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Page 8
List of Publication of Professor Rafat M. Mohareb
1- Activated Nitriles In Heterocyclic Synthesis: A Novel Synthesis of
Pyrimidine, Pyridine and Isoxazole Derivatives.
S. M. Fahmy, N. M. Abed, R. M. Mohareb and M. H. Elnagdi;
Synthesis 6, 490 (1982).
2- Activated Nitriles In Heterocyclic Synthesis: A Novel Synthesis of
Tetrazole Derivatives.
S. M. Fahmy and R. M. Mohareb; Synthesis 6, 478 (1983).
3- Activated Nitriles In Heterocyclic Synthesis: Synthesis of Several
New Pyrimidine and Pyridazine Derivatives.
K. U. Sadek, S. M. Fahmy, R. M. Mohareb and M. H. Elnagdi; J.
Chem. Engin. Data 29, 101 (1984).
4- Activated Nitriles In Heterocyclic Synthesis: A Novel Synthesis of
Polyfunctionally Substituted Pyridine Derivatives.
S. M. Fahmy, S. O. Abd Allah and R. M. Mohareb; Synthesis 11,
976 (1984).
5- Activated Nitriles In Heterocyclic Synthesis: A Novel Synthesis of
Pyridine and Pyridazine Derivatives.
S. M. Fahmy and R. M. Mohareb; Synthesis, 1135 (1985).
Page 9
6- Activated Nitriles In Heterocyclic Synthesis: A Novel Synthesis of
Pyridazine, Pyrimidine, Pyridine and Pyrano[4,3-b]pyridine
Derivatives.
R. M. Mohareb and S. M. Fahmy; Zeitschrift. Fur Naturforschung
40b, 664 (1985).
7- Oxonitrile In Heterocyclic Synthesis: Some New Approaches for
the Synthesis of Pyridazine and Pyrido[2,3-d]pyridazine
Derivatives.
S. M. Fahmy and R. M. Mohareb; Leibigs Ann. Chem., 1492
(1985).
8- Reaction of Malononitrile and Ethyl Cyanoacetate: A Novel
Synthesis of Polyfunctionally Substituted Pyridine Derivatives.
R. M. Mohareb and S. M. Fahmy; Zeitschrift fur Naturforschung
40b, 1537 (1985).
9- Cyanothioacetamide In Heterocyclic Synthesis: A Novel Synthesis
of 2-Pyridothione Derivatives.
S. M. Fahmy and R. M. Mohareb; Tetrahedron, 41 (2), 687 (1986).
10- Cyanothioacetamide In Heterocyclic Synthesis: A New
Approaches for the synthesis of Pyridothione, Pyrane and
Pyridazine Derivatives.
R. M. Mohareb and S. M. Fahmy; Zeitschrift. Fur Naturforschung,
41b, 105 (1986).
11- Dimerized Ethyl Cyanoacetate In Heterocyclic Dye
Synthesis:
Page 10
New Pyridine Azodye and tetrazole Dyes.
S. M. Fahmy, R. M. Mohareb and F. A. Abd El-Aal; J. Chem.
Tech.
And Biotechnol. 36, 410 (1986).
12- Polyfunctionally Substituted Pyridines from Cyanoacetamide and
Cyanoacetanilide.
R. M. Mohareb, A. Habashi, H. Z. Shams and S. M. Fahmy; Arch.
Die Pharm. (Weinheim) 320, 599 (1987).
13- Reactions With Acetoacetanilide: New Approaches for the
Synthesis of Polyfunctionally Substituted Pyridine Derivatives.
A. Habashi, N. S. Ibrahim, R. M. Mohareb and S. M. Fahmy;
Leibigs
Ann. Der Chemie 1632 (1986).
14- Nitriles In Heterocyclic Synthesis: New Approaches for the
Synthesis of Pyrazoles, Isoxazoles and Pyrimidines.
N. S. Ibrahim, A. A. Hafez and R. M. Mohareb; Heterocycles, 243,
2085 (1986).
15- The chemistry and Synthetic Potentialities of β-Ketoanildes:
Reaction of Ethyl Cyanoacetate with β-Ketoanilides.
A. Habashi, N. S. Ibrahim, S. M. Sherif, H. Z. Shams and R. M.
Mohareb; Heterocycles 24, 2463 (1986).
