Keto cloud® part 2 the history of epilepsy treatment

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The history of epilepsy treatmentFrom 1322 BCE until tomorrow.

We will follow the history of Epilepsy treatment throughoutrecorded history. And see what happened at the time of…

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Tutankhamen 1322 BCE

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Tutankhamen 1322 BCE

Hippocrates 500 BCE

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Tutankhamen 1322 BCE

Hippocrates 500 BCE

Biblical Times

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Tutankhamen 1322 BCE

Hippocrates 500 BCE

Biblical Times

Crusades 1200 AD

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Tutankhamen 1322 BCE

Hippocrates 500 BCE

Biblical Times

Crusades 1200 AD

Leonardo Da Vinci 1500 AD

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Tutankhamen 1322 BCE

Hippocrates 500 BCE

Biblical Times

Crusades 1200 AD

Leonardo Da Vinci 1500 AD

Nineteenth Century

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Tutankhamen 1322 BCE

Hippocrates 500 BCE

Biblical Times

Crusades 1200 AD

Leonardo Da Vinci 1500 AD

Nineteenth Century

Twentieth Century

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Tutankhamen 1322 BCE

Hippocrates 500 BCE

Biblical Times

Crusades 1200 AD

Leonardo Da Vinci 1500 AD

Nineteenth Century

Twentieth Century

2000 and Beyond

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Tutankhamen 1322 BCE

Hippocrates 500 BCE

Biblical Times

Crusades 1200 AD

Leonardo Da Vinci 1500 AD

Nineteenth Century

Twentieth Century

2000 and Beyond

.

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Many famous people suffered from epilepsy.

Particularly highly intelligent, creative / strategic thinkers.

These include the likes of:

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582-507 BCE Pythagoras

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582-507 BCE Pythagoras

470-399 BCE Socrates

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582-507 BCE Pythagoras

470-399 BCE Socrates

384-322 BCE Aristotle

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582-507 BCE Pythagoras

470-399 BCE Socrates

384-322 BCE Aristotle

100-44 BCE Julius Caesar

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582-507 BCE Pythagoras

470-399 BCE Socrates

384-322 BCE Aristotle

100-44 BCE Julius Caesar

1412-1431 Joan of Arc

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582-507 BCE Pythagoras

470-399 BCE Socrates

384-322 BCE Aristotle

100-44 BCE Julius Caesar

1412-1431 Joan of Arc

1768-1830 Napoleon

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582-507 BCE Pythagoras

470-399 BCE Socrates

384-322 BCE Aristotle

100-44 BCE Julius Caesar

1412-1431 Joan of Arc

1768-1830 Napoleon

1890-1976 Agatha Christie

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582-507 BCE Pythagoras

470-399 BCE Socrates

384-322 BCE Aristotle

100-44 BCE Julius Caesar

1412-1431 Joan of Arc

1768-1830 Napoleon

1890-1976 Agatha Christie

1898-1937 George Gershwin

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582-507 BCE Pythagoras

470-399 BCE Socrates

384-322 BCE Aristotle

100-44 BCE Julius Caesar

1412-1431 Joan of Arc

1768-1830 Napoleon

1890-1976 Agatha Christie

1898-1937 George Gershwin

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1332 to 1322 BCE Tutankhamen

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Tutankhamen ruled his kingdom for only10 years before he died at a very youngage.

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Tutankhamen ruled his kingdom for only10 years before he died at a very youngage.

His death remains a mystery.

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Tutankhamen ruled his kingdom for only10 years before he died at a very youngage.

His death remains a mystery.

Nevertheless…..

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“”

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“”

—Jessica Hamzelou, New Scientist September 11 2012

—Washington Post

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A remarkable realisation was recently made:

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A secret buried in Egyptian hieroglyphics.

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This is the hieroglyphic name for Epilepsy.“Nesejet”

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“Cobra”

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“Cobra”

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“Cobra”

Meaning: “From the Gods” or “Controlled by the Gods”

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“Loaf of bread”

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“Loaf of bread”

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“Loaf of bread”

Meaning: “Food”.

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“Loaf of bread”

Meaning: “Food”.

(This is the first time in history that food is mentioned in relation to Epilepsy. The significance of this will become clear later on.)

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“Man with stick”

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“Man with stick”

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“Man with stick”

Meaning: “Danger”

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“Cobra”

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“Cobra”

“Loaf of bread”

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“Cobra”

“Loaf of bread”

“Man with Stick”

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“Uncontrollable”

“Food”

“Danger”

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Around this time in history, it was accepted thatepilepsy was some kind of spiritual Manifestation.

