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Page 1: PATHOBIOLOGIST JUL– SEP 2018

PATHOBIOLOGIST SEPTEMBER 2018 | Page 1

Department of Pathobiology Monthly Newsletter

JUL– SEP 2018 PATHOBIOLOGIST

CHAIR’S NOTE

As unbelievable as it may sound, fall has just arrived! I am just not sure what happened to summer because it was too short and now we have to wait for another 270 days for the arrival of next summer. In the meantime, the academic year has started in full force, so I wanted to take this opportunity and welcome our new graduate students to the Pathobiology family. The new academic year also began with a major event for Pathobiology, which was Dr. Nagy’s retirement. Dr. Nagy mentored several generations of veterinary virologists and, by all accounts, she has been the top veterinary virologist in Canada. Over the last three decades, she has also taught several thousand OVC graduates and, indeed, many of our faculty. We won’t be able to easily replace the wis-dom, knowledge and experience that she contributed to Pathobiology, but on behalf of the Department, I would like to wish her the very best.

As a quick note, there will be a pizza lunch on the 25th to welcome the new students and, moreover, it is an occasion for Pathobiology to gather, share some food, have fun, reconnect and establish new connections. Please try to make time to be there and enjoy.

Best, Shayan Sharif

@OVCPathobiology

IN THIS ISSUE Congratulations Page 1

News and Tweets Page 2

Recent Publications Page 2

Congratulations...cont’d Page 3

Grad Corner Page 3

Upcoming Events Page 4

OVC News Centres/Links Page 4

Department Reminders Page 4

Dr. Byram Bridle received an Innovation Grant worth $200,000 over two years, which is jointly funded by the Canadian Cancer Society Research Institute and CIHR (Institute of Cancer Research). The project is entitled "Combining Oncolytic Virotherapy and Epigenetic Modifiers to Treat Acute Leukemias".

Drs. Byram Bridle and Sarah Wootton received an Operating Grant worth $120,000 over two years, which is jointly funded by the Cancer Research Society and CIHR (Institute of Cancer Research). The project is entitled "Treatment of Osteosarcoma Lung Metastases with an Infected Cancer Cell Vaccine"

Dr. Dale Smith, in the Ontario Veterinary College’s Department of Pathobiology, was named University Professor Emerita at the University of Guelph Convocation ceremonies in June. | OVC Bulletin

OVC Professor, Dr. Carlton Gyles, Honoured Nationally for Outstanding Contributions to Veterinary Profession | U of G News

Congrats Doug Campbell on his retirement. A huge turn out reflects the quality of the man and the impact he’s had on the department, CWHC, and wildlife pathology in Canada.

Betty-Anne McBey, a technician in the Department of Pathobiology, received the Award for Excellence in Wellness, Health and Safety. McBey has spent more than 25 years ensuring the safety and operations of the department’s research and teaching labs. | OVC Bulletin

Pathobiology congratulates the new ACVP diplomates in Anatomic Pathology (Amanda Mansz, Courtney Schott, Emma Borkowski, Rebecca Egan and Russell Fraser) and Clinical Pathology (Karlee Craig and William Gow). Seven new diplomates in one year is an outstanding result, and the department is very proud of their accomplishments. (pictured below)

ABOVE: Dr. Dale Smith

ABOVE: Betty-Anne McBey (left) with Dr. Franco Vaccarino (right) U of G President and Vice-Chancellor

ABOVE: Dr. Carlton Gyles (left) and Doug Campbell (right)

ABOVE: Dr. Byram Bridle (left) and Dr. Sarah Wootton (right)

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Page 2 | PATHOBIOLOGIST SEPTEMBER 2018

@OVCPathobiology

NEWS & TWEETS

Deadly 'fox' tapeworm found in Ontario can kill dogs and humans: Veterinary Parasitologist and media go-to-guy for parasite stories Dr. Andrew Peregrine was at it again, talking to CBC about fox tapeworms that can infect dogs and humans. Story and audio link of interview below. | CBC News

