AAHC ELG mtg dec 2012 - Open Platforms for Collaborative Discovery
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Open Platforms forCollaborative Discovery
richard j. bookmanrbookman@miami.edu
2012 AAHC ELG MeetingWashington, DC6 December 2012
NIH Purchasing Power – 2003-2013
2003 2004 2005 2006 2007 2008 2009 2010 2011 2012 2013 Senate
$18
$20
$22
$24
$26
$28
$30
$32
$27.1$27.9 $28.5 $28.5
$29.0 $29.3
$30.5$31.0 $30.7 $30.6 $30.7
$26.9 $26.4
$25.3$24.8
$23.9 $24.2$23.9
$23.0$22.4
$21.9
Current Constant (BRDPI)
Bill
ion
s
Labor-HHS BA only
Sources: NIH Budget Office; House and Senate Appropriations Committees
NIH Purchasing Power – 2003-2013
Labor-HHS BA onlySources: NIH Budget Office; House and Senate Appropriations Committees
Over the past decade, before pursuing a particular line of research, scientists (including C.G.B.) in the haematology and oncology department at the biotechnology firm Amgen in Thousand Oaks, California, tried to confirm published findings related to that work. Fifty-three papers were deemed 'landmark' studies. It was acknowledged from the outset that some of the data might not hold up, because papers were deliberately selected that described something completely new, such as fresh approaches to targeting cancers or alternative clinical uses for existing therapeutics. Nevertheless, scientific findings were confirmed in only 6 (11%) cases. Even knowing the limitations of preclinical research, this was a shocking result.
you may ask yourself…
…how did we get here?
research 1.0who’s doing research?
how is research organized?
how is research communicated?
who’s paying for research?
Newton Darwin Einstein
research 1.0who’s doing research?
how is research organized?
how is research communicated?
who’s paying for research?
research 2.0who’s doing research?
how is research organized?
how is research communicated?
who’s paying for research?
research 2.0who’s doing research?
how is research organized?
how is research communicated?
who’s paying for research?
research 2.0who’s doing research?
how is research organized?
how is research communicated?
who’s paying for research?
internet
disintermediation
reintermediation
2012: a tipping point year?
50% of all US book* sales are e-books
Online movie views surpass in-theatre views
3-D printers fall below $1000
Majority of computers sold are smartphones
* non-textbook sales
& self-replicate!
research 3.0
?
Our challenge
“Institutions seek to preserve the problem for which they are the solution.”
- Clay Shirky
Research 3.0who’s doing research?
how is research organized?
how is research communicated?
who’s paying for research?
design
spe
c
Research 3.0who’s doing research?
how is research organized?
how is research communicated?
who’s paying for research?
design
spe
c
Research 3.0who’s doing research?
how is research organized?
how is research communicated?
who’s paying for research?
design
spe
c
Research 3.0who’s doing research?
how is research organized?
how is research communicated?
who’s paying for research?
design
spe
c
3 = 1 + 2
3 > 1 + 2
platforms:weatherGPSgoogle maps
re-useful is the new useful
open platforms for
collaborative discovery
end
Some emerging trends in research communications
http://altmetrics.orghttp://force11.orghttp://www.executablepapers.com/
orphans
”…a new platform can be said to succeed when your customers and partners build new features before you do.”
Tim O’Reilly
Vannevar Bush
NIH Grant Success RatesFY 1978-2012
2012: 1.0 megapub per year…
…and that’s just medline.
source: David Browdy, Northwestern
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