16- The Synthetic Potentialities of Nitriles In Heterocyclic
Synthesis.
Page 11
M. H. Elnagdi, S. M. Sherif and R. M. Mohareb; Heterocvycles,
26, 497 (1987).
17- Reaction of Benzoyl Isothiocyanate with Active Methylene
Reagents: A convenient Synthesisd of Pyrazolo[5,4-c]pyrazole, 1,3-
Oxazine, Thiazole and Pyrimidine Derivatives.
R. M. Mohareb, A. Habashi, N. S. Ibrahim and S. M. Sherif;
Synthesis, 3, 228 (1987).
18- α-Haloketoximes In Heterocyclic Synthesis: Polyfunctionally
Substituted Azoles and Azines from Bromoketoximes.
R. M. Mohareb, A. Habashi, E. A. Hafez and S. M. Sherif; Arch.
Die Parm. (Weinheim), 320, 776 (1988).
19- Nitriles In Heterocyclic Synthesis: A new Approaches for
The Synthesis of Thiazoles Derivatives.
N. S. Ibrahim, R. M. Mohareb and M. H. elnagdi; J. Fur Prakt.
Chem. 330, 65 (1988).
20- Nitriles In Heterocyclic Synthesis: 1-Cyanoformamide as a
Precursor for a Variety of Heterocyclic Ring Systems.
S. M. Sherif, R. M. Mohareb, G. E. Elgemeie and R. P. Singh;
Heterocycles, 27, 1579 (1988).
21- Nitriles In Heterocyclic Synthesis: New Approaches For the
Synthesis of Some Pyridine Derivatives.
N. S. Ibrahim, R. M. Mohareb and H. Z. Shams; Zeitschrift. Fur
Naturforschung (1988).
Page 12
22- The Knoevenagel Reaction of Cyanoacetamide with β-
Ketoanilides: Synthesis of Polyfunctionally Substituted pyridine and
Coumarine Derivatives.
R. M. Mohareb and N. S. Ibrahim; J. fur Prak. Chemie, 331, 367
(1989).
23- One Pot Synthesis of Polyfunctionally Substituted 2,3-
Dihydrothiazoles and Thiazolidines.
R. M. Mohareb, S. M. Sherif, A. A. Abdel-Aal, N. I. A. Sayed;
Leibigs Ann. Der Chemie, 1143 (1990).
24− ω-Bromoacetophenone In Heterocyclic Synthesis: A Convenient
One-pot Synthesis and the Chemical Behaviour of 3-
Bromomethylbenzo[d]isoxazole.
R. M. Mohareb, S. M. Sherif, H. Z. Shams and A. M. El-
Torgoman;
Z. Naturforsch., 45b, 1067 (1990).
25- Heterocyclic Synthesis with Isothiocyanates: Synthesis of
Several
New Polyfunctionally Substituted Thiophene, Thiazole and
Thiazolinone Derivatives.
R. M. Mohareb and S. M. Sherif; Arch. Die Pharm.
(Weinheim),
324, 469 (1991).
26- Reactions With 4-Phenyl-3-thiosemicarbazides: A new
Approaches for the Synthesis of Pyrazole, Thiazole, Pyridine and
Page 13
Pyrido[3,4-b]pyridine Derivatives.
R. M. Mohareb, S. I. Aziz and I El-Sakka; Sulfur Letters, 13
(5) , 299 (1991).
27- A Convenient One-Step Synthesis of Thiophene, Thieno[3,2-
b]pyridazine, Thieno[3,2-b]pyridine and Thiazole Derivatives.
R. M. Mohareb, S. I. Aziz; Sulfur Letters, 13 (5), 229 (1991).
28- y-Bromoacetoacetanilide In Heterocyclic Synthesis: A
Convenient Synthesis of Polyfunctionally Substituted 2,3-
Dihydrothiazole, Pyridine-2-one, 1,2,3-Thiazine, Oxazolo[3,4-
b]pyridine and Pyrazolo[3,4-b]pyridine Derivatives.
R. M. Mohareb, N. I. Abdel-Sayed and S. M. Sherif;
Phosphorous, Sulfur and Silicon, 63, 119 (1991).
29- The Knoevenagel Reaction of Malononitrile with
Acetylacetone:
New Route of Pyrazole, Pyrazolo[2,3-c]pyridine, Benzene,
Pyridazine and Benzo[c]pyridazine Derivatives.