Breeding Livestock for Climate Resilience: We enjoyed visiting with Food from Thought principal investigator Bonnie Mallard at the Elora Research Station to check out some of her work. Bonnie's research with us explores climate resiliency in livestock: | @UofG_Fft

Helping pork producers lower feed costs: Great story on work done by Dr. Brandon Lillie, Dr. Vahab Farzan & their collaborators whose research is trying to help pork producers lower feed costs without impacting health & productivity | Farms.com

Raccoons experiencing high blood sugar levels from eating our food: Co-author Claire Jardine, a veterinarian and assistant professor from the University of Guelph, collected blood samples from 60 anaesthetized live raccoons. | CBC News

Great new study by Dr. Laura Bourque done in the lab of Dr. Jeff Caswell looking at the impact of oil components on innate immunity in the respiratory system as it pertains to oil spills in the ocean and their impact on cetaceans. | Science Direct

Canadian researchers team up to fight canine osteosarcoma: DOGBONe aims to identify biomarkers in patients with osteosarcoma. “The dogs are a model for the worst of the human disease,” said Geoffrey A. Wood, DVM, Ph.D., DVSc (pathology), of the OVC’s Department of Pathobiology. “Right now, the information we find out in human osteosarcoma serves as a model for the dogs. There’s an opportunity to go both ways between the species, for the benefit of both.” | Veterinary Practice News | @LangevinEqui

Great to welcome Dr. Mona Nemer, Canada’s Chief Science Advisor to OVC Pathobiology as part of her U of G visit. She toured the Pathobiology / AHL building, our research animal isolation building, CPHAZ and more with PABI Chair S. Sharif and oth-ers. | @OVCPathobiology

Helping Solve the Wildest Crimes CSI Veterinary Edition. Very cool story out of the Washington Post. OVC Pathobiology trains Veterinary pathologists who can help solve the wildest crimes. | Washington Post

RECENT PUBLICATIONS G. Wood, et al: Cross-species genomics identifies DLG2 as a tumor suppressor in osteosarcoma. | PubMed S. Sharif, B. Mallard, et al: Type I and type II cytokine production of CD4+ T-cells in immune response biased dairy cattle around calving. | PubMed S. Wootton, B. Bridle, et al: Use of Preci-sion-Cut Lung Slices as an Ex Vivo Tool for Evaluating Viruses and Viral Vectors for Gene and Oncolytic Therapy. | PubMed J. Caswell JL, L. Bassel, J. Rothenburger, et al: Observational Study Design in Veterinary Pathology, Part 1: Study Design. | PubMed B. Plattner, K. Stinson, M. Baquero, et al: Resilience to infection by Mycobacterium avium subspecies paratuberculosis following direct intestinal inoculation in calves. | PubMed S. Keller, M. Hwang, et al: Characterization of the canine immunoglobulin heavy chain repertoire by next generation se-quencing. | PubMed C. Jardine, J. Barta, L. Susta, N. Nemeh et al: High Prevalence of Mycoplasma and Eimeria Species in Free-Ranging Eastern Wild Turkeys ( Meleagris gallopavo sil-vestris) in Ontario, Canada. | PubMed

Congratulations to Dr. Lisa Santry

(postdoctoral fellow in the Wootton lab) for publishing a portion of her PhD research in a co-first authored paper in the high-impact journal Clinical Cancer Research (impact factor: 10.2). Co-authors included Jacob van Vloten (PhD student in the Wootton/Bridle labs) and Amanda AuYeung (MSc student in the Bridle lab). Senior authors included Drs. Byram Bridle and Sarah Wootton. This research represents a paradigm-changing approach to oncolytic virotherapy that emerged from a strategic collaboration that leveraged unique expertise within the Ontario Veterinary College. | AACR Publications

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PATHOBIOLOGIST SEPTMENT 2018 | Page 3

