Petrone Group presentation 2016
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Pharma, Healthcare and more
Index of document
2
• The Group and its mission
– Petrone Group today and its evolution
– Our mission, our strength
– International and regional presence
• The Services
– Our services and some references
• Our partnerships
– Commercial
– Partnership in share capital
Petrone Group at a glance, today
3
800 Employees Regional presence
Multilanguage Distribution Wholesale Centers
In Dublin, Barcelona and in Singapore, North and South Italy
• 6 Admin Offices
• 5 Retail Pharmacy Shops
• 8 Rehabilitation Centers
• 1 Diagnostic Imaging Unit centre
In Dublin, Barcelona and North and South Italy
• 7 Warehouses
Petrone Group today, a family business
4
A Leading International Player in Healthcare
Private business still managed by the founding family, each with a different task
Carmine Petrone
• Founder and President
Massimo Petrone
• Lobbying, Hospital and Retail Market related activities
Pierluigi Petrone
• National and International Commercial activity and Business Development, Farmindustria’ Member
Raffaele Petrone
• Strategy, Structure & Organization
A business in evolution – our history
5
WorldwideTrading
1920’s 1950’s 1960’s Since 2010
Complete ServiceProvider into
Healthcare Sector
Mission and Strengths
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• Strong international presence with deep roots in Europe
• Open minded, adaptive entrepreneurial-ship approach
• Skilled and flexible in diversifying activities
• Great proactivity in investing in new projects
• In depth expertise in national healthcare markets
• Tight link with national pharma companies
• Widely recognised reliability
• World-wide network, link with national stakeholders
• Experienced support to start-up companies
• To move into a 360° leading international service provider
• To be a first-choice global partner in Europe with our presence in Italy, Spain and Ireland
• Strengthening our widely recognised network
Our mission
Our Strenghts
International presence
7
Extensive Direct Presence across Europe with a specific focus on Italy, Ireland, Spain and Singapore
Direct presence Through partnership in share capital
Always around the world
8
Long established professional regional presence
9
• Eight Rehabilitation centers, a diagnostic imaging unit, a wide range ofservices. "integrated multidisciplinary" team that takes overall care ofthe patients, according to their needs of phoniatry, physiatry,neuropsychiatry, orthopedics and a psychology, post surgery treatment,sports injury. The diagnostic unit, GEMED, provides MRI scannerdiagnosis, Spiral Ct and ecography tests.
• A consortium of private and public companies scouting R&D projects tothe benefit of patients and caregivers, participating to public fundingtenders.
• Five pharmacies, now merged into Farmacie Internazionali sas, offergreat interaction and mutual exchange. They provide 24 h delivery onrequest to public and private hospitals, shipping companies, militarypoint of care, nursing homes, embassies and internal first-aid rooms ofprivate and marine enterprises and so on.
Portfolio of Services, offering tailor-made solutions
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We offer “Cherry Picking” Services, modeling according to Partner needs
Businessdevelopment
Regulatory andlegal
Logistic &Pre-wholesaling
CMO CRO
Lobbying andWorldwideconnections
Accountingand financials
Venture capitalin Healthcare
Leaflet and SecondaryPackaging manufacturing facility
Biotech &Innovation
PharmacyRetail
Distribution
European Hub Services available at any of our locations in Italy, Spain and Ireland (1/4)
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• European location settings
• Chambre of Commerce inscription and dealings
• Minimum capital requirement settings
Company set up
Fiscal support
Legal service
Financial and Accountancy
Customs Clearance
• VAT settings
• National fiscal compliance
• Fiscal management
• Account control management• P&L statements• Financial statements and reporting• Sole agent agreement management• Invoicing in our name• Credit recovery on own account
• Consultancy on licensing agreement• Support on all current operations• Compliance to national rules and regulation assessment
• Import procedures • Relationship with Customs Authorities• Compliance to customs rules and Health Authorities
European Hub Services available at any of our locations in Italy, Spain and Ireland (2/4)
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Regulatory Support
• Preliminary dossier evaluation• Brand & patent analysis on demand• Direct contact with National Regulatory Authorities• Dossier and Technical File Submission• Marketing Authorization and CE maintenance
Pharmacovigilance• Pharmacovigilance activity and rule compliance on demand• Post marketing surveillance
• On demand Participation to national tenders • Targeting National Bid of interestTendering activity
