7´$S b$Ug b&ì Ø Â L S u T7´ ö b Â l g u - | b 6 ~ 6õ M %Ê'2 · +0[ '¨>/'v %Ê'2 b*ü í% $× \%Ê'2 2

2011 2006

80 5070 1-2-1

201-2-2

2014 2014

27 1300

NPO PID NPO PNH

CAPS CAPS

TSH PRL

NPO SCD MSA

NPO PADM

* 60 10287

61 2600 62 400 63 24100 64 1100 65 1383

40 5881 41 700 42 43 44 1942 45 1800 46 6255 47 7109 48 10000 49 60122 50 19500 51 27800 52 10146 53 66300 54 4800 55 500 56 18636 106 100 107 5400 108 TNF 100

72 ADH 1900 73 TSH 200 74 PRL 2600 75 600 76 400 77 3000 78 8400 79 140 80 3000 81 1800 82 1000 83 1000

1 960 2 9096 3 712 4 175 5 8100 6 108803 7 3500 8 851

* 9 100

10 6250 11 19670 12 100 13 17073 14

15 1000 16 340 17 11733 18 ( ) 25447 19 911 20 193 21 1087 22 15177 23 475 24 83 25 100 26 HTLV- 3000 27 200 28 1802 29 300 30 400 31 100 32 100 33 100

38 90 27158

19 911 21 1087 57 25233 58 3144 59 24

84 23088 85 7367 86 2299 87 100 88 1810 89 526 110 100

91 252 92 900 93 19701 94 400 95 10000 96 36418 97 143733 98 5000

* 99 1400

100 100 101 100

34 3588 35 5279 36 347 37 1843 38 39 51 27800 52 10146

68 2360 69 33346 70 5147 71 15388

66 Ig 33000 67 29000 109 100

102 200 103 CFC 200 104 100 105 5000

26 9 12 9 10 6

10 2710 11 27

500 500 500

CIDP 400 280

250 NPO 210

180 PKD 170

135 122

NPO PADM 122 NPO PID 95 NPO PNH 77 PAH 200 IBD 500

RP 70 270 500 280 20 30

CAPS 8 55 20

600 6,094

H26.9.4

14(1)(2) 13 16 18 27

22 (3)

14(3) 15(1)

17 26 19 28

20(2) 29(2)

(1)(2) 32

5,789 2,439 42.117 75

2-2- 2 1/2

2-2- 2 2/2

48% 5510

10 71%32

55 4582%

1 12 31 34 2,117 18 65 2,323 18 7410

10 13 16 (18 74 ) 1,282 10 17 21 26 30 (18 74 ) 1,648

17 21 1,587 26 30 237 10 22 29 (18 74 ) 735

4533 30

2-3-1(1)

2-3-1(2)

2-3-1(3)

2-3-1(4)

2-3-1(5)

2-3-1(6)

2-3-1(7)

2-3-1(8)

2-3-1(9)

2-3-1(10)

2-3-1(11)

2-3-1(12)

2-3-1(13)

2-3-1(14)

2-3-1(15)

2-3-1(16)

2-3-1(17)

2-3-1(18)

2-3-1(19)

2-3-1(20)

2-3-1(21)

2-3-1(22)

2-3-1(23)

2-3-1(24)

2-3-1(25)

2-3-1(26)

2-3-1(27)

2-3-1(28)

2-3-1(29)

2-3-1 n=2,117

0% 50% 100%

12 18 34 45

0 1 120 30

10 1 CIDP

2-3-8 1

2-3-10 /

2-3-11 /

2-3-12

2-3-13

2-3-2 (n=2,117)

0% 50% 100%

2-3-3 [ ] (n=72)

2-3-4 [ ] (n=10)

0% 50% 100%

2-3-5 [ ] (n=25)

2-3-6 [ ] (n=38)

0% 50% 100%

2-3-7 [ ] (n=363)

2-3-8 [ ] (n=75)

0% 50% 100%

2-3-9 [ ] (n=75)

2-3-10 [ ] (n=11)

0% 50% 100%

2-3-11 [ ] (n=46)

2-3-12 [ ] (n=218)

0% 50% 100%

2-3-13 [ ] (n=642)

2-3-14 [ ] (n=310)

0% 50% 100%

2-3-15 [ ] (n=35)

2-3-16 [ ] (n=36)

0% 50% 100%

2-3-17 [ ] (n=191)

2-3-18 [ ] (n=62)

0% 50% 100%

2-3-19 [ ] (n=99)

2-3-20 [ ] (n=19)

