B. pseudomallei : Role of MALDI-TOF

B. pseudomallei: Role of MALDI-TOF

Rob BairdRoyal Darwin Hospital

MALDI-TOF

What is MALDI TOF?Role of MALDI TOF – current evidenceWhere does it fit in the current/future

diagnostic algorithms?

VITEK 2 Resistance

Serology

VITEK 2 Resistance

Serology

MALDI -TOF

5 Minutes

Rapid Result deliveryby MALDI TOF

Identifies > 96% of clinically relevant pathogensResults within minutesCost less than 50 cents/isolate (compared to $5.00 isolate currently)

Replaces over 20 current biochemical identification assaysIdentification down to species levelIdentifies bacteria & fungi

Next generation Direct detection out of blood cultures/wound swabs

Provisional susceptibility profiles

MALDI-TOF and Burkholderia

2007

2013

2013