesAkihiro Okumura,Masashi Sakamoto,Miku Matuura,Takuya Miura,Kohdai Oguri,Naoki InoueMicrobiologyandImmunology,GifuPharmaceuticalUniversity
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W3-6-02 New vaccine platform based on a viral-vectored prime-boost immunization regimen targeting to malariaKunitaka Yoshida1,2),Mitsuhiro Iyori1),Andrew M. Blagborough3),Ahmed M. Salman4),Katarzyna A. Sala3),Daisuke Yamamoto5),Sumi Biswas4),Masaharu Tokoro2),Adrian V.s. Hill4),Shigeto Yoshida1)
W3-6-03 Characterization of phenylpyrimidine derivatives that inhibit expression of immediate-early genes of cytomegalovirusRyuichi Majima1),Kohhei Yamada1),Toyofumi Yamaguchi2),Naoki Inoue1)
W3-6-04 Clinical Development of Anti-HPV Therapeutics by Small Molecule CompoundMasahiko Ajiro1,2),Hiroyuki Sakai3),Makoto Yamamoto1,4),Hiroshi Onogi4),Takamitsu Hosoya5),Masatoshi Hagiwara1,2)
W3-6-06 Identification of the same polyomavirus species in different African horseshoe bat species is indicative of short range host-switchingMichael J. Carr1),Gabriel Gonzalez2),Michihito Sasaki3),Serena Dool4),Kimihito Ito2),Akihiro Ishii5),Bernard M. Hangombe6),Aaron S. Mweene7),Emma C. Teeling8),William W. Hall1,9),Yasuko Orba3),Hirofumi Sawa1,3,7,9)
P1-O1-03 Conserved secondary structures predicted within the 5' packaging signal region of influenza A virus PB2 segmentA型インフルエンザウイルスPB2セグメントの5’末端パッケージングシグナル領域に予測されたRNA二次構造Yuki Kobayashi1),Yoshiyuki Suzuki2)
P1-O1-05 Influenza A virus-induced cell surface display of GP96 promotes secondary bacterial adherence to epithelial cellsA型インフルエンザウイルス感染に伴い表在化するGP96は化膿レンサ球菌の上皮細胞への付着を亢進させるTomoko Sumitomo,Masanobu Nakata,Masaya Yamaguchi,Shigetada KawabataDepartmentofOralandMolecularMicrobiology,OsakaUniversityGraduateschoolofDentistry
P1-O1-06 INTRACELLULAR LOCALIZATION OF PHOSPHATIDYLINOSITOL (4,5)-BISPHOSPHATE IS ALTERED BY INFLUENZA VIRUS INFECTIONLinh Nguyen Dan Vo,Kyosuke Nagata,Atsushi KawaguchiGraduateSchoolofComprehensiveHumanSciences,UniversityofTsukuba
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The 65th Annual Meeting of the Japanese Society for Virology
P1-O1-07 Substrate specificity of sialic acid species of influenza virus neuraminidaseインフルエンザウイルスNAのシアル酸分子種に対する基質特異性の解析Yuuki Kurebayashi1),Tadanobu Takahashi1),Takashi Yamanaka2),Takashi Suzuki1)
P1-O1-09 Analyses of host serine proteases involved in cleavage of HE protein of the influenza C virusC型インフルエンザウイルスHEタンパクの開裂に関わる宿主プロテアーゼの解析Ko Sato1,2),Hideki Hayashi3),Yoshitaka Shimotai4),Yoko Matsuzaki4),Mutsuo Yamaya5),Seiji Hongo4),Kazuyoshi Kawakami2),Hidekazu Nishimura1)
P1-O1-11 Establishment of immortalized cell clones from human tracheal epithelial cells and their different susceptibility to influenza virusesインフルエンザウイルス感受性が異なるヒト気管上皮由来細胞株群の樹立Junichi Kajikawa1),Tomo Daidoji1),Yohei Watanabe1,2),Yasuha Arai1,2),Ryohei Hirose1,3),Takaaki Nakaya1)
P1-O1-12 Inverse correlation between innate immune responses and pathogenicity of influenza H7N9 virus that is adapted to miceマウスに馴化したインフルエンザA(H7N9)の病原性は自然免疫応答と逆相関するTeruki Miyazaki1),Kimimasa Takahashi2),Makoto Ujike2),Akira Ainai3),Noriyo Nagata3),Hideki Hasegawa3),Takato Odagiri1),Masato Tashiro1),Hideki Asanuma1,3)
P1-O2-03 Novel polymerase gene mutations for human adaptation in clinical isolates of Avian H5N1 influenza virus in Asiaアジアで流行するH5N1鳥インフルエンザウイルスポリメラーゼ遺伝子におけるヒト適応変異の同定Yasuha Arai1,2),Norihito Kawashita3,4),Kozue Hotta5,6),Mai Phuong Vu Hoang7),Khanh Hang Le Nguyen7),Thach Co Nguyen7),Cuong Duc Vuong7),Mai Quynh Le7),Kosuke Soda8),Junichi Kajikawa1),Tomo Daidoji1),Takaaki Nakaya1),Tatsuya Takagi4),Toshihiro Ito8),Futoshi Hasebe5,9),Tatsuo Shioda2),Yohei Watanabe1,2)
P1-O2-08 Development of simple screening method for drug-resistant influenza virus薬剤耐性インフルエンザウイルスの簡易スクリーニング法の開発Chihiro Tamoto,Yuuki Kurebayashi,Tadanobu Takahashi,Takashi SuzukiSchoolofPharmaceuticalSciences,UniversityofShizuoka
P1-O2-09 Rational designs of artificial viral proteins using a novel multiple sequence analysis第四次革新的手法を用いた人工ウイルスタンパク質の創成Naoya Matsuo1),Reiji Higuchi1),Shogo Nakano2),Sohei Ito2),Fumio Seki3),Makoto Takeda3),Hiroaki Tokiwa1)
P1-O2-10 Difference in Replication Capacity of Influenza Viruses in Tottori, Japan, 2009-20152009年から2015年シーズンにおけるインフルエンザウイルス株の多様な増殖能についてAkeno Tsuneki,Kyousuke Kanai,Seiji KageyamaDivisionofVirology,DepartmentofMicrobiologyandImmunology,TottoriUniversityFacultyofMedicine
P1-O2-11 Identification of a Novel Inflammasome Receptor in Respiratory Epithelial Cells in response to Influenza A Virus Infectionインフルエンザウイルス感染に応答した気道上皮細胞特異的な新規インフラマソーム受容体の同定Sangjoon Lee1),Kyosuke Nagata2),Atsushi Kawaguchi1,2)
P1-O3-03 Development of rapid diagnosis for influenza A/H7N9 virus using monoclonal antibodiesH7 HA特異的なモノクローナル抗体を用いたH7N9インフルエンザ迅速診断系の構築Shinji Saito,Hitoshi Takahashi,Shioho Nagata,Takato Odagiri,Tsutomu KageyamaInfluenzaVirusResearchCenter,NationalInstituteofInfectiousDiseases
P1-O3-04 Evaluation of the virus clearance capacity of NIID-MDCK cellsNIID-MDCK細胞の迷入ウイルス排除能の検討Itsuki Hamamoto1),Hitoshi Takahashi1),Katsumi Mizuta2),Ko Sato3),Hidekazu Nishimura3),Takato Odagiri1),Eri Nobusawa1)
P1-O3-06 The mechanism of Inhibition of Influenza Virus Infection by sugar-modified peptide糖修飾ペプチドのインフルエンザウイルス感染阻害メカニズムの解明Yurina Fujiwara,Shunsuke Arami,Teruhiko Matsubara,Toshinori SatoFacultyofScienceandTechnology,KeioUniversity
P1-O3-07 Antiviral Activity of S-033447/S-033188, an Inhibitor of Cap-dependent Endonuclease against Clinically isolated Influenza A and B VirusA及びB型インフルエンザウイルス臨床分離株に対するCap依存的エンドヌクレアーゼ阻害剤S-033188/S-033447の抗ウイルス活性Takeshi Noshi1),Atsuko Yamamoto1),Makoto Kawai2),Ryu Yoshida1),Akihiko Sato1),Takao Shishido1),Akira Naito1)
P1-O3-08 The inhibitory effect of influenza viral infection by hexane extract from the rhizome of Gentiana kurroo Royle collected in Myanmarミャンマー産植物Gentiana kurroo Royle根茎のヘキサン抽出エキスによるインフルエンザウイルス感染阻害活性Masaki Shoji1),So-Yeun Woo2),Mami Tomimoto1),Minami Sugimoto1),Takuya Ito2),Win Nwet Nwet2,3),Hiroyuki Morita2),Takashi Kuzuhara1)
P1-O3-11 KAMPO HERBAL MEDICINES USED FOR INFLUENZA OR RESPIRATORY DISEASES AND THEIR CRUDE DRUGS INHIBIT INFLUENZA REPLICATION.感冒時、インフルエンザ罹患時に使用される漢方薬を構成する生薬のインフルエンザウイルス増殖抑制作用の検討Toshihito Nomura,Takashi Irie,Masaya Fukushi,Kousuke Oda,Takemasa SakaguchiDepartmentofVirology,GraduateSchoolofBiomedical&HealthSciences,HiroshimaUniversity
P1-R1-01 Structural sectors that are contributed to neutralization escape in HIV-1 envelope glycoprotein trimerHIV-1 エンベロープ三量体における中和抗体逃避に寄与する構造セクターMasaru Yokoyama,Hironori SatoPathogenGenomicsCenter,NationalInstituteofInfectiousDiseases
P1-R1-02 Structural Basis of the Interaction between HIV-1 Gag Matrix and IP6 -Toward the Development of IP6 Derivative-Halilibrahim Ciftci1),Hiroshi Tateishi1),Kotaro Koiwai2),Ryoko Koga1),Masami Otsuka1),Mikako Fujita3),Fumiaki Yumoto2),Toshiya Senda2)
P1-R1-03 The role of the C-terminal heptad repeat (CHR) of HIV-1 gp41 in membrane fusionDehua Liu1),Hongyun Wang2),Jiping Song2),Rui Zhang2),Qingling Du2),Yasushi Kawaguchi3,4),Jun-Ichiro Inoue3,5),Zene Matsuda2,3)
