Cyberinfrastructure for CHOIS a Global Health initiative for obesity surveillance and control
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National University Community Research Institute (NUCRI)
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Cyberinfrastructure for CHOIS a Global Health initiative
for obesity surveillance and control
Arun K. Datta1, Victoria Jackson2, Radha Nandkumar3, and Weimo Zhu4
1National University2Illinois Department of Human Services3National Center for Supercomputing Applications4University of Illinois at Urbana-Champaign
National University Community Research Institute (NUCRI)
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NU Community Research Institute (NUCRI)
• National School Board (NCC/FRC)
• HASTAC (higher education)/HASS grid
• UC Humanities Research Institute
• K12 (AmeriCorps)• ARTCA• Illinois Department of Public
Health• NCSA/University of Illinois at
Urbana-Champaign• SmileHealthy, SIU, SALTRA, etc.focused on digital technology need based
Research for the community
NUCRI is an outreach to the Community for National University
(http://nucri.nu.edu)
National University Community Research Institute (NUCRI)
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NU Community Research Institute (NUCRI)
(http://nucri.nu.edu)
i-Dataware – web based integrated database system for providing social services
ezSRB – web based interface for managing data through Storage Resource Broker (SRB) middleware; used in HASSgrid deployment
VCMSS – virtual collaboratory tool for working on collaborative projects
FastApps – web based software system for grant management
CyberEdWorld – immersive 3D space for virtual classroom
Open source software technologies (Portal Technology, Content management Software/Drupal, audio/video communication software/Access Grid, PHP, MySQL…)
Tools and Technologies
National University Community Research Institute (NUCRI)
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https://ncc.nu.edu/
National University Community Research Institute (NUCRI)
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CHOIS
Electronic Medical Record System
Supported by CI
Childhood Obesity Informatics System
National University Community Research Institute (NUCRI)
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Electronic Medical Record
By 2014, all the citizens should have an access to his/her Electronic Medical Record.
Communications of the ACM, Nov 2009, Vol 52 (11), 18-20.
EMR are widespread in Europe, Australia, and elsewhere, but only 4% of American doctors have a fully functional system.
New England J. med., 356, 24, June 14, 2007, 2527 – 34.
National University Community Research Institute (NUCRI)
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Information flow commonly present
National University Community Research Institute (NUCRI)
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Implementing Electronic Medical Record
• Benefits are obvious• Reduction of clerical errors • Clinical-decision support• Furthering medical research
• Economic Incentives to doctors• Economic Incentives to Hospitals
• Regulations – HIPAA, FERPA• Standards (HL 7, ISO, DICOM, etc.)• Data Integration• Data exchange
Communications of the ACM, Nov 2009, Vol 52 (11), 18-20.
National University Community Research Institute (NUCRI)
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Data Integration
CT finding, Epithelial carcinoma of the ovary
X-ray
HematologyElectronic Medical Record Electronic Healthcare RecordOral Pathology HistopathologyBlood tests
Image of acute arterial embolism
Microarray
Scanning Tunneling Microscopy
Transmission electron microscopy
Atomic force microscope (AFM)
Heart surgery
National University Community Research Institute (NUCRI)
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Echocardiography (EKG)
Tablet-PC
Smart Phone
Electronic Devices for capturing the data
National University Community Research Institute (NUCRI)
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• EHR will be in place by 2014
• Health information exchange policy will be in place
• Medical devices will be standardized to send the data to the EHR and ‘connect’ to each other
• Patient will have a greater control over his/her health data
• Patients will have more control over surveillance system
• More meaningful reports can be generated using CI
• Users needs to be trained for appropriate use of EHR
CI in Healthcare Management
National University Community Research Institute (NUCRI)
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National University Community Research Institute (NUCRI)
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Obesity – a Global Concern
U.S. National Health and Nutrition Examination Survey suggests almost 1/3 of children and adolescents are overweight or obese and 11.3% of children and adolescents are very obese.
Since last two decades, it has become so common that in 1997 the World Health Organization (WHO) formally recognized it as a global epidemic.
