Disorders of menstruation

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DISORDERS OF MENSTRUATION

Sherin shana Govt.College of Nursing

Kozhikode

AMENORRHEA

ABSENCE OF MENSTRUATION IN WOMEN IN

REPRODUCTIVE AGE

CRYPTOMENORRHEA

• Menstruation occurs but there is obstruction

to the outflow of blood

• CAUSES Congenital: Imperforate hymen

Acquired: Vaginal atresia,

cervical stenosis

PATHOPHYSIOLOGY

Accumulation of blood in uterine cavity

Hematocolpos

Hematometra

Hematosalphinx

CLINICAL FEATURES

• Amenorrhea

• Lower abdominal pain

• Retention of urine

• Uniform globular mass in the abdomen

• Bulging hymen

MANAGEMENT

• Cruciate incision of hymen and drainage of

blood

• Dialatation of cervix in stenosis

PRIMARY AMENORRHEA

• Failure of onset of menstruation beyond the

age of 16 in a girl with normal secondary

characteristics

CAUSES

Disorders of Hypothalamo Pituitary Ovarian Axis

A. Hypogonadotrophic hypogonadism

- Delayed puberty

- CNS Tumors

- Hypothalamic and pituitary dysfunction

B. Hypergonadotrophic hypogonadism

-Primary ovarian failure

-Galactosemia

-17alpha hydroxlase deficiency

Abnormal chromosomal pattern

eg:Turners syndrome

Developmental defect of genital tract

eg: absence of vagina,absence of uterus

Dysfunction of thyroid gland

Metabolic disorders

Systemic illness

INVESTIGATIONS

• History & Physical examination

• Ultrasonography

• Karyotyping

• Hormonal studies

• Blood investigations

MANAGEMENT

• Correction of the cause

• Cyclic estrogen and progesterone

• Corticosteroid therapy

SECONDARY AMENORRHEA

• Absence of menstruation for 6 months or

more in a women with previous normal

menstrual patterns.

ETIOLOGY• Uterine factors• Ovarian factors• Pituitary factors• Hypothalamic factors• Systemic• Adrenal disorders

INVESTIGATIONS

• History & physical examination

• Blood investigations

• Hormonal studies

MANAGEMENT

1) No abnormality detected• Assurance2) Cases with detectable cause• Treat the underlying cause3) Polycystic ovarian syndrome• Weight reduction• GnRH agonist• Surgery

4) Hyperprolactinemia• Bromocriptine• Surgery5) Premature ovarian failure• Hormonal therapy• Corticosteroids• IVF

6) Adrenal disorders

• Adrenocorticolytic drug

• Adrenalectomy

DYSMENORRHEA

• PAINFUL CRAMPING PAIN ACCOMPNYING

MENSTRUATION

CLASSIFICATION

PRIMARY DYSMENORRHEA

SECONDARY DYSMENORRHEA

OTHER TYPES

SPASMODIC

CONGESTIVE

MEMBRANOUS

PRIMARY DYSMENORRHEA

• Painful menstruation with no pelvic pathology

• Usually starts 2-3 yrs after menarche and ceases after child birth.

• Begins shortly before or at the onset of menses and lasts one or three days

CAUSES

Psychosomatic factorsAbnormal anatomical and functional aspects

of uterus -Stenosis at internal oss - Unequal development of mullerian

duct -Inappropriate law of polarityRole of vasopressin

PATHOPHYSIOLOGY

CLINICAL FEATURES

Uterine cramping

Nausea

Vomiting

Fatigue

Diarrhea

Headache

Giddiness

DIAGNOSIS

• Pelvic sonography

• CT/MRI

• Hysterosalphingography

• Hysteroscopy/Laproscopy

TREATMENT

GENERAL MEASURES

1. Counseling

2. Psychotherapy

DRUGS

1. Prostaglandin synthetase inhibitors:

eg:Mefanamic acid,Ibuprofen,Indomethacin

2. Oral Contraceptives

eg:Dydrogesterone

SURGERY

Dilatation of cervical canal

Presacral Neurectomy

Laser Assisted uterosacral Nerve Ablation

SECONDARY DYSMENORRHEA

Associated with presence of pelvic pathology

Cramp starts 3 to 5 days prior to menstruation

and relieves with start of bleeding

Patients are usually thirties

CAUSES

Chronic pelvic infection

Endometriosis

Adenomyosis

Uterine fibroid

IUCD in utero

Endometrial polyp

PATHOPHYSIOLOGY

Pain is due to pelvic congestion which is more marked in the premenstrual period.

Pain increases in its severity as menstruation approaches and is relieved by the onset of menstrual flow, due to the diminution of pelvic congestion.

CLINICAL FEATURES

Dull aching lower abdominal pain

accompanied by backache

Dyspareunia

Infertility

Abnormal bleeding

TREATMENT

Treat the cause rather than symptomSurgical interventions Diagnostic hysteroscopy followed by D&C Diagnostic laparoscopy Laprotomy followed by excision of

adenomyoma Hysterectomy in elderly

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