P1-R1-05 Comprehensive Deep Sequencing Method for HIV-1 Integration Sites in Human GenomeDeep SequencingによるHIV-1のゲノム組込部位の網羅的解析法Hirotaka Ode1),Ayumi Inoue1),Masakazu Matsuda1),Atsuko Hachiya1),Yoshiyuki Yokomaku1),Yasumasa Iwatani1,2)
P1-R1-10 Absolute Quantification of Integrated HIV-1 DNA in vivo by using Droplet Digital PCRMohammad Saiful Islam1,2),Yohei Seki3),Paola Miyazato1),Benjy Jek Yang Tan1,2),Hirofumi Akari3),Yorifumi Satou1)
P1-R1-11 Role for amino acid residues S149 and I150 of the Gag-CA linker domain in the late HIV-1 replication phaseHIV-1複製後期過程におけるGag-CAリンカー領域内アミノ酸残基S149及びI150の役割Takaaki Koma1),Naoya Doi1),Kei Miyakawa2),Akihide Ryo2),Akio Adachi3),Masako Nomaguchi1)
P1-R1-12 The analysis of HIV-1 genome packaging by comparison of subtype sequences.HIVサブタイプ比較によるゲノムパッケージングに関する解析Jun-Ichi Sakuragi,Sayuri Sakuragi,Tatsuo ShiodaRIMD,OsakaUniversity
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Living with VirusesPoster D
ay 1
PosterPoster Room(10F 1004-7, 1008, Foyer) Day 1 October 24 [Tue] 16:00~17:00
P1-R2-04 Low Vif type of HIV-1 SA1D2prox variants can adaptively mutate to enhance the Vif expression under the strong restrictive conditionHIV-1 SA1D2prox Vif低発現変異体は複製抑制下で適応しVif発現を回復するSakimi Watanabe1),Shoko Nakanishi1),Takaaki Koma2),Naoya Doi2),Akio Adachi3),Masako Nomaguchi2)
P1-R2-06 HTLV-1 HBZ Specifically Intercats with MDFIC and affects its StabilityHTLV-1 HBZタンパク質はTax抑制宿主タンパク質MDFICと相互作用するShuichi Kusano,Masanori IkedaDivisionofPersistentandOncogenicViruses,CenterforChronicViralDiseases,KagoshimaUniversity
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The 65th Annual Meeting of the Japanese Society for Virology
P1-R2-07 Characterization of a G Protein-Coupled Receptor inhibiting HIV-1 replicationHIV-1複製を抑制する新規宿主因子の解析Takeshi Yoshida,Asuka Ueda,Hiroaki Takeuchi,Shoji YamaokaDepartmentofMolecularVirology,TokyoMedicalandDentalUniversity(TMDU)
P1-R2-08 Analysis of structural and functional roles of the HIV-1 Vif PPLP motif regionHIV-1 Vif PPLPモチーフ領域の構造と機能解析Yasumasa Iwatani1,2),Shinya Tsuzuki1,3),Kohei Ito1,3),Akiko Hamano1),Mai Kubota1),Hirotaka Ode1),Tatsuya Matsuoka1,3),Yoshiyuki Yokomaku1),Nobuhisa Watanabe3,4),Atsuko Hachiya1)
P1-R2-10 Two different mechanisms by which MARCH8 inhibits viral infectionKenzo Tokunaga1),Weitong Yao1,2),Takuya Tada1),Yanzhao Zhang1,2),Shoji Yamaoka2),Hideaki Fujita3)
P1-R2-11 Mechanisms of Simian Immunodeficiency Virus infection through Dendritic cells under high-temperature conditions高温条件下での樹状細胞におけるSIV感染拡大機序の検討Takeru Kunimitsu,Kentaro IbukiGraduateSchoolofMedicineKyotoUniversity
P1-R2-12 Evolutionary arms race between APOBEC3 and lentiviruses in felidsネコ科におけるAPOBEC3とレンチウイルスの進化的軍拡競争の実験的検証Hirofumi Aso1),Keisuke Yamamoto1),Izumi Kimura1),Yoriyuki Konno1),Shumpei Nagaoka1),Yusuke Nakano1),Kei Sato1,2),Yoshio Koyanagi1)
P1-R3-01 Establishment of HTLV-1 infected non-human primate model; towards the mechanistic insights into infection and disease developmentHTLV-1感染病態研究に向けたHTLV-1感染霊長類モデルの樹立Emiko Urano1),Yuetsu Tanaka2),Yasuhiro Yasutomi1)
P1-R3-05 Investigation of the potential of feline APOBEC3 to control inter-species transmission of feline immunodeficiency virusAPOBEC3タンパク質によるネコ免疫不全ウイルスの種間伝播制御機構の解析Yoriyuki Konno1),Keisuke Yamamoto1),Shumpei Nagaoka1),Izumi Kimura1),Yusuke Nakano1),Kei Sato1,2),Yoshio Koyanagi1)
P1-R3-07 Molecular epidemiology of HTLV among PLWHIV in the far western part of the Congo basinコンゴ盆地最西部のHIV陽性者に見られたHTLVの分子疫学Eiji Ido1,2),Raphael Taty-Taty3),Steve Ahuka-Mundeke4),Stomy Karhemere4),Keya Sumbu5),Kentaro Ibuki6),Jean-Jacques Muyembe4)
P1-R3-08 The influence of Interferon gamma-inducible restriction factor (IGRF) to placental formationインターフェロンγで誘導される抗レトロウイルス因子が胎盤形成に与える影響Mai Izumida1),Yoshinao Kubo2),Hideki Hayashi3)
P1-R3-10 Phylogenetic analysis of the diversity of HIV-1 subtype B in IndonesiaインドネシアにおけるHIV-1サブタイプBの多様性の系統学的解析Shuhei Ueda1,2,3),Tomohiro Kotaki1,2),Siti Qamariyah Khairunisa3),Adiana Mutamsari Witaningrum3),Dwi Wahyu Indriati3,5),Qushai M Yunifiar3), Nasronudin3,4,6),Masanori Kameoka1,2)
P1-R3-11 Expression level of HIV-2 Vpx/Vpr proteins is regulated by their zinc bindingHIV-2 Vpx/Vpr蛋白質の発現量は亜鉛結合によって制御されているRyoko Koga1),Minami Yamamoto1),Hiroshi Tateishi1),Halil Ibrahim Ciftci1),Masami Otsuka1),Mikako Fujita2)
P1-R3-12 Appearance of drug resistance-associated mutations in HIV type 1 PR and RT derived from infected individuals in Papua, IndonesiaAdiana Mutamsari Witaningrum1),Tomohiro Kotaki2,3),Muhammad Qushai Yunifiarm1),Siti Qamariyah Khairunisa1),Dwi Wahyu Indriati1),Shuhei Ueda1,2,3), Nasronudin1),Masanori Kameoka2,3)
P1-R4-01 Identification of an interferon-inducible RNA binding protein as a restriction factor of HIV-1HIV-1感染を制御する新規RNA結合タンパク質の同定Daichi Yamasoba1),Kei Sato2),Takuya Uehata1),Takashi Mino1),Yoshio Koyanagi2),Osamu Takeuchi1)
P1-R4-02 Evolution of neutralization in a rhesus monkey infected with CCR5 tropic simian / human immunodeficiency virusCCR5指向性サル/ヒト免疫不全ウイルス感染アカゲザル血漿における中和能の進化Ai Himeno,Yuki Ishida,Hiromi Mori,Kanako Matsuura,Minako Kikukawa,Tomoyuki MiuraLab.ofPrimateModel,InstituteforFrontierLifeandMedicalSciences,KyotoUniversity.
P1-R4-03 Characterization of macaque-tropic HIV-1 Long-term Latent infection in Cynomolgus MacaquesYohei Seki1),Akatsuki Saito1),Yorifumi Satou2),Shigeyoshi Harada3),Kazuhisa Yoshimura3),Hirotaka Ode4),Yasumasa Iwatani4),Hiroshi Ishii3),Islam Mohammad Saiful2),Takeshi Yoshida1),Ayaka Washizaki1),Megumi Murata1),Yasuhiro Yasutomi5),Tetsuro Matano3),Tomoyuki Miura6),Hirofumi Akari1,6)
P1-R4-04 Neutralizing antibody induction and changes in viral env sequences in the chronic phase of SIVsmH635FC infectionSIVsmH635FC慢性感染サルにおける中和抗体反応とウイルスenv塩基配列の変化Masato Sano1,2),Takeo Kuwata3),Saori Matsuoka1),Yohei Seki4),Hirofumi Akari4),Tomoyuki Miura5),Tetsuro Matano1,2,3)
P1-R4-05 Development of a new in vitro assay system to evaluate the elimination of HIV-1 latent infectionHIV潜伏感染細胞除去の評価に有用な新規in vitro HIV感染評価系の開発Kenji Maeda1),Kouki Matsuda1),Shin-Ichiro Hattori1),Kiyoto Tsuchiya2),Takuya Kobayakawa3),Nami Ohashi3),Wataru Nomura3),Shigeyoshi Harada4),Yorifumi Satou5),Kazuhisa Yoshimura4),Hirokazu Tamamura3),Hiroaki Mitsuya1,6)
P1-R4-07 Evaluation of antiviral effects and cytotoxity of silver nano particles (AgNPs) with different dispersion stabilizer異なる分散剤共存下におけるナノ化銀の抗ウイルス能及び細胞障害性の評価Ken Katogi1,2),Takeru Kunimitsu2),Sho Sekine2),Haruka Yokoyama2),Mihiro Shibata2),Moe Jinno2),Kentaro Ibuki2)
P1-R4-08 Use of dried blood spot specimens for in-house HIV drug resistance genotyping assay among young children in Thailand.Siriphan Saengaroon1),Ruangchai Loket1),Wiroj Puangtabtim2),Rachaneekorn Jaisue2),Nattapong Klamklai1),Ratrawee Boonmuang1),Korrakot Prommajan1),Somchai Sangkitporn1),Archawin Rojanawiwat2)
P1-R4-09 Fluorescence and luminescence assays for screening novel small chemical compounds that inhibit NF-κB activation in adult T-cell leukemia成人T細胞白血病のNF-κB活性化を阻害する低分子化合物の蛍光・発光アッセイによる探索Naoyoshi Maeda1),Natsuki Miyazaki1),Satoko Otsuguro1),Makoto Yoshimitsu2),Hiromitsu Hara3),Katsumi Maenaka1,4)
