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Page 1: Petrone Group presentation 2016 · Petrone Group presentation 2016 is the one and only Petrone Group® official website containing a free- access pharmaceutical products database

Petrone Group presentation 2016

www.petrone.it is the one and only Petrone Group® official website containing a free-access pharmaceutical products database with over 37.000 Italian and Spanish items.Search it and send us a request for quote on the products you’re interested in.

Pharma, Healthcare and more

Page 2: Petrone Group presentation 2016 · Petrone Group presentation 2016 is the one and only Petrone Group® official website containing a free- access pharmaceutical products database

Index of document

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• The Group and its mission

– Petrone Group today and its evolution

– Our mission, our strength

– International and regional presence

• The Services

– Our services and some references

• Our partnerships

– Commercial

– Partnership in share capital

Page 3: Petrone Group presentation 2016 · Petrone Group presentation 2016 is the one and only Petrone Group® official website containing a free- access pharmaceutical products database

Petrone Group at a glance, today

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800 Employees Regional presence

Multilanguage Distribution Wholesale Centers

In Dublin, Barcelona and in Singapore, North and South Italy

• 6 Admin Offices

• 5 Retail Pharmacy Shops

• 8 Rehabilitation Centers

• 1 Diagnostic Imaging Unit centre

In Dublin, Barcelona and North and South Italy

• 7 Warehouses

Page 4: Petrone Group presentation 2016 · Petrone Group presentation 2016 is the one and only Petrone Group® official website containing a free- access pharmaceutical products database

Petrone Group today, a family business

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A Leading International Player in Healthcare

Private business still managed by the founding family, each with a different task

Carmine Petrone

• Founder and President

Massimo Petrone

• Lobbying, Hospital and Retail Market related activities

Pierluigi Petrone

• National and International Commercial activity and Business Development, Farmindustria’ Member

Raffaele Petrone

• Strategy, Structure & Organization

Page 5: Petrone Group presentation 2016 · Petrone Group presentation 2016 is the one and only Petrone Group® official website containing a free- access pharmaceutical products database

A business in evolution – our history

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WorldwideTrading

1920’s 1950’s 1960’s Since 2010

Complete ServiceProvider into

Healthcare Sector

Page 6: Petrone Group presentation 2016 · Petrone Group presentation 2016 is the one and only Petrone Group® official website containing a free- access pharmaceutical products database

Mission and Strengths

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• Strong international presence with deep roots in Europe

• Open minded, adaptive entrepreneurial-ship approach

• Skilled and flexible in diversifying activities

• Great proactivity in investing in new projects

• In depth expertise in national healthcare markets

• Tight link with national pharma companies

• Widely recognised reliability

• World-wide network, link with national stakeholders

• Experienced support to start-up companies

• To move into a 360° leading international service provider

• To be a first-choice global partner in Europe with our presence in Italy, Spain and Ireland

• Strengthening our widely recognised network

Our mission

Our Strenghts

Page 7: Petrone Group presentation 2016 · Petrone Group presentation 2016 is the one and only Petrone Group® official website containing a free- access pharmaceutical products database

International presence

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Extensive Direct Presence across Europe with a specific focus on Italy, Ireland, Spain and Singapore

Direct presence Through partnership in share capital

Page 8: Petrone Group presentation 2016 · Petrone Group presentation 2016 is the one and only Petrone Group® official website containing a free- access pharmaceutical products database

Always around the world

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Page 9: Petrone Group presentation 2016 · Petrone Group presentation 2016 is the one and only Petrone Group® official website containing a free- access pharmaceutical products database

Long established professional regional presence

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• Eight Rehabilitation centers, a diagnostic imaging unit, a wide range ofservices. "integrated multidisciplinary" team that takes overall care ofthe patients, according to their needs of phoniatry, physiatry,neuropsychiatry, orthopedics and a psychology, post surgery treatment,sports injury. The diagnostic unit, GEMED, provides MRI scannerdiagnosis, Spiral Ct and ecography tests.

• A consortium of private and public companies scouting R&D projects tothe benefit of patients and caregivers, participating to public fundingtenders.

• Five pharmacies, now merged into Farmacie Internazionali sas, offergreat interaction and mutual exchange. They provide 24 h delivery onrequest to public and private hospitals, shipping companies, militarypoint of care, nursing homes, embassies and internal first-aid rooms ofprivate and marine enterprises and so on.