R. M. Mohareb; Arch. Pharm. Res. 14 (4), 379 (1991).
30- Studies With Polyfunctionally Substituted Pyridazines:
Synthesis of new 4-Coumarin-3-yl-pyridazines.
R. M. Mohareb, H. Z. Shams and M. H. Elnagdi; Gazzeta
Chimica Ital., 122, 41(1992).
31- Phenylisothiocyanate In Heterocyclic Synthesis: Novel
Synthesis of Thiazoles, Thieno[2,3-b]pyridine, Thiophene and
Thieno[3,2-c]pyridazine Derivatives.
Page 14
R. M. Mohareb; Monatschfte fur Chemie, 123, 341 (1992).
32- One-Pot Synthesis of polyfunctionally Substituted Thiophenes,
Thieno[3,4-d]pyridine Derivatives.
R. M. Mohareb; Gazzetta Chemica Ital., 122, 147 (1992).
33- Novel Synthesis of Coumarin-3-yl-1,3-thiazole, 2-(Coumarin-
3-carbonyl)-thieno[2,3-b]pyridine and 2-(Coumarin-3-carbonyl)-
thiophene Derivatives.
R. M. Mohareb, H. Z. Shams and S. I. Aziz; J. Chem. Research
(S), 154 (1992), (M), 1132 (1992).
34- Reactions of Phenyl Isothiocyanate and Sulfur With Dimeric
Adducts: Novel Synthesis of Thiazoles, Thiazolo[4,5-
d]pyrimidine and Thiazolo[4,5-d]pyridine Derivatives.
R. M. Mohareb, H. Z. Shams and Y. M. El-Kholy;
Phosphorous, Sulfur and Silicon, 70, 317 (1992).
35- Heterocyclic Synthese With Isothiocyanates: A Novel
Synthetic Approach to Polyfunctionally Substituted Pyrazoles
and Their Fused Derivatives.
R. M. Mohareb and S. M. Sherif, Sulfur Letters, 15 (1), 91
(1992).
36- The Uses of Ethyl Cyanobromoacetate In Heterocyclic
Synthesis:
Novel Synthesis of Thiophene, Pyrazolo[3,4-d]thiazole and
thieno[2,3-d]pyridazine Derivatives.
R. M. Mohareb, S. El-Kousy and A. M. El-Torgoman; Collect.
Page 15
Czech. Chem. Commun. 57, 1747 (1992).
37- Novel Synthesis of 4-Bromo-3-oxo-2-phenylhydrazonobutro-
nitrile and 4-Cyano-3-oxo-2-phenylhydrazonobutyronitrile:
Synthesis of Pyridazine, Thiazole, 1,2,4-Triazine and
Pyrido[2,3-e]-1,2,4-triazine Derivatives.
R. M. Mohareb and N. I. A. El-Sayed; Collect. Czech. Chem.
Commun. 57, 1758 (1992).
38- Reactions of Benzoyl Isothiocyanate With Active Methylene
Reagents: A Novel Synthesis of Thiophene, Thiazoline and
Thieno[2,3-d]pyrimidine Derivatives.
R. M. Mohareb, S. I. Aziz, N. I. El-Sayed and H. Z. Shams;
Chin. Chem. Soc., 39, 181 (1992).
39- The Uses of 4-Phenyl-3-Thiosemicarbazide In Heterocyclic
Synthesis.
R. M. Mohareb, H. Z. Shams and Y. M. Elkholy; Phosphorous,
Sulfur and Silicon, 72, 93 (1992).
40- Studies With Alkylheteroaromatic Carbonitrile: Synthesis of
New Mesoionic Pyridazines, Phthalazines and Thienopyridazines.
R. M. Mohareb, A. M. El-Torgoman, S. I. Aziz, S. M. El-Kousy
and M. Riad; Gazzetta Chimica Ital. 122, 503 (1992).
41- Reactions of Benzoylisothiocyanate With Acetoacetanilide:
Synthesis of Pyrrole, Pyridine, Pyrimidine, Pyrazolo[3,4-
d]pyrimidine, Pyrazolo[3,4-d]pyrimidine, Pyrano[4,3-
d]pyrimidine and Pyrido[4,3-d]oxazine Derivatives.
