1 PORTFOLIO VIRAL DISEASE KHD 202 Lecture (s): Prof. Dr, Rahaju Ernawati, Drh., M.Sc Drh. Adi Prijo Rahardjo, M.Si Dr. Jola Rahmahani,Drh., M.Kes Prof. Dr. Fedik Abdul Rantam, Drh. Prof. Dr. Suwarno, Drh., M.Si DEPARTMENT OF MICROBIOLOGY FACULTY OF VETERINARY MEDICINE UNIVERSITAS AIRLANGGA
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PORTFOLIO
VIRAL DISEASE
KHD 202
Lecture (s):
Prof. Dr, Rahaju Ernawati, Drh., M.Sc
Drh. Adi Prijo Rahardjo, M.Si
Dr. Jola Rahmahani,Drh., M.Kes
Prof. Dr. Fedik Abdul Rantam, Drh.
Prof. Dr. Suwarno, Drh., M.Si
DEPARTMENT OF MICROBIOLOGY
FACULTY OF VETERINARY MEDICINE
UNIVERSITAS AIRLANGGA
2
LIST OF CONTENTS
MODULE HANDBOOK :
A. Course Identity ........................................................................................................ 3
B. Maping LO to CO ................................................................................................... 6
C. Course topic ............................................................................................................ 6
D. Assessment Rubric .................................................................................................. 7
E. Assessment system .................................................................................................. 9
COURSE ASSESSMENT TA 2017/2018 :
A. Course Outcome Evaluation ................................................................................... 10
B. Course Development Plan ....................................................................................... 16
C. Summary of Lecturer Evaluation by Students ....................................................... 16
44. Epizootic cycle caused by ebola virus appear sporadically producing high mortality;
1. Non human primates 2. Precede human outbreaks 3. Acute disease
4. Transmission human to human
III. ANSWER the following questions by using the key below:
A. if both statement and reason are true and related cause and effect
B. if both statement and reason are true but not related cause and effect
C. if the statement is true but the reason is false
D. if the statement is false but the reason is true
E. if both statement and reason are false
45. Differential diagnosis of FMD is Stomatitis Vesicularis because SV and FMD caused by
the viruses of the same genus.
46. Ebola virus disease (formerly called Ebola Hemorrhagic disease) is a severe, often fatal,
disease in humans and non-human primates because ebola viruses have the ability to
turn internal organs into a soup that promptly flows out of the body.
47. The incubation period of Rabies are 14 days, because the migration time of the Rabies
virus to reach the central nervous system are fixed.
48. Rabies Fixed virus strain cannot be detect in the dog’s saliva, because the Rabies Fixed
virus strain migrate to the central nervous system by neurons.
49. Epizootic strains caused Equine Encephalitis more harm than Enzootic strain, because
The strain of enzootic of Epizootic Equine Encephalitis is a virus strain that has been
experienced in the natural attenuation.
50. Stomatitis vesikularis called Pseudo FMD CAUSE stomatitis vesikularis have clinical
symptoms similar aphthae Epizootika
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Final Semester Exam Infectious Viral Disease II (I.P. VIRAL) Faculty of Veterinary Medicine – Airlangga University Semester : IV Day/date : Thursday, 06 th July 2017 Time : 80 minutes_______________________________________________________ I. CHOOSE ONE OF THE MOST CORRECT ANSWER 1. To prevent puppies against canine distemper it may be possible by using vaccines virus of; A. Parvovirus B. HPD C. Hepatitis Contagiousa Canis
D. Rinderpest E. Feline panleukopenia 2. Canine distemper is caused by; A. Paramyxovirus B. Orthomyxovirus C. Pseudomyxovirus D. Adenovirus E. Parvovirus 3. Transmission of smallpox disease in pigs (pigpox) the most dominant over by the vector namely: A. Mosquito B. Flies C. Tick D. Ectoparasites E. Culex 4. Clinical symptoms ORF in affected sheep are described below, except: A. Crusting skin B. Lesions in the mouth C. Lesions in the nasal D. Lesions on Vulva E. Lesions on the ear 5. The following property is not about Jembrana disease: A. Host affected is Bali cattle B. Caused by lentivirus C. There are enlargement and swelling of limphnode and spleen D. There are clinical symptoms hypersalivation and haemorrhagic diarrhea E. Transmitted by mosquito vector 6. The following statement is character of Malignant catarrhal fever , except :: A. Caused by Rhabdovirus B. There was an erosion lesions in the oral mucous membrane and interdigital space C. The causative virus has antigenic relationship with pestis suum D. Encephalitis is one of the clinical symptoms E. Causative virus can be inoculated in embryonated egg 7. The following statement is character of BVD-MD, except: A. Caused by Arbotogavirus B. Can be adapted on pig kidney cell C. Certain serotype can be aglutinate erythrocytes D. Can be cultivated in embryonated egg E. There is antigenic relationship with pestis suum 8. Leucopenia in blood examination was found in; A. Rinderpest D. Jembrana B. MCF E. FMD C. BVD-MD 9. The spread of west nile virus in animals is through vectors: A.Culex sp D. Anopheles sp
