Physiologic correlation • Boyle's Law P.V = K • Hooke's Law ΔL αΔT • Laplace's Law ΔP = 2.T/r • Poiseuille's Law R = 8.L.eta/(pi.r 4 ) • The Fanning Equation ΔP α 1/r 5 • Fick's Law Vgas α A*ΔP/L • Graham's Law D α sol / MW 0.5 • Charles' Law V = K'. T a b c d d
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α Physiologic correlation - medinfo2.psu.ac.thmedinfo2.psu.ac.th/pr/chest2012/chest2010/pdf/[12] Cases with physiologic correlation... · Morphology Physiology Physiology of lung
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Physiologic correlation
• Boyle's Law P.V = K • Hooke's Law ΔL α ΔT • Laplace's Law ΔP = 2.T/r• Poiseuille's Law R = 8.L.eta/(pi.r4)• The Fanning Equation ΔP α 1/r5
• Fick's Law Vgas α A*ΔP/L• Graham's Law D α sol / MW0.5
• Charles' Law V = K'. T
a
b
cd
d
MorphologyPhysiology
Physiology of lung
1. Perfusion, Q2. Ventilation, V3. Lymph flow, L4. Stress or Strain, S
Relate with gravity.Upper and lower portions are different.
• Vertical physiology• Axial physiology• Physiology of the secondary pulmonary
lobule
Cross-sectional imagingVertical physiology
Vertical Physiology
• Upper lobe predominant:Tbc, Silicosis and Sarcoidosis
-Particles finally goes to cortex.-Diseases can appear at anywhere.-Immune-activated chronic inflammation trends to remain at lower, dorsal cortex.-Residuals from immune clearance remain in upper, dorsal medulla.-Cavities trend to appear in peripheral upper.-Physiologic correlation can be better appreciated with CT.