Transcript

Human Biology (BI 104-01)

Instructor: Dr. Zhe Xu

zhexu007@yahoo.com

Levels of Biological Organization

atom

molecule

cell

tissue

organ

organ system

organism

Basic Chemistry (Inorganic)• Atom

– Atoms are the basic units of elements– 96% of human body: OCHN

Periodic Table of The Elements

– Each atom consists of a nucleus and orbiting electrons

Helium (He)

nucleus

electron

• Nucleus– Proton: “+” charged, atomic mass = 1 unit– Neutron: uncharged, atomic mass = 1 unit

• Electron shell– Electrons: “-” charged, atomic mass 0 unit

Atoms are electrically neutral

Atomic mass = proton mass + neutron mass

Atomic number = the number of protons

All atoms of an element have the same number of protons

atomic mass 4

atomic number 2He atomic symbol

– Isotopes• Atoms of the same element that differ in the

number of neutrons

126

Carbon 12C

136

Carbon 13C

146

Carbon 14C

(radioactive)

147

Nitrogen 14Ndecay

– Electron shells• The innermost shell holds up to 2 electrons.• The outermost shell (valence shell) is most

stable with 8 electrons (rule of eights)

• Chemical bonds– Ionic bond

Electrons are transferred from one atom to another• Anion: gain electrons, negatively charged• Cation: lose electrons, positively charged

– Covalent bond: share electrons between atoms to meet the rule of eights

hydrogen gas (H2)

oxygen gas (O2)

water (H2O)

nonpolar

polar

– Hydrogen bond: attraction between electropositive H and electronegative O or N.

polar molecule

• Properties of H2O: all attribute to hydrogen bond

– High heat capacity: • Water temperature rises and falls slowly

– High heat of vaporization: • Vaporization of water requires lots of heat

– Solvent:• Dissolves ionized and polar molecules

– Cohesive and adhesive:• Water molecules adhere to each other and polar surfaces

– High surface tension:

– Ice is less dense than liquid H2O

• BufferA chemical or a combination of chemicals that keeps pH within normal limits, usually weak acids or weak bases.

– Acids • Dissociate in water and release H+

• Strong acid: Dissociation is almost complete.HCl → H+ + Cl-

• Weak acid: Dissociation is minimal.

(carbonic acid) (bicarbonate ion)H2CO3 H+ + HCO3

-

– Bases • Either take up H+ or release OH-

• Strong base: Dissociation is almost complete

NaOH → Na+ + OH-

• Weak base: Dissociation is minimal

ammonia ammonium ion

NH3 + H2O NH4+ + OH-

– pH scale• Measurement scale for hydrogen ion concentration

• pH = -(log10 [H+])

0 7 14acid base

[H+](moles per liter)

pH

1 x 10-6 6

1 x 10-7 7

1 x 10-8 8

Study Guide• Which four element make up the bulk of living matter?• Name the elements: O, C, H, N, Ca, P, K, Na, Cl, I, Fe.• What is the nucleus of an atom composed of?• What type of charge do protons carry?• Do neutrons have charge?• What type of charge do electrons carry?• What is the atomic number?• What is the atomic mass?• What are isotopes?• An atom is inert when its valence shell contain ____ electrons.• What type of chemical bond exists in table salt (NaCl) and O2?• What type of chemical bond contributes to the special properties of

water?• What is the scale of pH? What pH is acidic? What pH is alkaline?

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