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B. Aides Aegypty E. Stomoxys Calsitrans C. Aides Albopicus
10. The laboratory diagnosis of west nile virus infected animal is the following methods: A. PCR B. ELISA C. CFT D. AGPT E. HA-HI 11. This viral infections play a role within "Kennel Cough Syndrome" in dog: A. Parainfluenza virus 1 B. Parainfluenza virus 2 C. Parainfluenza virus 3 D. Influenza A E. Influenza B
12. "Shipping Fever" is often associated with : A. Parainfluenza virus 1 B. Parainfluenza virus 2 C. Parainfluenza virus 3 D. Sendai virus E. Simian virus 5
13. Bacterial infection that often as a secondary infection in Canine Distemper : A. Salmonella B. Pasteurella C. Mycoplasma D. Ecoli E. Bordetella bronchoseptica
14. The following symptoms appear in infected horse with Influenza A , except: A. Conjunctivitis B.Increasing of body temperature C. Coughing D. Red nose mucous E. Diarrhea
15. Protein that has important function when hantavirus infects a cell is :
A. Polymerase protein B. Lipid protein
C. Nucleocapsid protein. D. Glycoprotein E. Matrix protein
16. Sources of west nile disease virus in animals is the following: A. Mouse B. Horse C. Cow D. Deer E.Bird 17. Examination materials for the purpose of isolation virus from infected pigs suspected
Influenza is; A. Cloacal swabs B. Nasal mucus C. Blood D. Serum E. Faeces
18.Japanese encephalitis caused by: A. Alphavirus B. Flavivirus C. Herpesvirus D. Retrovirus E. Enterovirus 19.Characteristic of Enzootic Bovine leukosis is described bellow, except: A. Occurred in all sex and breed cows (beef and dairy) B. Common in dairy cattle than beef cattle C. Contagious for human D. Affected lymphoreticular system E. Disease characterized by persistent and malignant 20. Enzootic Bovine leukosis is caused by: A. Herpesvirus B. Coronavirus C. Rhabdovirus D. Enterovirus E. Retrovirus 21. Which of the symptoms are not for Aujeszky’s Disease A. Urticaria B. Paralyse of the pharynx C. pigs are the main host D. haemorrhagic diarrhea E. Affect animal become furious
22. The synonym of Pseudorabies is: A. Hog Cholera B. Lyssa C. Pseudoaphtae D. Pestis suum E. Aujeszky’s Disease 23. Transmision of Ebola disease is through:
A. Food C. Through drinks
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B. Secretion which contain Ebola virus D. Aerosol short distance E. Direct contact
24. The Ebola virus infects the cell via a specific protein that is A. Glycoprotein C. Matrix protein B. Nucleocapsid protein D. Ribonucleic protein E. Fusion proteins
25. Prevention of hantavirus disease can be done by means of vaccination with this type of vaccine, except A. Inacactivated vaccine C. DNA vaccines B. Recombinant vaccines with E coli D. Rodent brain derived E. Active vaccine
26. Which of the following Differential Diagnosis of Hog Cholera is false: A. Erysipelas B. Pseudorabies C. Foot and Mouth Disease D. Pasteurellosis E. Teschen Disease 27. Which of the folloving symptoms of Hog Cholera is false: A. Encephalitis B. Pneumonia C. Button ulcer on the colon mucosa D. Diarrhoea E. hemorrhages of serous membranes and subcutan 28. BEF can be diagnosed with these methode, except: A. SNT B. CFT C. FAT D. HA and HI-test E. Virus isolation and Identifikation
II. Answer the following questions by using the key below:
A. if only 1,2,3 are correct
B. if only I and 3 are correct D. if only 4 is correct
C. if only 2 and 4 are correct E. if all are correct 29. The most susceptible animal to Srapie is: 1. Cow 2. Goat 3. Buffalo 4. Sheep 30. The following disease is transmitted through mosquito bites: 1. BVD-MD 3. FMD 2. Rinderpest 4. Stomatitis vesikularis 31. The pathological changes caused by BVD-MD are: 1. Lymphoid tissue damage 3. Erosion and ulsera of the digestive tract 2. Balamitis 4. Encephalitis 32. Clinical manifestations of hantavirus infection in animal : 1. Hemorrhagic fever with renal syndrome 2. Nephropatia 3.pulmonary syndrome 4. Paralysa
33. Inoculation of this virus on the footpad cavia cause vesicula: 1. MCF 2. Stomatitis vesicularis 3. Rinderpest 4. FMD
34. Pathological changes caused by FMD virus : 1. Lymphoid tissue damage 3. Erosion and ulsera of the digestive tract 2. Encephalitis 4. Heart degeneration