++----

0% 50% 100%

2-3-21 1 n=2,117

0% 50% 100%

2-3-22 n=2,117

0% 50% 100%

2-3-23 ( n=2,117

0% 50% 100%

2-3-24 n=2,117

0% 50% 100%

2-3-25 n=2,117

(n=162) (n=129)

0% 50% 100%

(n= 47) (n= 42)

(n= 32) (n= 28)

(n= 45) (n= 40)

(n= 39) (n= 18)

(n= 13) (n= 13)

(n= 9) (n= 8) (n= 8)

(n= 8) (n= 8)

(n= 6) (n= 4)

24 (n= 4) (n= 2)

(n= 81) (n= 74) (n= 40)

(n= 31) (n= 19)

(n= 42) (n= 20)

(n= 17) (n= 11)

(n= 10) (n= 9)

(n= 6) (n= 5)

(n= 4) (n= 5)

(n= 23) (n= 20)

(n= 10) (n= 4)

(n= 3)

2-3-26 n=2,117

0% 50% 100%

2-3-27 n=2,117

0% 50% 100%

etc38 39 2 3 etc 35

& & 19

2 1 & 47

2 3 15 & 62

1 ( & 43 )

PC ( 33 ) ( &

( 32 ) (

( 65 )

( 45 )

( 40 )

(& 28 )

( 55 )

( 22 )

( 43 )

( 45 )

( & 48 )

( 20 )

( 40 )

2F 136(

( 44 )

( 36 )

2 3( PRL 42 )

1 2 3 1 ( 34 )

( 41 )

4 5( 55 )

( & 61 )

2 ( 61 )

( 49 ) 20

( 61 ) ( 65 )

( 38 )

( 45 )

( 44 ) 3 4 5 ( & 37 )

( 42 ) ( & 52 )

500 ( 48 )

( 50 )

( 66 )

( 46 )

( 58 ) (

& & 59 )

( 49 ) PC ( 64 )

( 43 )

( 19 )

( 39 )

( 46 ) ( 45 )

4 5 ( 58 )

1 ( 45 ) (n= 9)

( 44 ) ( &

( 34 )

( 61 )

( 34 )

( 62 ( ))

( 45 )

( & 32 )

( 26 )

( 24 )

( 41 ) (

37 ) 5 8 (

41 ) 10 2 3 1

( 53 )

( 37 )

(n= 3)

( & 60 ) ( 68 ( ))

( 61 )

( 65 )

PC ( 35 )

( 58 )

( 40 )

( 19 )

( 41 )

( 30 )

1( 38 )

( 50 )

( 38 )

( 60 ) ( 50

( 47 )

( 32 )

1 ( 63 )

( & 33 )

( 73 ( )) 3 ( 39 )

( & 54 ) ( 48 )

2 ( 40 ) 1

( 45 )

( 55 )

( 45 )

1 ( 53 )

( 47 ( ))

( & 54 )

( 30 )

( 27 ) (

52 ) ( 26 )

( 64 )

( 48 )

( & 62 )

2 ( 60 )

( 62 )

30 ( & 45 )

( 52 ) ( 61 ( ))

( 47 )

( 64 )

( 70 )

2 ( 44 )

( 58 )

( 46 )

64 15 2-3-152-3-17 15 2-3-18

2-3-14

18 12 34

2-3-15 2-3-17

2-3-15 /

2-3-16 /

2-3-17 /

2-3-18

2-3-19 2-3-24 15

10 12 14 15

2-3-19

2-3-20

-0.04 0.14 0.07 -0.24 -0.11 -0.110.06 -0.06 -0.22 -0.09 0.20 -0.24

-0.08 -0.13 0.28 -0.04 -0.21 -0.12 -0.040.05 0.24 -0.11 0.14 -0.18 -0.11 -0.17

-0.12 -0.08 0.90 -0.09 -0.04 -0.02-0.13 -0.12 0.24 -0.12 -0.10 -0.08 0.09

-0.08 -0.09 -0.04 -0.06 -0.14 0.87-0.13 -0.04 -0.06 -0.08 -0.10 0.88 -0.18

-0.06 -0.14 0.32 -0.26 -0.10 0.86 -0.090.07 0.18 -0.13 0.14 -0.06 -0.06 -0.05

-0.06 -0.07 0.09 -0.08 -0.17 -0.18-0.09 -0.04 0.12 -0.12

0.16 -0.06 -0.23 -0.10 -0.07-0.09 -0.12 -0.070.16 -0.10 0.060.15 -0.18 -0.14 -0.07 -0.08