P1-R4-12 In vitro and in vivo antitumor activity of Tamoxifen in the human T-cell leukemia virus type I-infected cellsタモキシフェンによるHTLV-1感染細胞増殖抑制Takeo Ohsugi1),Yusuke Nagano1),Yuzo Tanaka1),Tomoki Kozuka1),Rie Nishii1),Makoto Yamagishi2),Toshiki Watanabe3)
P1-R4-13 CRISPR/Cas9 system targeting HIV-1 regulatory genes tat and rev inhibits viral replication in persistently- and latently-infected T cellsYoudiil Ophinni1),Mari Inoue2),Masanori Kameoka1,2)
P1-H1-01 Capsids of hepatitis E virus particles are individually covered by lipid membranes膜に覆われたE型肝炎ウイルス粒子は個々のキャプシドが脂質膜に覆われているShigeo Nagashima,Masaharu Takahashi,Tominari Kobayashi,Gis Tang,Putu Prathiwi Primadharsini,Takashi Nishiyama,Tsutomu Nishizawa,Hiroaki OkamotoDivisionofVirology,DepartmentofInfectionandImmunity,JichiMedicalUniversitySchoolofMedicine
P1-H1-02 DMSO enhances HBV infection into the hepatocytes differentiated from iPS cellsDMSOはiPS細胞より分化誘導した肝細胞へのHBV感染を高めるKazuyuki Kuroki,Hitomi ShimuraCancerResearchInstitute,KanazawaUniversity
P1-H1-03 Analysis of two function-unknown open reading frames (ORF3 and ORF4) of rat hepatitis E virus (HEV) genomeラットE型肝炎ウイルスゲノムの2つの機能不明ORFs(ORF3とORF4)の解析Jisi Tang,Masaharu Takahashi,Tominari Kobayashi,Shigeo Nagashima,Takashi Nishiyama,Hiroshi Ohnishi,Tsutomu Nishizawa,Hiroaki OkamotoDivisionofVirology,DepartmentofInfectionandImmunity,JichiMedicalUniversitySchoolofMedicine
P1-H1-04 Ribonucleotide reductase M2 promotes hepatitis C virus RNA replication by enhancing the stability of the NS5B proteinBouchra Kitab1),Michinori Kohara2),Kyoko Tsukiyama-Kohara1)
P1-H1-05 Analysis of HBV life cycle in the HepG2 expressing human NTCP cell lineRetno Rahayu1),Eriko Ohsaki1),Tomoyuki Honda1),Toru Okamoto2),Koichi Watashi3),Keiji Ueda1)
P1-H1-06 Supporting evidence that the ER/ERGIC is the main budding site for the Hepatitis B virus virionB型肝炎ウイルスビリオンの主な出芽部位はER/ERGICであることを支持する補強証拠Ming Chen1),Lin Deng2),Chie Aoki-Utsubo3),Kouichi Watashi4),Takaji Wakita4),Hak Hotta1,3)
P1-H1-09 Inhibition of the release of virus-like particles by HBV S protein but not of HBV by tetherin/CD317/BST2tetherin/CD317/BST2によるS蛋白質によるウイルス様粒子の放出阻害Toshiki Matsubara1),Reiko Yoshimoto1),Ryoko Kawabata1),Hiromi Abe-Chayama2),Masaya Fukushi1),Kosuke Oda1),Takashi Irie1),Kazuaki Chayama2),Takemasa Sakaguchi1)
P1-H2-01 Establishment of hepatitis B and C virus co-infection cell lineB型およびC型肝炎ウイルス共感染培養細胞系の開発Teruhime Otoguro,Tomohisa Tanaka,Hirotake Kasai,Atsuya Yamashita,Kohji MoriishiDepartmentofMicrobiology,Facultyofmedicine,UniversityofYamanashi
P1-H2-02 Development of HBV infection system using human immortalized hepatocyte NKNT-3 cellsヒト不死化肝NKNT-3細胞を用いたHBV感染システムの開発Hiromichi Dansako1),Hirotaka Imai1),Youki Ueda1),Shinya Satoh1),Kunitada Shimotohno2),Nobuyuki Kato1)
P1-H2-06 Establishment of optimal culture system for chronic HBV infectionHBV持続感染に最適な培養系の構築Naoki Yamamoto,Tsubasa Munakata,Michinori KoharaTokyoMetropolitanInstituteofMedicalScience
P1-H2-07 Identification of interferon stimulated genes regulating the function and subcellular localization of HBV core proteinインターフェロン誘導性因子によるHBVコア蛋白質の機能制御機構の解明Mina Dairaku,Kei Miyakawa,Satoko Matsunaga,Akihide RyoDepartmentofMicrobiology,YokohamaCityUniversityGraduateSchoolofMedicine
P1-H2-08 Role of phosphatases in the regulation of HBV assemblyHBVコア蛋白質の脱リン酸化を司る宿主因子の探索Kei Miyakawa,Mina Dairaku,Satoko Matsunaga,Akihide RyoDepartmentofMicrobiology,YokohamaCityUniversityGraduateSchoolofMedicine
P1-H2-09 Human hepatic stellate cells are permissive for hepatitis C virus infection/replication and play important roles in fibrosisXin Zheng1),Takuma Zaitsu1,2),Haruyo Aoyagi1),Mami Matsuda1),Noriyuki Watanabe1),Akira Fujimoto1),Koichi Watashi1),Ryosuke Suzuki1),Takasuke Fukuhara3),Yoshiharu Matsuura3),Shizuko Ichinose4),Kenjiro Wake5),Tetsuro Suzuki6),Hiroko Iijima7),Hiroshi Yokoyama8),Takahiro Masaki8),Tomokazu Matsuura8),Koji Tamura2),Takaji Wakita1),Hideki Aizaki1)
P1-H2-11 Analysis of the states of HCV with 17% ethanol-treatment in Cohn ethanol methodCohn エタノール法における17%エタノール処理によるHCVの変化の解析Takashi Shimoike1),Kiyoko Nojima1),Takaji Wakita1),Isao Hamaguchi1),Yoshiaki Okada2)
The 65th Annual Meeting of the Japanese Society for Virology
P1-H2-12 Analysis of HCV in the fractions with Cohn ethanol method in a laboratory scale実験室レベルのCohnエタノール法による血液製剤の各画分中のHCVの解析Kiyoko Nojima1),Takashi Shimoike1),Takaji Wakita1),Isao Hamaguchi1),Yoshiaki Okada2)
P1-H3-02 Hepatitis C virus NS3/4A protease cleaves SGP20 and promotes lipid droplet growthC型肝炎ウイルスNS3/4AプロテアーゼはSPG20を切断し脂肪滴肥大化を促進するChieko Matsui,Nanae Minami,Lin Deng,Takayuki Abe,Ikuo ShojiDivisionofInfectiousDiseaseControl,CenterforInfectiousDiseases,KobeUniversityGraduateSchoolofMedicine
P1-H3-03 Hepatocytes Retaining the Large Hepatitis B Surface Antigen (LHBs) are Susceptible to the Cytotoxic Effect of Type I InterferonsMasanori Isogawa1),Ian Baudi1),Keigo Kawashima1,2),Yasuhito Tanaka1)
P1-H3-05 Comprehensive identification of viruses in pediatric patients with acute liver failure using next-generation sequencing次世代シーケンサーを用いた小児急性肝不全患者からの網羅的ウイルス検出Takako Suzuki,Jun-Ichi Kawada,Kazuhiro Horiba,Suguru Takeuchi,Yuka Torii,Yoshinori ItoDepartmentsofPediatrics,NagoyaUniversityGraduateSchoolofMedicine
P1-H3-06 Quantification and characterization of HEV capsid antigen in plasma of HEV-infected blood donors.HEV陽性献血者におけるHEV抗原の定量およびHEVの性状解析Rieko Sobata1),Chieko Matsumoto1),Takashi Owada1),Hidekatsu Sakata2),Keiji Matsubayashi1),Tadashi Nagai1),Masahiro Satake1)
P1-H3-07 Identification and characterization of a novel genotype 3 hepatitis E virus strain in pigs imported from Denmark to Japanデンマーク由来輸入ブタからの新規3型E型肝炎ウイルス株の同定と解析Putu Prathiwi Primadharsini1),Masao Miyake2),Satoshi Kunita3),Tsutomu Nishizawa1),Masaharu Takahashi1),Shigeo Nagashima1),Jisi Tang1),Hiroshi Ohnishi1),Tominari Kobayashi1),Takashi Nishiyama1),Hiroaki Okamoto1)
P1-H3-08 Induction of neutralization E2 antibody by immunization of recombinant E2 proteins組換えE2タンパク質による中和抗体誘導効果Noriyuki Watanabe,Tomoko Date,Hussein Aly,Hideki Aizaki,Takaji WakitaDepartmentofVirologyII,NationalInstituteofInfectiousDiseases
P1-H3-09 Identification of new amino acid substitutions contributing to DAA-resistance, using HCV reporter assay systemsHCVレポーターアッセイ系によるDAA抵抗性に関与する新規アミノ酸置換の同定Youki Ueda1),Hiromichi Dansako1),Shinya Satoh1),Masanori Ikeda2),Nobuyuki Kato1)
P1-H3-10 Inhibitory effects of metachromin A on hepatitis B virus production via impairment of the viral promoter activityMetachromin AによるHBVプロモーター活性減弱とウイルス産生阻害効果Atsuya Yamashita,Tomohisa Tanaka,Teruhime Otoguro,Hirotake Kasai,Kohji MoriishiDepartmentofMicrobiology,DivisionofMedicalSciences,FacultyofMedicine,GraduateFacultyofInterdisciplinaryResearch,UniversityofYamanashi
P1-H3-11 Resistant acquisition mechanism for anti-HCV drug candidates, N-89 and its derivative N-251抗HCV薬候補N-89とその誘導体N-251に対する抵抗性獲得機序Weilin Gu,Youki Ueda,Shinya Satoh,Hiromichi Dansako,Nobuyuki KatoDepartmentofTumorVirology,OkayamaUniversityGraduateSchoolofMedicine,Dentistry,andPharmaceuticalSciences.