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35. The following clinical symptoms seen in dog suffering of HCC: 1. Tonsils red and swollen 2.Abdomen pain 3. Edema in the head, abdomen and neck 4. Fever bifasis
36. Synonyms of distemper dogs are: 1. Maladie de care 2. Rubarth 3. Febrile catarrhalis infectiousa canis 4. Encephalitis wolf
37.Characteristic of HCC in dogs are describe bellow: 1. Presence of intranuclear inclusion bodies 2. Rapid course of the disease
3. Corneal opacity in one eye 4. Corneal opacity in both eyes 38. Animals are the most susceptible to Scrapie is:
1. Cow 2 goats 3. Buffalo 4. Sheep 39. This below which includes the properties of prions are: 1. Smaller than the virus 2. Not been characterized by complete 3. Infectious protein particles 4. Unstable 40. Accurate method that can be used to detect BSE is: 1.Immunohistochemistry 2. Western blotting 3. ELISA 4. CFT 41. This below that the general properties of the poxvirus are: 1. Survive for years in dust 2. Containing more than 30 different structural proteins 3. Replication intracytoplasmic 4. Not durable in dust 42. Blue Tongue disease transmission in goats mostly through below: 1. Culex mosquitoes 2. Mechanic 3 Ticks. 4. Lice 43. Specific clinical symptoms of blue tongue in infected animal is: 1. ulceration and lesions in the mouth 2 swollen tongue and cyanotic 3. Feet coronitis 4 feet lameness 44. Differences protein between influenza A virus and influenza B virus: 1.Protein M1 2. Protein H 3.Protein NP 4. Protein N 45. Protein involve in determination of Influenza A virus subtype: . 1. Protein M1 2. Protein H 3.Protein NP 4.Protein N 46. This serological test can be used to measure maternal antibody titre against parvovirus in dogs: 1. AGPT 2. HA test 3. FAT 4. HI test 47. The following symptoms appear in parvovirus infected puppies: 1. Vomiting 2. Corneal opacity 3. Diarrhea profus 4. Tic Convulsion 48. Venezuelan Equine Encephalitis has the following properties 1. High mortality 2. No death 3. Neurotrophic 4. Viscerotropic 49. Disease can be confused with Equine Encephalitis is: 1.Tetanus 2. Rabies 3. Botulismus 4. Japanese Encephalitis 50. Eastern Equine Encephalitis vectors are describe below : 1. Aedes 2. Mansonia 3. Culex 4. Culiseta melanura 51. Important variant of Equine Encephalitis virus which cause epizootic in America: 1. Subtype IA 2. Subtype IB 3 Subtype IC 4. Subtype II (Everglades) 52. Genital form of Infectious Pustular Vulvovaginitas accomplished by using the following . statement, except: 1. Ecephalitis 2. Genital mucous hyperemia with 1-2 mm vesicle
55. Characteristic of ebola disease in monkeys are marked by; 1. Bleeding 3. Abnormal blood coagulation 2 Paralysis 4. Profuse diarrhoe
56. Clinical symptoms in dogs and cats infected with west nile virus is ; 1. Fever, depression 3. Paralysis 2. Muscle weakness 4. Myocarditis
57. Desinfectant against contaminants pox virus that are either: 1. Sodium hipochloride 3. Detergent 2. Phenol 2% 4. Formalin 1%
58. Which of the following diseases is zoonotic: 1. Rabies 2. Pseudorabies 3. Food and Mouth Disease 4. Hog Cholera 59. Organs where Hog Cholera virus can be found are: 1. lymphnode of the respiratoric tract 2. leucocyte 3. intestine mucosa 4. Brain 60. To prevent Hog Cholera, piglets can be given: 1. Live vaccine 2. Killed vaccine 3. Combination of Antisera and live vaccine 4. Combination of Antisera and killed vaccine 61. Statement about Hog Cholera virus are are true: 1. Hog Cholera virus consist only one strain/serotype 2. can be ready inactivated by lipid solvent 3. cross reacted with Mucosal Disease virus 4. can be cultivated in chicken embrionated eggs by allantoic sac route 62. Characteristic for Bovine Ephemeral Fever are:
1. Transmitted by mosquitos 2. Morbidity rate great as 80% 3. Only cow and buffalo are affected 4. Can be transmitted by direct contact
63. Synonym of BEF is/are: 1. Three day sicknes 2. Bovine epizootic fever 3. Stiff sicknes 4. Bovine catarrhal fever
64. These animals can act as reservoir in Rabies: 1. Wolves 2. Horses 3. Vampire 4. Cows 65. The symptoms of Rabies which is often overlooked:
1. Paralytic 2. Prodromal
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3. Excitability 4. Behavior changes
III. ANSWER the following questions by using the key below: A. if both statement and reason are true and related cause and effect B. if both statement and reason are true but not related cause and effect C. if the statement is true but the reason is false D. if the statement is false but the reason is true E. if both statement and reason are false
66. Clinical symptoms of hantavirus infection is haemorrhagic fever accompanied by renal
syndrome BECAUSE hantavirus also cause pulmonary syndrome
67. During the incubation period of rabies virus infection, antibody responses were undetected, BECAUSE rabies virus spread to the CNS via nerve fibers.