-0.08 0.32 0.34 -0.12 -0.12 -0.070.08 0.14 -0.14 0.13 -0.06 -0.05 -0.04

-0.12 -0.07 0.89 -0.08 -0.04 -0.03-0.11 -0.14 0.37 -0.14 -0.08 0.74 -0.04

-0.10 -0.10 -0.07 -0.10 0.86 -0.17

-0.05 0.84 0.09 -0.07 -0.07 0.05-0.03 0.11 0.85 0.07 -0.22 -0.07

-0.20 0.11 0.28 -0.08 0.28 -0.07-0.03 -0.12 0.05 -0.45 -0.09 -0.36-0.05 -0.04 -0.06 -0.08 -0.04-0.03 -0.06 -0.04 -0.10 0.03 0.90 0.07-0.19 -0.04 -0.16 -0.04-0.15 -0.06 -0.10 -0.10 0.07

-0.15 0.05 -0.18 0.08-0.11 -0.10 -0.13 0.08 0.860.97 -0.11 -0.12 -0.10

0.05 0.54 0.06 -0.13 -0.07-0.11 0.06 -0.29 -0.09

-0.11 -0.12 -0.170.11 -0.05 -0.16

-0.07 -0.12 -0.09-0.25 -0.07 -0.11

-0.11 -0.10 -0.15 0.09 0.84-0.04 -0.03 -0.05 -0.08 -0.03

-0.14 -0.14 0.05 -0.12 0.07-0.14 -0.07 -0.12 -0.08

2-3-21

2-3-22

0.22 -0.05 -0.20 -0.30 -0.07 0.08 0.12 0.18

0.07 -0.05 -0.27 -0.04 -0.09 -0.04 -0.06

0.22 -0.24 -0.13

0.11 -0.07 -0.06 -0.28 0.05

0.30 0.11 0.10 0.05 -0.070.09 0.05 0.09 -0.130.05 0.72 0.14 -0.08 0.31 -0.14 0.14 0.18

0.93 0.18 0.02 0.16 -0.13 0.040.04 0.97 0.11 -0.02 0.16

0.07 0.14 0.84 -0.05 0.14 -0.04-0.08 -0.15 -0.60 0.07 -0.11 0.03

-0.10 0.23 0.06 -0.18 0.08 -0.06

0.12 0.45 0.11 -0.06 0.07 0.62 0.07

0.47 0.13 0.18 0.18 0.16

-0.14 0.38 0.17 0.18 -0.14

0.05 0.13 0.09 -0.10 0.140.24 0.07 -0.07 -0.06 -0.05 -0.190.14 -0.08 -0.03 -0.14 0.03 -0.05 -0.03

0.09 -0.03 -0.27 -0.06 0.23 0.12-0.03 0.07 -0.04 -0.14 -0.03 0.16 0.05-0.04 -0.03 0.19 -0.250.06 -0.34 -0.05 0.06 0.37

