49 - eprints.unwahas.ac.ideprints.unwahas.ac.id/1529/7/LAMPIRAN.pdf · Mesin Tablet Single Punch (Tipe TDP-6) Friability Tester (Tipe CS2) Tablet Hardness Tester (Tipe YD-1) Alat-alat
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49
Lampiran 1. Hasil Determinasi Tumbuhan Saga
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Lampiran 1. Lanjutan...
51
Lampiran 2. Surat Keterangan telah Melakukan Penelitian
52
Lampiran 2. Lanjutan...
53
Lampiran 3. Hasil Uji Sifat Fisik Granul Tablet Hisap Ekstrak Etanol Daun
Saga
a. Waktu Alir Granul (detik)
Replikasi Kecepatan alir (gram/detik)
F I F II F III F IV F V
1 10,8 10.10 9,52 8,93 8,13
2 10,9 10.10 9,90 9.17 8,33
3 10,9 10,10 9,90 9,17 8,33
Rata-rata 10,86 10,10 9,77 9,09 8,26
SD 0,057 0 0,030 0,138 0,115
b. Sudut Diam (0)
Replikasi Sudut Diam (
o)
F I F II F III F IV F V
1 25,46 22,61 21,03 21,03 14,92
2 23,49 22,61 21,61 22,80 16,5
3 22,61 22,61 22,80 21,61 17,1
Rata-rata 23,85 22,61 21,81 21,81 16,17
SD 1,459 0 0,790 0,790 1,126
c. Kompresibilitas (%)
Replikasi Sudut Diam (
o)
F I F II F III F IV F V
1 16 11 10 7 6
2 13 11 10 8 6
3 13 10 10 7 6
Rata-rata 14 10,6 10 7,3 6
SD 1,73 0,57 0 0,57 0
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Lampiran 4. Hasil Uji Keseragaman Bobot Tablet Hisap
a. Keseragaman Bobot
Replikasi Keseragaman Bobot (mg)
F I F II F III F IV F V
1 808 799 808 799 821
2 811 798 799 798 784
3 799 805 803 790 820
4 801 817 805 798 819
5 822 811 815 800 816
6 798 809 825 795 800
7 801 816 791 814 804
8 805 809 803 803 786
9 802 811 799 801 821
10 812 806 789 790 830
11 812 812 788 811 804
12 805 803 807 812 811
13 818 792 795 803 810
14 816 799 801 795 788
15 822 811 788 825 792
16 806 819 814 790 815
17 807 807 820 801 813
18 798 819 818 812 801
19 793 811 809 829 779
20 800 802 811 802 799
Rata-rata 806,8 807,8 804,4 803,4 805,65
SD 8,25642 7,37421 10,90340 10,81617 14,34637
%CV 808 799 808 799 821
Formula I
Bobot rata-rata 20 tablet = 806,8 mg
Penyimpangan 5% =
× 806,8 mg = 40,34 mg
Range penyimpangan = (766-847) mg
Penyimpangan 10% =
× 806,8 mg = 80,68 mg
Range penyimpangan = (726-887) mg
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Lampiran 4. Lanjutan...
Formula II
Bobot rata-rata 20 tablet = 807,8 mg
Penyimpangan 5% =
× 807,8 mg = 40,39 mg
Range penyimpangan = (767-848) mg
Penyimpangan 10% =
× 807,8 mg = 80,78 mg
Range penyimpangan = (727-889) mg
Formula III
Bobot rata-rata tablet = 804,4 mg
Penyimpangan 5% =
× 804,4 mg = 40,22 mg
Range penyimpangan = (764-845) mg
Penyimpangan 10% =
× 804,4 mg = 80,44 mg
Range penyimpangan = (724-885) mg
Formula IV
Bobot rata-rata tablet = 803,4 mg
Penyimpangan 5% =
× 803,4 mg = 40,17 mg
Range penyimpangan = (763-844) mg
Penyimpangan 10% =
× 803,4 mg = 80,5
Range penyimpangan = (723-884) mg
Formula V
Bobot rata-rata tablet = 805,65 mg
Penyimpangan 5% =
× 805,65 mg = 40,28
Range penyimpangan = (765-846) mg
Penyimpangan 10% =
× 805,65 mg = 80,57 mg
Range penyimpangan = (725-886) mg
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Lampiran 5. Hasil Uji Kekerasan Tablet Hisap
Replikasi Kekerasan (kg)
F I F II F III F VI F V
1 6 8.2 9.4 10.1 12.9
2 7.4 7.9 8.4 11.3 12.9
3 7 8.8 8.9 11.5 11.5
4 8.9 8.1 9.6 9.9 12.4
5 8.6 9.1 9.6 11.4 11.2
Rata-rata 7.62 8.42 9.18 10.84 12.18
SD 1.123 0.506 0.521 0.773 0.791
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Lampiran 6. Hasil Uji Statistik Kekerasan Tablet Hisap
Variables Entered/Removedb
Model
Variables
Entered
Variables
Removed Method
1 Formulaa . Enter
a. All requested variables entered.