Page 10: Petrone Group presentation 2016 · Petrone Group presentation 2016 is the one and only Petrone Group® official website containing a free- access pharmaceutical products database

Portfolio of Services, offering tailor-made solutions

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We offer “Cherry Picking” Services, modeling according to Partner needs

Businessdevelopment

Regulatory andlegal

Logistic &Pre-wholesaling

CMO CRO

Lobbying andWorldwideconnections

Accountingand financials

Venture capitalin Healthcare

Leaflet and SecondaryPackaging manufacturing facility

Biotech &Innovation

PharmacyRetail

Distribution

Page 11: Petrone Group presentation 2016 · Petrone Group presentation 2016 is the one and only Petrone Group® official website containing a free- access pharmaceutical products database

European Hub Services available at any of our locations in Italy, Spain and Ireland (1/4)

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• European location settings

• Chambre of Commerce inscription and dealings

• Minimum capital requirement settings

Company set up

Fiscal support

Legal service

Financial and Accountancy

Customs Clearance

• VAT settings

• National fiscal compliance

• Fiscal management

• Account control management• P&L statements• Financial statements and reporting• Sole agent agreement management• Invoicing in our name• Credit recovery on own account

• Consultancy on licensing agreement• Support on all current operations• Compliance to national rules and regulation assessment

• Import procedures • Relationship with Customs Authorities• Compliance to customs rules and Health Authorities

Page 12: Petrone Group presentation 2016 · Petrone Group presentation 2016 is the one and only Petrone Group® official website containing a free- access pharmaceutical products database

European Hub Services available at any of our locations in Italy, Spain and Ireland (2/4)

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Regulatory Support

• Preliminary dossier evaluation• Brand & patent analysis on demand• Direct contact with National Regulatory Authorities• Dossier and Technical File Submission• Marketing Authorization and CE maintenance

Pharmacovigilance• Pharmacovigilance activity and rule compliance on demand• Post marketing surveillance

• On demand Participation to national tenders • Targeting National Bid of interestTendering activity

Market Access• Negotiating process with national Regulatory Authorities• Supporting in registering in local/regional reimbursement list• Regional Hospital support at administrative and clinical level in

specific therapeutic area

• In/out licensing activities • World wide scouting opportunities• Negotiations skills

Business Development

Page 13: Petrone Group presentation 2016 · Petrone Group presentation 2016 is the one and only Petrone Group® official website containing a free- access pharmaceutical products database

European Hub Services available at any of our locations in Italy, Spain and Ireland (3/4)

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Secondary packaging

Logistic

Warehousing

Pre wholesaling

• Fully owned and duly authorized warehouse• Wholesaling• Stock Management, Handling, Pick & Pack• Management of entire distribution cycle• Storage of “Restricted Products” in Italy and Spain • Third – Party warehousing authorization in Spain

• Stock transfer management• Shipping in full outsourcing

• 7 distribution centers in 3 countries: Italy, Spain and Ireland

• 29,350 mq² covered surface

• 15.639 tons moved every year

• Own real estate

• Claim management• Batch recall management• Temperature control storage management• IT tailor-made support• Italian authority daily tracking system communication

Stock management

• Secondary packaging facility approved in Italy

NEW

Page 14: Petrone Group presentation 2016 · Petrone Group presentation 2016 is the one and only Petrone Group® official website containing a free- access pharmaceutical products database

European Hub Services available at any of our locations in Italy, Spain and Ireland (4/4)

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Direct distribution

Authorizations

Active promotion at Pharmacy from

Italy and Spain

• Active promotion to pharmacies through on-going Catalogueof Sales Force

• Territorial sales reps + Call Centre’s multi-list + fax + web dedicated activity

• Dedicated customer services

• GDP approved in Italy and Spain

• ISO 9001:2008 procedures in place in Milan and Naples

• Narcotic drugs and blood derivate authorization and procedures in place

• Own wholesale license in 3 countries

• KAM activity to wholesaling network• Performing tailor-made promotion campaigns• Direct Consignment to hospital, clinics

Commercialservices

• 11 Customer Care Managers, speakers in 5 languages: Spanish, English, French, German and Portuguese

• Commercial business office in Singapore

Page 15: Petrone Group presentation 2016 · Petrone Group presentation 2016 is the one and only Petrone Group® official website containing a free- access pharmaceutical products database

Our long lasting Hospital market expertise and Market Access skills

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• Negotiating process with AIFA/NHS