68. Hantavirus if infects the cells do not cause cytopathic effect because hantavirus has persisten when infecting cells derived from mice (rodent)
69. Bovine Enzootic bovine leukosis common in mature cow, especially those in the culling,
BECAUSE Enzootic bovine leukosis not contagious for humans.
70. The first replication virus if infected with the smallpox virus in squamous epithelium, BECAUSE smallpox virus viremia occurred after multiple infections in the skin epidermis.
71. Cow pox can attack humans with clinical symptoms of pocks on hand BECAUSE, cow pox also attack cat with crater clinical symptoms like ulcers
72. Orf is a disease in sheep known as scabby mouth BECAUSE, ORF causes lesions on the lips of sheep and crusta
73. Renderpest disease is a differential diagnosis of Jembrana disease BECAUSE, renderpest disease and Jembrana diseases caused by viruses of the same group.
74. Blue tongue is a disease of ruminants as hospes primer is the goat, BECAUSE Blue tongue is an contagious disease of cattle, sheep and deer.
75. Eastern Equine Encephalitis virus is a member of the genus flavivirus BECAUSE, Japanese encephalitis virus is a member of the family Flaviviridae
76. Ebola disease known as haemorrhagic fever disease because ebola disease in addition to attack the hepatocytes cells also attack the endothelial cells
77 The Morbidity rate of BEF is low, BECAUSE BEF is transmited by mosquitos.
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78. Pseudorabies is also known as Mad Itch Disease, BECAUSE generally pigs infected with Pseudorabies shown CNS disorder.
79. Hantavirus can be secreted through excreta aerosol mice because hantavirus can be
horizontal transmited in mice 80. Hypersalivation can be seen in Dogs infected with Rabies virus, BECAUSE the replication
of Rabies virus take place in salivary gland
================== || ================
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MIDDLE SEMESTER EXAM INFECTIOUS DISEASE II (I.P VIRAL)
SEMESTER : IV
DAY / DATE :THURSDAY MARCH 29, 2018
TIME : 50 MINUTES
I. For each of the following multiple choice questions, choose the one most
appropriate answer:
1. Characteristic of rabies street strain virus are:
A. Highly virulent B. Cause Rabies in dogs
C. Highly variable of incubation period D. invade the salivary gland
E. All answer are true
2. Which of the following synonyms is not for rabies:
A. Hydrophobia B. Lyssa C. Penyakit anjing gila
D. Pseudorabies E. Tollwut
3. Clinical stadium of rabies as follows:
A. Convulsion B. Paralitic C. Furious
D. Prodromal E. All answer are true
4. Rabies caused by:
A. poxvirus B. Orthomyxo Virus C. Reovirus
D. Lyssavirus E. Coronavirus
5. Pathogenesis of the following disease involving antibody-dependent enhancement of
infection
A. Feline Infectious Peritonitis D. Feline Panleukopenia
B. Feline calici vinrs E. Coronavirus Canine Diarrhea
C. Feline Rhinotracheitis
6. Serologicaaly Canine Coronavirus Diarrhea is related to:
A. Canine Distemper D. Transmissible gastroenteritis
B. Canine Parvovirus E. Feline Rhinotracheitis
C. Feline Peritonitis lnfectious
7. Prevention of canine parvovirus in dogs can use a vaccine containing a virus:
A. Diarrhea Canine Coronavirus D. Feline Caliciviiuses
B. Canine Parainiluenza E. Feline parvovirus
C. Transinissible gastroenteritis
8. “Kennel Cough Syndrome" is often associated with virus infection :
A. Canine Distemper C. Paraintluenza Virus 1 E. Parainfluenza Virus 3
B. Canine Paiyovirus D. Parainfluenza Virus 2
9. “Shipping Fever" in cattle is often associated with viral infection ;
A. Influenza A C. Parainfluenza Virus l E. Parainfluenza Virus 3
B. Influenza B D. Paraintluenza Virus 2
10. The following symptoms may be observed in horses infected with influenza virus A,
except:
A. Conjunctivitas D. Red nose mucous
B. Increased body temperature E. Diarrhea