b. Dependent Variable: kekerasan
Model Summary
Model R R Square
Adjusted R
Square
Std. Error of the
Estimate
1 .987a .974 .965 .343763
a. Predictors: (Constant), konsentrasipengikat
ANOVAb
Model Sum of Squares df Mean Square F Sig.
1 Regression 13.317 1 13.317 112.692 .002a
Residual .355 3 .118
Total 13.672 4
a. Predictors: (Constant), konsentrasipengikat
b. Dependent Variable: kekerasan
Coefficientsa
Model
Unstandardized Coefficients
Standardized
Coefficients
t Sig. B Std. Error Beta
1 (Constant) -4.200 1.314 -3.198 .049
konsentrasipengikat .231 .022 .987 10.616 .002
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Lampiran 7. Hasil Uji Kerapuhan Tablet Hisap
Kerapuhan tablet =
× 100 %
Replikasi Kerapuhan (%)
F I F II F III F IV F V
1 0.712 0.660 0.475 0.325 0.236
2 0.778 0.619 0.479 0.351 0.274
3 0.829 0.606 0.452 0.313 0.253
Rata-rata 0,773 0,628 0,469 0,318 0,254
SD 0,059 0,028 0,015 0,019 0,019
Formula I
1. Wo = 15,728 gr
Wa = 15,616 gr
Kerapuhan =
× 100%
= 0,712%
2. Wo = 15,684 gr
Wa = 15,562 gr
Kerapuhan =
× 100%
= 0,778%
3. Wo = 15,677 gr
Wa = 15,547 gr
Kerapuhan =
× 100%
= 0,829%
Formula II
1. Wo = 15,890 gr
Wa = 15,785 gr
Kerapuhan =
×100%
= 0,660%
2. Wo = 15,987 gr
Wa = 15,888 gr
Kerapuhan =
× 100%
= 0,619%
3. Wo = 16,335 gr
Wa = 16,236 gr
Kerapuhan =
× 100%
= 0,606%
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Lampiran 7. Lanjutan....
Formula III
1. Wo = 15,986 gr
Wa = 15,910 gr
Kerapuhan =
× 100%
= 0,475%
2. Wo = 15,862 gr
Wa = 15,786 gr
Kerapuhan =
× 100%
= 0,479%
3. Wo = 15,944 gr
Wa = 15,872 gr
Kerapuhan =
× 100%
= 0,452%
Formula IV
1. Wo = 15,993 gr
Wa = 15,941 gr
Kerapuhan =
× 100%
= 0,325%
2. Wo = 15,975 gr
Wa = 15,919 gr
Kerapuhan =
× 100%
= 0,351%
3. Wo = 15,978 gr
Wa = 15,928 gr
Kerapuhan =
× 100%
= 0,313%
Formula V
1. Wo = 16,134 gr
Wa = 16,096 gr
Kerapuhan =
× 100%
= 0,236%
2. Wo = 16,048 gr
Wa = 16,004 gr
Kerapuhan =
× 100%
= 0,274%
3. Wo = 16,192 gr
Wa = 16,151 gr
Kerapuhan =
× 100%
=0,253
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Lampiran 8. Hasil Uji Statistik Kerapuhan Tablet Hisap
Variables Entered/Removedb
Model
Variables
Entered
Variables
Removed Method
1 formulaa . Enter
a. All requested variables entered.
b. Dependent Variable: kerapuhan
Model Summary
Model R R Square
Adjusted R
Square
Std. Error of the
Estimate
1 .991a .983 .977 .032305
a. Predictors: (Constant), konsentrasipengikat
ANOVAb
Model Sum of Squares df Mean Square F Sig.
