Transcript
TYPES OF CONTAINERS IN HOT LAB AND ADMINISTRATION OF RADIOPHARMACEUTICALS
What’s the hot laboratory
Hot laboratory designed for use with radioactive substances
.
BY ANOTHER WORD
A laboratory designed for research with radioactive materials that have Such high strengths that special handling precautions are required
types of Containers for
pharmaceuticals and
their uses
AMPOULE CONTAINERA container sealed by fusion and to be opened exclusively by breaking .
The contents are intended for use on one occasion only
BLISTER CONTAINER
A multi-dose container consisting of two layers, of which one is shaped to contain the individual doses. Strips are excluded .
BOTTLE CONTAINERalso known as media bottles or graduated bottles,A container with a more or less pronounced neck and usually a flat bottom .
madeof glass, plastic, borosilicate or related substances
A dark glass bottle with ground glass plug.
CARTRIDGE CONTAINERA container, usually cylindrical, suitable for liquid or solid pharmaceutical dosage forms ;
generally for use in a specially designed apparatus (e.g. a prefilled syringe) and designed to hold seed cartridges .
SINGLE-DOSE CONTAINER
single-dose container A container for single doses of solid, semi-solid or liquid preparations
GAS CYLINDER CONTAINERA container, usually cylindrical, suitable for compressed, liquefied or dissolved gas, fitted with a device to regulate the spontaneous outflow of gas at atmospheric pressure and room temperature.
VAIL CONTAINERvial A small container for parenteral medicinal products, with a stopper and overseal; the contents are removed after piercing the stopper. Both single-dose and multi-dose types exist. 1. Aspects of packagin
TUBE CONTAINER
tube A container for multi-dose semi-solid pharmaceutical forms consisting of collapsible material; the contents are released via a nozzle by squeezing the package
RADIOPHARMACEUTICALSIs radioactive substances or radioactive drugs for diagnostic and therapeutic interventions
Composition of: 1) Radioactive isotopes .2) Carrier molecule which delivers
the isotope to the area to be treated or examined.
RADIOPHARMACEUTICAL ADMINISTRATION POLICY
Confirm the patient identity and confirm that the patient is not pregnant or breast-feeding as per the policy.
Provide informed consent and have patient sign form for stress test procedures.
Verify the identity, dose and route of administration of the radiopharmaceutical with the prescribed dose from the protocol or standing orders in the procedure manual
RADIOPHARMACEUTICAL ADMINISTRATION POLICY
All doses will be verified in the dose calibrator to be within 20% of the prescribed dose. The technologist will verify by the label on the dose, the identity, dose and route of administration of the radiopharmaceutical and expiration time/date. No dose will be used past its expiration time.
All administrations will be performed in designated areas.
All injections are performed using radiation safety precautions and aseptic technique.
The exact dose amount assayed in the dose calibrator will be recorded along with the patient name, identity of radiopharmaceutical, route of administration, time and date injection, site of administration and initials of the person administering. This information will be kept in the binder labeled drug log.
Route of administration the radiopharmaceuticals
ROUTE OF ADMINISTRATION THE RADIOPHARMACEUTICALS
The most common route of administration for radiopharmaceuticals in nuclear medicine:
Intravenous injection: the radiopharmaceutical is injected into a vain. For EX 99-Tc MDP to perform a bone scan
Subcutaneous injection: the radiopharmaceutical is injected under the skin. This method is used when investigating lymphatic system.
ROUTE OF ADMINISTRATION THE RADIOPHARMACEUTICALS
Intrathecal: the radiopharmaceutical injected into fluid space . For Ex In-111 DTPA for cisternogram study.
Intracavity: the
radiopharmaceutical
injected into a cavity. For Ex treatment of malignant peritoneal or
pleural effusion
Inhalation:Theradiopharmacetial inhaled by the patient. For Ex Xe-133 gas to investigate the function of the lungs.
INTRVENOUS ADMINISTRATIONGeneral consideration:1. The syringe
containing the radiopharmaceutical should be in a syringe shield for radiation protection.
2. The operator should wear gloves and Labe coat to minimize the contamination.
INTRAVENOUS ADMINISTRATION1. Select all equipment
( tourniquet ,alcohol , syringes , needle ,saline)
2. Always explain the procedure before a begin and make the patient feel comfortable.
3. Choice the area for venipuncture , the most often inject inner the median cephalic vein
INTRAVENOUS ADMINISTRATION1. Place tourniquet on the
patient's upper arm a few inch above the elbow.
4. Use an alcohol pad to swab the area and allow the antiseptic to dry.
5. Insert the needle bevel side up so that the needle inters the lumen vein.
INTRAVENOUS ADMINISTRATION7) Apply tape to secure the
needle.
8) Release the tourniquet and inject the radiopharmaceutical.
9) Apply gentle pressure immediately with a bandage held over the puncture sit e to avoid a hematoma and control bleeding.
References: Notes on Nuclear Medicine Imaging http://www.slideshare.net/NagaRaju52/radiopharmaceutic
als-32503130 Radiopharmaceutical – Wikipedia Radiopharmaceutical Administration Policy http://apps.who.int/medicinedocs/documents/s19638en/
s19638en.pdf https://books.google.com.sa/books?
id=wv47n8SvwsoC&pg=PA181&lpg=PA181&dq=blister+container+of+radiopharmaceuticals&source=bl&ots=qFfzw7hbu8&sig=A59iMUZ2eRI4AFynBb96Saq6yE4&hl=ar&sa=X&ved=0ahUKEwiYsLmL-LjJAhXJwBQKHSqcBO4Q6AEIHDAA#v=onepage&q=blister%20container%20of%20radiopharmaceuticals&f=falsehttps://en.wikipedia.org/wiki/Reagent_bottle
MADE BY; MARAM AHMED ALMOWALLADNOURA ALZAHRANY
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