C. Cough
11. Effective serologic test for detection of maternal antibodies to parvovirus in puppies
A. HA B. HI C. CFT D. AGPT E. FAT
12. Ebola virus can infect animal with exception;
B. Gorillas B. Chimpanzees C. Antelop D. sheep E. Monkey
13. The specific binding receptor of ebola virus is;
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B. Nucleo protein B. Viral protein C. Glicoprotein D. viral protein30 (VP30)
F. Viral protein 40
14. Virological diagnosis of Equine Encephalitis can be done by:
A. virus Neutralization
B. HA test
C. Isolation of virus in the brains of mice and identification with the FAT
D. Polymerase Chain Polymerase (PCR)
E. nucleotide sequencing
15. The sensitivity of serological tests in the diagnosis of Equine Encephalitis are:
A. CFT> Test SN > HI Test
B. SN test> CFT.> HI test
C. HI Test> Test SN> CFT
D. HA Test> Test HI
E. PCR> Sequencing of nucleotides
16. Equine Encephalitis caused by a virus ;
A.The genus Alphavirus, Family Flaviviridae
B. Alphavirus genus, Togaviridae Family
C. Genus Flavivirus, Flaviviridae Family
D. Genus Flavivirus, Togaviridae Family
E. Genus Flavivirus, Family Adenoviridae
17. Host amplifier in the Japanese encephalitis is:
A. Horse B. Human C. Fowl D. Pig E. Bat
18. MCF is characterized by the following properties, except;
A. Caused by bovine herpes virus -3
B. Necrosis and lesions on the oral mucosa
C. Keratoconjunctivitis
D. Encephalitis
E. Blisters on the feet
19. An anthropod vector may be involved in its transmission of this disease :
A. MCF B. Foot and Mouth Disease C. Stomatitis Vesicularis
D. Exsanthema Vesicularis E. Pestis Suum
20. Leucopenia in blood tests can be found in an infected dog:
A. Diarrhea Canine Coronavirus D. Canine Parainfluenza
B. Canine Distemper E. Rabies
C. Canine Parvovirus
II. Answer the following questions by using the key below:
A. if 1,2,3 are correct
B. if 1 and 3 are correct D. if only 4 is correct
C. if 2 and 4 are correct E. if all are correct
28. The strategies of ebola virus infection by animal are
1. Binding attachment factor by receptor to pre membrane cell,
2. GP cleavage protein by cysteine proteases,
3. NPC1 binding with GP1alfa,
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4. Building viral nucleocapsid
29. Molecule substances, that can mediated of antibody dependent enhancement are;
43. Serotype of FMD can be detect by doing the test
1. ELISA 2. CFT 3. FAT 4. SNT
44. Epizootic cycle caused by ebola virus appear sporadically producing high mortality;
1. Non human primates 2. Precede human outbreaks 3. Acute disease
4. Transmission human to human
III. ANSWER the following questions by using the key below:
A. if both statement and reason are true and related cause and effect
B. if both statement and reason are true but not related cause and effect
C. if the statement is true but the reason is false
D. if the statement is false but the reason is true
E. if both statement and reason are false
49. Differential diagnosis of FMD is Stomatitis Vesicularis because SV and FMD caused
by the viruses of the same genus.
50. Ebola virus disease (formerly called Ebola Hemorrhagic disease) is a severe, often fatal,
disease in humans and non-human primates because ebola viruses have the ability to
turn internal organs into a soup that promptly flows out of the body.
51. The incubation period of Rabies are 14 days, because the migration time of the Rabies
virus to reach the central nervous system are fixed.
52. Rabies Fixed virus strain cannot be detect in the dog’s saliva, because the Rabies Fixed
virus strain migrate to the central nervous system by neurons.
49. Epizootic strains caused Equine Encephalitis more harm than Enzootic strain, because
The strain of enzootic of Epizootic Equine Encephalitis is a virus strain that has been
experienced in the natural attenuation.