...continued

GRAD CORNER

WELCOME NEW GRADS

DVS Students Melanie Iverson with Dr. B. Lillie Katy Morrison with Dr. D. Wood

PhD Students Shannon Beard with Dr. B. Mallard Jessuca Joshua with Dr. J. Caswell Heng Kang with Dr. J. Beeler-Marfisi Sugandha Raj with Dr. S. Sharif

MSc Students

Hussain Alhunfush with Dr. R. Kulkarni Tess Altvater-Hughes with Dr. B. Mallard Elaine Klafuric with Dr. B. Bridle Joseph Nowlan with Dr. J. Lumsden Laura O’Shaughnessy-Hunter

with Dr. S. Weese Amira Rghei with Dr. S. Wootton Sarah Robinson with Dr. C. Jardine Jessica Rotolo with Dr. J. Barta Beth Zeldenrust with Dr. J. Barta

USEFUL LINKS Pathobiology Graduate Student Handbook Graduate and Postdoctoral Studies Information on how best to apply to

Graduate Studies in Pathobiology International Student Handbook

(UG Student Life) Departmental Forms for Graduate

Examinations International Student Advisor

GRADUATE PROGRAM ASSISTANT

Donna Kangas Stewart Building, Room 2509, Ext. 54725, [email protected]. For more graduate information please go to the Shared Administrative Services website http://ovc.uoguelph.ca/sas.

Congratulations to Beth MacMillan (OVC Class of 2018) for receiving an award from the American College of Veterinary Pathology in recognition of her outstanding achievement, proficiency and interest in veterinary pathology.

Congrats to Pathobiology PhD student Carina Cooper for winning best grad student poster at the Calgary International Equine Symposium for her work on Equine Herpesvirus. | @OVCPathobiology

Great job by our summer students at the CORE Poster Day, some of which can be seen in tweet, and congrats!! to Grace Thorton, Julie Calvert, and Sydney Swartz who won prizes for their posters. | @OVCPathobiology

HUGE congrats to incoming Pathobiology PhD student Sugandha Raj for winning one of the inaugural very prestigious Arrell Food Institute Scholarships!!!! Expecting great things from her research on avian influenza virus. | Arell Food Institute Jamie Rothenberger was honoured to have been selected as the U of G recipient of the Governor General Academic Gold Medal and the D.F. Forester Medal for my PhD work in Pathobiology. | @JRothenberger

Congratulations to PhD student Ashley Ross (co-advised by Drs. Bridle and Wootton) for winning the speed-talk competition at the recent annual scientific meeting of the Canadian Society for Immunology. In this competition, students were given only one minute to summarize their research. Ashley was the only award recipient out of approximately fifty competitors.

Congrats to Genna Lumsden from Pathobiology on being one of the grad student winners at CPHAZ 2018 |@CPHAZ Congrats to Ryan Snyder (2nd) and Rachel Imai (3rd) for their student oral presentation awards at the American Association of Veterinary Parasitologists 63rd Annual Meeting in Denver, Colorado this past July.

Congratulations to Maria Rosales Gerpe for receiving an ‘Outstanding Poster Presentation Award’ from the American Society of Gene & Cell Therapy.

Congrats to our Pathobiology graduate students that won awards at the OVC Grad Student Research Symposium: Emma Borkowski - 1st (PhD Poster) Shannon French - 2nd(PhD Poster) Alex Leveille - 2nd(PhD Oral) Ellie Milnes,1st (DVSc Oral) | OVC Bulletin

NEW GRAD PIZZA PARTY

SEP 25 at 12 pm in PAHL 1800

All pathobiology faculty, staff and graduate students welcome!