National University Community Research Institute (NUCRI)
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The economic impact of this condition is staggering: in 2008, it has been estimated that more than 147 billion dollars were spent just in the United States for medical costs related to obesity and this estimation does not include the time lost from work. If this trend continues, it has been projected that nearly one-fifth of the healthcare budget in US alone may have to be used for obesity control [1,2]. Due to all these, obesity has become a major concern in US.
The present administration under President Obama has recently established a task force on childhood obesity (White house, February 09, 2010).
1. Wang Y, Beydoun MA, Liang L, Caballero B, Kumanyika SK. Obesity, 16 (2008), 2323-30
2. Hammond RA. Prev Chronic Dis. 6 (2009). Retrieved on February 14, 2010 from http://www.cdc.gov/pcd/issues/2009/jul/09_0017.htm.
National University Community Research Institute (NUCRI)
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A 2006 review identified ten possible contributors to the recent increase of obesity [1]. Obesity is the result of interplay between genetic and environmental factors. Polymorphisms in various genes controlling appetite and metabolism predispose to obesity when sufficient calories are present. As of 2006, more than 41 of these sites have been linked to the development of obesity when a favorable environment is present [2].
A sedentary lifestyle obviously plays a significant role in obesity.
1. Keith, T. Genetic Engineering and Biotechnology News, 27 (2), Jan 15 20072. Poirier P, Giles TD, Bray GA, et al. Arterioscler. Thromb. Vasc. Biol. 26 (2006), 968–76.
National University Community Research Institute (NUCRI)
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http://nucri.nu.edu/obesity/index.php
National University Community Research Institute (NUCRI)
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Por
tal U
ser
Inte
rface
Grid ResourceBroker Service
Grid and Web
Protocols
Informationand
Data Services
DatabaseService Database
HPCor
Compute Cluster
Grid InformationServices, SRB
PortalClientStub
PortalClientStub
PortalClientStub
JDBC,Local, orRemote
Connection
Three-tiered service oriented architecture is accepted standard for accessing Grid and other services
Three-Tier Architecture
National University Community Research Institute (NUCRI)
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Grid Portals
Launch, configureAnd control Application Interface
Workflow service
Open Grid Service Architecture Layer
Open Grid Service Infrastructure (web service component model) Resource layer
(slide by Dennis Gannon, modified)
Distributed Grid and Web Services
Registries and Name Binding
Reservations and Scheduling
Policy
Event/Mesg Services
security
Administrating & Monitoring
logging
Data Management services
Account services
Grid Orchestration
App InstanceApp InstanceApp Instance
National University Community Research Institute (NUCRI)
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Data grid deployment
National University Community Research Institute (NUCRI)
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Visualization of SRB
Mainframes
Supercomputers
Any platformDistributed Server
SQL server/Oracle/MySQL
National University Community Research Institute (NUCRI)
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National University Community Research Institute (NUCRI)
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http://nucri.nu.edu/DHS/login.php
CHOIS – Childhood Obesity Informatics System
National University Community Research Institute (NUCRI)
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CHOIS – Childhood Obesity Informatics System
Features of CHOIS- Web based forms
* BMI, Asthma, etc* Genomic info
- Combination of federated and central databases- Reports are available from anywhere anytime- Role based accessibility- Regulatory compliance (HIPAA, FERPA)- Mobile version is available- CMS, Drupal- Data integrator & DSS
Cyberintegrator, MotifNetwork, etc.- Alert system- Cyberenvironments
National University Community Research Institute (NUCRI)
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CHOIS
Web application Tools
DSS
Alert systemCyberIntegrator
NutrigramActivitygram
Training materials
Research International Collaboration
Immersive 3D Space
*Accessible through computers and smart phones
Child Health and Obesity Informatics System
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demo
National University Community Research Institute (NUCRI)
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CHOIS – Child Health and Obesity Informatics System
Incorporating Genomic Information
National University Community Research Institute (NUCRI)
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CHOIS – Content Management System, Drupal
http://nucri.nu.edu/DHS/drupal/
National University Community Research Institute (NUCRI)
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CHOIS
Thank You
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