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The 65th Annual Meeting of the Japanese Society for Virology
P1-H3-13 Development of a safe and rapid assay for measuring Hepatitis B virus reverse transcriptionHBVの逆転写を安全かつ極めて短時間に評価するアッセイ法の開発Kenji Ogawa1,2),Yasue Ichikawa1),Minoru Yoshida1,2)
P1-H3-14 Inhibition mechanism of hit compound by drug screening targeting HBV RTHBV RTを標的とした薬剤スクリーニングによるヒット化合物の阻害メカニズムの検討Eriko Ohsaki,Tomoyuki Honda,Keiji UedaVirology,DepartmentofMicrobiologyandImmunology,OsakaUniversityGraduateSchoolofMedicine
P1-H3-15 Guanfacine, a sympatholytic drug, exhibits anti-hepatitis C virus activity.交感神経遮断薬であるグアンファシンは抗HCV活性を示すMidori Takeda1),Natsue Maezono1),Mina Kamitakahara1),Takaji Wakita2),Nobuyuki Kato3),Masanori Ikeda1)
P1-H3-19 The time required to eradicate a covalently closed circular DNA pool in patients under entecavir or lamivudine monotherapies in Hepatitis B infectionAlexey MartyushevDepartmentofBiology,KyushuUniversity
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PosterPoster Room(10F 1004-7, 1008, Foyer) Day 1 October 24 [Tue] 16:00~17:00
P1-DRO-03 Analysis of genome packaging mechanism of Nelson Bay Orthoreovirusネルソンベイオルソレオウイルスにおける分節ゲノムパッケージング機構の解明Misa Onishi1),Yuta Kanai1),Takahiro Kawagishi1),Ryotaro Nouda1),Pimfhun Pannacha1),Masayuki Shimojima2),Masayuki Saijo2),Yoshiharu Matsuura3),Takeshi Kobayashi1)
P1-DRO-04 Functional Analysis of Nelson Bay Orthoreovirus p17 Proteinコウモリを自然宿主とするNelson Bay Orthoreovirusのp17タンパク質の機能解析Ryotaro Nouda1),Takahiro Kawagishi1),Yuta Kanai1),Masayuki Shimojima3),Masayuki Saijo3),Yoshiharu Matsuura2),Takeshi Kobayashi1)
P1-DRO-05 Clinical investigation of 6 cases of MERS complicated with rotavirus gastroenteritisSatoshi Hirakawa,Ikumi Yabuki,Emiko Hoshino,Nodoka Sakurai,Yuki Kuroiwa,Shigeto Fuse,Toshihiko MoriDepartmentofPediatrics,SapporoMedicalcenterNTTEC
P1-DRO-06 Genetic analysis targeting complete ORF of epizootic hemorrhagic disease virus serotype 6 detected from cattle in Hyogo, Japan, 20152015年に兵庫県でウシから検出された流行性出血病ウイルス血清型6のORF全長を対象とした遺伝子解析Hiroaki Shirafuji,Tohru YanaseSubtropicalDiseaseControlUnit,DivisionofTransboundaryAnimalDiseases,NationalInstituteofAnimalHealth(NIAH),NationalAgricultureandFoodResearchOrganization(NARO)
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P1-DRO-07 Molecular epidemiology of rotavirus detected in a pediatric outpatient clinic in Gunma Prefecture, 2015-20162015-2016年の群馬県一小児科外来におけるロタウイルス感染症の疫学Shoko Okitsu1,2),Aksara Thongprachum2),Pattara Khamrin3),Toshiyuki Hikita4),Sayaka Takanashi1),Satoshi Hayakawa2),Hiroshi Ushijima1,2)
P1-DRO-08 High prevalence of G3P[8] rotavirus strains with a short electropherotype in acute gastroenteritis cases in ThailandRatana Tacharoenmuang1),Sompong Upachai1),Ratigorn Guntapon1),Satoshi Komoto2),Phakapun Singchai1),Busarawan Sriwattana3),Kazushi Motomura4,6),Tomihiko Ide2),Tetsushi Yoshikawa5),Naokazu Takeda6),Somchai Sangkitporn1),Koki Taniguchi1)
P1-DRO-10 Isolation of a novel coltivirus from the cerebral fluid of a dead raccoon dog死亡タヌキの脳脊髄液から新規コルチウイルスの分離Shohei Minami1),Shiori Aoki1),Nao Nagata1),Kenzo Yonemitsu1),Keita Noguchi1),Ryusei Kuwata1),Hiroshi Shimoda1),Miki Yoshizawa2),Haruna Inoue2),Shun Saito2),Takashi Watabe2),Ryusuke Fujita3),Hiroko Ejiri3),Haruhiko Isawa3),Kyoko Sawabe3),Shigeru Morikawa4),Ken Maeda1)
P1-DRO-11 Full genomic analysis of a human G9P[23] rotavirus strain from a child with diarrhoea in Thailand.タイで小児の下痢便から検出されたロタウイルスG9P[23]株ゲノムの全塩基配列の解析Tomihiko Ide1),Satoshi Komoto1),Ratana Tacharoenmuang2),Ratigorn Guntapong2),Phakapun Sinchai2),Sompong Upachai2),Saori Fukuda1),Tetsushi Yoshikawa3),Piyanit Tharmaphornpilas4),Somchai Sangkitporn2),Koki Taniguchi1)
P1-DRO-12 High susceptibility of Sortilin-deficient cells to prion infectionSortilin欠損細胞はプリオン感染に対して高感受性を示すKeiji Uchiyama,Tomohiro Toko,Suehiro SakaguchiInstituteforAdvancedMedicalSciences,TokushimaUniversity
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P1-DRO-13 Identification and investigation of a novel anti-prion compound新規抗プリオン化合物の同定とその有効性の検証Keiji Uchiyama,Suehiro SakaguchiInstituteforAdvancedMedicalSciences,TokushimaUniversity
P1-DRO-14 Analysis of the effect of hydrogen peroxide gas sterilizer on prion agent過酸化水素ガス滅菌器による処理がプリオン病原体に与える影響の解析Akikazu Sakudo1),Yasushi Hanada2),Kazuhiro Miwa2)
P1-DRO-16 Comprehensive detection of antiviral antibodies in human serum using a protein active arrayProtein Active Arrayを用いたヒト血清中に含まれる抗ウイルス抗体の網羅的検出Satoko Matsunaga1),Yuki Matsushima2),Ryo Morishita1,3),Hirokazu Kimura4),Akihide Ryo1)
The 65th Annual Meeting of the Japanese Society for Virology
POSTER DAY 2(October 25[Wed])
POSTER DAY 2(October 25[Wed])PosterPoster Room(10F 1004-7, 1008, Foyer) Day 2 October 25 [Wed] 17:00~18:00
DNA viruses 1Chair:JunArii(theUniversityofTokyo)
P2-D1-01 Guinea pig CMV infection was enhanced in epithelial cells expressing GP131 and GP133, components of the non-fibroblast tropism determinant細胞指向性に関与するGP131/GP133の発現による上皮細胞へのモルモットサイトメガロウイルス感染の亢進Miku Matsuura1),Takuya Miura1),Reina Makino1),Souichi Yamada2),Naoki Inoue1)
P2-D1-02 Epstein-Barr Virus BKRF4 Gene Product is Required for Efficient Progeny ProductionH. M. Abdullah Al Masud,Takahiro Watanabe,Masahiro Yoshida,Yoshitaka Sato,Fumi Goshima,Hiroshi Kimura,Takayuki MurataDepartmentofVirology,NagoyaUniversityGraduateSchoolofMedicine
P2-D1-04 Virus reactivation induced by chemicals in the EBV DNA detected cell lines;Application for the standardized assessment.ウイルスDNA検出検査でEBV陽性を示す細胞株を用いた薬剤刺激によるウイルスの再活性化―再活性化検出系構築の試みSetsuko Shioda1),Midori Ozawa1),Kohei Kawakami1),Ken Watanabe2),Norio Shimizu2),Arihiro Kohara1)
P2-D1-06 Study of EBV-reactivation by epigenetic modification in EBV-positive cellsEBV潜伏感染細胞のエピジェネティック修飾によるEBV再活性化についてRyo Kobayashi,Tomoko Ehara,Tetsuya MatsumotoDepartmentofMicrobiology,theTokyoMedicalUniversity
P2-D1-08 The ubiquitination of uniquitin activating enzyme is promoted by herpes simplex virus.ユビキチン活性化酵素のユビキチン化はHSV-1感染により亢進する。Marina Ikeda1),Akihiro Ito2),Tadashi Watanabe1),Masahiro Fujimuro1)
P2-D1-10 Possible association of disruption of human papillomavirus E1-NFκB feedback loop with progression of HPV associated lesions.HPV感染病変進行にヒトパピローマウイルスE1- NFκB負のフィードバック機構の破綻が関与する可能性Tomomi Nakahara,Takashi Yugawa,Tohru KiyonoNationalCancerCenterResearchInstitute,DivisionofCarcinogenesisandCancerPrevention
P2-D1-11 UBE1L2, an E1 enzyme specific for ubiquitin and FAT10, enhances KSHV production during lytic phaseユビキチン活性化酵素UBE1L2はKSHVの粒子産生に関わるAtsuko Sugimoto1,2),Tadashi Watanabe1),Yuichi Abe3),Jun Adachi3),Takeshi Tomonaga3),Masahiro Fijimuro1)
P2-D1-12 miR-27-mediated down-regulation of SNAP25 and TXN2 genes leads to inhibition of adenovirus infection.宿主miR-27によるSNAP25及びTXN2の発現抑制はアデノウイルス感染を阻害するMitsuhiro Machitani1,2),Fuminori Sakurai1),Keisaku Wakabayashi1),Masashi Tachibana1),Hiroyuki Mizuguchi1,3,4,5)
P2-D1-13 Promyelocytic Leukemia Protein (PML) Plays Beneficial Role on Kaposis Sarcoma Associated Herpesvirus Lytic ReplicationMd. Golzar Hossain,Eriko Ohsaki,Tomoyuki Honda,Keiji UedaDivisionofVirology,DepartmentofMicrobiologyandImmunology,OsakaUniversityGraduateSchoolofMedicine
P2-D1-14 KSHV decreases expression of CD81 and increases expression of CD151KSHVによるCD81発現抑制とCD151発現亢進の機構解析Kohei Hosokawa,Tadashi Watanabe,Masahiro FujimuroDepartmentofCellBiology,KyotoPharmaceuticalUniversity
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P2-D1-16 Truncated form of virus-associated RNA II, mivaRNA II, promotes adenovirus replication in a post-transcriptional gene silencing mannerアデノウイルス由来マイクロRNAによるウイルス増殖の促進Keisaku Wakabayashi1),Mitsuhiro Machitani1,2),Masashi Tachibana1,3),Fuminori Sakurai1),Hiroyuki Mizuguchi1,3,4,5)
P2-D1-17 Is HPVE7-UBR4 interaction regulated by the N-end rule pathway?HPVE7-UBR4分子相互作用は N-end rule経路によって制御されているかTakafumi TasakiDivisionofProteinRegulationResearch,KanazawaMedicalUniversity