2-3-23

-0.060.06 -0.12 -0.07

-0.05 0.11 0.05 -0.19 -0.10 -0.110.10 0.11 -0.06

-0.070.12 -0.07

-0.12 -0.09 -0.14 -0.08 0.19 -0.21 -0.040.27 0.07 -0.19 0.07 -0.07 0.11

0.06-0.07 -0.14 0.24 -0.05 -0.20 -0.11 -0.06

0.14 -0.06-0.06 -0.06 -0.06

0.13 -0.15 -0.09 -0.08-0.29 -0.11 0.10 -0.14 -0.130.64 0.10 0.05 -0.12

0.29-0.08 -0.07 0.24

0.03 -0.09 -0.08 0.82 -0.09

0.06-0.12 -0.11 0.22 -0.10 -0.11 -0.07 0.05

0.10 -0.05 0.090.14

-0.08 0.25-0.09 -0.09 0.30-0.04 -0.08 -0.10 0.80

-0.05 0.24 -0.07-0.06 -0.05 -0.07 0.21 -0.07-0.14 -0.05 -0.07 -0.08 0.42 -0.14

0.06 -0.10 -0.05 0.79 -0.040.13

-0.05 0.11 -0.12 0.34-0.05 -0.17 0.27 -0.21 -0.09 0.69 -0.08

0.08 0.12 -0.13 0.34

0.06 -0.13 0.12 -0.070.31 0.06 -0.04

-0.05 -0.04 -0.11 -0.110.08 -0.05 -0.09 -0.11

-0.06 -0.04 -0.08 -0.10

2-3-24

0.13 0.060.34

-0.05 0.71 0.08 -0.06 -0.070.22

-0.06 0.07 0.21 0.060.22 -0.08 -0.07

0.10 0.66 0.06 -0.19 -0.080.36 -0.06

-0.05-0.18 0.09 0.26 -0.08 0.26 -0.06-0.08 0.08 0.10 0.10

-0.08-0.09 -0.23 -0.17-0.06 -0.28 -0.05 -0.22

0.06 -0.12 -0.04 -0.14

-0.04 -0.04 -0.05 -0.06 -0.03

0.19-0.10 -0.04 -0.08 0.05 0.77 0.060.14 -0.06 -0.07 0.41

-0.05-0.08

-0.10 -0.08-0.14 -0.03 -0.11 -0.04-0.12 0.09

-0.05 -0.05-0.11 -0.07 0.05-0.03 -0.05 -0.04 -0.14 0.04 -0.06

0.06-0.06

-0.13 0.04 -0.16 0.05-0.04 -0.06 0.05

-0.06 0.230.10

-0.08 -0.08 -0.12 0.06 0.65-0.06 -0.06 0.04 0.480.150.63 -0.07 -0.05 -0.080.37 -0.06 -0.11 -0.050.66 -0.06 -0.06

2-3-28

0% 50% 100%

2-3-29

2-3-30

0% 50% 100%

(n=760)

(n=569)

(n=400)

(n=191)

(n=32)

(n=179)

0% 50% 100%

(n=760)

(n=569)

(n=400)

(n=191)

(n=32)

(n=179)

2-4-1 n=2,117

0% 50% 100%

2-4-2 n=2,117

2-4-3 n=89

2-4-4 n=426

2-4-5 n=168

0% 50% 100%

2-4-6 n=116

0% 50% 100%

2-4-1 10

2-4-7 n=1,282

8.2% 24.6% 26.2% 19.7% 3.3% 21.3% 6114.7% 21.6% 24.7% 17.8% 7.3% 18.5% 25911.4% 4.5% 18.2% 25.0% 9.1% 34.1% 4412.2% 12.9% 16.7% 23.3% 8.2% 30.9% 5026.3% 14.1% 6.3% 28.1% 4.7% 40.6% 6419.4% 27.8% 5.6% 22.2% 2.8% 25.0% 3613.8% 13.8% 17.2% 24.1% 0.0% 31.0% 298.6% 16.7% 24.7% 25.8% 7.0% 18.3% 18611.5% 13.5% 14.6% 30.2% 9.4% 25.0% 966.2% 7.7% 16.9% 18.5% 7.7% 46.2% 6515.0% 5.0% 20.0% 30.0% 5.0% 25.0% 2015.4% 22.1% 31.7% 25.0% 5.8% 6.7% 10415.9% 2.4% 18.3% 24.6% 5.6% 38.1% 12618.2% 15.2% 13.6% 16.7% 10.6% 33.3% 667.9% 9.2% 18.4% 27.6% 14.5% 25.0% 7614.3% 9.1% 23.4% 16.9% 2.6% 37.7% 778.4% 29.0% 12.1% 26.2% 9.3% 19.6% 1076.8% 1.7% 16.9% 20.3% 8.5% 49.2% 596.6% 14.8% 4.9% 29.5% 4.9% 39.3% 619.2% 13.8% 9.2% 29.2% 12.3% 29.2% 6513.4% 17.9% 23.9% 20.9% 6.0% 19.4% 674.6% 20.7% 27.6% 29.9% 5.7% 11.5% 8711.5% 15.4% 18.6% 23.2% 7.3% 27.1% 1,282

--0% 50% 100%

1 2 4 8 16 32 32 <

2-4-8 n=1,282

13.1% 3.3% 6.6% 1.6% 41.0% 34.4% 613.5% 8.5% 16.2% 1.9% 35.1% 34.7% 2599.1% 6.8% 11.4% 0.0% 18.2% 54.5% 447.2% 3.6% 12.2% 1.8% 24.1% 51.2% 5021.6% 1.6% 7.8% 0.0% 29.7% 59.4% 642.8% 2.8% 16.7% 2.8% 38.9% 36.1% 3613.8% 3.4% 6.9% 3.4% 34.5% 37.9% 297.0% 8.1% 13.4% 2.2% 38.7% 30.6% 1865.2% 8.3% 15.6% 0.0% 27.1% 43.8% 966.2% 3.1% 7.7% 0.0% 15.4% 67.7% 655.0% 0.0% 5.0% 0.0% 40.0% 50.0% 204.8% 12.5% 16.3% 1.0% 36.5% 28.8% 104

