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Dec 16, 2015

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Page 1: © Datamonitor the home of Business Intelligence intuitive deliveryexpert analysisquality data © Datamonitor.

© Datamonitor

the home of Business Intelligence

intuitive deliveryexpert analysisquality data

© Datamonitor

Page 2: © Datamonitor the home of Business Intelligence intuitive deliveryexpert analysisquality data © Datamonitor.

PharmaVitae: Daiichi Sankyo Pharmaceutical Co., Ltd HC00068-029

Slidepack

01/12

quality data expert analysis intuitive deliverythe home of Business Intelligence

Page 3: © Datamonitor the home of Business Intelligence intuitive deliveryexpert analysisquality data © Datamonitor.

Daiichi Sankyo prescription pharmaceutical performance, sales ($m) and growth rate (%), 2004–16

-7500

7501,5002,2503,0003,7504,5005,2506,0006,7507,5008,2509,0009,750

10,50011,25012,00012,75013,50014,25015,000

04 05 06 07 08 09 10 11 12 13 14 15 16

Sa

les

($m

)

-5%0%5%10%15%20%25%30%35%40%45%50%55%60%65%70%75%80%85%90%95%100%

Ye

ar-o

n-y

ear

gro

wth

rat

e (

%)

Growth rate Sales ($m)

Page 4: © Datamonitor the home of Business Intelligence intuitive deliveryexpert analysisquality data © Datamonitor.

Daiichi Sankyo financial performance ($m), 2004–16

-20,000

-15,000

-10,000

-5,000

0

5,000

10,000

15,000

20,000

25,000

04 05 06 07 08 09 10 11 12 13 14 15 16

Rx pharma Other revenues COGS

S,G&A R&D Other operating expense

Operating profit

Page 5: © Datamonitor the home of Business Intelligence intuitive deliveryexpert analysisquality data © Datamonitor.

-6,000

-4,000

-2,000

+0

+2,000

+4,000

+6,000

DA

I

AS

T

SH

I

MIT

S

DN

S

TA

K

OT

S

EIS

Ave

rag

e

Pre

scri

pti

on

ph

arm

a s

ale

s ($

m)

Core Launch Expiry Net

Daiichi Sankyo launch, core and expiry configuration vs peer set, sales ($m), 2010–16

Page 6: © Datamonitor the home of Business Intelligence intuitive deliveryexpert analysisquality data © Datamonitor.

• Lucrative cardiovascular portfolio spearheaded by the blockbuster olmesartan antihypertensive franchise.

• High levels of industrial collaboration highlighted by in-licensing with companies spanning Big Pharma and beyond.

• Impressive year for new drug approvals/launches in 2011, most notably gaining green lights for Memary, Zelboraf, Nexium and Lixiana, all of which have now launched.

• Operating profits have shown signs of recovery after declines in 2008 and 2009.

Strengths

• Over exposure to the cardiovascular market, deriving half of its total prescription pharma revenues from CV drugs, leaving Daiichi open to threats from a number of angles.

• Domestic growth could be hampered by growing use of generics and reforms impacting price.

• Daiichi forced to write down an almost $4bn loss after Ranbaxy manufacturing processes came under scrutiny from FDA, more than two thirds of the original purchase price paid by Daiichi for a controlling stake in Ranbaxy.

• Limited capital available for further deals after acquisitions of Ranbaxy and Plexxikon.

Weaknesses

• Two new launches for thrombosis market, Effient and Lixiana, could help drive Daiichi’s market share in this lucrative CV segment and broaden its focus away from hypertension.

• Expansion opportunity in the US market through established products and recent/forthcoming launches.

• Emerging market growth strategy strengthened by acquisition of Ranbaxy, particularly in India.

• Generic version of Lipitor could propel Ranbaxy generics business in US, though competing authorized generics may limit the commercial potential of this venture.

Opportunities

• 2016 patent expiry of olmesartan will have significant impact on Daiichi but not within the time constraints of this analysis. Indirect generic competition from elsewhere in the ARB class could hamper olmesartan sales.

• Weaker than hoped uptake of newly launched pipeline drugs, one example being Effient (prasugrel), which remains a key growth driver for Daiichi despite initially showing weak sales growth.

Threats

SWOT analysis of Daiichi Sankyo

Page 7: © Datamonitor the home of Business Intelligence intuitive deliveryexpert analysisquality data © Datamonitor.

Daiichi Sankyo’s key product sales ($m), 2004–16

0

2,000

4,000

6,000

8,000

10,000

12,000

14,000

16,000

04 05 06 07 08 09 10 11 12 13 14 15 16

Sa

les

($m

)

Rest of portfolio Ranbaxy Benicar/Benicar HCT Effient

Loxonin Zelboraf Memary Artist

Mevalotin ARQ 197 Azor Lixiana

Cravit Venofer Welchol

Page 8: © Datamonitor the home of Business Intelligence intuitive deliveryexpert analysisquality data © Datamonitor.

Daiichi Sankyo’s key product growth drivers and resistors ($m), 2004–10

0

2,000

4,000

6,000

8,000

10,000

12,000

200

4

Be

nica

r/B

enic

ar

HC

T

Ra

nba

xy

Cra

vit

Loxo

nin

Art

ist

We

lcho

l

Azo

r

Me

valo

tin

Re

st o

f po

rtfo

lio

201

0

Sa

les

($m

)

Start / end year Positive growth Negative growth

Page 9: © Datamonitor the home of Business Intelligence intuitive deliveryexpert analysisquality data © Datamonitor.

