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BiologyMr. Karns

Excretory system

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Each kidney

Is supplied with blood by a renal artery and drained by a renal vein

Figure 44.13a

Posterior vena cava

Renal artery and vein

Aorta

Ureter

Urinary bladder

Urethra

(a) Excretory organs and major associated blood vessels

Kidney

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38–3 The Excretory System

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Functions of the Excretory System

Functions of the Excretory System

Every cell produces metabolic wastes.

The process by which these wastes are eliminated is called excretion.

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Functions of the Excretory System

The skin excretes excess water and salts in the form of sweat.

The lungs excrete carbon dioxide.

The kidneys also play a major role in excretion.

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Functions of the Excretory System

The Kidneys

What are the functions of the kidneys?

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Functions of the Excretory System

The kidneys:

• remove waste products from the blood.

• maintain blood pH.

• regulate the water content of the blood and, therefore, blood volume.

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The Kidneys

The kidneys are located on either side of the spinal column near the lower back.

A tube, called the ureter, leaves each kidney, carrying urine to the urinary bladder.

The urinary bladder is a saclike organ where urine is stored before being excreted.

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The Kidneys

Structure of the KidneysKidney Nephron

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The Kidneys

Blood enters the kidney through the renal artery.

The kidney removes urea, excess water, and other waste products and passes them to the ureter.

The clean, filtered blood leaves the kidney through the renal vein and returns to circulation.

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The Kidneys

Kidney Structure 

A kidney has two distinct regions:

• The inner part is called the renal medulla.

• The outer part is called the renal cortex.

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The Kidneys

Cortex

Medulla Renal artery

Renal vein

Ureter

To the bladder

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The Kidneys

The functional units of the kidney are called nephrons.

Nephrons are located in the renal cortex, except for their loops of Henle, which descend into the renal medulla.

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The Kidneys

Artery

Vein

Loop of Henle

Bowman’s capsule

Glomerulus

Capillaries

Collecting duct

To the ureter

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The Kidneys

Vein

Artery

Capillaries

To the ureter

Collecting duct

Each nephron has its own blood supply:

• an arteriole

• a venule

• a network of capillaries connecting them

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The Kidneys

Vein

Artery

Capillaries

To the ureter

Collecting duct

Each nephron releases fluids to a collecting duct, which leads to the ureter.

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The Kidneys

How is blood filtered and removed?

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Excretory Processes

Most excretory systems (4 basic parts)

Produce urine by refining a filtrate derived from body fluids

Figure 44.9

Filtration. The excretory tubule collects a filtrate from the blood.Water and solutes are forced by blood pressure across the selectively permeable membranes of a cluster of capillaries and into the excretory tubule.

Reabsorption. The transport epithelium reclaims valuable substances from the filtrate and returns them to the body fluids.

Secretion. Other substances, such as toxins and excess ions, are extracted from body fluids and added to the contents of the excretory tubule.

Excretion. The filtrate leaves the system and the body.

Capillary

Excretorytubule

Filtrate

Urine

1

2

3

4

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What are the 4 parts?

Say it outloud

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Key functions of most excretory systems are

1. Filtration, pressure-filtering of body fluids producing a filtrate

2. Reabsorption, reclaiming valuable solutes from the filtrate

3. Secretion, addition of toxins and other solutes from the body fluids to the filtrate

4. Excretion, the filtrate leaves the system

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The Kidneys

As blood enters a nephron through the arteriole, impurities are filtered out and emptied into the collecting duct.

The purified blood exits the nephron through the venule.

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The Kidneys

The mechanism of blood purification involves two distinct processes: filtration and reabsorption.

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The Kidneys

Filtration 

Passing a liquid or gas through a filter to remove wastes is called filtration.

The filtration of blood mainly takes place in the glomerulus.

The glomerulus is a small network of capillaries encased in the top of the nephron by a hollow, cup-shaped structure called Bowman's capsule.

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The Kidneys

Fluid from the blood flows into Bowman’s capsule.

The materials filtered from the blood include water, urea, glucose, salts, amino acids, and some vitamins.

Plasma proteins, cells, and platelets remain in the blood because they are too large to pass through the capillary walls.

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The Kidneys

Reabsorption 

Most of the material removed from the blood at Bowman's capsule makes its way back into the blood.

