MedActive Oral Care for Dry Mouth Conditions
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™
© 2012 MedActive, LLC.
Four Brands MedActive - Oral Care Redefined™
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MedActive redefines oral care by prioritizing dry mouth relief as a
critical objective of daily oral hygiene.
MedActive’s integration of continuous dry mouth relief into
comprehensive oral care is based upon clinical recognition that
salivary dysfunction adversely impacts oral and general health,
especially for patients managing chronic illness.
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Causes of dry mouth and other oral conditions:
• Cancer Chemotherapy & Radiation Therapy • Kidney Dialysis • Transplant Surgeries
• Antibiotics • Diuretics • Muscle relaxers • Corticosteroids • Amphetamines
• Anticholinergics • Analgesics • Antipsychotics • Antihistamines • Antidepressants
Health Condtions
Medications
Medical Treatments
• Diabetes • COPD • Heart Disease • Cancer • High Blood Pressure • Rheumatoid Arthritis • Depression
• Anxiety • Lupus/Scleroderma • Pneumonia • Asthma • Allergies • Sjögren’s Syndrome • HIV/AIDS
• Hepatitis • Sleep Disorder • GERD • Obesity • Incontinence
• Antihypertensives • Decongestants • Sedatives • NSAIDS
Lifestyle
• Poor hygiene • Smoking • Drug & alcohol abuse • Infrequent dental visits
MedActive® Brands rely on multiple applications of proprietary ingredients throughout the day. These applications achieve unprecedented relief from dry mouth discomfort.
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Repetitively enhancing saliva flow, with Spilanthes Extract and its unique “tingle”
feature
Repetitively moisturizing soft tissue, with ULTRAMULSION® and its extraordinary
“mouthfeel” and flavor enhancement
Repetitively lubricating and conditioning the mouth, with a mucoprotectant and
its distinct substantivity to soft tissue.
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Caries
Cascade Effects of
Dry Mouth
Immune System
Compromise
Bacterial Overgrowth
Viral & Fungal Overgrowth
Pathogenic Biofilm
Gingivitis
Periodontitis
Stomatititis
Mucositis
Inflammation
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Health Impacts of Dry Mouth
Dysphagia Immuno-
compromise
Kidney disease
Migration of biofilm into
bloodstream
Ingestion of bacteria, virus
& fungi
Depression
Pulmonary Infections
Stroke
Diminished quality of
life
Heart disease
Malnutrition
Bacteremia
Cancer
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Patient Populations
Sjögren’s Syndrome
Denture Discomfort
Hyper-tension
Allergies
Kidney Dialysis
Alzheimer's & Dementia
COPD
Diabetes Palliative
Care
Gastro-intestinal problems
Drug Dependency
Sleep Apnea
Obesity
Depression & Anxiety
Parkinson’s
Arthritis
MS, Scleroderma
& Lupus
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Integration of Dry Mouth Management into Patient Centered Care Pathways Reduces Costs
Downstream Medical Costs
Increased dental care
Nosocomial infections
Regulatory risk
Litigative risk
Reduced HVBP
Incentives
Increased drug costs
Empty bed losses
Longer & more frequent
hospitalizations
Increased care costs
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Dry mouth leads to and exacerbates the following conditions:
• Oral thrush • Sensitivity • Sores & lesions • Hoarsness • Caries
• Gingivitis/Periodontitis • Bleeding gums • Inflammation • Burning mouth • Throat irritation • Difficulty swallowing
Percentage of Adults who have had problems involving the mouth
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“QuickStats: Percentage of Adults* Aged 18-64 Years Who Have Had Problems Involving the Mouth, by Race/Ethnicity and Type of Problem ---National Health Interview Survey, United States, 2008.” Centers for Disease Control and Prevention. Morbidity and Mortality Weekly Report (MMWR). http://www.cdc.gov/mmwr/preview/mmwrhtml/mm6022a7.htm?s_cid=mm6022a7_w
MedActive provides comprehensive oral care which includes continuous oral relief for patient-centered integrated care pathways.
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Taking the appropriate efforts to improve oral and dental care for nursing home
residents could have a significant impact not only on quality of life for nursing
facility residents, but also a meaningful impact on downstream medical costs for
the health care system by preventing hospitalizations and death resulting from
medical care needs arising out of poor oral and dental care.
“
”
Dentition problems can result in malnutrition
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Patients with painful dentition eat less, and if the patient is demented at baseline, the communication of the painful condition is often missed by care providers.