P2-D1-18 DNMT3B expression and miR-145 promoter methylation in oral squamous cell carcinoma infected with both EBV and HPVChukkris Heawchiyaphum1,4),Chamsai Pientong1,4),Natcha Patarapadungkit2,4),Suchin Worawichawong3),Tipaya Ekalaksananan1,4)
P2-D1-19 EBV-encoded small RNAs (EBERs)-containing exosomes induce an immunosuppressive protein IDO in epithelial cells via IL-6 pathwayAti Burassakarn1,2),Chamsai Pientong1,2),Jureeporn Chuerduangphui1,2),Tipaya Ekalaksananan1,2)
PosterPoster Room(10F 1004-7, 1008, Foyer) Day 2 October 25 [Wed] 17:00~18:00
DNA viruses 2Chair:TomohikoSadaoka(KobeUniversityGraduateSchoolofMedicine)
P2-D2-01 The effect of reactivating latent virus in latent infection model of herpes virus to cognitive function by SAM P8 miceSAM P8マウスを用いたヘルペスウイルス潜伏感染モデルにおける潜伏ウイルス再活性化の認知機能に対する影響についてSeiichi Tanaka1),Yuko Taka Yashiki2),Hiroshi Nagashima2)
P2-D2-02 The influence of Gut Microbiota on reactivation of murine cytomegalovirusマウスサイトメガロウイルス再活性化に与える腸内細菌の影響Chikara Kohda,Satoshi Ino,Kazuo TanakaDepartmentofMicrobiologyandImmunology,SchoolofMedicine,ShowaUniversity
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P2-D2-03 Differential Macrophage/Microglial Responses to Cytomegalovirus Infection in the Developing Brain発育脳マクロファージ/ミクログリア細胞群におけるサイトメガロウイルス感染に対する応答の相違Isao Kosugi,Hideya Kawasaki,Toshihide IwashitaDepartmentofRegenerative&InfectiousPathology,HamamatsuUniversitySchoolofMedicine
P2-D2-04 Expression and function of microRNAs in nasal natural killer/T-cell lymphoma鼻性NK/T細胞リンパ腫におけるマイクロRNAの発現と機能解析Yuki Komabayashi1),Kan Kishibe2),Yasuaki Harabuchi2)
P2-D2-07 The relationship between loads of Merkel cell polyomavirus and carcinogenesisメルケル細胞ポリオーマウイルス量と発がんとの関連性についてYumiko Hashida,Tomonori Higuchi,Shigenobu Matsuzaki,Masanori DaibataDepartmentofMicrobiologyandInfection,KochiMedicalSchool,KochiUniversity
P2-D2-08 Salivary Secretion of Three Betaherpesviruses from Nursery School Children集団保育児における唾液中の3種ベータヘルペスウイルスDNAの排泄状況Masao Yamada1),Masahiro Watanabe2),Sadayoshi Torigoe3),Shigeru Suga4),Hikaru Namba1),Nobuko Yamashita1),Hirohito Ogawa1)
P2-D2-09 New giant virus isolated from Japanese hot spring forms a new NCLDV family温泉の底質泥から分離した新規巨大ウイルスは新たなNVLDVファミリーを形成するMasaharu Takemura1),Genki Yoshikawa2),Chihong Song3),Tomohiro Mochizuki4),Romain Blanc-Mathieu2),Kazuyoshi Murata3),Hiroyuki Ogata2)
The 65th Annual Meeting of the Japanese Society for Virology
P2-D2-10 Characterization of two adenoviruses isolated from Japanese wild bats国内のコウモリから分離された2種類のアデノウイルスの性状解析Tomoya Kobayashi1),Junki Maruyama2),Hiromichi Matsugo1),Haruhiko Kamiki1),Ken Maeda3),Ayato Takada2),Shin Murakami1),Taisuke Horimoto1)
P2-D2-11 Molecular epidemiology of Human Parvovirus B19 in patients suspected of having measles and rubella麻疹・風疹疑い患者検体から検出されるパルボウイルスB19遺伝子の分子疫学解析Hirokazu Adachi,Emi Hirose,Noriko Nakamura,Noriko Saito,Miyabi Ito,Yoshihiro Yasui,Hiroko MinagawaAichiPrefecturalInstituteofPublicHealth
P2-D2-12 Low concordance of oral and genital HPV infection among male STI patients in Vietnamベトナムの男性性感染症患者における口腔および性器HPV感染の低い一致Hai Ha Long Le1),Xiuqiong Bi1),Azumi Ishizaki1),Hung Van Le2,3),Trung Vu Nguyen2),Hiroshi Ichimura1)
P2-D2-13 Genetic Analysis of Human Adenoviruses associated with Urethritis尿道炎の原因となったアデノウイルスの遺伝子解析Satoshi Hiroi1),Takuya Kawahata1),Keiichi Furubayashi2)
P2-D2-14 Whole-genome analysis of HPV52/58 isolated from Japanese women with cervical intraepithelial neoplasia and invasive cervical cancer日本人の子宮頸部病変・子宮頸癌から分離されたHPV52/58の全ゲノム解析Iwao Kukimoto1),Yuri Tenjimbayashi1,2),Yusuke Hirose1,2),Mamiko Onuki2),Takashi Iwata3),Koji Matsumoto2)
PosterPoster Room(10F 1004-7, 1008, Foyer) Day 2 October 25 [Wed] 17:00~18:00
DNA viruses 3Chair:TadahiroSuenaga(ResearchInstituteforMicrobialDiseases,OsakaUniversity)
P2-D3-01 Profile of anti-VZV action of ASP2151(amenamevir) as a helicase-primase inhibitorヘリカーゼ/プライマーゼ阻害剤ASP2151(アメナメビル)のVZVに対する作用動態の検討Hideki Tani,Hiroshi Yamada,Ayumu Ohno,Kimiyasu ShirakiDepartmentofVirology,GraduateSchoolofMedicineandPharmaceuticalSciences,UniversityofToyama
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P2-D3-02 Analysis of relation between genetic polymorphisms of the pentameric complex of clinical HCMV isolates and neutralizationHCMV臨床分離株のペンタマーの遺伝子多型と中和の関係Ryo Kobayashi,Kohdai Oguri,Mao Abe,Akihiro Okumura,Hiroe Ohbayashi,Naoki InoueMicrobiologyandImmunology,GifuPharmaceuticalUniversity
P2-D3-03 The identification of CD4 helper epitopes against EB virus positive nasal NK/T cell lymphomaEBウイルス陽性鼻性NK/T細胞リンパ腫にたいするペプチドワクチン療法の開発Takumi Kumai1),Toshihiro Nagato2),Tatsuya Hayashi1,2),Hiroya Kobayashi3),Yasuaki Harabuchi2)
P2-D3-04 Augmentation of cellular immunity in herpes simplex virus type 1-infected mice by the oral administration of γ-aminobutyric acid.単純ヘルペスウイルス1型経皮感染マウスにおけるγ-アミノ酪酸の細胞性免疫賦活作用についてYoshio Sueshige,Satomi Terada,Hiromi Hasegawa,Chihiro Sugita,Hiroki Yoshida,Wataru Watanabe,Masahiko KurokawaGraduateSchoolofClinicalPharmacy,KyushuUniversityofHealthandWelfare
P2-D3-05 Development of a mouse model for adenoirus-conjunctivities diseaseアデノウイルス結膜炎における感染マウスモデルの樹立Masaru Shimada1),Michiko Mori4),Kenji Kawazoe2),Yoshitaka Miyanaga2),Kenji Okuda3),Nobuhisa Mizuki4)
P2-D3-08 Inhibition of phosphorylation of RNA polymerase II C-terminal domain by anti-human cytomegalovirus drug tricin抗ヒトサイトメガロウイルス活性のあるtricinによるRNA polymerase II C-terminal domainリン酸化の阻害Hidetaka Sadanari,Yuto Sugihara,Kazuhiro Fujimoto,Masaya Takemoto,Tohru Daikoku,Tsugiya MurayamaFacultyofPharmaceuticalSciences,HokurikuUniversity
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P2-D3-09 Inhibitory effect of capsaicin on PEL proliferationカプサイシンのPELに対する細胞増殖抑制効果Misato Moriguchi1),Dairi Shiraishi2),Tadashi Watanabe1,2),Masahiro Fujimuro1,2)
P2-D3-10 The development of the system that specifically induce herpes simplex virus type 1 DNA polymerase mutation derived acyclovir-resistanceDNAポリメラーゼ変異によるアシクロビル耐性HSV-1を特異的に誘導するためのシステム開発Hikaru Fujii,Shizuko Harada,Tomoki Yoshikawa,Natsumi Omura,Takuya Inagaki,Miho Shibamura,Hirofumi Kato,Souichi Yamada,Masayuki SaijoDepartmentofVirologyI,NationalInstituteofInfectiousDiseases
P2-D3-11 Development of a new therapy for EBV associated malignant neoplasmEBV関連悪性腫瘍に対する新規治療法の開発Go Matsuda1),Fuyuko Kawano1),Ken-Ichi Imadome1,2)
P2-D3-12 Tricin suppresses replication of herpes simplex virus type 1, type 2, and varicella-zoster virusTricinは単純ヘルペスウイルス1型・2型、ならびに水痘帯状疱疹ウイルスの増殖を抑制するMasaya Takemoto1),Hidetaka Sadanari2),Tohru Daikoku2),Keiko Matsubara2),Tsugiya Murayama2)
P2-D3-13 The study of drug evaluation using the model mouse of EBV-T/NK-LPD.難治性EBウイルス関連T/NKリンパ増殖性疾患モデルマウスを用いた治療薬の評価研究Fuyuko Kawano1),Go Matsuda1),Norio Shimizu3),Mamoru Ito4),Ken-Ichi Imadome1,2)
P2-D3-14 Persistent expression of a broadly neutralizing monoclonal antibody against HPVs by AAV-mediated gene transferAAVベクターを用いた遺伝子導入による抗HPV広域中和モノクローナル抗体の持続発現Seiichiro Mori,Osamu Kotani,Takamasa Takeuchi,Yoshiyuki Ishii,Iwao KukimotoPathogenGenomicsCenter,NationalInstituteofInfectiousDiseases
P2-D3-15 Antitumor effect of the HSV1 HF10 for metastatic cancer転移性腫瘍に対するHSV1 HF10の抗腫瘍効果Fumi Goshima1),Shinichi Esaki2),Gaku Takano2),Yoshitaka Sato1),Takayuki Murata1),Yukihiro Nishiyama1),Hiroshi Kimura1)
P2-D3-16 Oncolytic activity of HF10 for drug-resistant head and neck squamous cell carcinoma抗腫瘍ウイルスHF10の薬剤耐性頭頸部扁平上皮癌への効果Shinichi Esaki1,2),Fumi Goshima1),Gaku Takano1,2),Yoshitaka Sato1),Takayuki Murata1),Hiroshi Kimura1)
P2-P1-01 Rubella virus attaches to cells in at least two different ways.風疹ウイルスは異なる2種類の方法で細胞へ吸着するYoshio Mori,Noriyuki Otsuki,Masafumi Sakata,Kiyoko Okamoto,Makoto TakedaDepartmentofVirology3,NationalInstituteofInfectiousDiseases
P2-P1-03 Study of the nuclear/nucleolus import and export of bovine torovirus nucleocapsid (N) protein牛トロウイルスヌクレオカプシド蛋白質の核輸送機構に関する研究Shuji Iwata,Yui Matsunaga,Yukako Kawachi,Fumihiro Taguchi,Makoto UjikeDepartmentofVeterinaryScience,NipponVeterinaryandLifeScienceUniversity