Page 16
R. M. Mohareb, S. I. Aziz, N. I. A. El-Sayed and F. Z. Elablak;
Collection Czech. Chem. Commun., 58, 947 (1993).
42- Heterocyclic Synthesis With Enamines: Convenient Syntheses
of Polyfunctionally Substituted Pyrazole, Pyridine, Pyrimidine
and Pyrazolo[3,4-d]pyrimidine Derivatives.
R. M. Mohareb, S. M. Sherif and H. F. Zohdi, J. of The Chin.
Chem. Soc., 40, 181 (1993).
43- Heterocyclic Dye Synthesis: Synthesis and Dyeing
Performance of New Polyfunctional Pyridine Azodye.
R. M. Mohareb, S. M. Sherif and H. Z. Shams; A. Dyest. Rep.,
82(5), 37, 52-53 (1993).
44- Heterocyclic Synthesis With Isothiocyanate: An Expecditious
Synthetic Route to Polyfunctionally Substituted Thiophene,
Pyrazole, Oxazole, 2,3-Dihydrothiazole, 2-(Pyrazol-4-
ylideno)thiazole and 5-(thiazol-2-ylideno)-pyrimidine
Derivatives.
S. M. El-Kousy, R. M. Mohareb and S. M. Sherif; J. Chem.
Research (S), 312 (1993), (M), 1981 (1993).
45- Studies With Polyfunctionally Substituted Heteroaromatic: A
New Route to Polyfunctionally Substituted Mercapto-
phthalazines.
M. H. Elnagdi, R. M. Mohareb, F. A. Abdel-Aal and H. A.
Mohamed, Phosphorous, Sulfur & Silicon, 82, 195 (1993).
46- Heterocyclic Synthesis With Isothiocyanate: An Expeditious
Page 17
Synthetic Route for Polyfunctionally Substituted 3-(Thiazol-2’-
ylidene)pyridines and their Fused Derivatives.
R. M. Mohareb, H. F. Zohdi, S. M. Sherif and W. W.
Wardakhan; Tetrahedron, 50, 5807 (1994).
47- The Reaction Of Active Methylene Reagents With Sulfur and
Phenyl Isothiocyanate: Novel Synthesis of Thiazole,
Thiazolo[4,5-d]pyrimidine and 4,5’-Bithiazolyl Derivatives.
R. M. Mohareb, W. W. Wardakhan and F. Z. El-Ablack; J.
Chem. Research (S), 126 (1994); J. Chem. Research (M), 0747
(1994).
48- The Reaction of 4-Phenyl-3-Thiosemicarbazide with β-
Bifunctional Compounds: Novel Synthesis of Pyridine and
Pyrazole Derivatives.
Y. M. Elkholy and R. M. Mohareb; Phosphorous, Sulfur &
Silicon, 90, 111 (1994).
49- The Reaction of Carbon Disulphide with 2-Aminoprop-1-ene,
1,1,3-tricarbonitrile: One-Pot Synthesis of thiophenes and their
Fused Derivatives.
R. M. Mohareb and S. M. Sherif; J. Chem. Research (S), 484
(1994).
50- Reaction of Carbon Disulphide With Diethyl 3-Amino-2-
Cyano-2-penten-1,5-Dicarboxylate: A Convenient Synthesis of
Polyfunctionally Substituted Thiophenes and Their Fused
Derivatives.
S. M. Sherif, N. I. Abdel-Sayed, S. M. El-Kousy and R. M.
Page 18
Mohareb; Monatshefte fur Chemie, 126, 601 (1995).
51- Heterocyclic Synthesis With Isothiocyanate and Sulfur: A
Novel Synthesis of Pyrido[2,3-d]thiazole,
thiazolo[4’,5’:2,3]Pyridino[4,5-d]pyridazine and Thiazolo[4,5-
b]isoquinoline Derivatives.
H. Z. Zohdi, R. M. Mohareb and W. W. Wardakhan;
Phosphorous, Sulfur & Silicon, 101, 179 (1995).
52- Heterocyclic Synthesis With Isothiocyanates: A Convenient
Synthesis of Polyfunctionally Substituted 2,3-Dihydrothiazole,
2-(Pyrazol-4’-yl)-Thaizole, 5-(Thiazol-2’-yl)pyrimidine and
Thiazolo-[3,2-a]pyridine Derivatives.