11.9% 1.6% 7.1% 0.0% 17.5% 61.9% 1267.6% 3.0% 13.6% 1.5% 25.8% 48.5% 662.6% 3.9% 13.2% 5.3% 23.7% 51.3% 763.9% 3.9% 18.2% 0.0% 22.1% 51.9% 776.5% 7.5% 12.1% 2.8% 32.7% 38.3% 1076.8% 0.0% 8.5% 0.0% 13.6% 71.2% 591.6% 1.6% 8.2% 0.0% 29.5% 59.0% 616.2% 6.2% 13.8% 0.0% 27.7% 46.2% 657.5% 9.0% 13.4% 1.5% 35.8% 32.8% 679.2% 10.3% 16.1% 3.4% 37.9% 23.0% 876.4% 4.9% 12.3% 1.6% 29.9% 44.9% 1,282

0% 50% 100%

2-4-9 16 n=1,282

2-4-10 n=1,282

0% 50% 100%

10 401 25 CIDP

15 11.6

2-4-10

2-4-11

2-4-12

11.2 7.0

2-4-13

2-4-11

2935 40

2-4-14

2-4-12 n=1,977

0% 50% 100%

2-4-13 n=1,977

0% 50% 100%

2-4-14 n= 735

0% 50% 100%

60 30 15

2-4-15 n=735

2-4-15

0% 50% 100%

23.3% 60.0% 16.7% 33.3% 50.0% 16.7% 3031.3% 55.8% 12.9% 27.9% 55.1% 17.0% 14721.7% 65.2% 13.0% 34.8% 47.8% 17.4% 2337.0% 36.8% 26.2% 33.0% 37.3% 29.6% 35134.3% 28.6% 37.1% 34.3% 17.1% 48.6% 3530.0% 40.0% 30.0% 40.0% 30.0% 30.0% 1047.1% 35.3% 17.6% 35.3% 41.2% 23.5% 1730.0% 60.0% 10.0% 30.0% 50.0% 20.0% 8029.4% 47.1% 23.5% 29.4% 47.1% 23.5% 3432.5% 40.0% 27.5% 27.5% 22.5% 50.0% 4038.5% 38.5% 23.1% 46.2% 30.8% 23.1% 1325.4% 62.7% 11.9% 23.7% 61.0% 15.3% 5943.2% 32.0% 24.8% 40.0% 31.2% 28.8% 12524.4% 46.3% 29.3% 36.6% 34.1% 29.3% 4140.0% 34.0% 26.0% 32.0% 34.0% 34.0% 5041.7% 43.8% 14.6% 33.3% 52.1% 14.6% 4824.5% 39.6% 35.8% 15.1% 45.3% 39.6% 5330.6% 38.9% 30.6% 25.0% 22.2% 52.8% 3633.3% 30.3% 36.4% 33.3% 18.2% 48.5% 3321.4% 50.0% 28.6% 14.3% 57.1% 28.6% 1426.7% 70.0% 3.3% 30.0% 60.0% 10.0% 3021.9% 65.6% 12.5% 25.0% 56.3% 18.8% 3233.7% 44.6% 21.6% 31.6% 41.5% 26.9% 735

2-4-16

2-4-17

235 2-4-19 5

2-4-20

2-4-18

2-4-19

2-4-20

14(1)(2) 1621 5 2-4-225 2-4-23

2-4-21

50 50 50

2-4-22

2-4-23

18 20(1) 27 29(1)24 7 2-4-25,

2-4-26 7 2-4-27

2-4-24

2-4-25

2-4-26

2-4-27

21.4% 21.7% 22.5% 18.3% 12.8%

.859 -.044 -.027 .089 -.101

.821 .026 .099 -.033 -.149

.764 -.037 -.172 .011 .154

.580 .113 .146 .044 -.069

.567 -.079 -.049 -.085 .314

.559 .089 .143 .018 .057-.078 .928 -.041 .013 -.009

.004 .894 -.016 -.002 -.004

.116 .821 -.036 -.058 .024-.042 .698 .110 .022 .009.018 -.005 .851 -.010 -.046

-.042 .022 .821 .032 .075

.004 -.038 .784 -.052 .029

.007 .006 .784 .020 .066

.010 -.088 .063 .881 -.042-.033 .052 .007 .854 -.001.032 -.003 .006 .830 .017.049 .016 -.080 .701 .028

-.063 -.026 .151 .042 .834.076 .048 -.026 -.029 .823

10.2% 5.0%

.870 -.125

.749 .063-.226 .831.342 .578

1.000 .483 .486 .294 .441 .195 .061.483 1.000 .535 .416 .303 .268 .059.486 .535 1.000 .464 .323 .296 .090.294 .416 .464 1.000 .230 .327 .127.441 .303 .323 .230 1.000 .190 .102.195 .268 .296 .327 .190 1.000 .030.061 .059 .090 .127 .102 .030 1.000

