犊犊犊犊犊 Toxocara vitulorum 犊犊 07 ( 2 犊 犊犊 犊犊犊 犊犊犊 )
犊弓首蛔虫Toxocara vitulorum
动医 07 ( 2 )班 王晶 吕嘉敏 卢沛兰
Introduction
Kingdom Animalia (动物界)Phylum Nemathelminthes (线形动物门)Class Secernentea (尾感器纲)Order Ascaridata (蛔目)
Family Toxocaridae (弓首科)Genus Toxocara (弓首属)
Scientific classification
Host: cattle and buffalo
Site: small intestine (小肠)
Morphology
Size: large
The largest intestinal parasite of cattle
Shape :
it has a cylindrical( 圆柱状 ) form , taper
ing at either end( 两端尖 ), and the body is
covered by a colorless, somewhat transluc
ent( 半透明的 ), layer, the cuticle ( 角皮 ).
11 ~ 26cm
14 ~ 30cm
70~80 μm x 60 ~ 66 μm
Egg( 卵 )
Life cycle
Adult nematodes develop only in the small
intestines (小肠) of young calves under 6
months of age.The eggs do not hatch in the environment, but
larvae in the eggs develop to the infective second
stage larvae ( L2 ) .Direct Life Cycle( 直接型生活史 )
Egg Infective egg (with L2)
L2 在母牛小肠孵化
适宜的温度、湿度
移行
至肝、肺、肾等发育成 L3
L4
移行至子宫 胎牛吞入体内
犊牛小肠 Adult
经粪便排出
进入胎盘羊水液
Transmission from mother to fetus ( 胎儿 )across the placenta (胎盘)
Egg
L3进入小肠
乳腺乳汁
Adult
Infective egg (with L2)
移行
适宜的温度、湿度 L2 在母牛小肠孵化
L4
Transmission by the milk of the dam
至肝、肺等发育成 L3
移行
In some parts of the world calves may be
come infected ingesting infective eggs fr
om the environment , for example, in th
e southern part of Africa.
Egg 适宜的温度和湿度
肝脏 L3
门静脉
心 肺动脉
细支气管、支气管、气管
肺泡
进入口腔
小肠
Adult 经粪便排出
咽部
Infective egg (with L2)
L2 在犊牛小肠孵化
Ingestion of infective eggs
后腔静脉 肝静脉
肺 L4
Epidemiology
cattle and buffalo Bos ( 牛属 ) calves seem to be less suscepti
ble than Bubalus ( 水牛属 ) calves Toxocara vitulorum is found mostly in trop
ical and subtropical climates worldwide
Calves can be infected both transplacental
ly (经胎盘地) before birth and via milk
after birth, while they may also become inf
ected ingesting infective eggs from the env
ironment.
Transmission through milk is the major
route of infection of calves in Southeast
Asia. But studies in the southern part of
Africa have indicated that the ingestion of
infective eggs from the environment is the
most common route of infection there.
Larvae develop into adults in the small
intestines of young calves, and then begin
shedding eggs in the feces contaminating
the environment and other animals.
The thick-walled eggs are very resistant to adverse climatic and environmental conditions.
At temperatures between 20 and 30ºC they can remain infective for a long period of time (several years).
Prevalence of Toxocara vitulorum in beef cattle in North Central Florida
(Davila , et al 2010)
Calf age Prevalence
<3 months 29/165 = 17.6%
3–4 months 5/113= 0.4%
5–6 months 1/108 = 0.9%
7–9 months 0/47 = 0%
The prevalence( 感染率 ) in most countries is between 5 and 50% and has been influenced by animal species, sex and seasonal variations.
Prevalence can reach 100%, when uncontrolled in the field, since each female worm can lay up to 100 000 eggs per day.
Lesions
punctate hemorrhage 点状出血 eosinophilia 嗜酸性粒细胞增多 hemorrhage 出血 ulcer 溃疡 intestinal obstruction 肠阻塞 intestinal perforation 肠穿孔
Signs enteritis 肠炎 emaciation 消瘦 lethargy 嗜睡 fever, couch, dyspnea( 呼吸困难 ) a stink smell likes acetone( 丙酮 ) diarrhea 腹泻 stomachache 腹痛 exhaustion 衰竭 intestinal obstruction 肠阻塞
intestinal perforation 肠穿孔
Diagnosis
Epidemiological analysis 流行病学分析 history of disease ( 病史 ) 、 age 、 feeding and manage
ment practices (饲养管理方式)、 season of occurrenc
e (发病季节)、 climate , etc.
Clinical signs 临床症状 Faecal examination: by flotation method
Post-mortem examination( 死后剖检 )
Diagnosis for treatment ( 治疗性诊断 )
Control
The principle of control is to prevent the
parasites from having an effect on the
calves and from contaminating the
environment with eggs.
anthelmintics( 驱虫药 )
盐酸左旋咪唑 Levamisole 8mg/kg po/im
丙硫苯咪唑 Albendazole 10~15mg/kg po
伊维菌素 Lvermectin 0.3mg/kg sc/po symptomatic treatment 对症治疗
1 、 Treatment 治疗
2 、 prevention 预防 preventative deworming 预防性驱虫 Eliminating the immature parasites before they can h
arm the calves and start egg production ; Calves under 20 days of age Sanitation 卫生 e.g. Harmless disposal of feces 粪便无害化处理 isolated feeding 隔离饲养
It is advised that all calves under 6
months of age should be used anthel
mintics( 驱虫药 ) in endemic area.
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