R. M. Mohareb, S. M. Sherif and A. M. Sami; Phosphorous,
Sulfur & Silicon, 101, 57 (1995).
53- Reaction of Carbon Disulphide With Active Methylene
Reagents:
Novel Synthesis of Thiophene, Thieno[2,3-b]thiophene,
Thieno[3,2-c]pyrazole and Thieno[3,2-b]pyridine Derivatives.
R. M. Mohareb, S. M. Sherif, A. Habashi, N. I. Abdel-Sayed
and S. S. Osman; Collect. Czech. Chem. Commun., 60, 1578
(1995).
54- The Uses of Polyfunctionally Substituted Thiophenes In
Heterocyclic Synthesis: Synthesis of Benzo[b]Thiophene,
Thieno[2,3-b]pyridine Derivatives.
R. M. Mohareb, Y. M. Elkholy and N. I. Abdel-Sayed;
Phosphorous, Sulfur & Silicon, 106, 193 (1995).
Page 19
55- Studies With Polyfunctionally Substituted Heteroaromatics: The
Reactivity of Alkylazoles Towards Electrophilic Reagents.
S. E. Zayed, S. I. Aziz, A. W. Erian, R. M. Mohareb, E. I. Abou
Elmaged, S. A. Metwally and M. H. Elnagdi; Phosphorous, sulfur
And Silicon, 102, 51 (1995).
56- A Convenient Synthesis of Polyfunctionally Substituted
Benzo[b]thiophen-2-yl-pyrimidine, pyrazole, isoxazole and pyridine
derivatives.
S. M. Sherif, R. M. Mohareb, H. Z. Shams and H. M. M.
Gaber; J. Chem. Res. (S), 434, (M) 2658 (1995).
57- The Reaction of 3-Phenyl-5-Aminopyrazole With Carbon
Disulphide: A Novel Synthesis of 3-(3’-phenylpyrazo-5’-yl)-4-
Phenylpyrazol-2-thione, Pyrazolo[3,4-d]thiazole and
Pyrano[2,3-d]thiazole Derivatives.
R. M. Mohareb, H. F. Zohdi and W. W. Wardakhan; Monatsh.
Fur Chem., 126, 1391 (1995).
58- Synthesis of Some New Thiazolines
S. M. Sherif and R. M. Mohareb, 5th, Ibn Siina International
Conference on Pure and Applied Heterocyclic Chemistry, PIP-22
(1995).
59- Studies with Polyfunctionally Substituted Heteroaromatics:
The Reactivity of Alkylazoles Towards Electrophilic Reagents.
S. E. Zayed, S. I. Aziz, A. W. Erian, R. M. Mohareb, E. A. El-
maged and M. H. Elnagdi, Phophorous, Sulfur & Silicon, 51,
Page 20
102 (1995).
60- β-Enaminonitrilers in Heterocyclic Sytnthesis: A Novel one-
pot Synthesis of Thiophenes and Their Fused Derivatives.
S. M. Sherif, W. W. Wardakhan and R. M. Mohareb; J. of
Chem. Research (S), 356 (1996), (M), 1970 (1996).
61- Convenient Heterocyclization Reactions With Ethyl 2-amino-
4,5,6,7-tetrahydrobenzo[b]thiophene-3-carboxylate: Synthesis of
Thiazole, Isoxazole, Pyrazole, Pyrimidine and Pyridazine
Derivatives.
H. F. Zohdi, W. W. Wardakhan, S. H. Doss and R. M.
Mohareb; J. of Chem. Research, (S), 440 (1996), (M) 2526
(1996)
62- Reaction of 4-Aryl-3-thiosemicarbazides with Carbon
Disulphide: A Facile Convenient Synthesis of 2,3-
Dihydrothiazoles and their Fused Derivatives.
R. M. Mohareb and S. M. Sherif; J. Heteroatom, 77, 8 (1997).
63- The Uses of 4-Aryl-3-thiosemicarbazide In Heterocyclic
Synthesis: Synthesis of Coumarin, Pyrazole, Thiazole and
Thiophene Derivatives.
R. M. Mohareb, S. S. Ghabrial and W. W. Wardakhan,
Phosphorous, Sulfur & Silicon 134, 119 (1998).