P2-P1-04 Targeted inhibition of positive-strand RNA virus replication by fusion of a dsRNase to host factors involved in viral RNA replication複製複合体を構成する宿主因子と二本鎖RNA分解酵素の融合によるプラス鎖RNAウイルス増殖抑制タンパク質の分子設計Kazuhiro Ishibashi,Masayuki IshikawaInstituteofAgrobiologicalSciences,NARO
P2-P1-05 Attempts to grow human noroviruses and a sapovirus in vitro培養細胞におけるヒト由来ノロウイルス、サポウイルス増殖の試みTomoichiro Oka1,2),Garrett T Stoltzfus2),Chelsea Zhu2),Kwonil Jung2),Qiuhong Wang2),Linda J Saif2)
The 65th Annual Meeting of the Japanese Society for Virology
P2-P1-06 Characterization of Japanese encephalitis virus growth isolated from persistently infected mouse embryo cells affected type I/II interferon日本脳炎ウイルス持続感染細胞から産生されたウイルスのインターフェロンの影響と性状についてHiroko Toriniwa,Tomoyoshi KomiyaFacultyofHealthandMedicalScience,HokurikuUniversity
P2-P1-07 Analysis of the interaction between the genomic RNA of tick-borne encephalitis virus and RNA-binding proteins in neuronal granule machineryダニ媒介性脳炎ウイルスゲノムRNAとNeuronal Granuleを構成するRNA結合タンパク質との相互作用の解析Minato Hirano,Memi Muto,Mizuki Sakai,Hirofumi Kondo,Shintaro Kobayashi,Hiroaki Kariwa,Kentaro YoshiiLaboratoryofPublicHealth,FacultyofVeterinaryMedicine,HokkaidoUniversity
P2-P1-08 Analysis of the roles of tick RNAi related factors in the replication of tick-borne viruses in a tick cell lineダニ媒介性ウイルス感染におけるダニRNAi関連因子の機能解析Mao Kambara,Minato Hirano,Memi Muto,Mariko Ishizuka,Shintaro Kobayashi,Hiroaki Kariwa,Kentaro YoshiiLaboratoryofPublicHealth,GraduateSchoolofVeterinaryMedicine,HokkaidoUniversity
P2-P1-09 Analysis of host proteins interacting with the 3' untranslated region of tick-borne encephalitis virusダニ媒介性脳炎ウイルスの3´非翻訳領域に相互作用する宿主因子の解析Memi Muto1),Wataru Kamitani2),Mizuki Sakai1),Minato Hirano1),Shintaro Kobayashi1),Hiroaki Kariwa1),Kentaro Yoshii1)
P2-P1-11 Genome-Wide Screening Uncovers the Significance of N-sulfation of Heparan Sulfate as a Host Cell Factor for Chikungunya Virus Infectionゲノムワイドスクリーニングはヘパラン硫酸のN-硫酸基がチクングニアウイルスの感染に重要であることを明らかにした。Yusuke Maeda1),Atsushi Tanaka1,2),Uranan Tumkosit2),Shota Nakamura1),Daisuke Motooka1),Natsuko Kishishita1,2),Thongkoon Priengprom2),Areerat Sa-Ngasang3),Taroh Kinoshita1),Naokazu Takeda1,2)
P2-P1-12 Efficient replication of non-adapted hepatitis C virus isolates in cell culture適応変異を持たないC型肝炎ウイルスが効率的に複製する細胞培養系の確立Daisuke Yamane,Michinori KoharaDepartmentofMicrobiologyandCellBiology,TokyoMetropolitanInstituteofMedicalScience
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ay 2
P2-P1-13 In vitro blocking effect of two Wolbachia strains on diverse strains of dengue virusO’mezie Ekwudu1,2,3),Kym S. Lowry1),John G. Aaskov1),Gregor Devine2),Francesca D. Frentiu1)
P2-P1-15 Analysis of the cross reactivity of flaviviruses with Japanese encephalitis patients' sera showed the importance of neutralization test日本脳炎患者血清を用いたフラビウイルス間の交差反応の解析により、中和試験の重要性が確認されたTakahiro Maeki1),Shigeru Tajima1),Makiko Ikeda1),Fumihiro Kato1),Satoshi Taniguchi1),Eri Nakayama1),Kweng Chang Lim1),Tomohiko Takasaki2),Masayuki Saijo1)
P2-P1-16 Clarification of a mechanism of SAFV-induced demyelination in a mouse model感染マウスモデルを用いたサフォードウイルスの脱髄病変形成メカニズムの解明Kay Hagiwara1,2),Osamu Kotani1),Naoko Iwata-Yoshikawa1),Hideki Hasegawa1),Hiroyuki Shimizu1),Noriyo Nagata1)
P2-P1-17 Difference in the pathogenicity of ZIKV MR-766 and PRVABC59 strains in IFNAR1-knockout mice and mechanism of the differenceジカウイルスMR-766株とPRVABC59株のIFN受容体欠損マウスにおける病原性の違いとその機序の解明Fumihiro Kato1),Eri Nakayama1),Yasuhiro Kawai2),Chang-Kweng Lim1),Masayuki Saijo1),Shigeru Tajima1)
P2-P1-18 Molecular imaging of the brain in a mouse model infected with tick-borne encephalitis virusMya Myat Ngwe Tun1),Kodai Nishi2),Kouichi Morita3),Daisuke Hayasaka4)
P2-P1-19 Development of a flaccid paralysis mouse model after infection of enterovirus D68エンテロウイルスD68型感染後の弛緩性麻痺発現マウスモデルの構築Makoto Miyazaki1,2),Hiroyuki Saito3),Chihiro Shibata3),Doan Hai Yen4),Yujiro Arao2),Naoko Iwata-Yoshikawa1),Hideki Hasegawa1),Hiroyuki Shimizu4),Noriyo Nagata1)
The 65th Annual Meeting of the Japanese Society for Virology
P2-P1-20 Protease region of feline calicivirus p76 contributes to the up-regulation of inflammatory cytokines.ネコカリシウイルスのp76に保存されているプロテアーゼ領域は炎症性サイトカインの発現を誘導するRyota Koba,Yukina Uemura,Asuka Nimura,Yo Yumiketa,Yukinobu TohyaLaboratoryofVeterinaryMicrobiology,NihonUniversity
PosterPoster Room(10F 1004-7, 1008, Foyer) Day 2 October 25 [Wed] 17:00~18:00
P2-P2-01 Effect of the 350th amino acid substitution of 6K-E1 protein of Chikungunya virus on a rapid E1-antigen test sensitivityチクングニアウイルス迅速診断キットの反応性における6K-E1タンパク質350番目のアミノ酸の影響Emi E Nakayama1,2),Aekkachai Tuekprakhon2,3),Orapim Puiprom2),Tatsuo Shioda1,2),Pornsawan Leuangwuttiwong3)
P2-P2-02 Prevalence of Human Enterovirus and Human Parechovirus type 3 in hospitalized children in Saitama in 2016.2016年埼玉医科大学病院の小児入院患者におけるヒトエンテロウイルスおよびヒトパレコウイルスの検出Sanae MachidaMedicalResearchCenter,SaitamaMedicalUniversity
P2-P2-03 Prevalence of hand, foot and mouth disease and molecular epidemiology of coxsackievirus A16 in Toyama Prefecture, 1981-2015富山県における過去35年間の手足口病の流行とコクサッキーウイルスA16型の分子疫学Masae Itamochi,Noriko Inasaki,Mayumi Nagoya,Tetsuya Yoneda,Yumiko Saga,Takenori Takizawa,Masatsugu ObuchiDepartmentofVirology,ToyamaInstituteofHealth
P2-P2-05 Neutralization potency of the sera from Japanese encephalitis (JE) patients in Vietnam against genotype I and V JE virusesベトナム人日本脳炎患者血清の日本脳炎ウイルス遺伝子型I型およびV型に対する中和能解析Makiko Ikeda1),Shigeru Tajiama1),Thi Yhu Nguyen Thuy2),Hoai Linh Pham Ly3),Thi Hien Le Thu2),Nguyen Viet Hoang2),Le Thi Quynh Mai2),Meng Ling Moi4),Koichi Morita4),Chang Kweng Lim1),Masayuki Saijo1),Futoshi Hasebe5)
P2-P2-06 Development and evaluation of a rapid molecular diagnostic test for Zika virus infectionジカウイルスの迅速分子診断法の開発と臨床評価Yohei Kurosaki1),Bruneska Danyelly2),Haruka Abe1),Rokusuke Yoshikawa1),Filho Jose Luiz2),Jiro Yasuda1)
P2-P2-07 Active one-year surveillance of healthy adults to determine the rate of becoming an asymptomatic norovirus secretorノロウイルス感染環の維持に関する調査Naomi Sakon1),Rika Takada1),Jun Komano2)
P2-P2-08 Epidemic of norovirus GII.2 during 2016/17 season in Osaka City, Japan2016/17シーズンに大阪市で認められたノロウイルスGII.2流行Nobuhiro Iritani1),Daiki Kanbayashi1),Atsushi Kaida1),Niichiro Abe1),Seiji P Yamamoto1),Hideyuki Kubo1),Mamoru Noda2)
P2-P2-10 Development of Fluorescent RT-LAMP using Quenching probes for the detection of the Middle East Respiratory Syndrome CoronavirusKazuya Shirato1),Syouhei Senba3),Ikuyo Takayama2),Tsutomu Kageyama2),Tsugunori Notomi3),Shutoku Matsuyama1)
P2-P2-11 Norovirus GII.2 and its novel recombination in children with gastroenteritis in 2016 and 2017Aksara Thongprachum1,2),Sheikh Ariful Hoque1,3),Pattara Khamrin1,2),Shoko Okitsu1),Niwat Maneekarn2),Satoshi Hayakawa1),Hiroshi Ushijima1)
P2-P2-13 Molecular epidemiology of rhinovirus in children with acute respiratory illnesses in Toyama, Japan富山県におけるライノウイルス感染症と流行ウイルスの分子疫学Masatsugu Obuchi1),Tetsuya Yoneda1),Naohisa Shintani2),Shinichi Yagi3),Ayako Oguri4),Hiromichi Taneichi5),Noriko Inasaki1),Yumiko Saga1),Masae Itamochi1)
P2-P2-14 Molecular epidemiology of rubella viruses detected from exanthematous patients suspected of having measles in Aichi愛知県で麻しん疑い発疹症患者から検出された風疹ウイルスの分子疫学的解析Yoshihiro Yasui,Noriko Saito,Hirokazu Adachi,Noriko Nakamura,Emi Hirose,Miyabi Ito,Hiroko MinagawaAichiPrefecturalInstituteofPublicHealth
P2-P2-15 Detection of anti-viral antibody in meat juiceMeat juiceからの抗ウイルス抗体検出Kenzo Yonemitsu,Shohei Minami,Nao Nagata,Ryusei Kuwata,Hiroshi Shimoda,Ai Takano,Ken MaedaJointFacultyofVeterinaryMedicine,YamaguchiUniversity
P2-P2-16 Genetic analysis of norovirus GII.2 strains circulated in Toyama prefecture during the 2016-2017 season2016/17シーズンに富山県で流行したノロウイルスGII.2の遺伝学的解析Noriko Inasaki,Yumiko Aoyagi,Sumiyo Hasegawa,Tetsuya Yoneda,Yumiko Saga,Masae Itamochi,Masatsugu ObuchiDepartmentofVirology,ToyamaInstituteofHealth