Market Access• Negotiating process with national Regulatory Authorities• Supporting in registering in local/regional reimbursement list• Regional Hospital support at administrative and clinical level in
specific therapeutic area
• In/out licensing activities • World wide scouting opportunities• Negotiations skills
Business Development
European Hub Services available at any of our locations in Italy, Spain and Ireland (3/4)
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Secondary packaging
Logistic
Warehousing
Pre wholesaling
• Fully owned and duly authorized warehouse• Wholesaling• Stock Management, Handling, Pick & Pack• Management of entire distribution cycle• Storage of “Restricted Products” in Italy and Spain • Third – Party warehousing authorization in Spain
• Stock transfer management• Shipping in full outsourcing
• 7 distribution centers in 3 countries: Italy, Spain and Ireland
• 29,350 mq² covered surface
• 15.639 tons moved every year
• Own real estate
• Claim management• Batch recall management• Temperature control storage management• IT tailor-made support• Italian authority daily tracking system communication
Stock management
• Secondary packaging facility approved in Italy
NEW
European Hub Services available at any of our locations in Italy, Spain and Ireland (4/4)
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Direct distribution
Authorizations
Active promotion at Pharmacy from
Italy and Spain
• Active promotion to pharmacies through on-going Catalogueof Sales Force
• Territorial sales reps + Call Centre’s multi-list + fax + web dedicated activity
• Dedicated customer services
• GDP approved in Italy and Spain
• ISO 9001:2008 procedures in place in Milan and Naples
• Narcotic drugs and blood derivate authorization and procedures in place
• Own wholesale license in 3 countries
• KAM activity to wholesaling network• Performing tailor-made promotion campaigns• Direct Consignment to hospital, clinics
Commercialservices
• 11 Customer Care Managers, speakers in 5 languages: Spanish, English, French, German and Portuguese
• Commercial business office in Singapore
Our long lasting Hospital market expertise and Market Access skills
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• Negotiating process with AIFA/NHS
• Supporting in registering in local/regional reimbursement list (prontuari regionali e locali)
• Regional Hospital support at administrative and clinical level in specific therapeutic area
• National KOL network in specific therapeutic area
• Coaching and empowerment of salesforce into anti-infective hospital therapeutic area
• Hospital account management
• Tendering process
Some relevant references of our clients
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We offer tailor made services, in order to meet client needs.Global customers
Our commercial partner, Pharmaidea provides sales and distribution to almost the totality of Italian pharmacies
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The Italian complexity The solution
Pharmaidea offer full pharmacy retail sale services .
Pharmaidea is an innovative Italian pharmaceutical distributor with a complete sales network to pharmacies operating through various channels, i.e. physical reps, virtual web/call centre reps.
Pharmaidea provide a full service including
• warehouse and shipping
• stock management
• money collection
• full real time sales data always available
• sales support on pharmacies
The advantages
Italian highly fragmented market
• 80 pharmaceutical wholesalers in Italy and no pharmacy chains.
• 243 pharmaceuticals warehouses in Italy spread all around the Italian territory
• over 17.000 pharmacies
The money collection issue
• Wholesalers not always financially compliant
• Pharmacies used to unilaterally apply delay to payment terms and conditions
Huge reduction of complexity
• Zero invoicing issues
• Zero money collection issues
• Zero logistics issues
Flexibility
• Flexible cost of service (% of revenues)
• Highly adaptive to customer needs fitting the best client business model
Market link
• Open access to final customers both pharmacies and wholesalers, thanks to full customized data available.
• joint promotion – on demand - with Pharmaidea catalogue
SCOPE ACTIVITIES DIVISION
Contract Research & Development Organization
Global tech-based contract research and developmentorganization providing a full range of technologicalsolutions through the entire value chain of drugdiscovery and development: regulatory consulting,pharmacovigilance and marketing services, operationalservices for clinical trial (Phase I – IV) to test newmolecules and drugs, repurposing/repositioning drugsinto new therapeutical indications, through bio-mathematical algorythm, discovery and development ofMPCs (“Medicinal Product Candidates”) andinvestigational drugs preparation (InvestigationalMedicinal Product Services, "IMPs").
TCRDO Division
Manufacturing
An FDA and EMA approved plant site located inCapua (CE) producing drugs for third parties,specialized in injectable local-regional anesthetics,being worldwide leader in Dental Anesthetics filledin aseptic cartridges.