64- Studies
With Polyfunctionally Heteroaromatic Compounds: Synthesis of
Page 21
Some New Polyfunctionally Substituted Pyrido[3,2-c]pyridines
and Pyrido[2,3-c]pyridazines.
S. M. El-Kousy, R. M. Mohareb, M. Raid and M. H. Elnagdi,
Pak. J. Sci. Ind. Res. 41(20, 81-85 (1998).
65- Reaction of 4-Aryl-3-thiosemicarbazide With Phenylisothio-
cyanate: Synthesis of Thiazole, Pyrazole and Pyrimidine
Derivatives.
R. M. Mohareb, W. W. Wardakhan and D. Fleita; J. Chinese
Chemical Society 46, 97 (1999).
66-Synthetic Potentialities of Thiophene In Heterocyclic Synthesis:
A Novel Synthesis of Thieno[2,3-b]pyridine Derivatives.
R. M. Mohareb, H. Z. Shams, Y. M. El-Khooly and R. Azzam
Phosphorous, Sulfur & Silicon 155, 215 (1999).
67-The Reaction of Cyanoacetic acid Hydrazide With Phenyliso-
Thiocyanate.
R. M. Mohareb, S. I. Aziz, N. I. Abdel-Sayed and A. A.
Elbanna
J. of Chemical Research (S), 10 (1999) & (M) 0101, 0128
(1999).
68- Sultamo-Steroid Analogues Part VII: Synthesis of
Epiandrosterons With Potential Activities.
S. H. Doss, R. M. Mohareb, N. A. Lucca and G. A. Elghany,
Arch. Pharmazie 22, 496 (1999).
Page 22
69- Sudies of The Synthesis of Chiral nonracemic 3,4-disubstituted
Azepanes, a Formal Synthesis of (+) and (-) Balanol Derivatives.
C. Herdeis, R. M. Mohareb, B. R. Neder and T. F.
Schwabenlander; Tetrahedron Asymmetry 10 (23), 4521
(1999).
70- Reaction of Ethyl 2-Diazo-4,5,6,7-Tetrahydrobenzo[b]-
thiophene 3-Carboxylate With Benzoyl Acetonitrile: Synthesis
of Pyrazoles, Pyridazines, Pyrimidines and Their Fused
derivatives.
R. M. Mohareb, M. H. Mohamed and W. W. Wardakhan;
Phosphorous, Sulfur & Silicon, 167 29 (2000).
71-Reaction of 2-Diazo-4,5,6,7-Tetrahydrobenzo[b]thiophene-3-
Carboxylate With 3-Iminobutyronitrile: Synthesis of Thiophene
and Their Fused Derivatives.
R. M. Mohareb and F. M. Manhi; Heteroat. Chem. 11(6), 403
(2000).
72-The Reaction of 2-Amino-3-Cyano-4,5,6,7-Tetrahydrobenzo-
[b]-Thiophene with Diethyl Malonate: Synthesis of Coumarin,
Pyridine and Thiazole Derivatives.
R. M. Mohareb, F. A. El-Omran and J. Ho; Heteroat. Chem.
12(3), 168 (2001).
73- The Reaction of 2-Amino-3-Cyano-4,5,6,7-Tetrahydrobenzo-
[b]thiophene with Ethyl Acetoacetate: Synthesis of Pyridines,
Pyrazoles and Their Fused Derivatives.
R. M. Mohareb and M. H. Mohamed; Heteroat. Chem. 12(6),
Page 23
518 (2001).
74- One Pot Synthesis OF Thiazolo-2-Hyhrazone, Pydino[2,3-d]-
Pyridazine, Pyrazolo[3,4-d]Pyridazine And Isoxazolo[4,5-
d]Pydrazine Derivatives.
R. M. Mohareb and D. H. Fleita; J. Heteroatom Chem., 13
(3), 258 (2002).
75- Reaction of 3-Cyano-2-amino-4,5,6,7-tetrahydrobenzo[b]-
Thiophene with Dimeric Adducts.
R. M. Mohareb, F. A. El-Omran and J. Ho; Monatash. Fur
Chemie, 133, 1443 (2002).
76- Synthesis and Biological Effects of New Derivatives of
Benzotriazole as Antimicrobial and Antifungal Agents; F. Al-
Omran, R. M. Mohareb and A. A. El-Khair; J. Heterocyclic Chem.,
39, 877 (2002)
.