P2-P2-17 An analysis of chronological change of capsid protein in norovirus GII.4 Sydney 2012 strain in Osaka between 2013 and 20162013-2016年における大阪府で検出されたノロウイルス GII.4 Sydney 2012株 カプシド蛋白質の経時的変遷Kazushi Motomura1,2),Rika Takada1),Naomi Sakon1),Takahiro Yumisashi1)
P2-P2-19 Evolutionary and functional analyses of the 5 prime untranslated region of recently circulating Enterovirus D68エンテロウイルスD68型近年流行株における5末端非翻訳領域の進化的・機能的特徴の解明Yuki Furuse1,2),Natthawan Chaimongkol2),Hitoshi Oshitani2)
P2-P2-20 Norovirus infection in an asymptomatic population in Indonesiaインドネシアにおけるノロウイルス不顕性感染の検討Takako Utsumi1,2),Maria Inge Lusida2),Zayyin Dinana2),Rury Mega Wahyuni2),Laura Navika Yamani2), Juniastuti2), Soetjipto2),Chieko Matsui1),Lin Deng1),Takayuki Abe1),Yen Hai Doan3),Yoshiki Fujii3),Kazuhiko Katayama4),Ikuo Shoji1)
P2-P2-21 Production and characterization of a monoclonal antibody against ZIKV proteaseジカウイルスプロテアーゼに対するモノクローナル抗体の作製および性状解析Yutaro Yamaoka1,2),Satoko Matsunaga1),Hideaki Shimizu3),Nobuhiko Okabe3)
P2-P3-01 Immunological response in a patient of noroviruses infection associated with raw oyster生カキに関連したノロウイルス感染症例における免疫応答Hiroyuki Saito1),Yuko Shimizu2),Hiroko Sato1),Wakako Akino1),Satoshi Hayakawa2),Hiroshi Ushijima2)
The 65th Annual Meeting of the Japanese Society for Virology
P2-P3-03 Bioinformatics Analyses Identified Phase-Specific Heart Biomarkers and Blood Surrogate Markers for a Mouse Model of Viral Myocarditisウイルス性心筋炎マウスモデルを用いたバイオインフォマティクス解析による病期特異的心臓バイオマーカーおよび血中代替マーカーの同定Seiichi Omura1),Fumitaka Sato1),Ah-Mee Park1),Mitsugu Fujita1),J. Steven Alexander2),Phillip C.s.r. Kilgore3),Urska Cvek3),Ikuo Tsunoda1)
P2-P3-04 Analysis of an epitope located near the glycosylation site on the domain II of dengue virus type 1 E proteinデングウイルス1型EタンパクドメインII上の糖鎖近傍エピトープの解析Tomohiro Kotaki1),Atsushi Yamanaka2),Eiji Konishi2),Masanori Kameoka1)
P2-P3-05 Establishment of a neutralization assay for multiple flaviviruses based on single-round infectious particles一回感染性ウイルスを用いた中和アッセイによるフラビウイルス属の鑑別診断系の確立Mami Matsuda1),Atsushi Yamanaka2,3),Kentaro Yoshii4),Koichi Watashi1),Hideki Aizaki1),Eiji Konishi2,3),Tomohiko Takasaki5),Takaji Wakita1),Ryosuke Suzuki1)
P2-P3-06 Development of a new IgM-ELISA against tick-borne encephalitis using subviral particlesダニ媒介性脳炎ウイルスのウイルス様粒子を用いた新規IgM-ELISA系の開発Miki Nakayasu,Shintaro Kobayashi,Minato Hirano,Memi Muto,Hiroaki Kariwa,Kentaro YoshiiLaboratoryofPublicHealth,GraduateSchoolofVeterinaryMedicine,HokkaidoUnivercity
P2-P3-07 Acquired immune response and viral load in rubella免疫獲得後の風しん発症例における抗体免疫と体内ウイルスの動態Tatsuya Miyoshi1),Kiyoko Uchino1),Tomoyuki Tanaka2),Yoshio Mori3)
P2-P3-11 Site of action of Cyclofenil to inhibit dengue virus replicationサイクロフェニルがデングウイルスの増殖を抑制する作用点の同定Daiki Tohma1,2),Fumihiro Kato1),Takayuki Hishiki3),Haruko Takeyama2),Chang-Kweng Lim1),Shigeru Tajima1),Masayuki Saijo1)
P2-P3-12 Simultaneous blockage of hepatitis C virus genome replication and particle production by a novel DGAT inhibitorChoongho Lee1),Ja-Il Goo2),Mi Il Kim1),Sung-Jin Lee1),Moonju Choi1),Marc P Windisch3),Yongseok Choi2)
P2-P3-14 Identification of small molecule inhibitors of human norovirus RNA genome replicationSungjin Lee,Guanghai Jin,Kyeong Lee,Choongho LeeDonggukUniversityCollegeofPharmacy
P2-P3-15 Novel ER alpha-glucosidase inhibitors compromise the replication of coronaviruses新規小胞体α-グルコシダーゼ阻害薬による抗コロナウイルス機構に関する研究Saori Kosaka1),Chiharu Tsubouchi1),Shun Uema2),Momoko Onda2),Shutoku Matsuyama3),Wataru Hakamata2)
P2-N1-01 Measles virus-mediated membrane fusion: Structural basis for its inhibition by inhibitors and activation caused by mutations麻疹ウイルスによる膜融合:阻害剤による阻害機構と変異による活性化の構造基盤Yoshinari Fukuda1),Takao Hashiguchi1),Rei Matsuoka2),Daisuke Kuroda3),Marie Kubota1),Daisuke Kohda2),Yusuke Yanagi1)
P2-N1-02 Specified amino acids at the dimer interface of the parainfluenza virus HN head domain are required for the virus-specific HN-F interactionパラインフルエンザウイルスのウイルス特異的なHN- F相互作用には、HN蛋白head領域(二量体境界部)の特定のアミノ酸群が必要であるMasato Tsurudome1),Morihiro Ito2),Machiko Nishio3),Tetsuya Nosaka1)
P2-N1-05 Molecular function analysis of rabies virus L protein by using an L gene-deficient virusL遺伝子欠損型狂犬病ウイルスを活用したL蛋白質の機能解析Kento Nakagawa1),Yuki Kobayashi2),Naoto Ito1,3),Yoshiyuki Suzuki4),Kazuma Okada3),Machiko Makino3),Hideo Goto3),Tatsuki Takahashi1),Makoto Sugiyama1,3)
P2-N1-06 A regulatory role of intergenic trinucleotides on Sendai viral gene expressionセンダイウイルス遺伝子間3塩基配列の転写制御機能Ryoko Kawabata1),Asuka Yoshida2),Mahiro Nakanishi3),Hakuhiro Sho1),Hiroaki Natsuhara1),Takemasa Sakaguchi1),Takashi Irie1)
P2-N1-07 The expression of hendra virus F gene is downregulated by its untranslated regionヘンドラウイルスF遺伝子の発現は,F遺伝子非翻訳領域によって調節されているShumpei Watanabe1,2),Glenn Marsh2),Masayuki Shimojima1),Shuetsu Fukushi1),Takeshi Kurosu1),Masayuki Saijo1)
P2-N1-08 Comparative analysis of viral replication and transcription function of Severe fever with thrombocytopenia virus and Heartland virusミニゲノム法を用いた重症熱性血小板減少症候群ウイルスとハートランドウイルスのウイルスゲノム転写複製機能の解析Satoshi Taniguchi1),Masayuki Shimojima1),Shuetsu Fukushi1),Takeshi Kurosu1),Hideki Tani2),Tomoki Yoshikawa1),Shigeru Morikawa3),Fumihiro Kato1),Takahiro Maeki1),Shigeru Tajima1),Chang-Kweng Lim1),Masayuki Saijo1)
P2-N1-09 Targeting of bornavirus sequence by piRNA derived from an endogenous bornavirus element in GC2 cells内在性ボルナウイルスエレメント由来piRNAによるボルナウイルス制御Tomoyuki Honda1,2),Xiaoshu Liu2),Bea C. Garcia2),Nicholas F. Parrish2),Keizo Tomonaga2)
P2-N1-11 Dissecting the network of viral RNAs in influenza A virus virionインフルエンザウイルス粒子内ゲノムRNAネットワークの解明Naoki TakizawaLaboratoryofvirology,Instituteofmicrobialchemistry(BIKAKEN)
P2-N1-12 Studies on the Intracellular Trafficking of SFTSV Structural Proteins重症熱性血小板減少症候群ウイルスの構造蛋白質の細胞内輸送Tapiwa Lundu1,3),Yoshimi Tsuda2),Kenta Shimizu2),Shintaro Kobayashi1),Kentaro Yoshii1),Kumiko Yoshimatsu2),Jiro Arikawa2),Hiroaki Kariwa1)
The 65th Annual Meeting of the Japanese Society for Virology
P2-N1-13 Function of the bovine parainfluenzavirus type 3 M protein in virus particle formation牛パラインフルエンザウイルス3型Mタンパク質のウイルス粒子形成における機能解析Kaoru Takeuchi,Haruna UedaDivisionofBiomedicalScience,FacultyofMedicine,UniversityofTsukuba
PosterPoster Room(10F 1004-7, 1008, Foyer) Day 2 October 25 [Wed] 17:00~18:00
P2-N2-01 Binding of mumps virus to glycan receptorsムンプスウイルスと糖鎖受容体との結合特異性Marie Kubota,Takao Hashiguchi,Yusuke YanagiDepartmentofVirology,FacultyofMedicine,KyushuUniversity
P2-N2-02 The ability of SFTSV NSs differs between human and mouse.SFTSVのNSsの活性はヒトとマウスで異なる挙動を示す。Rokusuke Yoshikawa,Jiro YasudaDepartmentofEmergingInfectiousDiseases,InstituteofTropicalMedicine(NEKKEN),NagasakiUniversity
P2-N2-03 Involvement of the R2TP complex in biogenesis of mumps virus L proteinムンプスウイルスのLタンパク質合成におけるR2TP complexの関与Hiroshi Katoh1),Masafumi Sakata1),Yuichiro Nakatsu1),Reiko Nakagawa2,3),Minoru Kidokoro1),Makoto Takeda1)
P2-N2-04 Nucleocapsid protein of Nipah virus suppresses host interferon responses by interfering with STAT complex formationニパウイルスN蛋白質によるSTAT複合体形成の阻害を介するIFN応答の抑制Akihiro Sugai,Hiroki Sato,Ikuyo Takayama,Misako Yoneda,Chieko KaiLaboratoryAnimalResearchCenter,TheInstituteofMedicalScience,TheUniversityofTokyo
P2-N2-07 Polymerase L protein is responsible for the adaptation of avian bornavirus to mammalian cellsBea Clarise Baluyot Garcia1,2),Yukiko Sassa2),Yusuke Matsumoto3),Akiko Makino1),Keizo Tomonaga1,2)
P2-N2-08 ADAR2 plays a key role in the maintenance of persistent infection of Borna disease virusADAR2はボルナウイルスの持続感染の維持に重要であるMako Yanai1,2),Akiko Makino1),Keizo Tomonaga1,2)
P2-N2-11 Role of UBXN1, a novel host protein interacting with measles virus V protein, in neuropathogenicityVタンパク質新規相互作用因子UBXN1の麻疹ウイルス神経病原性における寄与の検討Shotaro Uchida,Tetsuro Arai,Hiroki Sato,Chieko Kai,Misako YonedaLaboratoryAnimalResearchCenter,InstituteofMedicalScience,TheUniversityofTokyo
P2-N2-12 Measurement of temperature of Influenza virus infected cellインフルエンザウイルス感染細胞の温度計測Ayae HondaResearchCenterofPhamacy,NihonUniversity