24 246 2-4-29 2-4-30 6

2-4-31

2-4-28

2-4-29 1 3 6

2-4-30 4 6 6

2-4-31

19.5% 10.5% 8.0%

.800 -.040 .009

.782 .028 .028

.777 -.062 .067

.767 .026 -.014

.735 .020 .055

.716 .041 -.098

.704 -.034 -.067

.701 .009 .099

.045 .755 .026

.020 .717 .088-.091 .677 .157-.012 -.570 .456-.007 .223 .602

.076 -.116 .598

.108 .219 .539-.032 .510 .519-.057 -.095 .471

8.3% 7.8% 7.2%

.836 -.031 .025

.822 -.030 .056-.057 .855 .004.002 .810 .008.014 .001 .819.001 -.032 .697.309 .097 .430

1.000 .171 .047 .135 .145 .035.171 1.000 .044 -.019 .156 -.166.047 .044 1.000 -.019 -.072 .170.135 -.019 -.019 1.000 -.019 .254.145 .156 -.072 -.019 1.000 -.058.035 -.166 .170 .254 -.058 1.000

2-4-32

2-4-33

2-4-34

10100 20

2-5-1 n=2,117

0% 50% 100%

48.8 40 65 6 18 39 340

2-5-2 n=2,117

0% 50% 100%

18 34 35 50 51 65

2-5-3 n=2,117

0% 50% 100%

10100 20

2-5-4 (n=1,083)

2-5-5 (n=108)

2-5-6 (n=249)

++++++

----------

0% 50% 100%

------

0% 50% 100%

2-5-7 (n=486)

100 299 300 499 500 999 25 26

2-5-8 n=2,117

++++++

0% 50% 100%

-------

0% 50% 100%

100 100 299 300 499 500 999 1000

2-5-9 (n=1,083)

2-5-10 (n=108)

13.9% 54.4% 23.8% 12.1% 34.5% 3.2% 7.8% 0.9% 1,083

10.9% 56.3% 29.7% 9.4% 26.6% 3.1% 6.3% 6.3% 64

11.1% 28.7% 17.6% 4.6% 59.3% 7.4% 20.4% 2.8% 108

13.7% 44.6% 20.1% 14.1% 44.2% 5.6% 7.6% 0.4% 249

8.0% 63.0% 13.6% 20.0% 30.0% 2.9% 7.6% 1.6% 4865.9% 17.8% 1.5% 4.4% 15.6% 1.5% 1.5% 61.5% 13511.7% 51.7% 19.5% 13.2% 34.4% 3.5% 7.9% 5.1% 2,117

----------

0% 50% 100%

++++ ++

0% 50% 100%

2-5-11 (n=249)

2-5-12 (n=486)

2-5-13 n=2,117

0% 50% 100%

++++++

0% 50% 100%

2-5-14 n=2,117

0% 50% 100%

2-5-15 n=2,117

7.9% 19.1% 37.1% 12.4% 79.8% 0.0% 2.2% 6.7% 3.4% 13.5% 893.1% 26.5% 45.3% 7.5% 77.0% 3.8% 1.6% 2.1% 1.2% 11.0% 42610.5% 14.5% 40.8% 0.0% 71.1% 2.6% 3.9% 0.0% 5.3% 14.5% 766.0% 17.9% 29.4% 5.0% 65.5% 3.3% 2.6% 1.3% 3.4% 23.0% 9066.3% 24.2% 26.3% 7.4% 23.2% 1.1% 3.2% 1.1% 11.6% 31.6% 95

13.3% 11.1% 40.0% 4.4% 84.4% 2.2% 4.4% 4.4% 6.7% 4.4% 453.6% 12.5% 44.6% 1.8% 73.2% 1.8% 0.0% 1.8% 1.8% 17.9% 566.9% 22.1% 37.0% 9.2% 81.3% 9.5% 3.8% 2.7% 2.7% 8.8% 2622.9% 30.1% 25.0% 7.4% 64.0% 2.2% 2.9% 0.0% 3.7% 19.9% 1368.4% 27.1% 26.2% 7.5% 83.2% 9.3% 6.5% 2.8% 1.9% 12.1% 1074.3% 17.4% 26.1% 4.3% 84.8% 2.2% 2.2% 2.2% 0.0% 10.9% 464.2% 29.2% 54.8% 8.3% 73.2% 3.6% 2.4% 3.0% 2.4% 11.9% 1684.5% 17.0% 27.4% 6.3% 74.0% 4.0% 3.6% 0.9% 4.9% 16.6% 2236.3% 23.2% 32.1% 4.5% 75.0% 4.5% 2.7% 0.9% 0.9% 14.3% 1125.6% 13.2% 30.6% 6.9% 51.4% 3.5% 0.7% 2.8% 3.5% 31.9% 144