Hippocrates of Kos, who is considered by many tobe the father of modern made the followingstatement:

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“ ”Secret disease is neither demonic nor divine.

--Hippocrates of Kos

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He discovered that there were environmentalissues at play and that fasting had and effect onthe seizure duration and seizure type.

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He discovered that there were environmentalissues at play and that fasting had and effect onthe seizure duration and seizure type.

(The significance of this will become clear later on)

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His treatment for Epilepsy was based on dietaryintervention rather than a treatment based onherbs (Drugs).

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His treatment for Epilepsy was based on dietaryintervention rather than a treatment based onherbs (Drugs).

(This was the second reference to food in relation to

Epilepsy.)

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When confronted by the disciples, Jesus wasasked why they (the disciples) cloud not castout the demons (as epilepsy was knownthose days).

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“”

Mark 9:29

And Jesus said unto them, This kind cancome forth by nothing, but by prayer andfasting.

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Mark 9:29

And Jesus said unto them, This kind cancome forth by nothing, but by prayer andfasting.

(This is the third reference to food in relation to Epilepsy. The significance of this will become clear later on)

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John of Gaddesden (1280-1361 AD)distinguishes three forms of epilepsy:

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John of Gaddesden (1280-1361 AD)distinguishes three forms of epilepsy:

Minor

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John of Gaddesden (1280-1361 AD)distinguishes three forms of epilepsy:

Minor

Medium

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John of Gaddesden (1280-1361 AD)distinguishes three forms of epilepsy:

Minor

Medium

Major

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The phrase “Petit Mal” and “Grand Mal”seizures were coined during this time.

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During the Medieval times, it was thought thatepilepsy was a contagious disease,

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During the Medieval times, it was thought thatepilepsy was a contagious disease,

People with epilepsy were put in asylums,

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During the Medieval times, it was thought thatepilepsy was a contagious disease,

People with epilepsy were put in asylums,

Common treatment for Epilepsy was torture.

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Bleeding was common practice to expel bad blood.

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Bleeding was common practice to expel bad blood.

First asylum - St. Mary of Bethlehem Hospital in London(known as Bedlam).

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Willis hypothesises that an epileptic seizure is

“An explosion of animal spirits in the meninges”.

--Willis, 1682

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During this period of time descriptions and mentions of epileptic seizure became more frequent.

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First AED: the introduction of bromide potassium in thetreatment of epilepsy by Edward Sieveking, in 1857.

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This was an accidental discovery, bromide potassium wasused to suppress the libido of epilepsy patients.

It was accepted that epilepsy was hereditary andtherefore people with epilepsy should be stopped fromhaving babies.

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Other nineteenth century procedures to cure epilepsywere:

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Trephining (drilling a hole in the skull) was still supported by:

Charles-ÉdouardBrown-Séquard, Benjamin W. Dudley (1785–1870),

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Tracheoctomy: Making an incision on the anterior aspect of the neck and opening a direct airway through an incision in the trachea.

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In the beginning of the Twentieth century, the JohnsHopkins Hospital in Baltimore studied the effect of foodon Epilepsy and discovered the link between food andEpilepsy.

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A group of epilepsy patients was selected and deprivedof food for several days. The result was that two third ofthe patients stoped having seizures after three days.

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Why this was the case was never discovered, but howthis effect could be sustained was discovered soon after.

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The state the patient enters is called Ketosis.

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The state the patient enters is called Ketosis.

While in this state the brain doesn’t use glucose butketones for nutrition.

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The body creates these ketones when there isinsufficient glucose available.

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The diet that maintains this state of Ketosis is called the Ketogenic Diet.

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Although very effective, the Ketogenic diet has neverbeen used to its full potential because of manydifficulties physicians face:

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These difficulties are:

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These difficulties are:

Prescription

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These difficulties are:

Prescription

Administering

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These difficulties are:

Prescription

Administering

Maintenance

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These difficulties are:

Prescription

Administering

Maintenance

Supervision

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Medication became available that came close to theeffectiveness of the Ketogenic Diet.

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Late in the twentieth century the Ketogenic Dietemerged once again as a pharmaceutical free alternativeto medication with sometimes major side effects.

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Keto-Cloud LLC is a company that has taken the challengeto overcome these difficulties by employing moderncommunication technology and tapping into thecomputing power most of us carry around in ourpockets.

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The History of Epilepsy Treatment

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From 1322 BC until tomorrow

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