P2-N2-13 Near-infrared fluorescent protein iRFP720 is optimal for in vivo fluorescence imaging of rabies virus infection近赤外蛍光蛋白質iRFP720は狂犬病ウイルスのin vivo蛍光イメージング解析に適するKentaro Yamada1),Minori Isomura2),Kazuko Noguchi2),Akira Nishozono2)
P2-N3-01 Lethal infection of embryonated chicken eggs by Hazara virus; a surrogate model for Crimean-Congo hemorrhagic fever virus pathogenicityクリミア・コンゴ出血熱ウイルスモデル:ハザラウイルスは発育鶏卵において致死性感染を示すYusuke Matsumoto,Keisuke Ohta,Machiko NishioDepartmentofMicrobiology,SchoolofMedicine,WakayamaMedicalUniversity
P2-N3-02 Cytopathogenicity of new isolates of feline morbilliviruses from urine specimens of Japanese cats国内ネコ尿検体から新規分離したネコモルビリウイルス株の培養における病原性についてYuiko Hashizume1),Eun-Sil Park2),Shigeru Morikawa2),Tetsuya Furuya1)
P2-N3-03 Biological characterization of virus produced from persistently infected cells of feline morbillivirusネコモルビリウイルス持続感染細胞由来ウイルスの生物学的性状解析Shoichi Sakaguchi1,2),Rie Koide2),Keiko Shindo3),Takeshi Noda3),Tetsuya Mizutani1),Takayuki Miyazawa2)
P2-N3-05 Susceptibility of poultries to H5N6 subtype highly pathogenic avian influenza virus isolated in Japan during 2016 to 20172016-2017年に日本で分離されたH5N6亜型高病原性鳥インフルエンザウイルスの家禽における感受性Yuko Uchida,Junki Mine,Nobuhiro Takemae,Ryota Tsunekuni,Taichiro Tanikawa,Takehiko SaitoInfluenzaunit,Divisionoftransboundaryanimaldiseases,NationalInstituteofAnimalHealth,NationalAgricultureandFoodResearchOrganization
P2-N3-06 Neuropathogenic determinants of Akabane virus in young cattleアカバネウイルスの若齢牛に対する神経病原性を決定する因子の探索Katsuya Motohashi,Akiko Uema,Keita Sugiura,Hiroomi Akashi,Shin Murakami,Taisuke HorimotoGraduateSchoolofAgriculturalandLifeSciences,TheUniversityofTokyo
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P2-N3-07 The first case of severe fever with thrombocytopenia syndrome in a cat猫における重症熱性血小板減少症候群の発症Ken Maeda1),Nao Nagata1),Kenzo Yonemitsu1),Shohei Minami1),Ryusei Kuwata1),Hiroshi Shimoda1),Ai Takano1),Kazuo Suzuki2),Asayo Okimi3),Shigeru Morikawa4)
P2-N3-08 Expression and antigenic characterization of recombinant nucleoprotein of shrew-borne hantaviruses and its application for serologyトガリネズミ目由来ハンタウイルスの組換核蛋白を用いた抗原性の解析と血清学への応用Kumpei Nishigami1),Satoshi Arai2),Kenta Shimizu1),Yoshimi Tsuda1),Shigeru Morikawa2),Richard Yanagihara3),Jiro Arikawa1),Kumiko Yoshimatsu1)
P2-N3-10 Discovery of diverse mosquito-borne bunyaviruses in field-collected mosquitoes蚊が保有する多様な新規ブニヤウイルスYasuko Orba1),Bernard M Hang'ombe2),Aaron S Mweene3),Paulina D Anindita1),Phongphaew Wallaya1),Yuji Wada1),Michihito Sasaki1),Yuki Eshita4),Hirofumi Sawa1,5,6)
P2-N3-12 Characterization of H5N6 highly pathogenic avian influenza viruses isolated from wild birds and zoo animals in Japan in 2016-17Kosuke Soda,Tatsufumi Usui,Hiroshi Ito,Hiroichi Ozaki,Toshiyuki Murase,Tsuyoshi Yamaguchi,Toshihiro ItoAvianZoonosisResearchCenter,FacultyofAgriculture,TottoriUniversity
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P2-N3-13 Human metapneumovirus with 180 nucleotide-duplication in the G gene detected in Sendai city, JapanNaganori Nao1),Ko Sato2),Miwako Saikusa3),Makoto Takeda1),Hidekazu Nishimura2)
P2-N4-01 A role of oxidative phosphorylation for mitochondrial antiviral innate immunity.ミトコンドリアを介する抗ウイルス自然免疫応答における酸化的リン酸化の役割Takuma Yoshizumi1),Hiromi Imamura2),Takumi Koshiba1,3)
P2-N4-02 Rabies virus matrix protein is involved in the formation of antiviral stress granules in infected cells狂犬病ウイルスM蛋白質は抗ウイルスストレス顆粒の形成に関与するTatsunori Masatani1),Koji Onomoto2),Naoto Ito3),Makoto Ozawa1),Makoto Sugiyama3),Mitsutoshi Yoneyama2),Takashi Fujita4)
P2-N4-03 Effect of human metapneumovirus M2-2 on Toll-like receptor 7/9-dependent K63-linked polyubiquitination and phosphorylation of IRF7ヒトメタニューモウイルスM2-2蛋白質によるTLR7/9経路依存性のIRF7修飾への影響Yoshinori Kitagawa1),Miki Kohno1,2),Takumi Tsukamoto1,2),Masae Itoh2),Bin Gotoh1)
P2-N4-04 Identification of a novel domain of SFTS virus NSs required for anti-interferon activitySFTSウイルスNSsタンパク質の抗インターフェロン活性に必須なドメインの同定Miyu Moriyama,Takeshi IchinoheDivisionofViralInfection,DepartmentofInfectiousDiseaseControl,InternationalResearchCenterforInfectiousDiseases,InstituteofMedicalScience,theUniversityofTokyo
P2-N4-05 Does type I or type III interferon more strongly suppress measles virus infection in epithelial cells?I型インターフェロンとIII型インターフェロンのどちらが上皮細胞において麻疹ウイルス感染をより強く抑制するか?Midori Taniguchi1),Shinji Ohno2),Yusuke Yanagi1)
P2-N4-06 Suppression of PKR signaling pathway by nonstructural protein of severe fever with thrombocytopenia syndrome virus重症熱性血小板減少症候群ウイルスの非構造タンパク質NSsはPKR経路を抑制するNodoka Kasajima1),Keita Matsuno1,2),Shiho Torii1),Takahiro Hiono1),Masatoshi Okamatsu1),Hideki Ebihara3),Yoshihiro Sakoda1)
P2-N4-07 Effects of inactivated S. pneumoniae on immunity responding to RSV infection in mice.不活化肺炎球菌によるRSV感染応答への影響Aki Miyauchi1),Toshi Akashi2),Seiko Hashiguchi1),Hiroki Yoshida3),Chihiro Sugita3),Masahiko Kurokawa3),Wataru Watanabe1)
P2-N4-08 Development of novel avian paramyxovirus vectors with long-term mucosal and humoral immune responses against an Ebola virus glycoproteinエボラウイルスに対する新規トリパラミクソウイルスベクターワクチンの開発Asuka Yoshida,Shin-Hee Kim,Vinoth K Manoharan,Siba K SamalVirginia-MarylandRegionalCollegeofVeterinaryMedicineUniversityofMaryland
P2-N4-09 Immune Inducibility of Recombinant Measles Virus Vaccines against Nipah Virus Infection in Hamsters.Che Lin,Chieko Kai,Misako YonedaInstituteofMedicalScience,TheUniversityofTokyo
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P2-N4-10 Effects of gamma-aminobutyric acid on RSV infection in miceγ-アミノ酪酸(GABA)のRSウイルス感染への効果Kaede Hatano1),Seiko Hashiguchi1),Aki Miyauchi1),Toshi Akashi2),Hiroki Yoshida3),Chihiro Sugita3),Masahiko Kurokawa3),Wataru Watanabe1)
P2-N4-11 Effects of protease inhibitors on replication of human parainfluenza virus type 3 in primary cultures of human tracheal epithelial cellsYuka Iino1),Ami Ide1,2),Ko Sato2),Oshi Watanabe2),Suguru Omiya2),Tohru Kiyono3),Emiko Isogai1),Mutsuo Yamaya4),Hidekazu Nishimura1)
P2-N4-12 Construction of a simple method for screening of anti-arena virus compounds by virus-induced cytotoxicityウイルス増殖による細胞傷害性を指標とした簡便なアレナウイルス阻害剤のスクリーニングアッセイ系の構築Akihiko Sato1,3),Shinsuke Toba1,3),Akihiro Ishi3),Haruaki Nobori1,3),Etsuko Hayashi3),Ryu Yoshida1),Masanori Kobayashi2),Jiro Arikawa4),Kumiko Yoshimatsu4),Yasuko Oba3),Hirofumi Sawa3)
P2-N4-13 The protein kinase inhibitors inhibit entry of severe fever with thrombocytopenia syndrome virus in vitroプロテインキナーゼ阻害剤による重症熱性血小板減少症候群ウイルスの侵入阻害Hideki Tani1,2),Hikaru Fujii2),Satoshi Taniguchi2),Shuetsu Fukushi2),Takeshi Kurosu2),Masayuki Shimojima2),Shigeru Morikawa3),Masayuki Saijo2)
P2-N4-15 Analysis of epitope on rabies virus phosphoprotein recognized by a single chain variable fragment which inhibits rabies virus growth狂犬病ウイルスの増殖を阻害する抗P蛋白質single chain variable fragmentのエピトープ解析Yoshihiro Kaku1),Ken-Ichi Inoue2),Satoshi Inoue1),Akira Noguchi1),Shigeru Morikawa1)
P2-N4-16 Development of a bivalent-vaccine against MERS-CoV and Rabies virus by using a recombinant replication-deficient rabies viral vector非増殖性組換え狂犬病ウイルスベクターを用いた中東呼吸器症候群と狂犬病に対する2価ワクチンの開発Hirofumi Kato1,2),Mutsuyo Takayama-Ito1),Itoe Iizuka-Shiota1,3),Guillermo Posadas-Herrera1),Madoka Horiya4),Masaaki Satoh1),Kinjiro Morimoto5),Masayuki Saijo1),Chang-Kweng Lim1)
P2-N4-17 Development of a high-purity and high titer BoDV vector purification protocol高純度・高力価ボルナウイルスベクター精製法の開発Yoji Kakuya1,2),Madoka Sakai1,2),Shohei Kojima1,2),Akiko Makino1),Yumiko Komatsu1,3),Keizo Tomonaga1,2)
P2-N4-18 Development of a novel high-sensitive nucleic acid testing method for quantifying VSV vector in vivo水疱性口内炎ウイルスベクターの生体内での定量を可能にする新規高感度核酸検査法の開発Kenta Tezuka,Kazu Okuma,Isao HamaguchiDepartmentofSafetyResearchonBloodandBiologicalProducts,NationalInstituteofInfectiousDiseases
P2-N4-19 Characterization of BoDV vector for gene delivery to iPSCsiPS細胞に対する遺伝子導入に向けたBoDVベクターの評価Yumiko Komatsu1,2),Yasuhiro Ikeda3),Yoji Kakuya1,4),Akiko Makino1),Keizo Tomonaga1,4)