77- Enantispecific Synthesis of Carbapentostatins
J. Z. Ho, R. M. Mohareb, J. H. Ahn, T. B. Sim and H.
Rapoport; J. Organic Chemistry 68, 109 (2003).
78- An Efficient Procedure for the Preparation of 4-Substituted-5-
aminoimidazoles
M. McLaughlin, R. M. Mohareb and H. Rapoport; J. Organic
Chemistry 68, 50 (2003).
Page 24
79- Reaction of
2-Diazo-3-cyano-4,5,6,7-Tetrahydrobenzo[b]thiophene With 3-
Iminobutyronitrile: Synthesis of Pyridazines, thiophenes and
their Fused Derivatives.
K. Hilmy, R. M. Mohareb, A. M. El-Torgoman, Y. Sharawy
Phosphorous, Sulfur & Silicon 178(8), 1667 (2003).
80- Synthesis and study of pigment Aggregation response of Some
Melatonin derivatives.
R. M. Mohareb, S. H. doss, G. A. Abdel- Ghany and N. I.
Louca; Pharmazie 58, 9 (2003).
81- Utility of a 2-Aminothiophene-3-carboxamide in the Synthsis
of Thienopyridines and Thienopyrimidines
R. M. Mohareb, S. M. Sherif, H. M. Gaber, S. S. Ghabrial and S.
I. Aziz; Heteroatom Chemistry, 14(5), 459 (2003).
82- An Efficient Procedure for Preparation of (1S,3R)- and
(1S,3S)-1-Amino-3-(hydroxymethyl)cyclopentanes.
H. Rapoport, Y. Ghen, R. M. Mohareb, J. H. Ahn, T. B. Sim
and J. Z. Ho; Chem. Pharm. Bull. 51 (10) 1153-1156 (2003).
83- - Synthesis and Study of Pigment aggregation response of
some melatonin derivatives.
S. H. Doss, R. M. Mohareb, G. A. Elmegeed and N. A. Luoca;
Pharmazie 58, 9 (2003).
Page 25
84- Heterocyclic Synthesis With Ethyl a-(3-carbamoyl-4,5,6,7-
tetrahydrobenzo[b]thiophen-2-ylhydrazono)acetates: An
Expeditious Synthetic Approach to Polyfunctionally Substituted
Pyran, Pyridine and Pyridazine derivatives.
R. M. Mohareb, S. M. Sherif, H. M. Gaber, S. S. Ghabrial and S.
I. Aziz; Heteroatom Chemistry, 15(4), 300 (2004).
86- Thiophenohydrazonoacetate in Heterocyclic synthesis
R. M. Mohareb, S. M. Sherif, H. M. Gaber, S. S. Ghabrial, S. I.
Aziz; Heteroatom Chem. 15, 15 (2004).
87- Synthesis of Some Novel Heterocyclic Steroids of Potential
Biological Activities: Synthesis of Isoxazolo, Pyrazolo,
Thieno and Phthalazine Derivatives of Epi-Androsterone.
S. H. Doss, R. M. Mohareb and G. A. Elmegeed, Arch.
Pharmazie in press (2004).
88- Uses of 5,5-Dimethyl-7-oxocyclohexeno[b]thiophene
Derivatives in Heterocyclic Synthesis.
D. H. Fleita, A. H. El-Banna and R. M. Mohareb; Phosphorus,
Sulfur& Silicon, 180, 2315 (2005).
89- Acycloaddition Approach to the Curing of ployimides via a
Precursor containing a Thiophene-S,S-dioxide.
A. Maggarosy, R. M. Mohareb and J. Z. Ho; Heteroatom Chem., 17(4),
1, 2006.
90- Synthesis, Structure Elucidation, and Biological Evaluation of
Some Fused and/or Pendant Thiophene, Pyrazole, Imidazole, Thiazole,
Triazole, Triazine, and Coumarin Systems Based on Cyanoacetic 2-
[(Benzoylamino)thioxomethyl] Hydrazide
Page 26
H. Z. Shams, R. M. Mohareb, M. H. Helal and A. E. Mohamoud;
Phosphoros, Sulfur and Silicon, 182, 237 (2007).