ABOVE: Beth MacMillan (right)

ABOVE: Corina Cooper (left)

ABOVE: Sugandha Raj

ABOVE: Jamie Rothenberger

ABOVE: Ryan Snyder (back) and Rachel Imai (front)

Page 4: PATHOBIOLOGIST JUL– SEP 2018

Page 4 | PATHOBIOLOGIST SEPTEMBER 2018

UPCOMING EVENTS

DEPARTMENT REMINDERS and NOTICES

Marni Struyk Administrative Assistant to the Chair and Faculty Room 3840 PAHL Ext 54755 [email protected]

Melana Nam, Operations Manager

Pathobiology & Administrative Manager OVC SAS HR Services Room 3838 PAHL Ext 54703 [email protected]

PATHOBIOLOGY SEMINARS Seminars will take place at 11:30 am in PAHL room 1810 unless otherwise notes

Oct 12 Ryan Snyder Host: J. Barta

Oct 19 TBD Host: S. Sharif Nov 9 Jonathon Kotwa Host: A. Peregrine

Nov 16 Emma Borowski Host: A. Peregrine

Nov 23 Dr. Samaria Mubareka Sunnybrook Health Sciences Centre Host: S. Sharif

Nov 30 PABI *6440/6450 Student Presentations 1. Tyler Greer Host: G. Wood / J. MacInnes

OVC and U of G EVENTS

Sep 24 United Way Kick Off | details

Sep 26-27 Rabies Titre Clinics | details

Sep 27 CCSAW Animal Behaviour Welfare Seminar 12:30-1:25pm PAHL 1800| details

Oct 2 OVC Community event 12:30-1:30pm PAHL 1800

Oct 1-7 Mental Health Awareness week |details

Oct 11 CCVI/SOCRA Cardiovascular | details Research Day 12-5pm PAHL 1800

Nov 6 The Derry Dialogues - Living Among Intelligent Machines 5:30-7 pm | details

Nov 8 Recruit Guelph Career Fair 10a m- 3 pm UC | details

SAS UPDATE Support for completing expense claims (ECS) and complex purchase orders IS coming An announcement will follow with the schedule. In the meantime, please continue to use the eRequest form to submit your purchase or ex-pense claim questions or submissions. | OVC Bulletin FACULTY The new UGFA Collective Agreement is now available > click here

BICYCLES It has been brought to our attention that there have been bicycles brought into PAHL Bldg. 89 on the lower floors and kept inside in the stairwells.

This practice is currently happening and due to the Ontario Fire Code is not allowed.

Please remove all bicycles from inside of the building.

Outside bicycle racks are provided by the University and available on the South side of the building in the shelter.

Per Policy Statement 2.1 “Bicycles shall not be stored inside University buildings unless the storage spaces is specifically designed for such purposes and has been previously approved (e.g. residence bike rooms).”

October 24, 2018

2018 Gairdner Lecture : Dr. Azim Surani

Director of Germline and Epigenetics Research, Wellcome Trust Cancer Research, UK Gurdon Institute, Marshall-Walton Profes-sor, University of Cambridge. > event poster

Time: 10:30-12:30 Location: PAHL 1800

| UPCOMING EVENTS | TRAINING | STAFF ATHLETIC FEE SUBSIDY |

Picture your research photo in an upcoming Research Communications

publication! | details

NEWS from OVC Centres and More OVC Bulletin Campbell Centre for Animal Welfare Centre for Cardiovascular

Investigations Centre for Public Health and Zoonoses Equine Guelph Institute for Comparative

Cancer Investigations OAHN OVC Pet Trust Poultry Health Research Network B4uGetaPet U of G News Worms and Germs

OTHER USEFUL LINKS Grant Opportunities Call for Nominations Ontario Animal Health Network

Go to Unite Way Campus Events

United Way Guelph Wellinton Dufferin

Contact Brandon

News items

Awards Events TO ADD TO TWITTER Contact Nathalie

newsletter submissions

website updates

research posters research websites

teaching rooms and resources

Ayumi Matsuyama welcomed her daughter Anna last November 10. Pictured above with her big brother Ayato.

Kathie Clow, Pathobiology United Way Rep