Medical Facts of STEM CELL THERAPY in Rheumatoid Arthritis

Medical Facts of STEM CELL THERAPY

Dr. Sharda JainMr. Prabhu Mishra DR. YOGESH AGARWALA Dr. Rajesh Dhall Dr. Rashmi JainDr. Indu TyagiMs. Himani Agnihotri

in Rheumatoid Arthritis

Public Awareness series

WELCOME to world of STEM CELL THERAPY – a Medical Revolution in Rheumatoid

Arthritis to manage Day Today Life & Halt the Disease Process

RHEUMATOID ARTHRITIS

Rheumatoid arthritis or RA is an autoimmune condition, which primarily affects the synovium in

the knee, causing inflammation followed by destruction of the joint surfaces.

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Advance Disease Pictures

SYMPTOMS

• Initial symptoms of RA are generally pain and morning stiffness.

• RA in the knee can be isolated or be a part of generalized pain.

• The disease, which starts as synovitis in the knee, progresses

to destroy the joint.

SYMPTOMS

• Classically, there would be involvement of small joints of the

hands and feet.

SYMPTOMS contd…..

• The disease is characterized by episodes of acute inflammation interspersed with periods of remission.

• When the arthritis takes toll on the cartilage of the knee, the joint becomes deformed and painful even to the slightest of movement.

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LAB TEST

• Blood tests can be useful to make a diagnosis of RA. Blood tests will show the presence of the antibody called rheumatoid factor (RA test). HOWEVER, ABSENCE OF THE ANTIBODY DOES NOT EXCLUDE RA.

• X-RAYS IN EARLY RA CAN BE NORMAL, as the involvement would limit to the synovium.

• Over a long period of time, X-rays will reveal destruction of joint margins, deformity, bone loss and severe osteoporosis.

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Please remember

• It is Bad and Progressive disease, that leaves you

incapable to do anything if you don’t take timely

action.

MANAGEMENT AND TREATMENT

• It is now universally acceptable that there is

NO complete cure for RA.

TREATMENT IS MAINLY SUPPORTIVE

- Treatment methods are aimed to reduce pain and inflammation.

- Attempts are also made to slow down joint damage and try and

improve general well- being.Here comes the role of

Stem Cell therapy.www.globalstemgenn.com

MANAGEMENT OF RHEUMATOID ARTHRITIS CONTD…

• RA management is a Team Effort, headed by a rheumatologist together with other health professionals such as physiotherapists, occupational therapists, nurses, psychologists, orthopaedic surgeons and social workers.

• The treatment modalities include counselling, medication, physiotherapy and ultimately Stem Cell therapy or Surgery.

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MEDICATIONS FOR RA

• NSAIDs are lifeline.• CORTICOSTEROIDS – the role

of corticosteroids in RA is highly controversial.

DISEASE - MODIFYING DRUGS IN Rheumatoid Arthritis

• Injectables gold salts, certain cancer drugs like Methotrexate, anti-malarial agents like Hydroxychloroquin and anti-inflammatory drugs of bowels like Sulfasalazine are some of the popular disease – modifying drugs used in Rheumatoid Arthritis.

• These drugs need proper & intensive monitoring and least to decrease side effects.

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• STEM CELL THERAPY IS QUITE HELPFUL IN PATIENTS NOT RESPONDING TO CONVENTIONAL TREATMENT.

• Stem cell therapy - does improve the quality of life and helps getting rid of most of the manifestations of Rheumatoid Arthritis.

World Research withStem Cell Treatment in Rheumatoid

Arthritis

Conclusion WORLD RESEARCH ON Rheumatoid Arthritis

WITH STEM CELL THERAPY

• MSC therapy may be valid alternative for rheumatoid arthritis with chronic knee arthritis.

• The intervention is simple, does not require hospitalization or surgery, provides pain relief, and significantly improves cartilage qualty & quality of life.

Stem cell therapy improves the quality of life.

However the response Varies from patient

to patient

WORLD RESEARCH ON Rheumatoid ArthritisWITH STEM CELL THERAPY

We are happy with Stem Cell therapy in improving the quality of life and mobility in

Rheumatoid Arthhritis

Global stemgenn makes suitable stem cell therapy available to the ailing

patient only after thorough scientific deliberations and meticulous

counseling of patient & family with experts.

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Our USP• World class clinicians and experts from Regenerative medicine.• State of the art, in-house stem cell lab to maximize the

yield of good quality Stem Cells• Accurate treatment protocols for “relevant disorders”• Proven results and experience in handling complex case • We use Autologous stem cells for Stem Cell Therapy

(Bone Marrow, Fat, Blood)

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• Autologous cells for homologous use• Same setting surgery• Minimal manipulation of cells• Don’t promote therapeutic results

You should knowFDA – guidelines…

• This is a patient-funded clinical trial

• Stem Cell Therapy is NOT COVERED BY INSURANCE• Public undertakings DO ALLOW in GUJARAT• The cost of the therapy ranges & mainly depends on the

complexity of the case

Fees and Insurance cover

Global stemgenn offer you stem cell therapy using latest technology. These stem cells could be of various types viz. Hematopoietic (CD 34+), Mesenchymal stem cells

(MSCs) that are processed and isolated using Good Manufacturing Practice (GMP) and Good Lab Practice (GLP) in accordance with AABB standards.

Our Lab USP

Our overall experience of Stem cell therapy at Global Stemgenn

- It is completely safe, Non –Toxic and totally devoid of side effects

with good probability of homing and engraftment with the parent cell, tissue or

organ.

Patient – SafetyEndorsed by Doctor Pateints

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DOCTORS

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