50. Stomatitis vesikularis called Pseudo FMD because stomatitis vesikularis have clinical
symptoms similar aphthae Epizootika
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Final Semester Exam Infectious Viral Disease II (I.P. VIRAL) Faculty of Veterinary Medicine – Airlangga University Semester : IV Day/date : Thursday, 31 th May 2018 Time : 80 minutes_______________________________________________________ I. CHOOSE ONE OF THE MOST CORRECT ANSWER 1. Prevention of Hard Pad Disease in puppies can use vaccines containing viruses: A. CD B. Rinderpest C. Parvo Virus D. Feline Panleukopenia E. Hepatitis Contagiusa Canis 2. Causes of Hepatitis Contagiusa Canis in dogs: A. Orthomyxovirus B. Paramixovirus C. Pseudomyxovirus D. Parvovirus E. Adenovirus 3. Blue Tongue disease in the most dominant transmission sheep by vector: A. Flies B. Mosquito C. Tick D. Culex E. Ectoparasit 4. Distemper in young dogs show clinical symptoms below, Except: A. Bronchopneumonia B. Gastritis C. Tie convulsion D. Bloody Diarrhea E. Hepatitis 5. The following statements are about jembrana disease, Except: A. Attack Bali cattle B. Caused by Ricketsia C. There is enlargement and swelling of the lymph nodes and spleen D. There are clinical symptoms of hypersalivation and blood diarrhea E. Transmitted by arthrpoda vector 6. The following statement is about MCF disease: A. The cause is Picornavirus B. Occurrence of erosion lesions in the oral cavity and scrambled C. The causative virus has an antigenic relationship with the suum pestis D. Clinical symptoms include nephephalitis E. Viruses can be grown on TAB 7. The following statement is character of BVD-MD, except: A. Caused by Arbotogavirus B. Can be adapted on pig kidney cell C. Certain serotype can be aglutinate erythrocytes D. Can be cultivated in embryonated egg E. There is antigenic relationship with pestis suum 8. Leucopenia in blood examination was found in; A. Rinderpest D. Jembrana B. MCF E. FMD C. BVD-MD 9. The spread of west nile virus in animals is through vectors: A.Culex sp D. Anopheles sp B. Aides Aegypty E. Stomoxys Calsitrans C. Aides Albopicus
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10. The laboratory diagnosis of west nile virus infected animal is the following methods: A. PCR B. ELISA C. CFT D. AGPT E. HA-HI 11. This viral infections play a role within "Kennel Cough Syndrome" in dog: A. Parainfluenza virus 1 B. Parainfluenza virus 2 C. Parainfluenza virus 3 D. Influenza A E. Influenza B 12. "Shipping Fever" is often associated with : A. Parainfluenza virus 1 B. Parainfluenza virus 2 C. Parainfluenza virus 3 D. Sendai virus E. Simian virus 5
13. Bacterial infection that often as a secondary infection in Canine Distemper : A. Salmonella B. Pasteurella C. Mycoplasma D. Ecoli E. Bordetella bronchoseptica
14. The presence of leukopenia in blood examination of dog indicates an infection: A. Canine Coronavirus Diarrhea B. Canine Distemper C. Canine Parainfluenza D. Canine Parvovirus E. HCC
15. Protein that has important function when hantavirus infects a cell is :
A. Polymerase protein B. Lipid protein
C. Nucleocapsid protein. D. Glycoprotein E. Matrix protein
16. Sources of west nile disease virus in animals is the following: A. Mouse B. Horse C. Cow D. Deer E.Bird 17. The presence of fluid accumulation of yellow ascites (containing high concentrations of
protein, sometimes fibrin) is one indication of infected cats: A. Feline Calicivirus B. Feline Infectious Peritonitis C. Feline Rhinotracheitis D. Feline Panleukopenia E. Feline Parvovirus
18.Japanese encephalitis caused by: A. Alphavirus B. Flavivirus C. Herpesvirus D. Retrovirus E. Enterovirus 19.Characteristic of Enzootic Bovine leukosis is described bellow, except: A. Occurred in all sex and breed cows (beef and dairy) B. Common in dairy cattle than beef cattle C. Contagious for human D. Affected lymphoreticular system E. Disease characterized by persistent and malignant 20. Enzootic Bovine leukosis is caused by: A. Herpesvirus B. Coronavirus C. Rhabdovirus D. Enterovirus E. Retrovirus 21. Which of the symptoms are not for Aujeszky’s Disease A. Urticaria B. Paralyse of the pharynx C. pigs are the main host D. haemorrhagic diarrhea E. Affect animal become furious
22. The synonym of Pseudorabies is: A. Hog Cholera B. Lyssa C. Pseudoaphtae D. Pestis suum E. Aujeszky’s Disease
34
