Clinical Research Center at a Glance Lynda Lane MS Administrative Director.

Clinical Research Center at a Glance

Lynda Lane MS

Administrative Director

Clinical Research CenterClinical Research Center• Funded through a grant from the National

Center for Research Resources – NIH for the past 53 years. Formerly the GCRC.

• Purpose: to provide infrastructure support for clinical research.

• Part of the Clinical and Translational Science Award (CTSA)

• Access resources and support through the StarBRITE website. www.mc.vanderbilt.edu/starbrite

Vanderbilt Institute for Clinical and Translational Research (VICTR)

• Establish physical and virtual home for translational investigation

• Stimulate/streamline communications and remove impediments

• Develop a new generation of investigators

• Actively develop novel methodologies

Gordon Bernard, MD

CTSA PI

Clinical and Translational Research Center FacilitiesClinical Research Center

•19 bed Inpatient and Outpatient facility •Located on hospital space – S 3100 MCN

Pediatric Clinical Research Center•6 Room Outpatient clinic•Located in the Vanderbilt Children’s Hospital Clinic 9th Floor DOT

Clinical Trials Center•2 room outpatient clinic•Office space for 15 research personnel •Located at the Village at Vanderbilt •New office at 100 Oaks Mall

CRC Investigators by

Department

Nursing Core• MCN location Staffed 24/7

• Pedi CRC staffed M-F

• 26 Full time inpatient and outpatient nurses

• 2 Unit clerk

• 2 administrative support staff

Cardiovascular Physiology

• Autonomic Testing System• Vascular and Cerebral Doppler• Microneurography System• Echocardiograph - Ultrasound• ECG• Forearm Blood Flow Systems• Tilt Table• EndoPat

Energy Balance and Exercise Physiology

• Bicycle Ergometers ● Treadmills

• Metabolic Carts

• DXA Scanner

• Metabolic Chamber

• BodPod

• Bioelectrical Impedance

• Activity Monitors

Bionutrition Assessment

• Metabolic Kitchen– Controlled nutrient meals

• Dieticians for meal planning

• Food analysis software

Informatics Lab

• Poster Printing

• Physiological Equipment Development

• Computer and software Support

Assay Development and Core Lab

• Imaging Satellite

• PET Imaging

• fMRI - 3 and 7 tesla

•Two inpatient rooms configured for sleep monitoring systems

•EEG•Polysomnograms•Multiple sleep latency

Sleep Research Core

What can the CRC Provide ?

• Pilot funding support

• Inpatient and outpatient space and nursing care

• Ancillary support for pilot projects

Grant Budget Planning for VICTR / CRC resources

• For grant budget planning, if you are submitting an investigator-initiated proposal funded by a federal grant, agency, or foundation, you may assume that the following support is available to you at no cost from the VICTR Clinical Research Center

Clinical Research Center and Pediatric CRC

• CRC Space and Nursing• Centrifuge Use• Dry Ice for Shipping Samples• Freezer Space for Short-Term Sample Storage• Inpatient Space and Nursing Care• Outpatient Nursing Care on CRC • Outpatient Space on CRC• Pediatric Outpatient Nursing on Pedi CRC• Pediatric Outpatient Space on Pedi CRC• Ultrasound Technician CRC

Nutrition Services

• Diet Assessment - Outpatient

• Diet Instruction - Outpatient

• Food Records and Food Recalls Training

• Nutrition Counseling

• Nutrition Data System - Training

• Nutrition Data System for Research - Use

• Regular Meal/Snack

• Special Nutrient Controlled Meal

• Study Diet Development

Physiologic Measurement

• Metabolic Cart• 24 Hour Energy Expenditure

(Chamber)• Actigraphy• Actigraphy set up• Bioelectrical Impedance• Bod Pod• DEXA• Doppler Blood Flow Equipment

• EKG Without Interpretation

• Echocardiograph Equipment

• Exhaled Nitric Oxide Analyzer

• Forearm Blood Flow Equipment

• Physical Activity Monitoring Pedometers

• Tilt Testing

• Treadmill Testing -VO2 Max

Grant Management

• Must avoid double-dipping• OK to state in grant proposal that

Vanderbilt has a CRC that provides support.

• Can get letter of support for grant proposals

Vanderbilt Institute for Clinical & Translational Research (VICTR) Supported Weekly Clinics

a No registration necessary.b Email notification of upcoming attendance helpful – contact biostat-clinic@list.vanderbilt.edu.c See http://biostat.mc.vanderbilt.edu/Clinics for more details, including daily themes.d By appointment – contact Erica Bowton, erica.bowton@vanderbilt.edu.e Contact Veida Elliott, veida.elliott@vanderbilt.edu, for available session dates.f See http://www.mc.vanderbilt.edu/crc/workshop.html for schedule of topics & presenters.

How do I get support?

StarBRITE

• www.mc.vanderbilt.edu/starbrite

• www.mc.vanderbilt.edu/crc