Daiichi Sankyo’s key product growth drivers and resistors ($m), 2010–16

0

2,000

4,000

6,000

8,000

10,000

12,000

14,000

16,000

201

0

Ra

nba

xy

Eff

ient

Zel

bor

af

Me

mar

y

AR

Q 1

97

Lixi

ana

Gra

cevi

t

We

lcho

l

Cra

vit

Re

st o

fpo

rtfo

lio

201

6

Sa

les

($m

)

Start / end year Positive growth Negative growth

Page 10: © Datamonitor the home of Business Intelligence intuitive deliveryexpert analysisquality data © Datamonitor.

Daiichi Sankyo prescription pharmaceutical sales by therapy area ($m), 2004–16

0

2,000

4,000

6,000

8,000

10,000

12,000

14,000

16,000

04 05 06 07 08 09 10 11 12 13 14 15 16

Sa

les

($m

)

CV Other Onco ID I&I CNS Uro Hema Resp GE Musco Endo

Page 11: © Datamonitor the home of Business Intelligence intuitive deliveryexpert analysisquality data © Datamonitor.

Daiichi Sankyo prescription pharmaceutical sales by geographic region ($m), 2004–16

0

2,000

4,000

6,000

8,000

10,000

12,000

14,000

16,000

04 05 06 07 08 09 10 11 12 13 14 15 16

Sa

les

($m

)

Japan US RoW 5EU

Page 12: © Datamonitor the home of Business Intelligence intuitive deliveryexpert analysisquality data © Datamonitor.

Daiichi Sankyo launch, core and expiry configuration, sales ($m), 2010–16

10,509

14,067+1,039+1,048

+2,399

-930

0

2,000

4,000

6,000

8,000

10,000

12,000

14,000

16,000

201

0

Lau

nch

Co

re

Exp

iry

Gen

eric

201

6

Sa

les

($m

)

Start / end year Positive growth Negative growth

Page 13: © Datamonitor the home of Business Intelligence intuitive deliveryexpert analysisquality data © Datamonitor.

Daiichi Sankyo prescription pharmaceutical sales by molecule type ($m), 2004–16

0

2,000

4,000

6,000

8,000

10,000

12,000

14,000

16,000

04 05 06 07 08 09 10 11 12 13 14 15 16

Sa

les

($m

)

Small molecule Monoclonal antibody Vaccine Therapeutic protein

Page 14: © Datamonitor the home of Business Intelligence intuitive deliveryexpert analysisquality data © Datamonitor.

Daiichi Sankyo prescription pharmaceutical sales by source of product ($m), 2004–16

0

2,000

4,000

6,000

8,000

10,000

12,000

14,000

16,000

04 05 06 07 08 09 10 11 12 13 14 15 16

Sa

les

($m

)

M&A Internal Co-developed In-licensed

Page 15: © Datamonitor the home of Business Intelligence intuitive deliveryexpert analysisquality data © Datamonitor.

Daiichi Sankyo operating revenue/cost analysis ($m), 2004–16

-15,000

-10,000

-5,000

0

5,000

10,000

15,000

20,000

04 05 06 07 08 09 10 11 12 13 14 15 16

Rx pharma Other revenues COGS

S,G&A R&D Other operating expense

Operating profit

Page 16: © Datamonitor the home of Business Intelligence intuitive deliveryexpert analysisquality data © Datamonitor.

Benicar/Benicar HCT sales by geography and analyst consensus ($m), 2004–16

0

500

1,000

1,500

2,000

2,500

3,000

3,500

4,000

04 05 06 07 08 09 10 11 12 13 14 15 16

Sal

es (

$m)

US 5EU JAPAN ROW Analyst consensus Global

Page 17: © Datamonitor the home of Business Intelligence intuitive deliveryexpert analysisquality data © Datamonitor.

Effient sales by geography and analyst consensus ($m), 2004–16

0

100

200

300

400

500

600

700

800

900

04 05 06 07 08 09 10 11 12 13 14 15 16

Sal

es (

$m)

US 5EU JAPAN ROW Analyst consensus Global

Page 18: © Datamonitor the home of Business Intelligence intuitive deliveryexpert analysisquality data © Datamonitor.

Zelboraf sales by geography and analyst consensus ($m), 2004–16

0

100

200

300

400

500

600

700

04 05 06 07 08 09 10 11 12 13 14 15 16

Sal

es (

$m)

US 5EU JAPAN ROW Analyst consensus Global

Page 19: © Datamonitor the home of Business Intelligence intuitive deliveryexpert analysisquality data © Datamonitor.

Memary sales by geography and analyst consensus ($m), 2004–16

0

50

100

150

200

250

300

350

400

450

04 05 06 07 08 09 10 11 12 13 14 15 16

Sal

es (

$m)

US 5EU JAPAN ROW Analyst consensus Global

Page 20: © Datamonitor the home of Business Intelligence intuitive deliveryexpert analysisquality data © Datamonitor.

© Datamonitor

the home of Business Intelligence

intuitive deliveryexpert analysisquality data

© Datamonitor