1 Regression .182 1 .182 174.119 .001a
Residual .003 3 .001
Total .185 4
a. Predictors: (Constant), konsentrasipengikat
b. Dependent Variable: kerapuhan
Coefficientsa
Model
Unstandardized Coefficients
Standardized
Coefficients
t Sig. B Std. Error Beta
1 (Constant) 2.106 .123 17.061 .000
konsentrasipengikat -.027 .002 -.991 -13.195 .001
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Lampiran 9. Hasil Uji Waktu Melarut Tablet Hisap
Replikasi Waktu Melarut (menit)
F I F II F III F IV F V
1 8,44 8,56 12,04 14,19 19,72
2 8,51 8,92 10,56 15,76 17,23
3 8,13 10,12 11,67 16,19 19,57
4 7,89 9,87 11,32 13,28 20,23
5 7,69 9,42 12,43 13,43 18,68
Rata-rata 8,13 9,38 11,66 14,57 19,09
SD 0,351 0,647 0,611 1,337 1,178
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Lampiran 10. Hasil Uji Statistik Waktu Melarut Tablet Hisap
Variables Entered/Removedb
Model
Variables
Entered
Variables
Removed Method
1 formulaa . Enter
a. All requested variables entered.
b. Dependent Variable: waktumelarut
Model Summary
Model R R Square
Adjusted R
Square
Std. Error of the
Estimate
1 .976a .952 .936 1.115483
a. Predictors: (Constant), konsentrasipengikat
ANOVAb
Model Sum of Squares df Mean Square F Sig.
1 Regression 73.495 1 73.495 59.065 .005a
Residual 3.733 3 1.244
Total 77.228 4
a. Predictors: (Constant), konsentrasipengikat
b. Dependent Variable: waktumelarut
Coefficientsa
Model
Unstandardized Coefficients
Standardized
Coefficients
t Sig. B Std. Error Beta
1 (Constant) -19.966 4.262 -4.684 .018
konsentrasipengikat .542 .071 .976 7.685 .005
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Lampiran 11. Perhitungan Pengikat Sukrosa
Formula I
Konsentrasi = 50 %
Penggunaan = 72 ml
Perhitungan =
× 72 ml
= 35,5 g
Formula II
Konsentrasi = 55 %
Penggunaan = 67 ml
Perhitungan =
× 67 ml
= 36,8 g
Formula III
Konsentrasi = 60 %
Penggunaan = 63,5 ml
Perhitungan =
× 63,5 ml
= 38,1 g
Formula IV
Konsentrasi = 65 %
Penggunaan = 59 ml
Perhitungan =
× 59 ml
= 38,35 g
Formula V
Konsentrasi = 70 %
Penggunaan = 54 ml
Perhitungan =
× 54 ml
= 37,8 g
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Lampiran 12. Gambar Alat – Alat Penelitian
Pengering / Oven (Tipe X-MTD) Timbangan Analitik (Ohaus)
Cube mixer (Christhoper) Pendular Granulator (Tipe YK-160)
Granul Flow Tester (GFT-100-AU-PN) Tap Density Tester (TDTF Tipe 25-2E)
65
Lampiran 12. Lanjutan …
Mesin Tablet Single Punch (Tipe TDP-6) Friability Tester (Tipe CS2)
Tablet Hardness Tester (Tipe YD-1) Alat-alat Gelas (Iwaki-Pyrex)
Rotary evaporator (Heidolph)
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Lampiran 13. Gambar Tablet Hisap Semua Formula
Formula I Formula II
Formula III Formula IV
Formula V
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