Introducing Intuvo 9000 GC System€¦ · Introducing Intuvo 9000 GC System • A completely re-imagined integrated system of GC consumables, MS services and software • New paradigm
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1
Introducing Intuvo 9000 GC System
• A completely re-imagined
integrated system of GC
consumables, MS
services and software
• New paradigm streamlining
the way GC is done
• Better Business Outcome
• Easier
• Faster
• Smaller
• Smarter
• Greener
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Innovating a New Path to GC Productivity
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Direct
heating
A whole new way to GC
Innovating a New Path to GC Productivity
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No-trim
column
Direct
heating
A whole new way to GC
Innovating a New Path to GC Productivity
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No-trim
column
Direct
heating
A whole new way to GC
Innovating a New Path to GC Productivity
Ferrule-free click-and-run
connections
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Disposable
Guard chip
No-trim
column
Direct
heating
A whole new way to GC
Innovating a New Path to GC Productivity
Ferrule-free click-and-run
connections
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Disposable
Guard chip
No-trim
column
Direct
heating
Modular
Intuvo flow chips A whole new way to GC
Innovating a New Path to GC Productivity
Ferrule-free click-and-run
connections
Flexible Compatible Design Configurable to any application
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• SSL, MMI, GSV, LSV inlets
• FID, TCD, ECD, NPD, FPD,
NCD, SCD detectors
• SQ and TQ mass spectrometers
• Headspace, thermal desorption,
purge and trap samplers
• 16-, 50-, 150-position
auto-injectors and trays
Seamless Method Migration to Intuvo Preserving method and SOP investments
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+ TIC Scan 12 CAL 10 (20000 ppb) - Apr 30.d
Counts (%) vs. Acquisition Time (min)
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+ TIC Scan 12 Cal-10 (Dec 10) 20000 ppb .D
Counts (%) vs. Acquisition Time (min)
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83 SVOC by US EPA 8270
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+ TIC Scan 12 Cal-10 (Dec 10) 20000 ppb .D
Counts (%) vs. Acquisition Time (min)
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+ TIC Scan 12 CAL 10 (20000 ppb) - Apr 30.d
Counts (%) vs. Acquisition Time (min)
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Seamless Method Migration to Intuvo No business disruption
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Intuvo
7890
83 SVOC by US EPA 8270
Innovating the GC Flow Path
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To detector
Conventional
flow path
Inlet
Gold seal
Nuts and ferrules
Classic capillary
column
Innovating the GC Flow Path
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To detector
Conventional
flow path
Intuvo
flow path
Inlet Inlet
Guard chip
Gold seal
Nuts and ferrules
Classic capillary
column
Innovating the GC Flow Path
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Click-and-run
direct
connections
To detector
To detector
Conventional
flow path
Intuvo
flow path
Inlet Inlet
Guard chip
Intuvo planar
column
Gold seal
Nuts and ferrules
Classic capillary
column
Flow
chip
Click-and-Run Direct Connections Eliminating connection uncertainty
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• No more ferrules
• Direct face seal connections
• Audible and tactile click lets
you know connection is made
• Easier to train
• Less unplanned downtime
• Fewer batch reruns and
precious samples lost
A New Portfolio of GC Consumables
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UI Inlet Liners Guard Chip
No-trim
column
Intuvo
Flow
Chips
Smart Keys
Tools &
Accessories
Intuvo Flow Chips
July 10, 2017
Confidentiality Label
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• Modular microfluidic
chips
• Configures flow path from
inlet to detector
• Provides ferrule-free
connections
• Volumes, restrictions and
flow rates are known
precisely eliminating the
need for complicated flow
calculators
Flow Chips
Inlet
Connections*
connect
guard chip column
Split flow from guard chip two columns
CFT Connections**
Mid-column backflush
Post column backflush
Detector Connections*
Connect column GC detector(s)
Connect column MS
Split column flow multiple detectors
Detector “Tails” * Detector-specific flow
path
*- minimum requirement
**- optional accessory
Autonomous Leak Checking Avoiding unplanned downtime
Microfluidic-enabled 6th generation EPC modules allow hands-free leak
checking to confirm and document leak-free operation autonomously.