• Supporting in registering in local/regional reimbursement list (prontuari regionali e locali)

• Regional Hospital support at administrative and clinical level in specific therapeutic area

• National KOL network in specific therapeutic area

• Coaching and empowerment of salesforce into anti-infective hospital therapeutic area

• Hospital account management

• Tendering process

Page 16: Petrone Group presentation 2016 · Petrone Group presentation 2016 is the one and only Petrone Group® official website containing a free- access pharmaceutical products database

Some relevant references of our clients

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We offer tailor made services, in order to meet client needs.Global customers

Page 17: Petrone Group presentation 2016 · Petrone Group presentation 2016 is the one and only Petrone Group® official website containing a free- access pharmaceutical products database

Our commercial partner, Pharmaidea provides sales and distribution to almost the totality of Italian pharmacies

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The Italian complexity The solution

Pharmaidea offer full pharmacy retail sale services .

Pharmaidea is an innovative Italian pharmaceutical distributor with a complete sales network to pharmacies operating through various channels, i.e. physical reps, virtual web/call centre reps.

Pharmaidea provide a full service including

• warehouse and shipping

• stock management

• money collection

• full real time sales data always available

• sales support on pharmacies

The advantages

Italian highly fragmented market

• 80 pharmaceutical wholesalers in Italy and no pharmacy chains.

• 243 pharmaceuticals warehouses in Italy spread all around the Italian territory

• over 17.000 pharmacies

The money collection issue

• Wholesalers not always financially compliant

• Pharmacies used to unilaterally apply delay to payment terms and conditions

Huge reduction of complexity

• Zero invoicing issues

• Zero money collection issues

• Zero logistics issues

Flexibility

• Flexible cost of service (% of revenues)

• Highly adaptive to customer needs fitting the best client business model

Market link

• Open access to final customers both pharmacies and wholesalers, thanks to full customized data available.

• joint promotion – on demand - with Pharmaidea catalogue

Page 18: Petrone Group presentation 2016 · Petrone Group presentation 2016 is the one and only Petrone Group® official website containing a free- access pharmaceutical products database

SCOPE ACTIVITIES DIVISION

Contract Research & Development Organization

Global tech-based contract research and developmentorganization providing a full range of technologicalsolutions through the entire value chain of drugdiscovery and development: regulatory consulting,pharmacovigilance and marketing services, operationalservices for clinical trial (Phase I – IV) to test newmolecules and drugs, repurposing/repositioning drugsinto new therapeutical indications, through bio-mathematical algorythm, discovery and development ofMPCs (“Medicinal Product Candidates”) andinvestigational drugs preparation (InvestigationalMedicinal Product Services, "IMPs").

TCRDO Division

Manufacturing

An FDA and EMA approved plant site located inCapua (CE) producing drugs for third parties,specialized in injectable local-regional anesthetics,being worldwide leader in Dental Anesthetics filledin aseptic cartridges.

CMO Division

PharmaceuticalsOwner of Pierrel’ International MarketingAuthorizations - Orabloc®. Marketing and sales ofOrabloc®, Pierrel’ dental anesthetic.

Pharma Division

Pierrel Group Today

Page 19: Petrone Group presentation 2016 · Petrone Group presentation 2016 is the one and only Petrone Group® official website containing a free- access pharmaceutical products database

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World

Wide

WebDisease

Drug

Search

Match

THERAMetrics holding AG is a tech-based Contract Research & Development Organisation dedicated to provide a full range of technological solutions through the entire value chain of drug discovery and development. The company is listed at the Zurich Swiss Exchange (SIX:TMX)

A skilled 20 years experience in 20 countries as a partner in share capital in Contract Research Organizations

Page 20: Petrone Group presentation 2016 · Petrone Group presentation 2016 is the one and only Petrone Group® official website containing a free- access pharmaceutical products database

Heavily diversifying activities in Contract Manufacturing Organizations: partners in share capital (1/2)

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Activities Partners

• Main focus is in the field of Molecular Imaging and targeted, individualized therapy for the management of patients with serious conditions (Personalized Medicine)

• PET (Positron Emission Tomography) and SPECT (Single Photon Emission Computed Tomography) radiopharmaceuticals production and commercialization

• GLUSCAN-[18F]FDG is used to assess glucose metabolism in many diseases

• Head office in Geneva and 17 production and R&D facilities in Europe, Israel and North America

• FDA approved• Oral solid forms, sachets, oral solutions,

suppositories, nasal spray, creams

Page 21: Petrone Group presentation 2016 · Petrone Group presentation 2016 is the one and only Petrone Group® official website containing a free- access pharmaceutical products database

.