23. Here is the nature of rinderpest disease, Except: A. Clinical symptoms include bloody diarrhea B. The virus has an antigenic relationship with distemper and measles C. Virus can be adapted to TAB D. High mortality E. Caused by herpetoviridae virus 24. The following is about FMD, Except: A. Clinical Symptoms of hypersalivation and lameness B. Caused by picornavirus C. Cause high economic losses D. High mortality E. There are serotypes such as A, O, C 25. Prevention of hantavirus disease can be done by means of vaccination with this type of
vaccine, except A. Inacactivated vaccine C. DNA vaccines B. Recombinant vaccines with E coli D. Rodent brain derived E. Active vaccine
26. Correct statement about the disease Bovine Ephemeral Fever: A. Horses can not be infected B. is transmitted through saliva C. mortality can reach 80% D. Nerve abnormalities result in paralysis E. There are blisters on the mucosa of the lips and tongue
27. Which of the folloving symptoms of Hog Cholera is false: A. Encephalitis B. Pneumonia C. Button ulcer on the colon mucosa D. Diarrhoea E. hemorrhages of serous membranes and subcutan 28. BEF can be diagnosed with these methode, except: A. SNT B. CFT C. FAT D. HA and HI-test E. Virus isolation and Identifikation
II. Answer the following questions by using the key below:
A. if only 1,2,3 are correct
B. if only I and 3 are correct D. if only 4 is correct
C. if only 2 and 4 are correct E. if all are correct 29. The most susceptible animal to Srapie is: 1. Cow 2. Goat 3. Buffalo 4. Sheep 30. The following disease is transmitted through mosquito bites: 1. BVD-MD 3. FMD 2. Rinderpest 4. Stomatitis vesikularis 31. The pathological changes caused by BVD-MD are: 1. Lymphoid tissue damage 3. Erosion and ulsera of the digestive tract 2. Balamitis 4. Encephalitis
35
32. Clinical manifestations of hantavirus infection in animal : 1. Hemorrhagic fever with renal syndrome 2. Nephropatia 3.pulmonary syndrome 4. Paralysa
33. Inoculation of this virus on the footpad cavia cause vesicula: 1. MCF 2. Stomatitis vesicularis 3. Rinderpest 4. FMD
34. Pathological changes caused by FMD virus : 1. Lymphoid tissue damage 3. Erosion and ulsera of the digestive tract 2. Encephalitis 4. Heart degeneration
35. Characteristic of HCC: 1. Inflammation of the liver 2. Cloudy corneas on both eyes 3. Inclusion of the intranuclear 4. Low mortality 36. The following clinical symptoms are typical symptoms of orf disease: 1. Lesions on the nose 2. Ear lesions 3. Lesions on the vulva 4. Blue tongue 37. Typical HPD are: 1. Inclusion of intrasitoplasmic body 2. Bifasis fever 3. Inflammation of the liver 4. Hyperkeratosis 38. Animals are the most susceptible to Scrapie is:
1. Cow 2 goats 3. Buffalo 4. Sheep 39. This below which includes the properties of prions are: 1. Smaller than the virus 2. Not been characterized by complete 3. Infectious protein particles 4. Unstable 40. Accurate method that can be used to detect BSE is: 1.Immunohistochemistry 2. Western blotting 3. ELISA 4. CFT 41. This below that the general properties of the poxvirus are: 1. Survive for years in dust 2. Containing more than 30 different structural proteins 3. Replication intracytoplasmic 4. Not durable in dust 42. The following clinical symptoms are seen in distemper dogs 1. Respiration 2. Digestion 3. Neurology 4. Fever is based 43. Specific clinical symptoms of blue tongue in infected animal is: 1. ulceration and lesions in the mouth 2 swollen tongue and cyanotic 3. Feet coronitis 4 feet lameness 44. Samples used for the purpose of virus isolation from chickens infected with avian
influenza: 1. Swab trachea 2. Blood 3. Swab Cloaca 4. Serum 45. Interstitial pneumonia in cattle due to parainfluenza infection 3 often accompanied by viral I Infection: 1. Virus adeno 2. IBR virus 3. Bovine respiratory syncytial virus 4. Virus rinderpest 46. Differences between influenza A and B viruses are present in proteins: 1. Protein H 2. Protein NP 3. Protein N 4. Protein M 47. The following symptoms appear in parvovirus infected puppies: 1. Vomiting 2. Corneal opacity 3. Diarrhea profus 4. Tic Convulsion 48. Venezuelan Equine Encephalitis has the following properties
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1. High mortality 2. No death 3. Neurotrophic 4. Viscerotropic 49. Disease can be confused with Equine Encephalitis is: 1.Tetanus 2. Rabies 3. Botulismus 4. Japanese Encephalitis