12.5% 16.9% 35.3% 5.1% 80.9% 4.4% 4.4% 2.2% 1.5% 12.5% 1363.0% 23.4% 25.4% 3.0% 57.4% 1.5% 3.0% 1.5% 4.1% 31.0% 1977.1% 26.5% 25.5% 7.1% 82.7% 8.2% 6.1% 3.1% 1.0% 13.3% 985.6% 24.4% 25.6% 7.8% 23.3% 1.1% 3.3% 1.1% 12.2% 31.1% 902.3% 26.1% 15.9% 5.7% 53.4% 2.3% 4.5% 0.0% 5.7% 27.3% 88

12.1% 27.3% 35.4% 9.1% 81.8% 8.1% 3.0% 1.0% 4.0% 8.1% 995.2% 17.2% 35.3% 5.2% 87.1% 12.9% 5.2% 3.4% 0.9% 8.6% 1165.6% 20.8% 33.9% 6.0% 70.1% 4.0% 2.7% 1.9% 3.3% 17.4% 2,117

0% 50% 100%

30%15%

2-5-16 n=2,117

0% 50% 100%

2-5-17 n=1,083

2-5-18 n=108

2-5-19 n=249

0% 50% 100%

2-5-20 n=486

2-5-21 n=2,117

0% 50% 100%

2-5-22 (n=1,282 )

2-5-23 (n=1,282 )

0% 50% 100%

2-5-24 (n=1,282 )

0% 50% 100%

30 25 2010

35% 35

2-5-25 n=1,977

0% 50% 100%

2-5-26 n=1,977

0% 50% 100%

5 5 49 50 299 300 999 1000 2999 3000

2-5-27

1 89.1

2-5-28

2-5-29

2-5-30 n=1,977

P.227230

0% 50% 100%

3 41 3

(1) (1) 30 40

30 25 2010

2-5-31 n=1,977

0% 50% 100%

2-5-32 n=1,977

0% 50% 100%

(2) (2)

2-5-33 n=1,977

0% 50% 100%

(3) (3) 35

2-5-34 n=1,977

0% 50% 100%

(4) (4)

2-5-35 n=1,977

0% 50% 100%

2-5-36 (n=765 )

2-5-37 n=54

2-5-38 n=64

2-5-39 n=63

2-5-40 n=64

0% 50% 100%

242-5-6 2-5-7

2-5-6 1 5 9

2-5-7 6 9 9

10 22 24

2413 2-5-10 2-5-12 13

2-5-13

2-5-10 1 4 13

2-5-11 5 9 13

2-5-12 10 13 13

2-5-13

242-5-15 2-5-18

2-5-19

2-5-14

2-5-15 1 4 20

2-5-16 5 9 20

2-5-17 10 15 20

2-5-18 16 20 20

2-5-19

2-5-20

1 9(1)(2)

31 32 155 2-5-22 5

2-5-23

2-5-21

2-5-22

2-5-23

1 9(1)(2) 31 32

155 2-5-25 2-5-26 5

2-5-27

2-5-24

2-5-25 1 5 8

2-5-26 6 8 8

2-5-27

2-5-28

2-5-29

(.378) (.120)

(.095) (.093)

(.043)

(.143) (.072)

(.119)

(.111)

(.062)

(.053) (.047)

(.131) (.113)

(.058) (.054)

(.049) 45 (.048)

(.044)

(.334)

(.066)

(.118)

(.096)

(.054)

(.183) (.137)

(.068) 12 (.061)

(.044) (.038)

(.036)

(.165)

(.144) (.098)

(.088)

(.069)

(.067)

(.040)

(.115)

(.055) (.053)

13 18 (.265)

(.158) (.050)

(.044)

(.080) (.041)

(.079) (.052) (.044) (.044)

A(.188)

(.138) (0.77)

2-6-1 ( p<0.01 p<0.05 --,- )

--------

------

++++++++

------

++++++

------

--------

------------------

0% 50% 100%

2-6-2( p<0.01 p<0.05 --,- )

----------

++++++++

+++++++

-------

++++++++++++++

++++----

0% 50% 100%

(18 ) 13 18

( p<0.01 p<0.05 --,- )

0% 50% 100%

( p<0.01 p<0.05 --,- )

++++++++

------

--------

0% 50% 100%

( p<0.01 p<0.05 --,- )

++++++++

+-------

------

++++++

------

----------

--------

++++++++++++++

++++++++++++++++++

---------------

-------------------------

0% 50% 100%

(.172) (.095)