Dentition problems along with the normal loss of the sense of smell accompanied with aging can result in signficantly reduced caloric intakes. Malnutrition frequently
leads to immunocompromise and this puts individuals at risk for a whole host of opportunistic infections such as urinary tract infections and pneumonia, both of
which are common primary diagnoses for nursing home patients admitted to acute care centers.
“
”
MedActive protocol encourages and promotes ongoing self-care and independence.
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Senior citizens fear moving into a nursing home and losing their
independence more than death, according to a research study that
examines the attitudes and anxieties of the nation’s elderly population.
“Aging in Place in America,” commissioned by Clarity
and The EAR Foundation ”
Four Brands Facts
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Approximately 300,000 cases of ventilator-associated pneumonia (VAP) are reported annually, associated
with increased morbidity and mortality, and costs up to $50,000 per case.1 In a 2008 study in an acute care facility with 4 critical care units, the implementation of a q4
oral care protocol costing $21.35/day resulted in an annual savings of more than $7,722.1
The January 2012 issue of the JADA reported that patients with diabetes were one third less likely to visit an
emergency department or be hospitalized for the disease when regular dental care was received.2
1 Killer, Harriet S., RN, BSA, CIC, CPA & Tara Haines, RN, BSN. Simple & Cost-Effective Strategies to Reduce the Occurrence of Ventilator-Associated Pneumonia. Ocala Regional Medical Center, Ocala, FL. 2008. 2 The Journal of the American Dental Association. January 1, 2012. Vol 143, No. 1, 20-30. 3 Bad teeth cause malnutrition in elderly. BBC News Health. May 21, 1999. 4The National Kidney Foundation. http://www.kidney.org/.
Undiagnosed dental and oral problems could be a leading cause of malnutrition in elderly people – the
problem may be exacerbated by a failure of residential and nursing homes to ensure residents receive
proper basic oral care. 3
Patients on dialysis often feel thirsty, but are instructed to control their fluid intake. These patients are
constantly looking for a way to relieve their dry mouth and satisfy their thirst.4
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Physical Removal of Pathogenic Biofilm
Inhibition of Bacterial Migration
Remineralization of Tooth Surfaces
Saliva Enhancement
Soft Tissue Conditioning
Ongoing Immune System Support
Comprehensive
Continuous
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The CONTINUUM
™ Continuous, Comprehensive Oral Care & Relief
The Interactive Relationship of Saliva & Mucosal Soft Tissue Supports a Healthy Mouth
MedActive’s Proprietary Formulation: Spilanthes Extract & ULTRAMULSION® Enhances saliva and coats/soothes the soft tissues of the mouth
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Nighttime Care Daytime Relief
Rinse PROPHY TAPE® (Floss)
Gel Spray Lozenges
Four Brands
2
Summary of the
Physical removal of plaque biofilms
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Continuous conditioning of soft tissue
Continuous remineralization of teeth
Continuous enhancement of saliva flow
Continuous cleansing of oral biofilm
Continuous relief of oral discomfort
Oral Professionals and Pharmacists Recognize Medication-Induced Dry Mouth Risk
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WhiteHill Oral Technologies Stafford, TX
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• All MedActive Brands are proprietary patented technology • ULTRAMULSION® and Spilanthes Extract are exclusively licensed by WhiteHill to MedActive for healthcare • WhiteHill provides MedActive with:
o Manufacturing (GMP) o Quality Control o Quality Assurance o Research & Development o FDA Label Claims Guidance
Licensed Intellectual Property
PAGE 22 OF 23
Pending U.S. Patent Applications:
10/331,800 11/149,597 11/331,513 11/349,042 11/549,668 11/671,075
Issued U.S. Patents:
5,711,936 6,609,527 5,057,310 6,575,176 6,138,314 6,907,889 6,086,373 6,916,880 6,545,077 7,017,591
Pending U.S. Trademark Applications:
HI-IMPACT™
feel it working™
feel ‘m working™
Patient-Friendly™
Oral Relief CONTINNUM™
PROPHYLAXIS ESSENTIALS™
Clean, Lubricate, Moisten & Protect™
Biofilm Targeting™
Biofilm Management™
Registered U.S. Trademark:
MedActive®
ULTRAMULSION®
PROPHY TAPE®
SOFT ABRASIVES®
MedActive Oral Pharmaceuticals, LLC.
Headquarters:
8364 Forest Oaks Blvd. Spring Hill, FL 34606 U.S.A.
Phone: 352-293-2164 Fax: 352-835-7180
© 2011 MedActive, LLC.
Contact
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