50. Eastern Equine Encephalitis vectors are describe below : 1. Aedes 2. Mansonia 3. Culex 4. Culiseta melanura 51. Important variant of Equine Encephalitis virus which cause epizootic in America: 1. Subtype IA 2. Subtype IB 3 Subtype IC 4. Subtype II (Everglades) 52. Genital form of Infectious Pustular Vulvovaginitas accomplished by using the following . statement, except: 1. Ecephalitis 2. Genital mucous hyperemia with 1-2 mm vesicle 3. Red nose 4. Balanophostitis 53. Differential diagnosis of Infectious Bovine Rhinotracheitis are: 1. Enzootic bronchopneumonia 2. Bovine Viral Diarrhea (BVD) / mucosal disease (MD) 3. Gangrenous coryza 4. Rinderpest
55. Characteristic of ebola disease in monkeys are marked by; 1. Bleeding 3. Abnormal blood coagulation 2 Paralysis 4. Profuse diarrhoe
56. Clinical symptoms in dogs and cats infected with west nile virus is ; 1. Fever, depression 3. Paralysis 2. Muscle weakness 4. Myocarditis
57. Desinfectant against contaminants pox virus that are either: 1. Sodium hipochloride 3. Detergent 2. Phenol 2% 4. Formalin 1%
58. The following diseases in Indonesia are: 1. Three Days Fever 2. Rinderpest 3. Pseudorabies 4. Mouth and Nail Disease
59. Bovine Ephemeral Fever Transmission Can occur through: 1. orally 2. per inhalation 3. fecal-oral route 4. mosquito bites
60. To prevent Hog Cholera, piglets can be given: 1. Live vaccine 2. Killed vaccine 3. Combination of Antisera and live vaccine 4. Combination of Antisera and killed vaccine 61. Statement about Hog Cholera virus are are true: 1. Hog Cholera virus consist only one strain/serotype 2. can be ready inactivated by lipid solvent
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3. cross reacted with Mucosal Disease virus 4. can be cultivated in chicken embrionated eggs by allantoic sac route 62. Characteristic for Bovine Ephemeral Fever are:
1. Transmitted by mosquitos 2. Morbidity rate great as 80% 3. Only cow and buffalo are affected 4. Can be transmitted by direct contact
63. Synonym of BEF is/are: 1. Three day sicknes 2. Bovine epizootic fever 3. Stiff sicknes 4. Bovine catarrhal fever
64. These animals can act as reservoir in Rabies: 1. Wolves 2. Horses 3. Vampire 4. Cows 65. The symptoms of Rabies which is often overlooked:
III. ANSWER the following questions by using the key below: A. if both statement and reason are true and related cause and effect B. if both statement and reason are true but not related cause and effect C. if the statement is true but the reason is false D. if the statement is false but the reason is true E. if both statement and reason are false
66. The dog recovered from HPD will be immune to CD BECAUSE as the HPD virus has the
same antigenicity as the CD virus
67. During the incubation period of rabies virus infection, antibody responses were undetected, BECAUSE rabies virus spread to the CNS via nerve fibers.
68. Active parvovirus vaccine should not be administered to a pregnant cat BECAUSE as an active vaccine contains an adjuvant
69. Bovine Enzootic bovine leukosis common in mature cow, especially those in the culling,
BECAUSE Enzootic bovine leukosis not contagious for humans.
70. The first replication virus if infected with the smallpox virus in squamous epithelium, BECAUSE smallpox virus viremia occurred after multiple infections in the skin epidermis.
71. Cow pox can attack humans with clinical symptoms of pocks on hand BECAUSE, cow pox also attack cat with crater clinical symptoms like ulcers
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72. Orf is a disease in sheep known as scabby mouth BECAUSE, ORF causes lesions on the lips of sheep and crusta
73. The differential diagnosis of Orf is blu tongue disease BECAUSE The two diseases are similar
74. Blue tongue is a disease of ruminants as hospes primer is the goat, BECAUSE Blue tongue is an contagious disease of cattle, sheep and deer.
75. Eastern Equine Encephalitis virus is a member of the genus flavivirus BECAUSE, Japanese encephalitis virus is a member of the family Flaviviridae
76. Blue tongue disease is caused by the family reoviridae virus and has blue tongue symptom. BECAUSE The blue tongue virus has 24 serotypes
77 The Morbidity rate of BEF is low, BECAUSE BEF is transmited by mosquitos. 78. Pseudorabies is also known as Mad Itch Disease, BECAUSE generally pigs infected with
Pseudorabies shown CNS disorder. 79. Hantavirus can be secreted through excreta aerosol mice because hantavirus can be
horizontal transmited in mice 80. Hypersalivation can be seen in Dogs infected with Rabies virus, BECAUSE the replication