Transcript
The endocrine system
Endocrine cells:Endocrine glandsEmbedded in other organs (pl. enteroendocine system)
Regulation: synthesis of chemical transmitter molecules (hormones)Endocrine glands:
No excretory ductRelease of secretory product directly to the blood stream
Target organs:ReceptorsSignal transduction pathways
The endocrine glands
Pituitary gland (hypophysis)Thyroid gland (glandula thyroidea)Parathyroid gland (glandula parathyroidea)Adrenal/suprarenal gland (glandula suprarenalis)Pineal gland (corpus pineale)Pancreas: Langerhans-islets (insular apparatus)Ovarium: yellow body (corpus luteum)Testis: Leydig cells
The developmental origin of the endocrine glands
Ectoderm:Neuroectoderm:
neurohypophysiscorpus pineale
Neural crest:gl. thyroidea -parafollicular cells,gl. suprarenalis -medulla
Epithelium:Rathke s pouch: adenohypophysis
Mesoderm:gl. suprarenalis -cortex
Endoderm:Epithelium: gl. parathyroideaLangerhans islets
Slide 67, hypophysis, H&E, 4x
Neurohypophysis:Neurohypophysis:pars nervosapars nervosa
Adenohypophysis:Adenohypophysis:pars intermediapars intermedia
Adenohypophysis:Adenohypophysis:pars distalispars distalis
Slide 67, hypophysis pars nervosa, H&E, 40x
capillariescapillaries(fenestrated(fenestratedendothelium)endothelium)
pituicytespituicytes
endothelialendothelialcellcell
axons(hypothalamo-hypophyseal tract)
Slide 67, hypophysis pars intermedia, H&E, 40x
cyst filled with colloidcyst filled with colloid
simple cuboidal epitheliumsimple cuboidal epithelium
Slide 67, hypophysis pars distalis, H&E, 40x
acidophil cellsacidophil cellsbasophil cellsbasophil cells
chromophobe cellchromophobe cell
n. paraventricularis
n. supraopticus
axons(hypothalamo-hypophyseal tract)
optic tract
3rdventricle
Slide 85, hypothalamus, oxytocin immunocytochemistry, 4x
Slide 85, n. supraopticus, oxytocin immunocytochemistry, 40x
Slide 68, thyroid gland, H&E, 4x
connective tissue septum
follicles
Slide 68, thyroid gland, H&E, 40x
folliclefollicularepithelialcells
colloid(thyroglobulin)
capillary
Slide 69, parathyroid gland, H&E, 10x
oxyphil cellsoxyphil cells
chief cellschief cells
capillariescapillaries
Slides 69, parathyroid gland, H&E, 40x
oxyphil cellsoxyphil cells
chief cellschief cells
adipocytesadipocytes
Slide 70, adrenal gland, H&E, 4x
medullamedulla
cortexcortex
capsulecapsule
z. glomerulosaz. glomerulosa
z. reticularisz. reticularis
z. fasciculataz. fasciculata
Slide 70, adrenal gland - cortex, H&E, 10x
capsulecapsule
Slide 70, zona glomerulosa, H&E, 40x
endocrineendocrinecellscells
Slide 70, zona fasciculata, H&E, 40x
sinusessinuses
endocrineendocrinecellscells
Slides 70, zona reticularis, H&E, 40x
sinusessinuses
endocrine cellsendocrine cells
Slide 70, adrenal medulla, H&E, 40x
sinusessinuses
arteriolearteriole
chromaffin cellschromaffin cells
Slide 50, pancreas, H&E, 10x
exocrineexocrinepancreaspancreas
islets of Langerhansislets of Langerhans
septumseptum
lobuluslobulus
Slide 50, pancreas, H&E, 40x
islet of Langerhansislet of Langerhans
capillarycapillary
Slide 71, corpus luteum, H&E, 4x
ovarian cortexovarian cortex
corpus luteumcorpus luteum
folliclesfollicles
Slide 71, corpus luteum, H&E, 10x
thecatheca--lutein cellslutein cells
granulosagranulosa--lutein cellslutein cells
Slide 71, corpus luteum, H&E, 40x
thecatheca--lutein cellslutein cells
granulosagranulosa--lutein cellslutein cells
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