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Fast Direct Heating and Cooling Every single minute counts
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• Fast, efficient heating
• Ballistic cooling
• Smaller footprint
“We are the police – we need answers
fast. Even 1 minute faster cool-down
would be valuable…”
Ultra Fast GC It’s All About How Well You GC Fast
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min 0 0.5 1 1.5 2 2.5
pA
0
500
1000
1500
2000
2500
3000
C5
C6
C7 C8 C9
C10
C11
C12
C14
C15
C16
C17
C18
C20 C24 C28 C32 C36 C40 C44
5 replicate overlay of ASTM D7798 SimDist standard mix
Recovery
C5 0.9
C6 0.9
C7 1.0
C8 1.0
C9 1.0
C10 1.0
C11 1.0
C12 1.0
C14 1.0
C15 1.0
C16 1.0
C17 1.0
C18 1.0
C20 1.0
C24 1.0
C28 1.0
C32 1.0
C36 1.0
C40 1.0
C44 0.9
• Excellent retention time and
area count reproducibility
• No concern for cold spots
Efficient, Even Direct Heating
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0.00
0.50
1.00
1.50
2.00
2.50
0 10 20 30 40 50 60 70 80
Rela
tive
Resp
on
se
Compound Number
7890Intuvo
Benzo[b]fluouranthene
Benzo[k]fluoranthene
Benzo[a]pyrene
Perylene-d12(ISTD)
Indeno[1,2,3-cd]pyrene
Dibenz[a,h]anthracene
Benzo[ghi]perylene
0
20
40
60
80
100
120
17 18 19 20 21 22 23
PAHs0.098ug/mL9000/5977A(scan)
High molecular
weight PAH
compounds also
have largely identical
response factors
Even high molecular
weight compounds such
as Benzo(ghi)perylene
(mol wt 276 amu) have
excellent peak shape
Optimizing Lab Space Supporting lean laboratory thinking
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Less than half:
• Power consumption
• Heat output into laboratory
• Laboratory bench footprint
• Lower operating costs
• Higher efficiency
• Greener
Modular Intuvo Flow Chips High purity inert silica flow path
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• Inert
• Modular, configurable
• Click-and-run connections
Intuvo Flow Chip
cross section
Thermally conductive
proprietary alloy
High purity
silica channel
Intuvo ultra inert
treatment
Carrier
gas
Intuvo Inert Flow Path Optimized for active compounds
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5 ppb Injection of pesticide mix
TQ MRM Transitions Chrysene-d12
EPN
Pyroclostrobin
Perylene-d12
Phosalone
Coumaphos
Agilent 7000 TQ/MS
Intuvo Guard Chip and No-trim Columns Running more, maintaining less
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• Simple disposable design
• No column trimming
• Retention time reproducibility
• Less maintenance time
• Less recalibration and
requalification
• Less unplanned downtime
Intuvo Guard Chip and No-trim Columns No retention time shifts after maintenance
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0.5 min
Shifts beyond
retention time
window
Pesticide mix injected before and
after 300 mm column trim
0.5 min
Maintaining
retention times
Pesticide mix injected before and
after guard chip change
Conventional Column Intuvo Column
Intuvo Guard Chip Protect, don’t repair
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• US EPA 8270D SVOC in soil
• Tailing factor slowly increases
during 240 soil extract
injections
• Guard chip replacement
restores analytical
performance and
extends column life
EPATailngFactorLimit
0.0
0.5
1.0
1.5
2.0
2.5
0 50 100 150 200 250 300 350 400
TailingFactor
NumberofMatrixInjections
BenzidineChange guard chip:
No clipping
Intuvo Columns Maintain Integrity
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Example
• US EPA 8270D SVOC in soil
• 30-m columns
• Conventional column clipped
0.3-m every second day:
Lasted 4 weeks
• Intuvo guard chip replaced every
second day:
Lasted 6 weeks
• No trimming, fewer column
replacements, fewer
recalibrations:
3x less maintenance
Intuvo Smart Keys Self aware
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• Flow Chips and Columns
• Smart: Informs how Intuvo is
configured
• Easy: Sets method context and
parameter defaults – no
complex calculators needed
Accessing the Power of Innovation Transforming the user experience
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New mobilized generation
• Expectations of remote mobile
connection
• Technology accessed through
interactive graphic SW and
apps
Make technology accessible
• Interface meeting today’s
expectations
Intuvo Graphical User Interface
• System status
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Intuvo Graphical User Interface
• System status
• Real-time
chromatograms
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min.0.6 0.8 1.0 1.2 1.4 1.6 1.8
pA
0
500
1000
1500
2000
2500
3000
Intuvo Graphical User Interface
• System status
• Real-time
chromatograms
• Step-by-step user
maintenance and
troubleshooting
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Intuvo Graphical User Interface
• System status
• Real-time
chromatograms
• Step-by-step user
maintenance and
troubleshooting
• Finding parts fast
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ReplaceInletLiner
FindInletParts
InletLinerPartNumber8001-
0101
Internet of Things A full suite of customer support
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• Intuvo serves up a web
homepage
• User help for
Maintenance,
troubleshooting and
diagnostics
• Accessible through any
approved PC or mobile
device securely on
internal network
Keep Connected Tablet or phone connectivity
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Go Mobile
Check instrument and batch
status remotely
Confirm laboratory operations
while out of the laboratory
Connect to any instrument with
a single mobile device
Intuvo Graphical User Interface Interactive maintenance
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Remove lock nut and septum
Replace liner
Step 1: Remove lock nut
A Gateway of Information at Your Fingertips Whenever and wherever you are
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• On-line
resources
• Agilent University
• YouTube
• Agilent.com
• Agilent GC
community
Agilent CrossLab Services for Intuvo A streamlined service experience
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Intuvo 9000 GC Health Report
Installation and familiarization
Compliance services
Education
An Ideal Partner for Mass Spectrometry
• Guard chip protection of
column and MS ion source
• Retention time stability after
changing guard chip
• Easy and reliable backflush
• Leak-free click-and-run
connections
• Fast direct heating and cooling
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Intuvo 9000 GC System Appealing to all stakeholders
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Operator and Scientist
• Simpler operation, less training, fewer mistakes
• Innovative enabling technology: Future of GC
Lab Manager
• Less unplanned downtime and disruption
• Delivering results with confidence
Business Executive
• A better financial return on innovation
• Improved operations and business continuity
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