CMO Division
PharmaceuticalsOwner of Pierrel’ International MarketingAuthorizations - Orabloc®. Marketing and sales ofOrabloc®, Pierrel’ dental anesthetic.
Pharma Division
Pierrel Group Today
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World
Wide
WebDisease
Drug
Search
Match
THERAMetrics holding AG is a tech-based Contract Research & Development Organisation dedicated to provide a full range of technological solutions through the entire value chain of drug discovery and development. The company is listed at the Zurich Swiss Exchange (SIX:TMX)
A skilled 20 years experience in 20 countries as a partner in share capital in Contract Research Organizations
Heavily diversifying activities in Contract Manufacturing Organizations: partners in share capital (1/2)
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Activities Partners
• Main focus is in the field of Molecular Imaging and targeted, individualized therapy for the management of patients with serious conditions (Personalized Medicine)
• PET (Positron Emission Tomography) and SPECT (Single Photon Emission Computed Tomography) radiopharmaceuticals production and commercialization
• GLUSCAN-[18F]FDG is used to assess glucose metabolism in many diseases
• Head office in Geneva and 17 production and R&D facilities in Europe, Israel and North America
• FDA approved• Oral solid forms, sachets, oral solutions,
suppositories, nasal spray, creams
.
• Leaflets on reel, simple , double, triple pre-folded leaflets• Flat leaflets• Parallel and cross folded• Tagsert folded leaflets• Fold-it®
Providing packaging solutions for the Pharmaceutical industriesfor more than 45 years
Heavily diversifying activities in Contract Manufacturing Organizations: partners in share capital (2/2)
Activities
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Venture investments in Biotech & Innovation (1/3)
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Investing in Italian-linked lifescience companies with strong IP and solid scientific background
• R&D and manufacture of minimally invasive medical device in the treatment of varicose veins (support of OSEO), under development oncological application by thermo ablation
• Research based company that develops advanced medical imaging solution for early detection and diagnosis of cancer, in particular colon and breast
Venture investments in Biotech & Innovation (2/3)
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• University spin off - research and development of biotech products: selection and purification of recombinant enzymes also from marine organisms improving functional characteristics in the applicative processes
• University spin off – develops the first non-invasive solution for early diagnosis of osteoporosis and related bone diseases
Focusing on the high innovative med-tech companies
Venture investments in Biotech & Innovation (3/3)
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• GENPORT is the Italian Spin-off of Politecnico di Milano, developer andmanufacturer of an advanced, lightweight technology for portable and smallstationary power generation and energy storage in medical, defense, emergency,telecommunication and industrial applications.
• GENPORT combines Proton Exchange Membrane Fuel Cell (PEMFC) and LithiumIon Battery technologies, in order to provide advance power solutions to any off-grid electronic, with superior performance, reliability and satisfy suchrequirements as long life, design flexibility, high energy density, compactconfiguration, high cycling, high rate discharge, reducing to zero both noise andemissions and operating in extreme environmental conditions.
A footprint out of Healthcare Sector (1/2)
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• Quick No Problem Parking Spa is a company founded in 2000 which provides services ofparking management in a traditional way and in the car valet way . The company isspecialized in the management of parking facilities and services within complex structureslike city centers, airports, shopping malls, amusement parks. Quick runs approximately10,000 parking spaces throughout Italy and has grown so fast to become one of the leadingcompanies in the market. The skills acquired enables Quick to cover in full the needs relatedto the area of mobility and parking.
Si.Ge.A. Costruzioni S.p.A., part of of Quick - No Problem Parking S.p.A., is a company foundedin 1981 operating in the following sectors:• Private Building• Public Building• Infrastructures• Restoration• Maintenance
A footprint out of Healthcare Sector (2/2)
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Sportube is the first television on the web, completely dedicatetd to SPORT. Its mission is to become an online benchmark for
millions of sports fans and is now the official broadcaster of various Leagues Lega Pro, Lega Volley, Lega Volley Femminile,
ACI/CSAI.. It stared with the 2010 Volleyball’s World Championship and continued its activities with important national and
international championships. Sportube broadcasts all kind of content in live streaming and On Demand in high definition. Using
its professional experience in terms of production and an innovative technology Sportube allows the visualisation to an
unlimited number of users simultaneously and has experienced a positive trend in terms of users reached and views of its
contents, esteeming to reach around 25 mln contacts by September 2015.
We aim to be your global first-choice partner