• Leaflets on reel, simple , double, triple pre-folded leaflets• Flat leaflets• Parallel and cross folded• Tagsert folded leaflets• Fold-it®

Providing packaging solutions for the Pharmaceutical industriesfor more than 45 years

Heavily diversifying activities in Contract Manufacturing Organizations: partners in share capital (2/2)

Activities

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Page 22: Petrone Group presentation 2016 · Petrone Group presentation 2016 is the one and only Petrone Group® official website containing a free- access pharmaceutical products database

Venture investments in Biotech & Innovation (1/3)

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Investing in Italian-linked lifescience companies with strong IP and solid scientific background

• R&D and manufacture of minimally invasive medical device in the treatment of varicose veins (support of OSEO), under development oncological application by thermo ablation

• Research based company that develops advanced medical imaging solution for early detection and diagnosis of cancer, in particular colon and breast

Page 23: Petrone Group presentation 2016 · Petrone Group presentation 2016 is the one and only Petrone Group® official website containing a free- access pharmaceutical products database

Venture investments in Biotech & Innovation (2/3)

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• University spin off - research and development of biotech products: selection and purification of recombinant enzymes also from marine organisms improving functional characteristics in the applicative processes

• University spin off – develops the first non-invasive solution for early diagnosis of osteoporosis and related bone diseases

Focusing on the high innovative med-tech companies

Page 24: Petrone Group presentation 2016 · Petrone Group presentation 2016 is the one and only Petrone Group® official website containing a free- access pharmaceutical products database

Venture investments in Biotech & Innovation (3/3)

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• GENPORT is the Italian Spin-off of Politecnico di Milano, developer andmanufacturer of an advanced, lightweight technology for portable and smallstationary power generation and energy storage in medical, defense, emergency,telecommunication and industrial applications.

• GENPORT combines Proton Exchange Membrane Fuel Cell (PEMFC) and LithiumIon Battery technologies, in order to provide advance power solutions to any off-grid electronic, with superior performance, reliability and satisfy suchrequirements as long life, design flexibility, high energy density, compactconfiguration, high cycling, high rate discharge, reducing to zero both noise andemissions and operating in extreme environmental conditions.

Page 25: Petrone Group presentation 2016 · Petrone Group presentation 2016 is the one and only Petrone Group® official website containing a free- access pharmaceutical products database

A footprint out of Healthcare Sector (1/2)

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• Quick No Problem Parking Spa is a company founded in 2000 which provides services ofparking management in a traditional way and in the car valet way . The company isspecialized in the management of parking facilities and services within complex structureslike city centers, airports, shopping malls, amusement parks. Quick runs approximately10,000 parking spaces throughout Italy and has grown so fast to become one of the leadingcompanies in the market. The skills acquired enables Quick to cover in full the needs relatedto the area of mobility and parking.

Si.Ge.A. Costruzioni S.p.A., part of of Quick - No Problem Parking S.p.A., is a company foundedin 1981 operating in the following sectors:• Private Building• Public Building• Infrastructures• Restoration• Maintenance

Page 26: Petrone Group presentation 2016 · Petrone Group presentation 2016 is the one and only Petrone Group® official website containing a free- access pharmaceutical products database

A footprint out of Healthcare Sector (2/2)

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Sportube is the first television on the web, completely dedicatetd to SPORT. Its mission is to become an online benchmark for

millions of sports fans and is now the official broadcaster of various Leagues Lega Pro, Lega Volley, Lega Volley Femminile,

ACI/CSAI.. It stared with the 2010 Volleyball’s World Championship and continued its activities with important national and

international championships. Sportube broadcasts all kind of content in live streaming and On Demand in high definition. Using

its professional experience in terms of production and an innovative technology Sportube allows the visualisation to an

unlimited number of users simultaneously and has experienced a positive trend in terms of users reached and views of its

contents, esteeming to reach around 25 mln contacts by September 2015.

Page 27: Petrone Group presentation 2016 · Petrone Group presentation 2016 is the one and only Petrone Group® official website containing a free- access pharmaceutical products database

We aim to be your global first-choice partner


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