91- Synthesis of thiophenes, azoles and azines with potential biological
activity by employing the versatile heterocyclic precursor N-
benzoycyanoacetylhydrazine
R. M. Mohareb, J. Z. Ho and F. E. Elfarouk; Journal of the Chinese
Chemical Society, 54, 1053, 2007.
92- The reaction of cyanoacetylhydrazine with ω-bromoacetophenone:
Novel Synthesis of 1,3,4-Oxadiazine, Pyridazine and Coumarin
derivatives
R. M. Mohareb, R. A. Ibrahim
and J. Z. Ho; J of the Chilean Chemical
Society, 52(1), 1076 (2007).
93- USESE OF 1-CYANOACETYL-4-PHENYL-3-THIOSEMICARBAZIDE IN
HETEROCYCLIC SYNTHESIS: SYNTHESIS OF THIAZOLE, COUMARIN
AND PYRIDINE DERIVATIVES WITH ANTIMICROBIAL AND
ANTIFUNGAL ACTIVITIES
R. M. Mohareb, J. Z. Ho and A. A Mohamed; Phosphorus, Sulfur and
silicon, 182, 1661, 2007.
94- Uses of progesterone in steroidal heterocyclic derivatives of
potential antimicrobial activity.
R. M. Mohareb, H. Y. Hana; Acta Pharmaceutica, 58, 29-42 (2008).
96- The reaction of β-amino-α,γ-dicyanocrotononitrile with acetophenone:
synthesis of pyridine, pyridazine and thiophene derivatives with
antimicrobial activities.
R. M. Mohareb, K. A. El-Sharkaway and S. M. Sherif, Acta
Pharmaceutica, 58, 429-444 (2008).
97- Synthesis of New disperse azo dyes based on oxopyridine core.
Page 27
R. M. Mohareb, H. Z. Shams, M. H. Helal and I. M. Samir, Pigment and
Resin Technology, 17, 299-307 (2008).
98- The Reaction of Cyclohexan-1,3-dione with Cyanomethylenes:
Synthesis of Thiophenes and Their Fused Derivatives with Antifungal
Activities
R. M.Mohareb, S. M. Sherif and H. E. Moustafa, Phosphorous, Sulfur &
Silicon, 184, 2078-2096 (2009).
99- The Reaction of Cyanoacetic Acid Hydrazide with 2-Acetylfuran:
Synthesis of Coumarin, Pyridine, Thiophene and Thiazole Derivatives
with Potential Antimicrobial Activities.
R. M. Mohareb, E. E. Elarab, K. A. El-Sharkawy, Scientia Pharmaceutica,
77, 355-366 (2009).
100- SYNTHESIS OF NOVEL TRYPTOPHAN DERIVATIVES OF
POTENTIAL BIOLOGICAL ACTIVITY
R. M. Mohareb, N. A. Louca, G. A. Elmegeed, H. Y. Hanna, J. of Chilean
Chemical Society, 54, 175-179 (2009).
101- The Reaction of Cyanoacetylhydrazine with ω-Bromo(4-
methyl)acetophenone: Synthesis of Heterocyclic Derivatives
with Antitumor Activity.
R. M. Mohareb, A. M. Abdelazeem, Molecules, 15, 3602-3617 (2010).
102- Synthesis of hydrazide-hydrazone derivatives and their evaluation of
antidepressant, sedative and analgesic agents
R. M. Mohareb, K. A. El-Sharkawy, M. M. Hussein and H. M. El-
Sehrawi, J. of Pharmaceutical Science and Research 2(4), 185-196 (2010).
103- Synthesis of Novel Hybrid Steroids with Potential Biological
Activities: Synthesis of C-17-thiazole, isoxazole, pyrazole, thiophene and
phthalazine derivatives of epi-Androsterone.
Rafat M. Mohareb, Senot H. Doss, Gamal A. Elmegeed, Emad F.
Eskander, CURRENT TOPICS IN STEROID RESEARCH, 2010 (in press).
104- Hydrazide-Hydrazones in the Synthesis of 1,3,4-Oxadiazine, 1,2,4-
Triazine and Pyrazole Derivatives with Antitumor Activities
Page 28
Rafat M. Mohareb, Rehab A. Ibrahim and H.E. Moustafa, The open
Organic Chemistry Journal, 4, 2010 (in press).