(.073) (.062)

(.118)

(.108)

(.101) (.093) (.083)

(.069) (.061)

(.295)

(.144) (.091) (.067)

(.062) 34 (.062)

(.105) (.073)

(.060)

(.056)

(.171) (.123)

(.123)

(.060)

(.189)

(.088)

(.083) 35 (.216)

(.084)

(.075) (.059)

(.137) (.068)

(.066) A (.062)

(.057)

(.175) 34 (.121)

(.056)

(.081) (.095)

(.068)

(.096)

(.089) (.082)

(.070)

(.068)

(.057)

(.167) 1

(.076)

(.097)

(.096)

(.070)

(.408) (.115)

(.060)

50 50 50

( p<0.01 p<0.05 --,- )

----------

------

++++++

++++++++

0% 50% 100%

( p<0.01 p<0.05 --,- )

-------

+++++++

++++++++

--------

++++++++

++++++

------

++++++++++++

---------

0% 50% 100%

( p<0.01 p<0.05 --,- )

0% 50% 100%

(.314) (.264)

(.152)

(.087) (.069)

(.062)

(.112)

(.075)

(.069)

(.047)

(.125)

(.098)

(.073)

(.109) (.104)

(.230)

(.069) (.062)

(.057) (.054)

(.049) (.041)

(.171)

(.169)

(.069) A

(.058) (.054)

(.053)

(.082)

(.081)

(.052)

(.314) (.091)

(.200)

(.110)

(.100)

(.100) (.050)

(.046)

(.076) (.056)

(.138)

(.157)

(.052)

(.310)

(.113) (.070)

(.063)

(.048)

(.047)

(.041)

(.168) (.096)

(.095)

(.082) 13

(.058)

(.123)

(.115)

(.071)

(.054) (.053)

(.297) (.142)

(.055)

(.047)

(.042)

(.064)

(.048)

(.047)

(.045) (.032)

(.028) (.027)

(.088)

(.050)

(.044) (.038)

(.744)

(.048) (.043)

35 (.114)

(.087) (.085)

(.076)

(.053) (.044)

(.176)

(.095)

(.073) (.055)

(.119)

(.077)

2-8-10

2-8-11

2-8-12

2-8-13

2-8-14

2-8-15

2-8-16

2-8-17

2-8-18

2-8-19

2-8-20

2-8-21

2-8-22

( p<0.01 p<0.05 --,- )

--------

----++++

++++++++

--------

------

+++++++++

0% 50% 100%

( p<0.01 p<0.05 --,- )

------

----+++++++

++++++++++

++++++++++++

------

--+++++

0% 50% 100%

( p<0.01 p<0.05 --,- )

++++++++++

+++++++++

--------

++++++++

--------

0% 50% 100%

( p<0.01 p<0.05 --,- )

--------------

--------

------

++++++

0% 50% 100%

( p<0.01 p<0.05 --,- )

++++++

-++++++

------

+++++++

++++++

0% 50% 100%

2-8-7 n=149

2-8-8 n=621

0% 50% 100%

+++++++++

0% 50% 100%

2-8-9 n=473

2-8-10 n=168

2-8-11 n=207

2-8-12 n=109

++++++

0% 50% 100%

2-8-13 n=75

2-8-14 n=893

2-8-15 n=631

2-8-16 n=126

0% 50% 100%

++++++

0% 50% 100%

2-8-17 A n=20

2-8-18

( p<0.01 p<0.05 --,- )

0% 50% 100%

(.262)

(.260)

(.095) (.094)

(.171) (.101)

B (.092) (.079)

(.106)

(.086)

(.262)

35 (.196)

(.130)

(.120)

(.095)

(.155)

(.153) (.143)

(.135)

(.132)

(.128)

(.110) (.067)

(.141)

(.123) (.093)

(.091)

(.123) (.109)

A (.106) (.096)

(.136)

(.074) (.103)

(.089)

(.086)

(.116)

(.162) (.131)

(.110)

(.105)

(.199) (.178)

(.129) (.128)

(.103)

(.119)

(.104)

(.150)

(.096) (.081)

(.121)

2-9-10

2-9-11

2-9-12

2-9-13

2-9-14

2-9-15

2-9-16

50 2-9-17

2-9-18

( p<0.01 p<0.05 --,- )

0% 50% 100%

( p<0.01 p<0.05 --,- )

0% 50% 100%

2-10-1

2-10-2

2-10-3

2-10-4

2-10-5

2-10-6

0.314 0.264-0.112 -0.075

0.297-0.142

On-Off

403 1 1

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