M2/25EXAM 1Chapters 1, 3, 4, and pp185-201 W2/27Ch. 2More molecular development of Drosophila M3/3CLASS MEETS IN THE LIBRARY, Room 518 of the Glickman.

M 2/25 EXAM 1 Chapters 1, 3, 4, and pp185-201W 2/27 Ch. 2 More molecular development of DrosophilaM 3/3 CLASS MEETS IN THE LIBRARY, Room 518 of the Glickman Library. Please bring a copy of the primary research article you have selected (or more than one if you haven’t decided) plus your notes on the article.

W 3/5 Ch. 6 Plant developmentM 3/10 More plant development W 3/12 Ch. 7 Mechanisms of morphogenesis

M 3/17 More mechanisms of morphogenesisW 3/19 Ch. 8 Cell differentiationM 3/24 no class - Spring Break W 3/26 no class - Spring BreakM 3/31 Ch. 9 OrganogenesisW 4/2 EXAM 2 Chapters 2, 6, 7, 8, and some of 14

Development is one of the top journals in the field of developmental biology. Abstracts for the articles that appear in Development are online at http://dev.biologists.org/ . You should choose an article that is in the “Research Articles” section (this is a primary research article rather than a review). You should be able to download articles for free that are more than six months old. Scan through abstracts in the journal and select one that covers a topic you find interesting - but you don’t need to understand any of the details of the article at this point. Once you are set on your research article, the next step will be to identify one or two review articles (These are often cited in the Introduction of the paper) and read them. Bring the article to class in Room 518 of the Glickman Library on March 3 rd and we will discuss what your article is about and learn about how to use science databases. Be prepared to describe the article - but you don’t need to understand the details at this point.

Bring the article to class in Room 518 of the Glickman Library on March 3rd

NEXT Monday WE MEET IN THE LIBRARY.

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Genes to focus on during Drosophila embryogenesis

BicoidHunchbackEven-skippedEngrailedAntennapedia

HedgehogWingless

Gurken

TollDorsalDecapentaplegicShort gastrulation

p.85 Summary

all genes

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The Hox gene family are examples of homeotic genes.

Homeotic genes are genes that when mutant cause a change in the

spatial position of structures (change in address).

Box 4A

wild-type fruit flyantennapedia mutant

The Hox gene family are examples of homeotic genes.

Homeotic genes are genes that when mutant cause a change in the

spatial position of structures (change in address).

Box 4A

The Hox gene family are examples of homeotic genes.

The Hox gene products give the positional addressalong the Anterior-Posterior (A/P) axis in all animals.

Box 4A

2.8 fly A/P axisgene hierarchy

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