The process in which liquid is taken back into a vessel is called reabsorption.

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The Kidneys

Almost 99% of the water that enters Bowman’s capsule is reabsorbed into the blood.

When the filtrate drains in the collecting ducts, most water and nutrients have been reabsorbed into the blood.

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The Kidneys

Remaining material, called urine, is emptied into a collecting duct.

Urine is primarily concentrated in the loop of Henle.

The loop of Henle is a section of the nephron tubule in which water is conserved and the volume of urine minimized.

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The Kidneys

As the kidney works, purified blood is returned to circulation while urine is collected in the urinary bladder.

Urine is stored here until it is released from the body through a tube called the urethra.

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Control of Kidney Function

Control of Kidney Function “Homeostasis”

The activity of the kidneys is mostly controlled by the composition of the blood.

In addition, regulatory hormones are released in response to the composition of blood. This is controlled by a hormone ADH from the Pituitary Gland.

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Pituitary Gland feedback system

Pituitary Gland

What is the function of the pituitary gland?

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Pituitary Gland – master control

The pituitary gland secretes nine hormones that directly regulate many body functions and controls the actions of several other endocrine glands.

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Pituitary Gland

The pituitary gland is a structure at the base of the skull.

The gland is divided into two parts: the anterior pituitary and the posterior pituitary.

Remember anterior – front side or ventral

posterior- toward the rear / dorsal side

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Pituitary Gland

The Pituitary Gland

Hypothalamus

Pituitary gland

Posterior pituitary

Anterior pituitary

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Pituitary Gland

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Control of Kidney Function

When you drink a liquid, it is absorbed into the blood through the digestive system.

As a result, the concentration of water in the blood increases.

As the amount of water in the blood increases, the rate of water reabsorption in the kidneys decreases.

Less water is returned to the blood, and excess water is sent to the urinary bladder to be excreted as urine.

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Control of Kidney Function

When the kidneys detect an increase in salt, they respond by returning less salt to the blood by reabsorption.

The excess salt the kidneys retain is excreted in urine, thus maintaining the composition of the blood.

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Antidiuretic hormone (ADH)

Increases water reabsorption in the distal tubules and collecting ducts of the kidney

Figure 44.16a

Osmoreceptorsin hypothalamus

Drinking reducesblood osmolarity

to set point

H2O reab-sorption helpsprevent further

osmolarity increase

STIMULUS:The release of ADH istriggered when osmo-receptor cells in the

hypothalamus detect anincrease in the osmolarity

of the blood

Homeostasis:Blood osmolarity

Hypothalamus

ADH

Pituitarygland

Increasedpermeability

Thirst

Collecting duct

Distaltubule

(a) Antidiuretic hormone (ADH) enhances fluid retention by makingthe kidneys reclaim more water.

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Kidney Disorders

Kidney Disorders

Humans have two kidneys, but can survive with only one.

If both kidneys are damaged by disease or injury, there are two options:

• a kidney transplant

• kidney dialysis

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Kidney Disorders

Kidney dialysis works as follows:

• Blood is removed by a tube and pumped through special tubing that acts like nephrons.

• Tiny pores in the tubing allow salts and small molecules to pass through.

• Wastes diffuse out of the blood into the fluid-filled chamber, allowing purified blood to be returned to the body.

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Kidney Disorders

Kidney Dialysis

Air detector

Dialysis machine

Fresh dialysis fluid

Compressed air

Vein

Artery

Shunt

Blood pump

Blood in tubing flows through dialysis fluid

Used dialysis fluid

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38–3

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A dialysis machine performs the function of which structure in the excretory system?

a. nephron

b. ureter

c. urethra

d. glomerulus

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In the human body, the kidneys play an important role in

a. producing digestive enzymes.

b. circulating the blood.

c. destroying old red blood cells.

d. maintaining homeostasis.

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In the nephron, most filtration occurs in the

a. renal tubule.

b. capillaries.

c. glomerulus.

d. loop of Henle.

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Urine leaves the body through the

a. loop of Henle.

b. glomerulus.

c. urethra.

d. bladder.

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Materials filtered out of the blood include all of the following EXCEPT:

a. water.

b. urea.

c. amino acids.

d. plasma proteins.

END OF SECTION

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